Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
Home About FGC Use Cases Species List

UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR100W
Length:
347
Number of sequences:
5887
Description:
YLR100W ERG27 SGDID:S000004090, Chr XII from 341810-342853, Genome Release 64-1-1, Verified ORF, "3-keto sterol reductase, catalyzes the last of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; mutants are sterol auxotrophs"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q12452    347   ERG27_YEAST 3-keto-steroid reductase OS=Sacch...3470     711     100     100GO:0005789; C:endoplasmic reticulum membrane; IDA:SGD.::GO:0005811; C:lipid particle; IEA:UniProtKB-SubCell.::GO:0005741; C:mitochondrial outer membrane; IDA:SGD.
GO:0000253; F:3-keto sterol reductase activity; IMP:SGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006696; P:ergosterol biosynthetic process; IMP:SGD.
2Q6FIV3    348   ERG27_CANGA 3-keto-steroid reductase OS=NRRL ...3450     543     74     88
GO:0000253; F:3-keto sterol reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
3Q6CJC2    346   ERG27_KLULA 3-keto-steroid reductase OS=1267 ...3467e-177     501     69     82
GO:0000253; F:3-keto sterol reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
4Q74ZZ0    348   ERG27_ASHGO 3-keto-steroid reductase OS=Y-105...3333e-166     475     68     80
GO:0000253; F:3-keto sterol reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
5Q6BNP0    346   ERG27_DEBHA 3-keto-steroid reductase OS=0083 ...3464e-144     418     60     76
GO:0000253; F:3-keto sterol reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
6Q874K0    346   ERG27_CANAX 3-keto-steroid reductase OS=Candi...3434e-136     398     59     74
GO:0000253; F:3-keto sterol reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
7Q6CE88    343   ERG27_YARLI 3-keto-steroid reductase OS=lipol...3422e-80     255     43     59
GO:0000253; F:3-keto sterol reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
8O74732    338   ERG27_SCHPO 3-keto-steroid reductase OS=Schiz...3444e-58     197     32     55GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase.
GO:0000253; F:3-keto sterol reductase activity; ISS:PomBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006696; P:ergosterol biosynthetic process; ISS:PomBase.
9Q62904    334   DHB7_RAT 3-keto-steroid reductase OS=Rattus n...3234e-18     87     24     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0000253; F:3-keto sterol reductase activity; IEA:EC.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005148; F:prolactin receptor binding; IMP:RGD.
10O88736    334   DHB7_MOUSE 3-keto-steroid reductase OS=Mus mu...3237e-18     86.3     25     46GO:0005783; C:endoplasmic reticulum; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0000253; F:3-keto sterol reductase activity; IDA:MGI.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006695; P:cholesterol biosynthetic process; IDA:MGI.
11P56937    341   DHB7_HUMAN 3-keto-steroid reductase OS=Homo s...3520.000000000000001     80.1     23     44GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0000253; F:3-keto sterol reductase activity; IEA:EC.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; TAS:ProtInc.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome.
12Q4A054    234   Y0419_STAS1 Uncharacterized oxidoreductase SS...2360.000003     51.6     26     41
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
13P37959    280   YUSZ_BACSU Uncharacterized oxidoreductase yus...2500.0002     46.2     25     43
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
14Q566S6    309   DRS7B_DANRE Dehydrogenase/reductase SDR famil...2530.0005     45.1     21     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
15P39333    237   YJGI_ECOLI Uncharacterized oxidoreductase yjg...2300.003     42.4     22     37
GO:0035438; F:cyclic-di-GMP binding; IDA:EcoCyc.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0044010; P:single-species biofilm formation; IMP:EcoCyc.
16O74959    339   YJCD_SCHPO Uncharacterized oxidoreductase C73...2490.007     41.6     24     39
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
17Q8MI29    277   CBR1_MACFA Carbonyl reductase [NADPH] 1 OS=Ma...1840.012     40.4     27     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC.
GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0042373; P:vitamin K metabolic process; ISS:UniProtKB.
18Q5RCU5    277   CBR1_PONAB Carbonyl reductase [NADPH] 1 OS=Po...1800.013     40.4     27     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC.
GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0042373; P:vitamin K metabolic process; ISS:UniProtKB.
19P16152    277   CBR1_HUMAN Carbonyl reductase [NADPH] 1 OS=Ho...1800.018     40     27     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC.
GO:0017144; P:drug metabolic process; IDA:UniProtKB.::GO:0042373; P:vitamin K metabolic process; IDA:UniProtKB.
20P45200    252   Y1430_HAEIN Probable NADP-dependent dehydroge...2420.034     38.9     23     36
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
21O75828    277   CBR3_HUMAN Carbonyl reductase [NADPH] 3 OS=Ho...1010.05     38.5     30     46GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.
GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.::GO:0070402; F:NADPH binding; IDA:UniProtKB.
22P51976    406   DHI2_RABIT Corticosteroid 11-beta-dehydrogena...930.24     37     29     41GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
23P39577    252   DLTE_BACSU Uncharacterized oxidoreductase dlt...1840.39     35.8     23     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
24Q5RJY4    325   DRS7B_RAT Dehydrogenase/reductase SDR family ...2340.39     35.8     21     36GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
25P50233    400   DHI2_RAT Corticosteroid 11-beta-dehydrogenase...930.45     35.8     27     40GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD.
GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:RGD.::GO:0051287; F:NAD binding; IDA:RGD.::GO:0005496; F:steroid binding; IPI:RGD.
GO:0007565; P:female pregnancy; IEP:RGD.::GO:0008211; P:glucocorticoid metabolic process; IDA:RGD.::GO:0002017; P:regulation of blood volume by renal aldosterone; IMP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032094; P:response to food; IEP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IEP:RGD.]
26P0AFP4    269   YBBO_ECOLI Uncharacterized oxidoreductase ybb...950.46     35.8     28     44
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
27P0AFP5    269   YBBO_ECOL6 Uncharacterized oxidoreductase ybb...950.46     35.8     28     44
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
28Q28960    289   CBR1_PIG Carbonyl reductase [NADPH] 1 OS=Sus ...1030.5     35.4     29     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC.
GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0042373; P:vitamin K metabolic process; ISS:UniProtKB.
29Q4L8Y1    231   Y0585_STAHJ Uncharacterized oxidoreductase SH...970.59     35     28     48
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
30Q6P7J1    291   DHI1A_XENLA Hydroxysteroid 11-beta-dehydrogen...1120.85     35     26     43GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
31P80365    405   DHI2_HUMAN Corticosteroid 11-beta-dehydrogena...911.1     34.7     27     38GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0006704; P:glucocorticoid biosynthetic process; TAS:ProtInc.
records
Previous ‹‹ ›› Next Total records: 47 1 - 30
Elimate unknown annotation:
Filter for keyword on hit description:
Select upper E value:
Select lower bit score:
Select lower %idenity value:
Select lower %positive value:
Taxonomic division:
Lower limit on hit length:
Lower limit on alignment length::