rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | P27821 | 387 | PEPA2_RABIT Pepsin II-2/3 OS=Oryctolagus cuni... | 341 | 4e-20 | 95.5 | 25 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 92 | Q800A0 | 397 | CATE_LITCT Cathepsin E OS=Lithobates catesbei... | 350 | 5e-20 | 95.5 | 26 | 44 | GO:0005768; C:endosome; ISS:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 93 | O60020 | 405 | ASPR1_PHARH Aspartic protease OS=Phaffia rhod... | 377 | 7e-20 | 95.1 | 27 | 45 | GO:0005576; C:extracellular region; IDA:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006508; P:proteolysis; IDA:UniProtKB. | 94 | Q4WZS3 | 428 | Y5950_ASPFU Putative aspergillopepsin A-like ... | 363 | 3e-19 | 93.6 | 28 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 95 | Q05744 | 398 | CATD_CHICK Cathepsin D OS=Gallus gallus (Chic... | 353 | 7e-19 | 92 | 27 | 43 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 96 | P43159 | 396 | CATE_RABIT Cathepsin E OS=Oryctolagus cunicul... | 401 | 9e-19 | 91.7 | 28 | 44 | GO:0005768; C:endosome; ISS:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 97 | P07339 | 412 | CATD_HUMAN Cathepsin D OS=Homo sapiens (Human... | 350 | 3e-18 | 90.5 | 27 | 42 | GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; TAS:ProtInc. | | | | | | | | | | GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 98 | Q03168 | 387 | ASPP_AEDAE Lysosomal aspartic protease OS=Aed... | 346 | 4e-18 | 89.7 | 27 | 43 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 99 | Q9TSZ1 | 400 | RENI_CALJA Renin OS=Callithrix jacchus (White... | 357 | 5e-18 | 89.7 | 27 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 100 | P00799 | 430 | CARP_RHIMI Mucorpepsin OS=Rhizomucor miehei. ... | 349 | 7e-18 | 89.4 | 26 | 42 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 101 | O76856 | 383 | CATD_DICDI Cathepsin D OS=Dictyostelium disco... | 357 | 9e-18 | 88.6 | 27 | 43 | GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0005764; C:lysosome; IDA:dictyBase. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 102 | Q03699 | 391 | CARP3_RHINI Rhizopuspepsin-3 OS=Rhizopus nive... | 425 | 9e-18 | 88.6 | 26 | 41 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 103 | O93428 | 396 | CATD_CHIHA Cathepsin D OS=rhinoceratus hamatu... | 433 | 1e-17 | 88.6 | 25 | 42 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006508; P:proteolysis; IDA:UniProtKB. | 104 | P18242 | 410 | CATD_MOUSE Cathepsin D OS=Mus musculus (Mouse... | 363 | 1e-17 | 88.6 | 26 | 41 | GO:0005764; C:lysosome; IDA:MGI.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:MGI. | | | | | | | | | | GO:0000045; P:autophagic vacuole assembly; IMP:MGI.::GO:0006508; P:proteolysis; IC:MGI. | 105 | P81214 | 395 | CARP_SYNRA Syncephapepsin OS=Syncephalastrum ... | 342 | 2e-17 | 88.2 | 27 | 45 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 106 | O01530 | 389 | ASP6_CAEEL Aspartic protease 6 OS=Caenorhabdi... | 352 | 2e-17 | 87.8 | 25 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008219; P:cell death; IMP:WormBase.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 107 | P55956 | 398 | ASP3_CAEEL Aspartic protease 3 OS=Caenorhabdi... | 360 | 2e-17 | 87.8 | 26 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008219; P:cell death; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 108 | P60016 | 406 | RENI_PANTR Renin OS=Pan troglodytes (Chimpanz... | 357 | 3e-17 | 87.4 | 26 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 109 | P00797 | 406 | RENI_HUMAN Renin OS=Homo sapiens (Human). GN=... | 357 | 3e-17 | 87.4 | 26 | 43 | GO:0005615; C:extracellular space; IDA:HGNC.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:HGNC. | | | | | | | | | | GO:0002003; P:angiotensin maturation; IDA:HGNC.::GO:0006508; P:proteolysis; IDA:HGNC.::GO:0043408; P:regulation of MAPK cascade; IDA:HGNC. | 110 | D4AZK1 | 509 | CTSD_ARTBC Probable aspartic-type endopeptida... | 457 | 3e-17 | 87.8 | 25 | 39 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 111 | P06281 | 402 | RENI1_MOUSE Renin-1 OS=Mus musculus (Mouse). ... | 354 | 4e-17 | 87 | 25 | 43 | GO:0005615; C:extracellular space; IDA:MGI.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0002003; P:angiotensin maturation; IMP:MGI.::GO:0048469; P:cell maturation; IMP:MGI.::GO:0042756; P:drinking behavior; IMP:MGI.::GO:0009755; P:hormone-mediated signaling pathway; IDA:MGI.::GO:0008584; P:male gonad development; IEP:UniProtKB.::GO:0001823; P:mesonephros development; IEP:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0002018; P:renin-angiotensin regulation of aldosterone production; IDA:MGI. | 112 | P08424 | 402 | RENI_RAT Renin OS=Rattus norvegicus (Rat). GN... | 386 | 4e-17 | 86.7 | 25 | 42 | GO:0044444; C:cytoplasmic part; IDA:RGD.::GO:0005615; C:extracellular space; IDA:RGD.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.::GO:0005159; F:insulin-like growth factor receptor binding; IDA:RGD. | | | | | | | | | | GO:0002003; P:angiotensin maturation; IDA:RGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0051591; P:response to cAMP; IDA:RGD.::GO:0070305; P:response to cGMP; IDA:RGD.::GO:0042493; P:response to drug; IDA:RGD.::GO:0006950; P:response to stress; IDA:RGD. | 113 | D4D8U6 | 509 | CTSD_TRIVH Probable aspartic-type endopeptida... | 464 | 6e-17 | 87 | 25 | 39 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 114 | Q6DLS0 | 406 | RENI_MACFA Renin OS=Macaca fascicularis (Crab... | 357 | 6e-17 | 86.3 | 26 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 115 | Q6DLW5 | 406 | RENI_MACMU Renin OS=Macaca mulatta (Rhesus ma... | 356 | 6e-17 | 86.3 | 26 | 43 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 116 | Q06325 | 596 | YPS7_YEAST Aspartic proteinase yapsin-7 OS=Sa... | 419 | 9e-17 | 86.7 | 26 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 117 | Q9DEX3 | 396 | CATD_CLUHA Cathepsin D OS=Clupea harengus (At... | 352 | 3e-16 | 84.3 | 25 | 43 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 118 | Q6DYE7 | 403 | RENI_CANFA Renin OS=Canis familiaris (Dog) (C... | 355 | 6e-16 | 83.6 | 25 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 119 | P56272 | 324 | PEP2B_GADMO Pepsin-2B OS=Gadus morhua (Atlant... | 350 | 0.000000000000001 | 81.6 | 25 | 42 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 120 | P00796 | 401 | RENI2_MOUSE Renin-2 OS=Mus musculus (Mouse). ... | 354 | 0.000000000000001 | 82.4 | 24 | 42 | GO:0005615; C:extracellular space; IDA:MGI. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045777; P:positive regulation of blood pressure; IDA:MGI.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 121 | C5FEK4 | 377 | CTSD_ARTOC Probable aspartic-type endopeptida... | 336 | 0.000000000000001 | 82 | 27 | 41 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. |