Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR127C
Length:
853
Number of sequences:
5887
Description:
YLR127C APC2 SGDID:S000004117, Chr XII from 398319-395758, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; component of the catalytic core of the APC/C; has similarity to cullin Cdc53p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q12440    853   APC2_YEAST Anaphase-promoting complex subunit...8530     1750     100     100GO:0005680; C:anaphase-promoting complex; IDA:SGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; IMP:SGD.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008054; P:cyclin catabolic process; IMP:SGD.::GO:0010458; P:exit from mitosis; IGI:SGD.::GO:0007091; P:mitotic metaphase/anaphase transition; IGI:SGD.::GO:0016567; P:protein ubiquitination; IMP:SGD.
2Q8H1U5    865   APC2_ARATH Anaphase-promoting complex subunit...5674e-28     125     24     44GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005819; C:spindle; IDA:UniProtKB.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0009561; P:megagametogenesis; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
3Q9UJX6    822   ANC2_HUMAN Anaphase-promoting complex subunit...6641e-25     117     23     41GO:0005680; C:anaphase-promoting complex; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; TAS:ProtInc.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008054; P:cyclin catabolic process; TAS:ProtInc.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.::GO:0031915; P:positive regulation of synaptic plasticity; ISS:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; TAS:ProtInc.
4Q8BZQ7    837   ANC2_MOUSE Anaphase-promoting complex subunit...6612e-22     107     23     41GO:0005680; C:anaphase-promoting complex; ISS:UniProtKB.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0090129; P:positive regulation of synapse maturation; IDA:UniProtKB.::GO:0031915; P:positive regulation of synaptic plasticity; IDA:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
5Q874R3    681   APC2_SCHPO Anaphase-promoting complex subunit...5766e-17     89     24     40GO:0005680; C:anaphase-promoting complex; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; IC:PomBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008054; P:cyclin catabolic process; IC:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0016567; P:protein ubiquitination; IC:PomBase.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IC:PomBase.
6Q551S9    907   APC2_DICDI Anaphase-promoting complex subunit...6050.0000000005     67     21     41GO:0005680; C:anaphase-promoting complex; ISS:dictyBase.::GO:0005829; C:cytosol; ISS:dictyBase.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; IC:dictyBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0016567; P:protein ubiquitination; IC:dictyBase.
7P34514    731   APC2_CAEEL Anaphase-promoting complex subunit...3570.0000006     57     20     40GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040039; P:inductive cell migration; IMP:WormBase.::GO:0007126; P:meiosis; IMP:WormBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
8Q24311    774   CUL1_DROME Cullin homolog 1 OS=Drosophila mel...2230.047     41.2     26     46GO:0019005; C:SCF ubiquitin ligase complex; NAS:FlyBase.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IGI:FlyBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
9O13790    767   CUL1_SCHPO Cullin-1 OS=Schizosaccharomyces po...1720.078     40.4     25     43GO:0005829; C:cytosol; IDA:PomBase.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:PomBase.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0032876; P:negative regulation of DNA endoreduplication; IMP:PomBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IC:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.
10Q9WTX6    776   CUL1_MOUSE Cullin-1 OS=Mus musculus (Mouse). ...1141.6     36.2     26     50GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IC:MGI.
GO:0006915; P:apoptotic process; IMP:MGI.::GO:0008283; P:cell proliferation; IMP:MGI.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0009887; P:organ morphogenesis; IMP:MGI.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
11Q5R4G6    776   CUL1_PONAB Cullin-1 OS=Pongo abelii (Sumatran...1141.7     36.2     26     50GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
12Q13616    776   CUL1_HUMAN Cullin-1 OS=Homo sapiens (Human). ...1141.7     36.2     26     50GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0007050; P:cell cycle arrest; TAS:ProtInc.::GO:0000080; P:G1 phase of mitotic cell cycle; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0008629; P:induction of apoptosis by intracellular signals; TAS:ProtInc.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0016567; P:protein ubiquitination; IDA:UniProtKB.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
13Q9C9L0    732   CUL3B_ARATH Cullin-3B OS=Arabidopsis thaliana...1144     34.7     26     45GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0009793; P:embryo development ending in seed dormancy; IGI:TAIR.::GO:0009960; P:endosperm development; IGI:TAIR.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
14Q9ZVH4    732   CUL3A_ARATH Cullin-3A OS=Arabidopsis thaliana...1498.2     33.9     23     44GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.::GO:0005829; C:cytosol; IDA:TAIR.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0009793; P:embryo development ending in seed dormancy; IGI:TAIR.::GO:0009960; P:endosperm development; IGI:TAIR.::GO:0009911; P:positive regulation of flower development; IMP:TAIR.::GO:0009639; P:response to red or far red light; IMP:TAIR.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
15O13957    328   YEHG_SCHPO Uncharacterized protein C23H4.16c ...12710     33.1     21     43GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
records
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