Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR106C
Length:
4910
Number of sequences:
5887
Description:
YLR106C MDN1 SGDID:S000004096, Chr XII from 363738-349006, Genome Release 64-1-1, reverse complement, Verified ORF, "Huge dynein-related AAA-type ATPase (midasin), forms extended pre-60S particle with the Rix1 complex (Rix1p-Ipi1p-Ipi3p); acts in removal of ribosomal biogenesis factors at successive steps of pre-60S assembly and export from nucleus"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31B0R0T1    1896   K0564_DANRE Uncharacterized protein KIAA0564 ...913.7     37.7     26     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.
32P11047    1609   LAMC1_HUMAN Laminin subunit gamma-1 OS=Homo s...4880.00008     53.1     20     38GO:0005615; C:extracellular space; NAS:UniProtKB.::GO:0005606; C:laminin-1 complex; NAS:UniProtKB.::GO:0043259; C:laminin-10 complex; TAS:BHF-UCL.::GO:0043260; C:laminin-11 complex; TAS:BHF-UCL.
GO:0005201; F:extracellular matrix structural constituent; IMP:HGNC.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0016477; P:cell migration; IMP:HGNC.::GO:0007492; P:endoderm development; TAS:ProtInc.::GO:0022617; P:extracellular matrix disassembly; IMP:HGNC.::GO:0031581; P:hemidesmosome assembly; IMP:HGNC.::GO:0050679; P:positive regulation of epithelial cell proliferation; TAS:HGNC.::GO:0006461; P:protein complex assembly; IDA:HGNC.::GO:0034446; P:substrate adhesion-dependent cell spreading; IDA:BHF-UCL.
33P37276    4639   DYHC_DROME Dynein heavy chain, cytoplasmic OS...1151.8     38.9     23     45GO:0005938; C:cell cortex; IDA:FlyBase.::GO:0030286; C:dynein complex; IPI:FlyBase.::GO:0045169; C:fusome; TAS:FlyBase.::GO:0045172; C:germline ring canal; TAS:FlyBase.::GO:0005794; C:Golgi apparatus; IDA:FlyBase.::GO:0000776; C:kinetochore; IDA:FlyBase.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0030529; C:ribonucleoprotein complex; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042623; F:ATPase activity, coupled; IDA:FlyBase.::GO:0003777; F:microtubule motor activity; IDA:FlyBase.
GO:0008088; P:axon cargo transport; IMP:FlyBase.::GO:0007098; P:centrosome cycle; IMP:FlyBase.::GO:0051642; P:centrosome localization; IMP:FlyBase.::GO:0040003; P:chitin-based cuticle development; IGI:FlyBase.::GO:0007282; P:cystoblast division; IMP:FlyBase.::GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0045198; P:establishment of epithelial cell apical/basal polarity; IDA:FlyBase.::GO:0051683; P:establishment of Golgi localization; IMP:FlyBase.::GO:0040001; P:establishment of mitotic spindle localization; TAS:FlyBase.::GO:0007301; P:female germline ring canal formation; TAS:FlyBase.::GO:0048134; P:germ-line cyst formation; TAS:FlyBase.::GO:0007294; P:germarium-derived oocyte fate determination; IMP:FlyBase.::GO:0008298; P:intracellular mRNA localization; TAS:FlyBase.::GO:0006886; P:intracellular protein transport; IMP:FlyBase.::GO:0051237; P:maintenance of RNA location; IDA:FlyBase.::GO:0048311; P:mitochondrion distribution; IMP:FlyBase.::GO:0047497; P:mitochondrion transport along microtubule; IMP:FlyBase.::GO:0007067; P:mitosis; IMP:FlyBase.::GO:0007052; P:mitotic spindle organization; IMP:FlyBase.::GO:0043148; P:mitotic spindle stabilization; IMP:FlyBase.::GO:0016319; P:mushroom body development; IMP:FlyBase.::GO:0007405; P:neuroblast proliferation; IMP:FlyBase.::GO:0007312; P:oocyte nucleus migration involved in oocyte dorsal/ventral axis specification; TAS:FlyBase.::GO:0030723; P:ovarian fusome organization; IMP:FlyBase.::GO:0007279; P:pole cell formation; IMP:FlyBase.::GO:0046604; P:positive regulation of mitotic centrosome separation; IMP:FlyBase.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IMP:FlyBase.::GO:0050658; P:RNA transport; IMP:FlyBase.::GO:0034063; P:stress granule assembly; IMP:BHF-UCL.
34P0C6U5    4421   R1A_CVHN5 Replicase polyprotein 1a OS=Human c...1580.0001     52.8     25     49GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro.
GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro.
35P55150    335   GVPN_ANAFL Gas vesicle protein GvpN OS=Anabae...3000.33     40.4     21     39GO:0031411; C:gas vesicle; IEA:UniProtKB-SubCell.::GO:0005773; C:vacuole; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.
GO:0031412; P:gas vesicle organization; IEA:InterPro.
36P0C6X4    7132   R1AB_CVHN5 Replicase polyprotein 1ab OS=Human...1580.0002     52     25     49GO:0044172; C:host cell endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.::GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro.
37Q8CC88    1905   K0564_MOUSE Uncharacterized protein KIAA0564 ...6631.6     38.9     19     35GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.
38P94474    320   YEAC_BACSU Uncharacterized protein yeaC OS=Ba...1380.0002     50.8     30     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.
39A8MU46    457   SMTL1_HUMAN Smoothelin-like protein 1 OS=Homo...2150.3     40.8     26     38GO:0031674; C:I band; IEA:UniProtKB-SubCell.::GO:0031430; C:M band; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
GO:0045908; P:negative regulation of vasodilation; ISS:UniProtKB.::GO:0045907; P:positive regulation of vasoconstriction; ISS:UniProtKB.
40Q9JHU4    4644   DYHC1_MOUSE Cytoplasmic dynein 1 heavy chain ...2090.093     43.1     26     41GO:0030286; C:dynein complex; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.::GO:0003777; F:microtubule motor activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0033962; P:cytoplasmic mRNA processing body assembly; IMP:BHF-UCL.::GO:0007018; P:microtubule-based movement; IEA:InterPro.::GO:0034063; P:stress granule assembly; IMP:BHF-UCL.::GO:0006810; P:transport; IEA:UniProtKB-KW.
41P38650    4644   DYHC1_RAT Cytoplasmic dynein 1 heavy chain 1 ...2090.11     42.7     26     41GO:0030286; C:dynein complex; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.::GO:0003777; F:microtubule motor activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:HGNC.
GO:0007018; P:microtubule-based movement; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
42Q14204    4646   DYHC1_HUMAN Cytoplasmic dynein 1 heavy chain ...2090.11     42.7     26     41GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005868; C:cytoplasmic dynein complex; NAS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042623; F:ATPase activity, coupled; NAS:UniProtKB.::GO:0003777; F:microtubule motor activity; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0033962; P:cytoplasmic mRNA processing body assembly; ISS:BHF-UCL.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0007018; P:microtubule-based movement; NAS:UniProtKB.::GO:0007052; P:mitotic spindle organization; NAS:UniProtKB.::GO:0034063; P:stress granule assembly; ISS:BHF-UCL.::GO:0006810; P:transport; IEA:UniProtKB-KW.
43Q8K988    777   LON_BUCAP Lon protease OS=Buchnera aphidicola...1330.12     42.4     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
44P49574    885   CLPC_ODOSI ATP-dependent Clp protease ATP-bin...1161.4     38.9     32     48GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0019538; P:protein metabolic process; IEA:InterPro.
45P0A9M0    784   LON_ECOLI Lon protease OS=Escherichia coli (s...1295.5     37     28     48GO:0005737; C:cytoplasm; IDA:EcoliWiki.::GO:0009295; C:nucleoid; IBA:RefGenome.
GO:0005524; F:ATP binding; IPI:EcoliWiki.::GO:0004176; F:ATP-dependent peptidase activity; IDA:EcoliWiki.::GO:0043565; F:sequence-specific DNA binding; IBA:RefGenome.::GO:0004252; F:serine-type endopeptidase activity; IMP:EcoliWiki.
GO:0006515; P:misfolded or incompletely synthesized protein catabolic process; IBA:RefGenome.::GO:0009408; P:response to heat; IEP:EcoliWiki.
46P0A9M1    784   LON_ECOL6 Lon protease OS=Escherichia coli O6...1295.5     37     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
47Q32JJ5    812   LON_SHIDS Lon protease OS=Shigella dysenteria...1295     37.4     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
48Q8G0I7    812   LON_BRUSU Lon protease OS=Brucella suis biova...1810.0007     49.7     29     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
49P0C113    812   LON_BRUAB Lon protease OS=Brucella abortus bi...1790.001     49.3     28     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
50Q2YPX3    812   LON_BRUA2 Lon protease OS=Brucella abortus (s...1790.001     49.3     28     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
51Q96JB1    4490   DYH8_HUMAN Dynein heavy chain 8, axonemal OS=...3700.001     49.3     23     38GO:0005858; C:axonemal dynein complex; NAS:UniProtKB.::GO:0035085; C:cilium axoneme; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.::GO:0003777; F:microtubule motor activity; NAS:UniProtKB.
GO:0001539; P:ciliary or flagellar motility; NAS:UniProtKB.::GO:0007018; P:microtubule-based movement; IEA:InterPro.
52P57549    777   LON_BUCAI Lon protease OS=(Acyrthosiphon pisu...1270.45     40.4     31     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
53Q19542    4171   DYHC2_CAEEL Cytoplasmic dynein 2 heavy chain ...3380.084     43.1     23     39GO:0060170; C:cilium membrane; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030286; C:dynein complex; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.::GO:0003777; F:microtubule motor activity; IEA:InterPro.
GO:0007635; P:chemosensory behavior; IMP:WormBase.::GO:0001539; P:ciliary or flagellar motility; IMP:WormBase.::GO:0042384; P:cilium assembly; IMP:WormBase.::GO:0007018; P:microtubule-based movement; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IGI:WormBase.::GO:0008104; P:protein localization; IMP:WormBase.
54A0JP86    1592   LAMC1_XENTR Laminin subunit gamma-1 OS=Xenopu...5250.001     48.9     22     40GO:0005604; C:basement membrane; IEA:UniProtKB-SubCell.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
55Q91XQ0    4731   DYH8_MOUSE Dynein heavy chain 8, axonemal OS=...3680.002     48.9     22     39GO:0035085; C:cilium axoneme; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0030286; C:dynein complex; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0009434; C:microtubule-based flagellum; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.::GO:0003777; F:microtubule motor activity; IEA:InterPro.
GO:0007018; P:microtubule-based movement; IEA:InterPro.
56P0C6U4    4441   R1A_CVHN2 Replicase polyprotein 1a OS=Human c...1460.33     41.2     26     49GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro.
GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro.
57Q8YHC6    812   LON_BRUME Lon protease OS=Brucella melitensis...1790.002     48.1     28     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
58P0CAW0    799   LON_CAUCR Lon protease OS=Caulobacter crescen...954.4     37.4     31     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
59B8GX12    799   LON_CAUCN Lon protease OS=Caulobacter crescen...954.4     37.4     31     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
60Q8VYJ7    964   CLPB4_ARATH Chaperone protein ClpB4, mitochon...1000.064     43.5     36     50GO:0009941; C:chloroplast envelope; IDA:TAIR.::GO:0009570; C:chloroplast stroma; IDA:TAIR.::GO:0005739; C:mitochondrion; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0016485; P:protein processing; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
61P46523    874   CLPA_BRANA ATP-dependent Clp protease ATP-bin...2290.004     47.4     26     46GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006289; P:nucleotide-excision repair; IEA:InterPro.::GO:0019538; P:protein metabolic process; IEA:InterPro.
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