Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR058C
Length:
469
Number of sequences:
5887
Description:
YLR058C SHM2 SGDID:S000004048, Chr XII from 259401-257992, Genome Release 64-1-1, reverse complement, Verified ORF, "Cytosolic serine hydroxymethyltransferase, converts serine to glycine plus 5,10 methylenetetrahydrofolate; major isoform involved in generating precursors for purine, pyrimidine, amino acid, and lipid biosynthesis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
781O83349    574   GLYA_TREPA Serine hydroxymethyltransferase OS...4621e-72     246     35     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
782A8M1D3    478   GLYA_SALAI Serine hydroxymethyltransferase OS...4377e-72     241     35     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
783A0R2V7    490   GLYA_MYCS2 Serine hydroxymethyltransferase OS...4312e-71     240     37     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
784A4X6P4    478   GLYA_SALTO Serine hydroxymethyltransferase OS...4359e-68     230     34     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
785O29406    438   GLYA_ARCFU Serine hydroxymethyltransferase OS...4454e-58     203     34     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
786P50434    260   GLYA_CORS1 Serine hydroxymethyltransferase OS...2642e-56     194     41     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
787A0RYP2    441   GLYA_CENSY Serine hydroxymethyltransferase OS...4312e-52     189     32     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
788O27433    423   GLYA_METTH Serine hydroxymethyltransferase OS...4256e-51     184     32     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
789Q58992    429   GLYA_METJA Serine hydroxymethyltransferase OS...4292e-50     182     33     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:InterPro.::GO:0016829; F:lyase activity; IEA:UniProtKB-KW.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
790A5UMW4    422   GLYA_METS3 Serine hydroxymethyltransferase OS...4046e-50     181     32     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
791Q0W3U6    423   GLYA_UNCMA Serine hydroxymethyltransferase OS...4291e-49     180     32     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
792Q2NEA8    422   GLYA_METST Serine hydroxymethyltransferase OS...4213e-49     179     32     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
793P50436    423   GLYA_METTM Serine hydroxymethyltransferase OS...4226e-49     178     32     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
794A9A3Y9    440   GLYA_NITMS Serine hydroxymethyltransferase OS...4231e-47     175     32     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
795Q5JF06    431   GLYA_PYRKO Serine hydroxymethyltransferase OS...4071e-45     169     32     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
796A6UVV2    429   GLYA_META3 Serine hydroxymethyltransferase OS...4114e-45     168     32     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
797C5A6G2    427   GLYA_THEGJ Serine hydroxymethyltransferase OS...4064e-45     168     32     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
798Q8U039    427   GLYA_PYRFU Serine hydroxymethyltransferase OS...4108e-45     167     31     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
799O59347    427   GLYA_PYRHO Serine hydroxymethyltransferase OS...4102e-44     166     31     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
800Q9V1B2    427   GLYA_PYRAB Serine hydroxymethyltransferase OS...4076e-44     164     31     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:InterPro.::GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
801B1YA29    430   GLYA_THENV Serine hydroxymethyltransferase OS...4022e-43     163     31     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
802A3DNJ6    439   GLYA_STAMF Serine hydroxymethyltransferase OS...4103e-43     163     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
803A4WGZ8    429   GLYA_PYRAR Serine hydroxymethyltransferase OS...4025e-43     162     31     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
804A1RTI0    430   GLYA_PYRIL Serine hydroxymethyltransferase OS...4021e-42     161     32     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
805Q9YAH7    439   GLYA_AERPE Serine hydroxymethyltransferase OS...4412e-42     160     29     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
806Q8TZ19    428   GLYA_METKA Serine hydroxymethyltransferase OS...4454e-42     160     31     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
807Q8ZYF9    430   GLYA_PYRAE Serine hydroxymethyltransferase OS...4075e-42     159     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
808A3MS37    430   GLYA_PYRCJ Serine hydroxymethyltransferase OS...4012e-41     158     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
809B1L5K9    434   GLYA_KORCO Serine hydroxymethyltransferase OS...4272e-41     157     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
810A8MBA2    431   GLYA_CALMQ Serine hydroxymethyltransferase OS...4181e-40     155     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
811Q6L1F6    433   GLYA_PICTO Serine hydroxymethyltransferase OS...3942e-40     155     32     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
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