rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q9P258 | 522 | RCC2_HUMAN Protein RCC2 OS=Homo sapiens (Huma... | 85 | 4.6 | 33.9 | 26 | 46 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000236; P:mitotic prometaphase; TAS:Reactome. | 32 | P25183 | 424 | RCC1_XENLA Regulator of chromosome condensati... | 179 | 1.3 | 35.4 | 23 | 36 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 33 | Q91ZR4 | 698 | NEK8_MOUSE Serine/threonine-protein kinase Ne... | 173 | 0.11 | 39.3 | 25 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0072372; C:primary cilium; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 34 | Q8BK67 | 520 | RCC2_MOUSE Protein RCC2 OS=Mus musculus (Mous... | 334 | 0.0003 | 47.4 | 23 | 40 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 35 | Q52KW8 | 513 | RCC2_XENLA Protein RCC2 homolog OS=Xenopus la... | 164 | 0.47 | 37 | 24 | 41 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 36 | Q6NYE2 | 495 | RCC2_DANRE Protein RCC2 homolog OS=Danio reri... | 199 | 0.076 | 39.7 | 23 | 41 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 37 | Q86SG6 | 692 | NEK8_HUMAN Serine/threonine-protein kinase Ne... | 212 | 0.17 | 38.5 | 22 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0072372; C:primary cilium; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 38 | Q18211 | 569 | RCC1_CAEEL Regulator of chromosome condensati... | 238 | 0.91 | 36.2 | 25 | 41 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000910; P:cytokinesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0016246; P:RNA interference; IMP:WormBase. | 39 | Q54Q89 | 487 | RCCDC_DICDI RCC1 repeat-containing protein DD... | 204 | 0.001 | 45.1 | 25 | 40 | | | | | | | | | | | | | | | | | | | | | | 40 | Q9NB71 | 5233 | HIW_DROME E3 ubiquitin-protein ligase highwir... | 118 | 0.74 | 36.6 | 28 | 42 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IDA:FlyBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:FlyBase. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007628; P:adult walking behavior; NAS:FlyBase.::GO:0006914; P:autophagy; IDA:FlyBase.::GO:0030509; P:BMP signaling pathway; IPI:UniProtKB.::GO:0040011; P:locomotion; NAS:FlyBase.::GO:0030514; P:negative regulation of BMP signaling pathway; IGI:UniProtKB.::GO:0045886; P:negative regulation of synaptic growth at neuromuscular junction; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050808; P:synapse organization; IDA:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 41 | Q9CYF5 | 461 | WBS16_MOUSE Williams-Beuren syndrome chromoso... | 178 | 0.006 | 43.1 | 25 | 39 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; NAS:UniProtKB. | | | | | | | | | | | 42 | Q90XC2 | 697 | NEK8_DANRE Serine/threonine-protein kinase Ne... | 435 | 0.008 | 42.7 | 20 | 37 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 43 | Q9UGK8 | 458 | SRGEF_HUMAN Secretion-regulating guanine nucl... | 132 | 7.5 | 33.1 | 26 | 39 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; TAS:UniProtKB. | | | | | | | | | | GO:0050709; P:negative regulation of protein secretion; IDA:HGNC.::GO:0007165; P:signal transduction; TAS:UniProtKB. | 44 | Q54X24 | 512 | RCCDA_DICDI RCC1 domain-containing protein DD... | 57 | 1.1 | 35.8 | 35 | 53 | | | | | | | | | | | | | | | | | | | | | | 45 | Q8SSY6 | 1887 | SPKUL_DICDI Bifunctional serine/threonine-pro... | 112 | 0.76 | 36.6 | 26 | 43 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 46 | O42645 | 351 | YF94_SCHPO RCC1 repeat-containing protein C10... | 169 | 0.012 | 42 | 28 | 37 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0007017; P:microtubule-based process; ISS:PomBase.::GO:0006400; P:tRNA modification; ISS:PomBase. | 47 | P52499 | 464 | RCC1_CANAX Protein RCC1 OS=Candida albicans (... | 108 | 3.2 | 34.3 | 25 | 41 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 48 | Q96I51 | 464 | WBS16_HUMAN Williams-Beuren syndrome chromoso... | 256 | 0.096 | 39.3 | 23 | 39 | | | | | | | | | | | | | | | | | | | | | | 49 | P28745 | 539 | RCC1_SCHPO Protein pim1 OS=Schizosaccharomyce... | 112 | 0.16 | 38.5 | 22 | 38 | GO:0000790; C:nuclear chromatin; NAS:PomBase. | | | | | | | | | | GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; IGI:PomBase. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; IMP:PomBase.::GO:0006406; P:mRNA export from nucleus; IMP:PomBase.::GO:0031291; P:Ran protein signal transduction; IGI:PomBase.::GO:0060623; P:regulation of chromosome condensation; IGI:PomBase.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IMP:PomBase.::GO:0006407; P:rRNA export from nucleus; ISS:PomBase.::GO:0090307; P:spindle assembly involved in mitosis; TAS:PomBase. | 50 | O75592 | 4640 | MYCB2_HUMAN Probable E3 ubiquitin-protein lig... | 73 | 0.19 | 38.5 | 26 | 51 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 51 | Q3MHW0 | 464 | SRGEF_BOVIN Secretion-regulating guanine nucl... | 238 | 0.28 | 37.7 | 19 | 34 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 52 | P25171 | 547 | RCC1_DROME Regulator of chromosome condensati... | 56 | 1.6 | 35.4 | 30 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007417; P:central nervous system development; IDA:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007346; P:regulation of mitotic cell cycle; IDA:UniProtKB.::GO:0050767; P:regulation of neurogenesis; IMP:FlyBase.::GO:0046822; P:regulation of nucleocytoplasmic transport; IMP:FlyBase. | 53 | Q54VW7 | 1203 | GACGG_DICDI Rho GTPase-activating protein gac... | 156 | 0.29 | 37.7 | 28 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 54 | Q7TPH6 | 4711 | MYCB2_MOUSE Probable E3 ubiquitin-protein lig... | 73 | 0.38 | 37.7 | 26 | 49 | GO:0030424; C:axon; IDA:MGI.::GO:0015630; C:microtubule cytoskeleton; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0021785; P:branchiomotor neuron axon guidance; IMP:MGI.::GO:0021952; P:central nervous system projection neuron axonogenesis; IMP:MGI.::GO:0051493; P:regulation of cytoskeleton organization; IMP:MGI.::GO:0032880; P:regulation of protein localization; IMP:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 55 | P31386 | 333 | ATS1_YEAST Protein ATS1 OS=Saccharomyces cere... | 157 | 0.88 | 35.8 | 23 | 39 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | | | | | | | | | | | GO:0007117; P:budding cell bud growth; IGI:SGD.::GO:0000226; P:microtubule cytoskeleton organization; IMP:SGD.::GO:0002098; P:tRNA wobble uridine modification; IMP:SGD. | 56 | Q17551 | 3766 | RPM1_CAEEL E3 ubiquitin-protein ligase rpm-1 ... | 76 | 0.92 | 36.6 | 30 | 45 | GO:0030424; C:axon; IDA:WormBase.::GO:0031594; C:neuromuscular junction; IDA:WormBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:WormBase.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0040011; P:locomotion; IGI:WormBase.::GO:0043409; P:negative regulation of MAPK cascade; IGI:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0031647; P:regulation of protein stability; IMP:WormBase.::GO:0050807; P:regulation of synapse organization; IMP:WormBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 57 | Q5BIW4 | 1657 | ALS2_PANTR Alsin OS=Pan troglodytes (Chimpanz... | 34 | 1.3 | 35.8 | 38 | 65 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0043234; C:protein complex; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB.::GO:0042598; C:vesicular fraction; ISS:UniProtKB. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043539; F:protein serine/threonine kinase activator activity; ISS:UniProtKB.::GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; ISS:UniProtKB.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0001662; P:behavioral fear response; ISS:UniProtKB.::GO:0016197; P:endosome transport; ISS:UniProtKB.::GO:0007626; P:locomotory behavior; ISS:UniProtKB.::GO:0007528; P:neuromuscular junction development; ISS:UniProtKB.::GO:0048812; P:neuron projection morphogenesis; ISS:UniProtKB.::GO:0032855; P:positive regulation of Rac GTPase activity; ISS:UniProtKB.::GO:0008104; P:protein localization; ISS:UniProtKB.::GO:0001881; P:receptor recycling; ISS:UniProtKB.::GO:0051036; P:regulation of endosome size; ISS:UniProtKB.::GO:0032313; P:regulation of Rab GTPase activity; ISS:UniProtKB.::GO:0006979; P:response to oxidative stress; ISS:UniProtKB.::GO:0035249; P:synaptic transmission, glutamatergic; ISS:UniProtKB.::GO:0016050; P:vesicle organization; ISS:UniProtKB. | 58 | Q96Q42 | 1657 | ALS2_HUMAN Alsin OS=Homo sapiens (Human). GN=... | 34 | 1.3 | 35.8 | 38 | 65 | GO:0005813; C:centrosome; IDA:MGI.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0030426; C:growth cone; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0043234; C:protein complex; IDA:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0043539; F:protein serine/threonine kinase activator activity; IDA:UniProtKB.::GO:0017137; F:Rab GTPase binding; IDA:UniProtKB.::GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IDA:UniProtKB.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IDA:UniProtKB.::GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; NAS:UniProtKB. | | | | | | | | | | GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0007032; P:endosome organization; NAS:UniProtKB.::GO:0032855; P:positive regulation of Rac GTPase activity; IDA:UniProtKB.::GO:0035022; P:positive regulation of Rac protein signal transduction; IC:UniProtKB.::GO:0051036; P:regulation of endosome size; IEP:UniProtKB. | 59 | Q80YD6 | 464 | SRGEF_MOUSE Secretion-regulating guanine nucl... | 111 | 5.6 | 33.5 | 28 | 41 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 60 | Q46XB7 | 294 | AROE_CUPPJ Shikimate dehydrogenase OS=eutroph... | 44 | 8.6 | 32.7 | 34 | 61 | | | | | | | | | | | GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004764; F:shikimate 3-dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW. | 61 | Q54HT1 | 1336 | TIRA_DICDI Protein tirA OS=Dictyostelium disc... | 42 | 8.6 | 33.1 | 43 | 52 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | | | | | | | | | | | GO:0008283; P:cell proliferation; IMP:dictyBase.::GO:0006952; P:defense response; IMP:dictyBase.::GO:0007165; P:signal transduction; IEA:InterPro. |