Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR121C
Length:
508
Number of sequences:
5887
Description:
YLR121C YPS3 SGDID:S000004111, Chr XII from 390270-388744, Genome Release 64-1-1, reverse complement, Verified ORF, "Aspartic protease, member of the yapsin family of proteases involved in cell wall growth and maintenance; attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91P27821    387   PEPA2_RABIT Pepsin II-2/3 OS=Oryctolagus cuni...3414e-20     95.5     25     45GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
92Q800A0    397   CATE_LITCT Cathepsin E OS=Lithobates catesbei...3505e-20     95.5     26     44GO:0005768; C:endosome; ISS:UniProtKB.
GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB.
GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
93O60020    405   ASPR1_PHARH Aspartic protease OS=Phaffia rhod...3777e-20     95.1     27     45GO:0005576; C:extracellular region; IDA:UniProtKB.
GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB.
GO:0006508; P:proteolysis; IDA:UniProtKB.
94Q4WZS3    428   Y5950_ASPFU Putative aspergillopepsin A-like ...3633e-19     93.6     28     43GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
95Q05744    398   CATD_CHICK Cathepsin D OS=Gallus gallus (Chic...3537e-19     92     27     43GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
96P43159    396   CATE_RABIT Cathepsin E OS=Oryctolagus cunicul...4019e-19     91.7     28     44GO:0005768; C:endosome; ISS:UniProtKB.
GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB.
GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
97P07339    412   CATD_HUMAN Cathepsin D OS=Homo sapiens (Human...3503e-18     90.5     27     42GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; TAS:ProtInc.
GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
98Q03168    387   ASPP_AEDAE Lysosomal aspartic protease OS=Aed...3464e-18     89.7     27     43GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
99Q9TSZ1    400   RENI_CALJA Renin OS=Callithrix jacchus (White...3575e-18     89.7     27     44GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
100P00799    430   CARP_RHIMI Mucorpepsin OS=Rhizomucor miehei. ...3497e-18     89.4     26     42
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
101O76856    383   CATD_DICDI Cathepsin D OS=Dictyostelium disco...3579e-18     88.6     27     43GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0005764; C:lysosome; IDA:dictyBase.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
102Q03699    391   CARP3_RHINI Rhizopuspepsin-3 OS=Rhizopus nive...4259e-18     88.6     26     41
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
103O93428    396   CATD_CHIHA Cathepsin D OS=rhinoceratus hamatu...4331e-17     88.6     25     42GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB.
GO:0006508; P:proteolysis; IDA:UniProtKB.
104P18242    410   CATD_MOUSE Cathepsin D OS=Mus musculus (Mouse...3631e-17     88.6     26     41GO:0005764; C:lysosome; IDA:MGI.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:MGI.
GO:0004190; F:aspartic-type endopeptidase activity; IDA:MGI.
GO:0000045; P:autophagic vacuole assembly; IMP:MGI.::GO:0006508; P:proteolysis; IC:MGI.
105P81214    395   CARP_SYNRA Syncephapepsin OS=Syncephalastrum ...3422e-17     88.2     27     45
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
106O01530    389   ASP6_CAEEL Aspartic protease 6 OS=Caenorhabdi...3522e-17     87.8     25     44GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0008219; P:cell death; IMP:WormBase.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
107P55956    398   ASP3_CAEEL Aspartic protease 3 OS=Caenorhabdi...3602e-17     87.8     26     41GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0008219; P:cell death; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
108P60016    406   RENI_PANTR Renin OS=Pan troglodytes (Chimpanz...3573e-17     87.4     26     43GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
109P00797    406   RENI_HUMAN Renin OS=Homo sapiens (Human). GN=...3573e-17     87.4     26     43GO:0005615; C:extracellular space; IDA:HGNC.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IDA:HGNC.
GO:0002003; P:angiotensin maturation; IDA:HGNC.::GO:0006508; P:proteolysis; IDA:HGNC.::GO:0043408; P:regulation of MAPK cascade; IDA:HGNC.
110D4AZK1    509   CTSD_ARTBC Probable aspartic-type endopeptida...4573e-17     87.8     25     39GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
111P06281    402   RENI1_MOUSE Renin-1 OS=Mus musculus (Mouse). ...3544e-17     87     25     43GO:0005615; C:extracellular space; IDA:MGI.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0002003; P:angiotensin maturation; IMP:MGI.::GO:0048469; P:cell maturation; IMP:MGI.::GO:0042756; P:drinking behavior; IMP:MGI.::GO:0009755; P:hormone-mediated signaling pathway; IDA:MGI.::GO:0008584; P:male gonad development; IEP:UniProtKB.::GO:0001823; P:mesonephros development; IEP:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0002018; P:renin-angiotensin regulation of aldosterone production; IDA:MGI.
112P08424    402   RENI_RAT Renin OS=Rattus norvegicus (Rat). GN...3864e-17     86.7     25     42GO:0044444; C:cytoplasmic part; IDA:RGD.::GO:0005615; C:extracellular space; IDA:RGD.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.::GO:0005159; F:insulin-like growth factor receptor binding; IDA:RGD.
GO:0002003; P:angiotensin maturation; IDA:RGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0051591; P:response to cAMP; IDA:RGD.::GO:0070305; P:response to cGMP; IDA:RGD.::GO:0042493; P:response to drug; IDA:RGD.::GO:0006950; P:response to stress; IDA:RGD.
113D4D8U6    509   CTSD_TRIVH Probable aspartic-type endopeptida...4646e-17     87     25     39GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
114Q6DLS0    406   RENI_MACFA Renin OS=Macaca fascicularis (Crab...3576e-17     86.3     26     43GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
115Q6DLW5    406   RENI_MACMU Renin OS=Macaca mulatta (Rhesus ma...3566e-17     86.3     26     43GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
116Q06325    596   YPS7_YEAST Aspartic proteinase yapsin-7 OS=Sa...4199e-17     86.7     26     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
117Q9DEX3    396   CATD_CLUHA Cathepsin D OS=Clupea harengus (At...3523e-16     84.3     25     43GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
118Q6DYE7    403   RENI_CANFA Renin OS=Canis familiaris (Dog) (C...3556e-16     83.6     25     43GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
119P56272    324   PEP2B_GADMO Pepsin-2B OS=Gadus morhua (Atlant...3500.000000000000001     81.6     25     42
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
120P00796    401   RENI2_MOUSE Renin-2 OS=Mus musculus (Mouse). ...3540.000000000000001     82.4     24     42GO:0005615; C:extracellular space; IDA:MGI.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0045777; P:positive regulation of blood pressure; IDA:MGI.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
121C5FEK4    377   CTSD_ARTOC Probable aspartic-type endopeptida...3360.000000000000001     82     27     41GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
records
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