rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | P61965 | 334 | WDR5_MOUSE WD repeat-containing protein 5 OS=... | 114 | 0.00001 | 52 | 27 | 47 | GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; ISS:UniProtKB. | | | | | | | | | | GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0001501; P:skeletal system development; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 32 | P61964 | 334 | WDR5_HUMAN WD repeat-containing protein 5 OS=... | 114 | 0.00001 | 52 | 27 | 47 | GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:BHF-UCL.::GO:0071339; C:MLL1 complex; IDA:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.::GO:0051568; P:histone H3-K4 methylation; IDA:UniProtKB.::GO:0043984; P:histone H4-K16 acetylation; IDA:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; IDA:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 33 | Q5M786 | 334 | WDR5_XENTR WD repeat-containing protein 5 OS=... | 121 | 0.000008 | 52.8 | 26 | 46 | GO:0000123; C:histone acetyltransferase complex; ISS:UniProtKB.::GO:0071339; C:MLL1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; ISS:UniProtKB. | | | | | | | | | | GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0034968; P:histone lysine methylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 34 | Q54D08 | 304 | LST8_DICDI Protein LST8 homolog OS=Dictyostel... | 123 | 0.0004 | 47 | 28 | 51 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0031932; C:TORC2 complex; IPI:dictyBase. | | | | | | | | | | | | | | | | | | | | GO:0007190; P:activation of adenylate cyclase activity; IMP:dictyBase.::GO:0032148; P:activation of protein kinase B activity; IMP:dictyBase.::GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:dictyBase.::GO:0043520; P:regulation of myosin II filament assembly; IMP:dictyBase. | 35 | Q90ZL4 | 410 | LIS1_XENLA Lissencephaly-1 homolog OS=Xenopus... | 201 | 0.00008 | 49.7 | 21 | 42 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 36 | A2CEH0 | 490 | POC1B_DANRE POC1 centriolar protein homolog B... | 166 | 0.000005 | 53.9 | 25 | 40 | | | | | | | | | | | | | | | | | | | | | GO:0042384; P:cilium assembly; ISS:UniProtKB.::GO:0060287; P:epithelial cilium movement involved in determination of left/right asymmetry; IMP:ZFIN.::GO:0003014; P:renal system process; IMP:ZFIN. | 37 | Q6GMD2 | 305 | WDR61_XENLA WD repeat-containing protein 61 O... | 203 | 9.7 | 33.1 | 21 | 40 | GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB. | 38 | Q6NZH4 | 410 | LIS1_XENTR Lissencephaly-1 homolog OS=Xenopus... | 201 | 0.00007 | 50.1 | 21 | 42 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 39 | Q55563 | 1693 | Y163_SYNY3 Uncharacterized WD repeat-containi... | 89 | 1.6 | 36.2 | 22 | 45 | | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | | 40 | Q6PBD6 | 305 | WDR61_XENTR WD repeat-containing protein 61 O... | 155 | 0.34 | 37.7 | 25 | 45 | GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB. | 41 | Q5ZJH5 | 305 | WDR61_CHICK WD repeat-containing protein 61 O... | 155 | 4.5 | 34.3 | 26 | 42 | GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB. | 42 | Q12788 | 808 | TBL3_HUMAN Transducin beta-like protein 3 OS=... | 464 | 0.007 | 43.9 | 20 | 36 | GO:0005730; C:nucleolus; IDA:HPA.::GO:0032040; C:small-subunit processome; IEA:InterPro. | | | | | | | | | | GO:0005057; F:receptor signaling protein activity; TAS:ProtInc. | | | | | | | | | | GO:0007199; P:G-protein signaling, coupled to cGMP nucleotide second messenger; TAS:ProtInc.::GO:0006364; P:rRNA processing; IEA:InterPro. | 43 | Q9V3J8 | 361 | WDS_DROME Protein will die slowly OS=Drosophi... | 123 | 0.0005 | 47 | 26 | 45 | GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IPI:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0048188; C:Set1C/COMPASS complex; IDA:FlyBase. | | | | | | | | | | | | | | | | | | | | GO:0051568; P:histone H3-K4 methylation; IMP:FlyBase.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IGI:FlyBase. | 44 | A8X8C6 | 368 | TG125_CAEBR WD repeat-containing protein tag-... | 116 | 0.004 | 44.3 | 23 | 46 | | | | | | | | | | | | | | | | | | | | | | 45 | Q4V7A0 | 305 | WDR61_RAT WD repeat-containing protein 61 OS=... | 158 | 0.66 | 37 | 26 | 42 | GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB. | 46 | Q8NBT0 | 407 | POC1A_HUMAN POC1 centriolar protein homolog A... | 136 | 0.00002 | 52 | 25 | 46 | GO:0005814; C:centriole; IDA:UniProtKB.::GO:0005932; C:microtubule basal body; IDA:UniProtKB. | | | | | | | | | | | | | | | | | | | | | 47 | Q9ERF3 | 305 | WDR61_MOUSE WD repeat-containing protein 61 O... | 158 | 0.66 | 37 | 26 | 42 | GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB. | 48 | P56094 | 682 | TUP1_KLULA General transcriptional corepresso... | 233 | 0.00006 | 50.4 | 24 | 39 | | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 49 | Q9GZS3 | 305 | WDR61_HUMAN WD repeat-containing protein 61 O... | 158 | 1 | 36.2 | 26 | 42 | GO:0016593; C:Cdc73/Paf1 complex; IDA:UniProtKB.::GO:0055087; C:Ski complex; IDA:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0080182; P:histone H3-K4 trimethylation; IMP:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; IDA:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; IMP:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; IMP:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB. | 50 | Q2TBP4 | 407 | POC1A_BOVIN POC1 centriolar protein homolog A... | 136 | 0.00005 | 50.4 | 24 | 45 | GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | | 51 | Q32LN7 | 305 | WDR61_BOVIN WD repeat-containing protein 61 O... | 158 | 0.97 | 36.6 | 26 | 42 | GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB. | 52 | Q5U2W5 | 800 | TBL3_RAT Transducin beta-like protein 3 OS=Ra... | 444 | 0.004 | 44.7 | 22 | 38 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0032040; C:small-subunit processome; IEA:InterPro. | | | | | | | | | | | | | | | | | | | | GO:0006364; P:rRNA processing; IEA:InterPro. | 53 | Q8JZX3 | 405 | POC1A_MOUSE POC1 centriolar protein homolog A... | 206 | 0.00003 | 51.2 | 24 | 38 | GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | | 54 | Q17963 | 376 | TG125_CAEEL WD repeat-containing protein tag-... | 122 | 0.019 | 42 | 21 | 43 | GO:0005634; C:nucleus; IDA:WormBase. | | | | | | | | | | | | | | | | | | | | GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0051568; P:histone H3-K4 methylation; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase. | 55 | Q5RD06 | 451 | POC1B_PONAB POC1 centriolar protein homolog B... | 154 | 0.000008 | 53.1 | 23 | 42 | GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0042384; P:cilium assembly; ISS:UniProtKB. | 56 | Q5RE95 | 330 | WDR5B_PONAB WD repeat-containing protein 5B O... | 141 | 0.000002 | 54.3 | 26 | 46 | | | | | | | | | | | | | | | | | | | | | | 57 | Q8TC44 | 478 | POC1B_HUMAN POC1 centriolar protein homolog B... | 154 | 0.000001 | 55.5 | 25 | 43 | GO:0005814; C:centriole; IDA:UniProtKB.::GO:0005932; C:microtubule basal body; IDA:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0042384; P:cilium assembly; IMP:UniProtKB. | 58 | Q9VZF4 | 1326 | FBXW7_DROME F-box/WD repeat-containing protei... | 74 | 0.0006 | 47.4 | 27 | 51 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; NAS:FlyBase. | | | | | | | | | | GO:0030332; F:cyclin binding; TAS:FlyBase. | | | | | | | | | | GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0008054; P:cyclin catabolic process; TAS:FlyBase.::GO:0042023; P:DNA endoreduplication; IMP:FlyBase.::GO:0060253; P:negative regulation of glial cell proliferation; IGI:FlyBase.::GO:0045926; P:negative regulation of growth; IMP:FlyBase.::GO:0007096; P:regulation of exit from mitosis; TAS:FlyBase.::GO:0007088; P:regulation of mitosis; IMP:FlyBase.::GO:0030162; P:regulation of proteolysis; TAS:FlyBase. | 59 | Q86VZ2 | 330 | WDR5B_HUMAN WD repeat-containing protein 5B O... | 141 | 0.000004 | 53.9 | 26 | 46 | | | | | | | | | | | | | | | | | | | | | | 60 | P16649 | 713 | TUP1_YEAST General transcriptional corepresso... | 145 | 0.078 | 40.4 | 25 | 43 | GO:0017053; C:transcriptional repressor complex; IDA:SGD. | | | | | | | | | | GO:0042393; F:histone binding; IDA:SGD.::GO:0042826; F:histone deacetylase binding; IDA:SGD.::GO:0036033; F:mediator complex binding; IDA:SGD.::GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IDA:SGD.::GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; IDA:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD. | | | | | | | | | | GO:0043486; P:histone exchange; IMP:SGD.::GO:0035955; P:negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0001198; P:negative regulation of mating-type specific transcription from RNA polymerase II promoter; IMP:SGD.::GO:0000433; P:negative regulation of transcription from RNA polymerase II promoter by glucose; IMP:SGD.::GO:0007070; P:negative regulation of transcription from RNA polymerase II promoter during mitosis; IMP:SGD.::GO:0016584; P:nucleosome positioning; IDA:SGD.::GO:2000531; P:regulation of fatty acid biosynthetic process by regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:2001020; P:regulation of response to DNA damage stimulus; IMP:SGD.::GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; IMP:SGD.::GO:0061392; P:regulation of transcription from RNA polymerase II promoter in response to osmotic stress; IMP:SGD. | 61 | Q5REG7 | 410 | LIS1_PONAB Platelet-activating factor acetylh... | 201 | 0.0002 | 48.5 | 20 | 43 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. |