UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YLR086W

Length:

1418

Number of sequences:

5887

Description:

YLR086W SMC4 SGDID:S000004076, Chr XII from 302243-306499, Genome Release 64-1-1, Verified ORF, "Subunit of the condensin complex; reorganizes chromosomes during cell division; forms a complex with Smc2p that has ATP-hydrolyzing and DNA-binding activity; required for tRNA gene clustering at the nucleolus; potential Cdc28p substrate"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
61	A9BZW2	1175	SMC_DELAS Chromosome partition protein Smc OS...	259	0.0000000005	68.2	27	45	GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
									GO:0030261; P:chromosome condensation; IEA:InterPro.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
62	Q81ZL2	1169	SMC_COXBU Chromosome partition protein Smc OS...	674	2e-16	89	23	43	GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
									GO:0030261; P:chromosome condensation; IEA:InterPro.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
63	Q3JR19	1170	SMC_BURP1 Chromosome partition protein Smc OS...	255	0.0000000006	67.8	27	45	GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
									GO:0030261; P:chromosome condensation; IEA:InterPro.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
64	Q7UQV4	1192	SMC_RHOBA Chromosome partition protein Smc OS...	160	0.62	38.5	23	46	GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IEA:InterPro.
									GO:0030261; P:chromosome condensation; IEA:InterPro.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
65	Q09591	1244	MIX1_CAEEL Mitotic chromosome and X-chromosom...	187	0.0000000000006	77.8	28	49	GO:0000775; C:chromosome, centromeric region; IDA:WormBase.::GO:0000793; C:condensed chromosome; IDA:WormBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0042464; P:dosage compensation by hypoactivation of X chromosome; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040039; P:inductive cell migration; IMP:WormBase.::GO:0007076; P:mitotic chromosome condensation; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.
66	Q9CBT5	1203	SMC_MYCLE Chromosome partition protein Smc OS...	131	0.0000000000002	79	31	53	GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
									GO:0030261; P:chromosome condensation; IEA:InterPro.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
67	Q10970	1205	SMC_MYCTU Chromosome partition protein Smc OS...	131	0.00000000000004	81.6	30	55	GO:0005618; C:cell wall; IDA:MTBBASE.::GO:0005694; C:chromosome; IEA:InterPro.::GO:0005829; C:cytosol; IDA:MTBBASE.::GO:0005886; C:plasma membrane; IDA:MTBBASE.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
									GO:0030261; P:chromosome condensation; IEA:InterPro.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
68	P47540	982	SMC_MYCGE Chromosome partition protein Smc OS...	416	0.002	47	22	44	GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
									GO:0030261; P:chromosome condensation; IEA:InterPro.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
69	Q73VM3	1196	SMC_MYCPA Chromosome partition protein Smc OS...	131	0.00000000000004	81.6	29	54	GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
									GO:0030261; P:chromosome condensation; IEA:InterPro.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
70	P50533	1203	SMC2_XENLA Structural maintenance of chromoso...	86	0.00000000000003	82	38	70	GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
71	P75361	982	SMC_MYCPN Chromosome partition protein Smc OS...	406	0.0000000006	67.8	25	46	GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
									GO:0030261; P:chromosome condensation; IEA:InterPro.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
72	Q8CG48	1191	SMC2_MOUSE Structural maintenance of chromoso...	366	0.000002	56.6	27	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
73	P15016	173	YAT3_RHORU Uncharacterized protein in ATPase ...	141	0.000000000002	72	29	50
74	Q8KBS6	1183	SMC_CHLTE Chromosome partition protein Smc OS...	98	0.000000000004	75.1	37	53	GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
									GO:0030261; P:chromosome condensation; IEA:InterPro.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
75	Q8REH4	1183	SMC_FUSNN Chromosome partition protein Smc OS...	206	0.000000001	67	24	49	GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
									GO:0030261; P:chromosome condensation; IEA:InterPro.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
76	Q8I1U7	1193	SMC3_PLAF7 Structural maintenance of chromoso...	98	0.001	47.4	29	50	GO:0000785; C:chromatin; ISS:UniProtKB.::GO:0034990; C:nuclear mitotic cohesin complex; ISS:UniProtKB.
									GO:0003680; F:AT DNA binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000070; P:mitotic sister chromatid segregation; ISS:UniProtKB.::GO:0006275; P:regulation of DNA replication; ISS:UniProtKB.
77	Q9C5Y4	1175	SMC21_ARATH Structural maintenance of chromos...	93	0.000000003	65.5	39	63	GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
78	Q96SB8	1091	SMC6_HUMAN Structural maintenance of chromoso...	54	0.46	38.9	37	61	GO:0000781; C:chromosome, telomeric region; IDA:UniProtKB.::GO:0016605; C:PML body; IDA:UniProtKB.::GO:0030915; C:Smc5-Smc6 complex; IDA:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0090398; P:cellular senescence; IMP:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0000722; P:telomere maintenance via recombination; IMP:UniProtKB.
79	P62134	993	RAD50_METMP DNA double-strand break repair Ra...	179	0.0000004	58.5	28	50
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
80	Q924W5	1097	SMC6_MOUSE Structural maintenance of chromoso...	311	0.22	39.7	23	44	GO:0000781; C:chromosome, telomeric region; ISS:UniProtKB.::GO:0016605; C:PML body; ISS:UniProtKB.::GO:0030915; C:Smc5-Smc6 complex; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0090398; P:cellular senescence; ISS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0000722; P:telomere maintenance via recombination; ISS:UniProtKB.
81	Q58718	1005	RAD50_METJA DNA double-strand break repair Ra...	557	0.00003	52.4	24	47
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
82	O33600	886	RAD50_SULAC DNA double-strand break repair Ra...	114	0.0001	50.8	35	54
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
83	P58302	895	RAD50_THEVO DNA double-strand break repair Ra...	97	1.5	37	32	49
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
84	Q8CG46	1101	SMC5_MOUSE Structural maintenance of chromoso...	416	0.21	40	22	43	GO:0000781; C:chromosome, telomeric region; ISS:UniProtKB.::GO:0016605; C:PML body; ISS:UniProtKB.::GO:0030915; C:Smc5-Smc6 complex; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0090398; P:cellular senescence; ISS:UniProtKB.::GO:0000724; P:double-strand break repair via homologous recombination; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0034184; P:positive regulation of maintenance of mitotic sister chromatid cohesion; ISS:UniProtKB.::GO:0045842; P:positive regulation of mitotic metaphase/anaphase transition; ISS:UniProtKB.::GO:0000722; P:telomere maintenance via recombination; ISS:UniProtKB.
85	O13710	1076	SMC5_SCHPO Structural maintenance of chromoso...	170	0.63	38.1	23	45	GO:0000935; C:barrier septum; IEA:UniProtKB-SubCell.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0030915; C:Smc5-Smc6 complex; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:PomBase.
									GO:0000724; P:double-strand break repair via homologous recombination; TAS:PomBase.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0048478; P:replication fork protection; IC:PomBase.
86	O29230	886	RAD50_ARCFU DNA double-strand break repair Ra...	360	0.003	45.8	25	45
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
87	A8AU71	361	RECF_STRGC DNA replication and repair protein...	69	0.005	44.7	29	61	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
88	Q802R8	1090	SMC6_TAKRU Structural maintenance of chromoso...	143	0.009	44.3	26	42	GO:0000781; C:chromosome, telomeric region; ISS:UniProtKB.::GO:0016605; C:PML body; ISS:UniProtKB.::GO:0030915; C:Smc5-Smc6 complex; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0090398; P:cellular senescence; ISS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0000722; P:telomere maintenance via recombination; ISS:UniProtKB.
89	Q8IY18	1101	SMC5_HUMAN Structural maintenance of chromoso...	205	0.077	41.2	22	41	GO:0000781; C:chromosome, telomeric region; IDA:UniProtKB.::GO:0016605; C:PML body; IDA:UniProtKB.::GO:0030915; C:Smc5-Smc6 complex; IDA:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0090398; P:cellular senescence; IMP:UniProtKB.::GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0034184; P:positive regulation of maintenance of mitotic sister chromatid cohesion; IMP:UniProtKB.::GO:0045842; P:positive regulation of mitotic metaphase/anaphase transition; IMP:UniProtKB.::GO:0000722; P:telomere maintenance via recombination; IMP:UniProtKB.
90	Q9YFZ1	919	RAD50_AERPE DNA double-strand break repair Ra...	475	0.012	43.9	24	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
91	Q9RKQ4	280	HMUV_STRCO Hemin import ATP-binding protein H...	66	0.02	42.4	36	55	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.::GO:0005215; F:transporter activity; IEA:InterPro.

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