rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
121 | P07339 | 412 | CATD_HUMAN Cathepsin D OS=Homo sapiens (Human... | 416 | 0.00000003 | 59.7 | 23 | 37 | GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; TAS:ProtInc. | | | | | | | | | | GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 122 | P18242 | 410 | CATD_MOUSE Cathepsin D OS=Mus musculus (Mouse... | 27 | 0.091 | 39.3 | 59 | 78 | GO:0005764; C:lysosome; IDA:MGI.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:MGI. | | | | | | | | | | GO:0000045; P:autophagic vacuole assembly; IMP:MGI.::GO:0006508; P:proteolysis; IC:MGI. | 123 | P00796 | 401 | RENI2_MOUSE Renin-2 OS=Mus musculus (Mouse). ... | 85 | 0.34 | 37.4 | 31 | 49 | GO:0005615; C:extracellular space; IDA:MGI. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045777; P:positive regulation of blood pressure; IDA:MGI.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 124 | Q4LAL9 | 410 | CATD_CANFA Cathepsin D OS=Canis familiaris (D... | 337 | 0.00000004 | 59.3 | 25 | 40 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 125 | P14091 | 401 | CATE_HUMAN Cathepsin E OS=Homo sapiens (Human... | 317 | 0.00000004 | 58.9 | 24 | 40 | GO:0005768; C:endosome; IDA:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB. | | | | | | | | | | GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; IDA:UniProtKB.::GO:0007586; P:digestion; TAS:ProtInc.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 126 | Q6DYE7 | 403 | RENI_CANFA Renin OS=Canis familiaris (Dog) (C... | 66 | 0.38 | 37 | 29 | 55 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 127 | Q9XFX4 | 506 | CARDB_CYNCA Procardosin-B OS=Cynara carduncul... | 238 | 0.00000006 | 58.9 | 25 | 45 | GO:0005618; C:cell wall; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0000326; C:protein storage vacuole; IEA:UniProtKB-SubCell.::GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006629; P:lipid metabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 128 | B6HL60 | 396 | PEPA_PENCW Aspartic protease pep1 OS=54-1255)... | 294 | 0.00000008 | 58.5 | 28 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 129 | Q01972 | 397 | PEPA_PENRO Aspartic protease pep1 OS=Penicill... | 337 | 0.00000008 | 58.2 | 27 | 43 | GO:0005576; C:extracellular region; IDA:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0060359; P:response to ammonium ion; IDA:UniProtKB.::GO:0009268; P:response to pH; IDA:UniProtKB. | 130 | P43159 | 396 | CATE_RABIT Cathepsin E OS=Oryctolagus cunicul... | 311 | 0.00000009 | 58.2 | 23 | 41 | GO:0005768; C:endosome; ISS:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 131 | P53057 | 165 | YPS5_YEAST Yapsin-5 OS=Saccharomyces cerevisi... | 91 | 0.00000009 | 55.8 | 40 | 55 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 132 | P40782 | 473 | CYPR1_CYNCA Cyprosin OS=Cynara cardunculus (C... | 99 | 0.62 | 36.6 | 30 | 43 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006629; P:lipid metabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 133 | E5A7T3 | 409 | PEPA_LEPMJ Aspartic protease PEP1 OS=Av1-4-5-... | 283 | 0.0000001 | 57.4 | 29 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 134 | C5FEK4 | 377 | CTSD_ARTOC Probable aspartic-type endopeptida... | 309 | 0.0000002 | 57 | 23 | 39 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 135 | O13340 | 425 | CARP_PODAS Podosporapepsin OS=Podospora anser... | 67 | 0.012 | 42 | 31 | 54 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 136 | D4AZK1 | 509 | CTSD_ARTBC Probable aspartic-type endopeptida... | 52 | 0.43 | 37 | 37 | 58 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 137 | P80209 | 390 | CATD_BOVIN Cathepsin D OS=Bos taurus (Bovine)... | 424 | 0.0000002 | 56.6 | 23 | 37 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 138 | D4D8U6 | 509 | CTSD_TRIVH Probable aspartic-type endopeptida... | 52 | 0.48 | 37 | 37 | 58 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 139 | Q9XFX3 | 504 | CARDA_CYNCA Procardosin-A OS=Cynara carduncul... | 63 | 0.064 | 39.7 | 38 | 59 | GO:0005618; C:cell wall; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0000326; C:protein storage vacuole; IEA:UniProtKB-SubCell.::GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006629; P:lipid metabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 140 | P55956 | 398 | ASP3_CAEEL Aspartic protease 3 OS=Caenorhabdi... | 52 | 0.008 | 42.4 | 37 | 58 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008219; P:cell death; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 141 | A2R3L3 | 394 | PEPA_ASPNC Aspartic protease pep1 OS=Aspergil... | 321 | 0.0000004 | 56.2 | 26 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 142 | P17576 | 340 | CARP_IRPLA Polyporopepsin OS=Irpex lacteus (M... | 84 | 0.048 | 40 | 33 | 52 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 143 | P00799 | 430 | CARP_RHIMI Mucorpepsin OS=Rhizomucor miehei. ... | 27 | 1.3 | 35.4 | 48 | 74 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 144 | Q800A0 | 397 | CATE_LITCT Cathepsin E OS=Lithobates catesbei... | 336 | 0.0000006 | 55.5 | 24 | 41 | GO:0005768; C:endosome; ISS:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 145 | P78735 | 394 | PEPA_PENJA Aspartic protease pepA OS=Penicill... | 282 | 0.0000008 | 55.1 | 28 | 43 | GO:0005576; C:extracellular region; IDA:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 146 | Q12567 | 394 | PEPA_ASPSA Aspartic protease pep1 OS=Aspergil... | 321 | 0.000001 | 54.7 | 26 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 147 | Q9HEZ3 | 394 | PEPB_PENJA Aspartic protease pepB OS=Penicill... | 288 | 0.000001 | 54.7 | 26 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 148 | P55325 | 394 | PEPA_ASPNG Aspartic protease pep1 OS=Aspergil... | 321 | 0.000001 | 54.3 | 26 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 149 | Q4WFS2 | 439 | Y1220_ASPFU Probable aspartic-type endopeptid... | 294 | 0.000002 | 54.3 | 27 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 150 | P46925 | 453 | PLM2_PLAFA Plasmepsin-2 OS=Plasmodium falcipa... | 328 | 0.000002 | 53.9 | 24 | 42 | GO:0005773; C:vacuole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 151 | A1DDK1 | 395 | PEPA_NEOFI Aspartic protease pep1 OS=181) (As... | 290 | 0.000002 | 53.9 | 27 | 42 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. |