Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR113W
Length:
435
Number of sequences:
5887
Description:
YLR113W HOG1 SGDID:S000004103, Chr XII from 371620-372927, Genome Release 64-1-1, Verified ORF, "Mitogen-activated protein kinase involved in osmoregulation; acts via three independent osmosensors; mitophagy-specific regulator; mediates the recruitment and activation of RNA Pol II at Hot1p-dependent promoters; localization regulated by Ptp2p and Ptp3p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
421P23293    657   BUR1_YEAST Serine/threonine-protein kinase BU...3362e-40     156     33     47GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IPI:SGD.::GO:0005634; C:nucleus; IPI:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:SGD.
GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IDA:SGD.::GO:0051571; P:positive regulation of histone H3-K4 methylation; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IDA:SGD.
422P20911    352   CDK7_XENLA Cyclin-dependent kinase 7 OS=Xenop...2974e-40     152     34     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
423Q07002    472   CDK18_HUMAN Cyclin-dependent kinase 18 OS=Hom...2844e-40     154     33     52
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0004871; F:signal transducer activity; NAS:UniProtKB.
424Q03957    528   CTK1_YEAST CTD kinase subunit alpha OS=Saccha...3046e-40     154     32     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:SGD.::GO:0005654; C:nucleoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0031124; P:mRNA 3'-end processing; IMP:SGD.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:SGD.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IMP:SGD.::GO:0032786; P:positive regulation of transcription elongation, DNA-dependent; IDA:SGD.::GO:0045943; P:positive regulation of transcription from RNA polymerase I promoter; IMP:SGD.::GO:0045903; P:positive regulation of translational fidelity; IMP:SGD.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006412; P:translation; IEA:UniProtKB-KW.
425Q6GLD8    376   CDK9_XENTR Cyclin-dependent kinase 9 OS=Xenop...3047e-40     151     33     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
426Q5ZKN1    372   CDK9_CHICK Cyclin-dependent kinase 9 OS=Gallu...3008e-40     151     33     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
427Q5EAB2    372   CDK9_BOVIN Cyclin-dependent kinase 9 OS=Bos t...3111e-39     151     33     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
428P21965    375   MCK1_YEAST Protein kinase MCK1 OS=Saccharomyc...3052e-39     150     33     53GO:0005625; C:soluble fraction; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IDA:SGD.
GO:0030437; P:ascospore formation; IMP:SGD.::GO:0006303; P:double-strand break repair via nonhomologous end joining; IMP:SGD.::GO:0007126; P:meiosis; IMP:SGD.::GO:0000070; P:mitotic sister chromatid segregation; IGI:SGD.
429Q8SQW2    329   CTK1_ENCCU Probable CTD kinase subunit alpha ...2882e-39     149     34     51GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
430Q2QSL4    327   CDKF2_ORYSJ Putative cyclin-dependent kinase ...3042e-39     149     33     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
431P50750    372   CDK9_HUMAN Cyclin-dependent kinase 9 OS=Homo ...3122e-39     150     33     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IDA:UniProtKB.::GO:0008023; C:transcription elongation factor complex; TAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:UniProtKB.
GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0071345; P:cellular response to cytokine stimulus; IDA:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0071157; P:negative regulation of cell cycle arrest; IDA:UniProtKB.::GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.::GO:0006282; P:regulation of DNA repair; IDA:UniProtKB.::GO:0031056; P:regulation of histone modification; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0043111; P:replication fork arrest; IDA:UniProtKB.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:ProtInc.::GO:0016032; P:viral reproduction; TAS:Reactome.
432Q641Z4    372   CDK9_RAT Cyclin-dependent kinase 9 OS=Rattus ...3113e-39     150     33     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
433Q99J95    372   CDK9_MOUSE Cyclin-dependent kinase 9 OS=Mus m...3113e-39     150     33     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0008024; C:positive transcription elongation factor complex b; TAS:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.::GO:0017069; F:snRNA binding; IDA:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
434Q38775    312   CDC2D_ANTMA Cell division control protein 2 h...2935e-39     148     33     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
435O74456    288   PEF1_SCHPO Serine/threonine-protein kinase pe...2999e-39     146     35     50GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; IGI:PomBase.::GO:0007165; P:signal transduction; IC:PomBase.::GO:0007089; P:traversing start control point of mitotic cell cycle; IGI:PomBase.
436Q4V862    376   CDK9A_XENLA Cyclin-dependent kinase 9-A OS=Xe...3001e-38     148     32     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
437Q96WV9    591   CDK9_SCHPO Probable cyclin-dependent kinase 9...3102e-38     150     31     50GO:0070693; C:P-TEFb-cap methyltransferase complex; IDA:PomBase.::GO:0008024; C:positive transcription elongation factor complex b; NAS:PomBase.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:PomBase.
GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IMP:PomBase.::GO:0034243; P:regulation of transcription elongation from RNA polymerase II promoter; IMP:PomBase.::GO:0006360; P:transcription from RNA polymerase I promoter; IGI:PomBase.
438P06242    306   KIN28_YEAST Serine/threonine-protein kinase K...3023e-38     145     32     52GO:0070985; C:TFIIK complex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:SGD.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IDA:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:SGD.::GO:0006360; P:transcription from RNA polymerase I promoter; IMP:SGD.::GO:0006366; P:transcription from RNA polymerase II promoter; IDA:SGD.
439Q8SRI3    334   MRK1_ENCCU Probable serine/threonine-protein ...3034e-38     145     32     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
440Q8IVW4    592   CDKL3_HUMAN Cyclin-dependent kinase-like 3 OS...2852e-37     147     35     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
441Q4R8T9    590   CDKL3_MACFA Cyclin-dependent kinase-like 3 OS...2852e-37     147     35     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
442P51953    344   CDK7_CARAU Cyclin-dependent kinase 7 OS=Caras...2982e-37     144     34     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
443Q12222    375   YGK3_YEAST Glycogen synthase kinase-3 homolog...2933e-37     144     32     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IGI:SGD.
GO:0006508; P:proteolysis; IGI:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IGI:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
444Q6FQ83    667   BUR1_CANGA Serine/threonine-protein kinase BU...3403e-37     147     30     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
445Q9JM01    593   CDKL3_RAT Cyclin-dependent kinase-like 3 OS=R...2854e-37     146     34     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
446Q8BLF2    595   CDKL3_MOUSE Cyclin-dependent kinase-like 3 OS...2857e-37     145     34     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
447Q09437    719   YP62_CAEEL Putative serine/threonine-protein ...2971e-36     146     34     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006974; P:response to DNA damage stimulus; IMP:WormBase.
448B5DE93    1239   CDK12_XENTR Cyclin-dependent kinase 12 OS=Xen...2881e-36     148     33     51GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; ISS:UniProtKB.::GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB.::GO:0008380; P:RNA splicing; ISS:UniProtKB.
449Q6C842    706   BUR1_YARLI Serine/threonine-protein kinase BU...2452e-36     145     35     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
450Q9VPC0    952   KP58_DROME Serine/threonine-protein kinase PI...2942e-36     146     31     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0007155; P:cell adhesion; IMP:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.
451Q9NR20    520   DYRK4_HUMAN Dual specificity tyrosine-phospho...3064e-36     143     31     52GO:0005794; C:Golgi apparatus; IDA:HPA.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
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