UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YLR116W

Length:

476

Number of sequences:

5887

Description:

YLR116W MSL5 SGDID:S000004106, Chr XII from 380822-382252, Genome Release 64-1-1, Verified ORF, "Component of the commitment complex, which defines the first step in the splicing pathway; essential protein that interacts with Mud2p and Prp40p, forming a bridge between the intron ends; also involved in nuclear retention of pre-mRNA"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	Q12186	476	BBP_YEAST Branchpoint-bridging protein OS=Sac...	476	0	968	100	100	GO:0000243; C:commitment complex; IDA:SGD.
									GO:0045131; F:pre-mRNA branch point binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000398; P:nuclear mRNA splicing, via spliceosome; IPI:SGD.
2	Q6FW77	465	BBP_CANGA Branchpoint-bridging protein OS=NRR...	469	3e-137	410	51	65	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
3	Q750X2	507	BBP_ASHGO Branchpoint-bridging protein OS=Y-1...	282	9e-126	382	64	79	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
4	Q4WXV6	566	BBP_ASPFU Branchpoint-bridging protein OS=A11...	273	2e-96	308	55	72	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
5	Q8NIW7	607	BBP_NEUCR Branchpoint-bridging protein OS=125...	279	2e-96	309	54	71	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
6	O74555	587	BBP_SCHPO Branchpoint-bridging protein OS=Sch...	264	5e-93	300	55	70	GO:0000243; C:commitment complex; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000349; P:generation of catalytic spliceosome for first transesterification step; IDA:PomBase.
7	P0CO44	546	BBP_CRYNJ Branchpoint-bridging protein OS=ATC...	268	9e-85	277	50	71	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
8	P0CO45	546	BBP_CRYNB Branchpoint-bridging protein OS=(Fi...	268	9e-85	277	50	71	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
9	Q6C187	605	BBP_YARLI Branchpoint-bridging protein OS=lip...	273	1e-83	276	49	68	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
10	Q4P0H7	625	BBP_USTMA Branchpoint-bridging protein OS=Ust...	300	4e-79	264	45	63	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
11	Q6BSP4	518	BBP_DEBHA Branchpoint-bridging protein OS=008...	348	2e-70	238	42	55	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
12	Q5AED9	455	BBP_CANAL Branchpoint-bridging protein OS=Can...	280	1e-69	235	45	63	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
13	Q15637	639	SF01_HUMAN Splicing factor 1 OS=Homo sapiens ...	308	5e-68	235	43	61	GO:0005840; C:ribosome; NAS:UniProtKB.::GO:0005681; C:spliceosomal complex; IDA:HGNC.
									GO:0003723; F:RNA binding; TAS:UniProtKB.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000389; P:nuclear mRNA 3'-splice site recognition; TAS:HGNC.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
14	Q64213	653	SF01_MOUSE Splicing factor 1 OS=Mus musculus ...	304	2e-67	234	43	63	GO:0005737; C:cytoplasm; ISS:MGI.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0022402; P:cell cycle process; IGI:MGI.::GO:0033327; P:Leydig cell differentiation; IGI:MGI.::GO:0030238; P:male sex determination; IGI:MGI.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0050810; P:regulation of steroid biosynthetic process; IGI:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
15	Q54BM5	501	BBP_DICDI Branchpoint-bridging protein OS=Dic...	315	2e-51	187	39	55	GO:0000243; C:commitment complex; ISS:dictyBase.
									GO:0003723; F:RNA binding; ISS:dictyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000398; P:nuclear mRNA splicing, via spliceosome; ISS:dictyBase.
16	Q17339	463	GLD1_CAEEL Female germline-specific tumor sup...	166	1e-23	106	37	58	GO:0005829; C:cytosol; IDA:WormBase.
									GO:0003730; F:mRNA 3'-UTR binding; IDA:WormBase.::GO:0048027; F:mRNA 5'-UTR binding; IDA:WormBase.::GO:0003727; F:single-stranded RNA binding; IDA:WormBase.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0051729; P:germline cell cycle switching, mitotic to meiotic cell cycle; IMP:WormBase.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0017148; P:negative regulation of translation; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0048477; P:oogenesis; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0042127; P:regulation of cell proliferation; IMP:WormBase.::GO:0040020; P:regulation of meiosis; IMP:WormBase.
17	Q6IRN2	342	QKIB_XENLA Protein quaking-B OS=Xenopus laevi...	147	9e-23	102	36	58	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
18	Q32NN2	341	QKIA_XENLA Protein quaking-A OS=Xenopus laevi...	147	1e-22	102	36	58	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
19	Q9YH18	340	QKI_CHICK Protein quaking OS=Gallus gallus (C...	147	1e-22	102	37	58	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
20	Q6P104	319	QKIB_DANRE Protein quaking-B OS=Danio rerio (...	147	1e-22	101	36	58	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
21	Q5W9D5	341	QKI_PIG Protein quaking OS=Sus scrofa (Pig). ...	147	1e-22	102	36	58	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
22	Q9QYS9	341	QKI_MOUSE Protein quaking OS=Mus musculus (Mo...	147	1e-22	102	36	58	GO:0005737; C:cytoplasm; TAS:MGI.::GO:0005634; C:nucleus; TAS:MGI.
									GO:0003723; F:RNA binding; TAS:MGI.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
									GO:0042759; P:long-chain fatty acid biosynthetic process; IMP:MGI.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0042692; P:muscle cell differentiation; IMP:MGI.::GO:0042552; P:myelination; IMP:MGI.::GO:0010628; P:positive regulation of gene expression; IMP:MGI.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0007286; P:spermatid development; IGI:MGI.::GO:0001570; P:vasculogenesis; IMP:MGI.
23	Q96PU8	341	QKI_HUMAN Protein quaking OS=Homo sapiens (Hu...	147	1e-22	102	36	58	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
24	Q5W9D6	341	QKI_HORSE Protein quaking OS=Equus caballus (...	147	1e-22	102	36	58	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
25	Q7JJZ8	341	QKI_FELCA Protein quaking OS=Felis catus (Cat...	147	1e-22	102	36	58	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
26	Q9GMY1	341	QKI_CANFA Protein quaking OS=Canis familiaris...	147	1e-22	102	36	58	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
27	Q5W9D7	341	QKI_BOVIN Protein quaking OS=Bos taurus (Bovi...	147	1e-22	102	36	58	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
28	Q91XU1	341	QKI_RAT Protein quaking OS=Rattus norvegicus ...	147	1e-22	101	36	58	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
29	Q6P0D0	341	QKIA_DANRE Protein quaking-A OS=Danio rerio (...	138	3e-21	98.2	36	59	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
30	O01367	405	HOW_DROME Protein held out wings OS=Drosophil...	177	8e-21	97.8	34	58	GO:0005634; C:nucleus; IDA:UniProtKB.
									GO:0003730; F:mRNA 3'-UTR binding; IDA:FlyBase.
									GO:0007475; P:apposition of dorsal and ventral imaginal disc-derived wing surfaces; IMP:FlyBase.::GO:0008366; P:axon ensheathment; IMP:FlyBase.::GO:0007155; P:cell adhesion; IMP:UniProtKB.::GO:0030718; P:germ-line stem cell maintenance; IMP:FlyBase.::GO:0008347; P:glial cell migration; IMP:FlyBase.::GO:0008078; P:mesodermal cell migration; IMP:FlyBase.::GO:0016203; P:muscle attachment; IMP:UniProtKB.::GO:0007521; P:muscle cell fate determination; IDA:UniProtKB.::GO:0007438; P:oenocyte development; IMP:FlyBase.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; IMP:FlyBase.::GO:0008016; P:regulation of heart contraction; IMP:UniProtKB.::GO:0045214; P:sarcomere organization; IMP:FlyBase.::GO:0007525; P:somatic muscle development; IMP:FlyBase.::GO:0007284; P:spermatogonial cell division; IMP:FlyBase.
31	Q75GR5	281	SPIN1_ORYSJ KH domain-containing protein SPIN...	121	1e-20	95.1	44	60	GO:0005634; C:nucleus; IDA:UniProtKB.
									GO:0003677; F:DNA binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IDA:UniProtKB.
									GO:0009908; P:flower development; IEA:UniProtKB-KW.::GO:0048579; P:negative regulation of long-day photoperiodism, flowering; IMP:UniProtKB.::GO:0048577; P:negative regulation of short-day photoperiodism, flowering; IMP:UniProtKB.

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