UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YLR117C

Length:

687

Number of sequences:

5887

Description:

YLR117C CLF1 SGDID:S000004107, Chr XII from 384534-382471, Genome Release 64-1-1, reverse complement, Verified ORF, "Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; homolog of Drosophila crooked neck protein; interacts with U1 snRNP proteins"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	Q12309	687	CLF1_YEAST Pre-mRNA-splicing factor CLF1 OS=S...	687	0	1404	100	100	GO:0000785; C:chromatin; IDA:SGD.::GO:0000974; C:Prp19 complex; IDA:SGD.::GO:0071006; C:U2-type catalytic step 1 spliceosome; IDA:SGD.::GO:0071007; C:U2-type catalytic step 2 spliceosome; IDA:SGD.::GO:0071008; C:U2-type post-mRNA release spliceosomal complex; IDA:SGD.::GO:0071004; C:U2-type prespliceosome; IDA:SGD.
									GO:0003682; F:chromatin binding; IDA:SGD.::GO:0003688; F:DNA replication origin binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000354; P:cis assembly of pre-catalytic spliceosome; IMP:SGD.::GO:0006270; P:DNA-dependent DNA replication initiation; IMP:SGD.
2	Q6CJK2	684	CLF1_KLULA Pre-mRNA-splicing factor CLF1 OS=1...	679	0	682	49	71	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005488; F:binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
3	Q750X3	683	CLF1_ASHGO Pre-mRNA-splicing factor CLF1 OS=Y...	686	0	681	49	68	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005488; F:binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
4	Q6FW76	695	CLF1_CANGA Pre-mRNA-splicing factor CLF1 OS=N...	683	0	645	47	66	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005488; F:binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
5	Q6C186	676	CLF1_YARLI Pre-mRNA-splicing factor CLF1 OS=l...	683	9e-172	514	42	61	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005488; F:binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
6	Q5BDX1	673	CLF1_EMENI Pre-mRNA-splicing factor clf1 OS=1...	684	5e-168	504	40	62	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005488; F:binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
7	Q5K654	677	CLF1_PARBR Pre-mRNA-splicing factor CLF1 OS=P...	679	3e-167	503	41	62	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005488; F:binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
8	P87312	674	CLF1_SCHPO Pre-mRNA-splicing factor cwf4 OS=S...	682	9e-166	499	40	61	GO:0005681; C:spliceosomal complex; IDA:PomBase.
									GO:0005515; F:protein binding; IPI:IntAct.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; IC:PomBase.
9	Q4WT84	676	CLF1_ASPFU Pre-mRNA-splicing factor clf1 OS=A...	676	5e-161	486	39	62	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005488; F:binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
10	Q5AED6	758	CLF1_CANAL Pre-mRNA-splicing factor CLF1 OS=C...	709	7e-153	468	38	61	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005488; F:binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
11	Q527H0	691	CLF1_MAGO7 Pre-mRNA-splicing factor CLF1 OS=b...	661	8e-149	456	38	59	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005488; F:binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
12	P63155	690	CRNL1_RAT Crooked neck-like protein 1 OS=Ratt...	691	3e-146	449	38	59
									GO:0003723; F:RNA binding; ISS:UniProtKB.
									GO:0000245; P:spliceosomal complex assembly; ISS:UniProtKB.
13	P63154	690	CRNL1_MOUSE Crooked neck-like protein 1 OS=Mu...	691	3e-146	449	38	59	GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; ISS:UniProtKB.
									GO:0003723; F:RNA binding; ISS:UniProtKB.
									GO:0000245; P:spliceosomal complex assembly; ISS:UniProtKB.
14	Q6BSP7	714	CLF1_DEBHA Pre-mRNA-splicing factor CLF1 OS=0...	713	7e-146	449	37	60	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005488; F:binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
15	Q9BZJ0	848	CRNL1_HUMAN Crooked neck-like protein 1 OS=Ho...	691	1e-144	449	38	59	GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
									GO:0003723; F:RNA binding; IDA:UniProtKB.
									GO:0000245; P:spliceosomal complex assembly; IDA:UniProtKB.
16	Q7SGD2	695	CLF1_NEUCR Pre-mRNA-splicing factor clf-1 OS=...	678	5e-143	441	38	59	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005488; F:binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
17	P17886	702	CRN_DROME Protein crooked neck OS=Drosophila ...	690	3e-139	431	37	59	GO:0071013; C:catalytic step 2 spliceosome; IDA:FlyBase.::GO:0005813; C:centrosome; IDA:FlyBase.::GO:0072686; C:mitotic spindle; IDA:FlyBase.::GO:0016607; C:nuclear speck; IDA:FlyBase.::GO:0071011; C:precatalytic spliceosome; IDA:FlyBase.
									GO:0005488; F:binding; IEA:InterPro.
									GO:0008366; P:axon ensheathment; IMP:FlyBase.::GO:0051298; P:centrosome duplication; IMP:FlyBase.::GO:0008347; P:glial cell migration; IMP:FlyBase.::GO:0007443; P:Malpighian tubule morphogenesis; IMP:FlyBase.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; ISS:FlyBase.::GO:0007438; P:oenocyte development; IMP:FlyBase.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; IMP:FlyBase.
18	Q4PB37	781	CLF1_USTMA Pre-mRNA-splicing factor CLF1 OS=U...	705	2e-138	432	36	57	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005488; F:binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
19	P0CO10	726	CLF1_CRYNJ Pre-mRNA-splicing factor CLF1 OS=A...	687	5e-135	421	36	56	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005488; F:binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
20	P0CO11	726	CLF1_CRYNB Pre-mRNA-splicing factor CLF1 OS=(...	687	5e-135	421	36	56	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005488; F:binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
21	Q9HF03	724	CLF1_CRYNV Pre-mRNA-splicing factor CLF1 OS=g...	687	1e-134	420	36	56	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005488; F:binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
22	Q54XP4	705	CRNL1_DICDI Crooked neck-like protein 1 OS=Di...	689	2e-121	385	36	56	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; ISS:UniProtKB.
									GO:0003723; F:RNA binding; ISS:UniProtKB.
									GO:0000245; P:spliceosomal complex assembly; ISS:UniProtKB.
23	Q5BH69	851	SYF1_EMENI Pre-mRNA-splicing factor syf1 OS=1...	113	3.1	34.7	26	46	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005488; F:binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
24	Q99PK0	855	SYF1_RAT Pre-mRNA-splicing factor SYF1 OS=Rat...	196	0.92	36.6	22	41
									GO:0005488; F:binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; ISS:UniProtKB.::GO:0006283; P:transcription-coupled nucleotide-excision repair; ISS:UniProtKB.
25	Q9DCD2	855	SYF1_MOUSE Pre-mRNA-splicing factor SYF1 OS=M...	196	0.91	36.6	22	41
									GO:0005488; F:binding; IEA:InterPro.
									GO:0001824; P:blastocyst development; IMP:MGI.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; ISS:UniProtKB.::GO:0006283; P:transcription-coupled nucleotide-excision repair; ISS:UniProtKB.
26	Q9HCS7	855	SYF1_HUMAN Pre-mRNA-splicing factor SYF1 OS=H...	196	2	35.4	22	41	GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
									GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IDA:UniProtKB.::GO:0006283; P:transcription-coupled nucleotide-excision repair; IDA:UniProtKB.
27	Q5REG1	981	SART3_PONAB Squamous cell carcinoma antigen r...	131	0.00002	51.6	31	51	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006396; P:RNA processing; IEA:InterPro.
28	Q15020	963	SART3_HUMAN Squamous cell carcinoma antigen r...	131	0.00002	51.6	31	51	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006396; P:RNA processing; IEA:InterPro.
29	Q4WVF4	839	SYF1_ASPFU Pre-mRNA-splicing factor syf1 OS=A...	146	4.6	34.3	25	42	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005488; F:binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
30	Q9P7R9	790	SYF1_SCHPO Pre-mRNA-splicing factor cwf3 OS=S...	148	2.3	35	28	45	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.::GO:0005681; C:spliceosomal complex; IDA:PomBase.
									GO:0005515; F:protein binding; IPI:IntAct.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; IC:PomBase.
31	Q54Z08	850	SYF1_DICDI Pre-mRNA-splicing factor SYF1 OS=D...	155	3.5	34.7	24	41	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005488; F:binding; IEA:InterPro.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.

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