rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
661 | P49139 | 366 | MAPK2_RABIT MAP kinase-activated protein kina... | 318 | 5e-26 | 115 | 28 | 46 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0070935; P:3'-UTR-mediated mRNA stabilization; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0006954; P:inflammatory response; ISS:UniProtKB.::GO:0044351; P:macropinocytosis; ISS:UniProtKB.::GO:0032675; P:regulation of interleukin-6 production; ISS:UniProtKB.::GO:0032680; P:regulation of tumor necrosis factor production; ISS:UniProtKB.::GO:0032496; P:response to lipopolysaccharide; ISS:UniProtKB.::GO:0002224; P:toll-like receptor signaling pathway; ISS:UniProtKB. | 662 | Q29502 | 524 | PAK2_RABIT Serine/threonine-protein kinase PA... | 230 | 5e-26 | 117 | 29 | 54 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0097194; P:execution phase of apoptosis; IMP:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB. | 663 | Q60592 | 1734 | MAST2_MOUSE Microtubule-associated serine/thr... | 308 | 5e-26 | 120 | 28 | 46 | GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0015630; C:microtubule cytoskeleton; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0008017; F:microtubule binding; IDA:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MGI. | | | | | | | | | | GO:0045075; P:regulation of interleukin-12 biosynthetic process; IDA:UniProtKB.::GO:0048515; P:spermatid differentiation; IDA:UniProtKB. | 664 | Q13177 | 524 | PAK2_HUMAN Serine/threonine-protein kinase PA... | 230 | 5e-26 | 117 | 29 | 54 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:BHF-UCL.::GO:0030296; F:protein tyrosine kinase activator activity; IDA:BHF-UCL. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:2001271; P:negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis; IDA:UniProtKB.::GO:0006469; P:negative regulation of protein kinase activity; TAS:ProtInc.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.::GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome. | 665 | Q8SWM6 | 488 | CDC5_ENCCU Probable cell cycle serine/threoni... | 237 | 5e-26 | 117 | 32 | 55 | GO:0005634; C:nucleus; IEA:UniProtKB-KW.::GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 666 | P11309 | 404 | PIM1_HUMAN Serine/threonine-protein kinase pi... | 196 | 5e-26 | 116 | 32 | 55 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0030145; F:manganese ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; IDA:UniProtKB.::GO:0007275; P:multicellular organismal development; TAS:ProtInc.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0031659; P:positive regulation of cyclin-dependent protein kinase activity involved in G1/S; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IMP:UniProtKB. | 667 | Q15349 | 733 | KS6A2_HUMAN Ribosomal protein S6 kinase alpha... | 300 | 6e-26 | 119 | 32 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 668 | Q6FN53 | 915 | STE20_CANGA Serine/threonine-protein kinase S... | 225 | 6e-26 | 119 | 31 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019236; P:response to pheromone; IEA:UniProtKB-KW. | 669 | Q03497 | 939 | STE20_YEAST Serine/threonine-protein kinase S... | 225 | 6e-26 | 119 | 29 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035174; F:histone serine kinase activity; IDA:SGD.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008349; F:MAP kinase kinase kinase kinase activity; IDA:SGD. | | | | | | | | | | GO:0000282; P:cellular bud site selection; IMP:SGD.::GO:0034605; P:cellular response to heat; IMP:SGD.::GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0010629; P:negative regulation of gene expression; IMP:SGD.::GO:0007232; P:osmosensory signaling pathway via Sho1 osmosensor; IMP:SGD.::GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; IMP:SGD.::GO:0043065; P:positive regulation of apoptotic process; IMP:SGD.::GO:0007124; P:pseudohyphal growth; IMP:SGD.::GO:0007096; P:regulation of exit from mitosis; IMP:SGD.::GO:0001402; P:signal transduction involved in filamentous growth; IMP:SGD.::GO:0035376; P:sterol import; IMP:SGD.::GO:0034063; P:stress granule assembly; IMP:SGD.::GO:0000011; P:vacuole inheritance; IMP:SGD. | 670 | A5A7I8 | 535 | CDPK5_SOLTU Calcium-dependent protein kinase ... | 188 | 7e-26 | 117 | 34 | 53 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 671 | Q9P1W9 | 311 | PIM2_HUMAN Serine/threonine-protein kinase pi... | 218 | 7e-26 | 114 | 31 | 52 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IDA:UniProtKB.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:UniProtKB.::GO:0007140; P:male meiosis; TAS:ProtInc.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0050821; P:protein stabilization; IMP:UniProtKB.::GO:0009615; P:response to virus; IEP:UniProtKB. | 672 | Q811L6 | 2618 | MAST4_MOUSE Microtubule-associated serine/thr... | 323 | 8e-26 | 119 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 673 | Q9UEE5 | 414 | ST17A_HUMAN Serine/threonine-protein kinase 1... | 218 | 8e-26 | 115 | 29 | 54 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:UniProtKB. | 674 | B4QK53 | 769 | PLK4_DROSI Serine/threonine-protein kinase PL... | 285 | 8e-26 | 118 | 26 | 46 | GO:0005814; C:centriole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 675 | P53681 | 602 | CRK_DAUCA CDPK-related protein kinase OS=Dauc... | 354 | 8e-26 | 117 | 27 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 676 | Q96GD4 | 344 | AURKB_HUMAN Aurora kinase B OS=Homo sapiens (... | 284 | 8e-26 | 114 | 26 | 49 | GO:0032133; C:chromosome passenger complex; IPI:UniProtKB.::GO:0000780; C:condensed nuclear chromosome, centromeric region; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030496; C:midbody; TAS:UniProtKB.::GO:0005819; C:spindle; TAS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; TAS:UniProtKB. | | | | | | | | | | GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0008608; P:attachment of spindle microtubules to kinetochore; TAS:UniProtKB.::GO:0034644; P:cellular response to UV; IDA:UniProtKB.::GO:0016570; P:histone modification; TAS:UniProtKB.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0002903; P:negative regulation of B cell apoptotic process; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0071777; P:positive regulation of cell cycle cytokinesis; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; IMP:UniProtKB.::GO:0051983; P:regulation of chromosome segregation; TAS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; IMP:UniProtKB. | 677 | Q8IYT8 | 1036 | ULK2_HUMAN Serine/threonine-protein kinase UL... | 261 | 9e-26 | 119 | 32 | 50 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0034045; C:pre-autophagosomal structure membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0007409; P:axonogenesis; IEA:InterPro.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0010506; P:regulation of autophagy; IDA:UniProtKB.::GO:0042594; P:response to starvation; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 678 | P0C605 | 671 | KGP1_MOUSE cGMP-dependent protein kinase 1 OS... | 320 | 9e-26 | 118 | 27 | 48 | GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IMP:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005246; F:calcium channel regulator activity; ISS:UniProtKB.::GO:0030553; F:cGMP binding; IDA:UniProtKB.::GO:0004692; F:cGMP-dependent protein kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0016358; P:dendrite development; IMP:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0090331; P:negative regulation of platelet aggregation; ISS:UniProtKB.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0043087; P:regulation of GTPase activity; ISS:UniProtKB.::GO:0007165; P:signal transduction; IDA:UniProtKB. | 679 | P31374 | 1356 | PSK1_YEAST Serine/threonine-protein kinase PS... | 388 | 9e-26 | 119 | 26 | 45 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IMP:SGD.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0045719; P:negative regulation of glycogen biosynthetic process; IMP:SGD.::GO:0060917; P:regulation of (1->6)-beta-D-glucan biosynthetic process; IGI:SGD.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. | 680 | Q9SZM3 | 484 | CDPKQ_ARATH Calcium-dependent protein kinase ... | 188 | 9e-26 | 116 | 34 | 54 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 681 | Q13976 | 671 | KGP1_HUMAN cGMP-dependent protein kinase 1 OS... | 320 | 9e-26 | 117 | 27 | 48 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005246; F:calcium channel regulator activity; IDA:UniProtKB.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0090331; P:negative regulation of platelet aggregation; IMP:UniProtKB.::GO:0043087; P:regulation of GTPase activity; IMP:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc. | 682 | P00516 | 671 | KGP1_BOVIN cGMP-dependent protein kinase 1 OS... | 320 | 9e-26 | 117 | 27 | 48 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005246; F:calcium channel regulator activity; ISS:UniProtKB.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0090331; P:negative regulation of platelet aggregation; ISS:UniProtKB.::GO:0043087; P:regulation of GTPase activity; ISS:UniProtKB. | 683 | Q9ZSA3 | 498 | CDPKM_ARATH Calcium-dependent protein kinase ... | 297 | 1e-25 | 116 | 30 | 46 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0009506; C:plasmodesma; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 684 | Q9FKW4 | 523 | CDPKS_ARATH Calcium-dependent protein kinase ... | 208 | 1e-25 | 116 | 30 | 50 | GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 685 | O77676 | 671 | KGP1_RABIT cGMP-dependent protein kinase 1 OS... | 320 | 1e-25 | 117 | 27 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005246; F:calcium channel regulator activity; ISS:UniProtKB.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0090331; P:negative regulation of platelet aggregation; ISS:UniProtKB.::GO:0043087; P:regulation of GTPase activity; ISS:UniProtKB. | 686 | Q7ZVS3 | 940 | PLK4_DANRE Serine/threonine-protein kinase PL... | 284 | 1e-25 | 118 | 28 | 47 | GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB. | 687 | O97143 | 769 | PLK4_DROME Serine/threonine-protein kinase PL... | 285 | 1e-25 | 118 | 26 | 46 | GO:0005814; C:centriole; IDA:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007099; P:centriole replication; IMP:FlyBase.::GO:0007052; P:mitotic spindle organization; IMP:FlyBase.::GO:0046599; P:regulation of centriole replication; IDA:FlyBase.::GO:0007288; P:sperm axoneme assembly; IMP:FlyBase. | 688 | Q62829 | 544 | PAK3_RAT Serine/threonine-protein kinase PAK ... | 200 | 1e-25 | 116 | 31 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051020; F:GTPase binding; IDA:RGD.::GO:0004708; F:MAP kinase kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007409; P:axonogenesis; ISS:UniProtKB.::GO:0016358; P:dendrite development; ISS:UniProtKB.::GO:0030833; P:regulation of actin filament polymerization; ISS:UniProtKB. | 689 | Q62070 | 370 | PIM2_MOUSE Serine/threonine-protein kinase pi... | 198 | 1e-25 | 114 | 32 | 54 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IDA:MGI.::GO:0008637; P:apoptotic mitochondrial changes; IDA:MGI.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0010508; P:positive regulation of autophagy; IMP:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0050821; P:protein stabilization; IDA:UniProtKB. | 690 | A1Z7T0 | 1190 | PKN_DROME Serine/threonine-protein kinase N O... | 272 | 1e-25 | 118 | 30 | 49 | GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007391; P:dorsal closure; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007472; P:wing disc morphogenesis; IMP:UniProtKB. | 691 | Q8BTW9 | 593 | PAK4_MOUSE Serine/threonine-protein kinase PA... | 284 | 1e-25 | 117 | 27 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW. |