Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR058C
Length:
469
Number of sequences:
5887
Description:
YLR058C SHM2 SGDID:S000004048, Chr XII from 259401-257992, Genome Release 64-1-1, reverse complement, Verified ORF, "Cytosolic serine hydroxymethyltransferase, converts serine to glycine plus 5,10 methylenetetrahydrofolate; major isoform involved in generating precursors for purine, pyrimidine, amino acid, and lipid biosynthesis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
721B7GTL3    435   GLYA_BIFLS Serine hydroxymethyltransferase OS...4106e-97     305     40     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
722B3QUG2    440   GLYA_CHLT3 Serine hydroxymethyltransferase OS...4141e-96     304     43     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
723B2US14    416   GLYA_HELPS Serine hydroxymethyltransferase OS...3972e-96     303     42     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
724Q30P60    420   GLYA2_SULDN Serine hydroxymethyltransferase 2...4042e-96     303     45     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
725Q5YQ76    431   GLYA_NOCFA Serine hydroxymethyltransferase OS...4132e-96     304     40     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
726Q3IRX5    424   GLYA_NATPD Serine hydroxymethyltransferase OS...4222e-96     303     40     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
727P56089    416   GLYA_HELPY Serine hydroxymethyltransferase OS...3974e-96     303     42     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
728Q5V3D7    415   GLYA_HALMA Serine hydroxymethyltransferase OS...4434e-96     302     39     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
729Q4A6A3    421   GLYA_MYCS5 Serine hydroxymethyltransferase OS...4235e-96     302     41     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
730B6YS43    426   GLYA_AZOPC Serine hydroxymethyltransferase OS...4065e-96     303     43     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
731B6JPT2    416   GLYA_HELP2 Serine hydroxymethyltransferase OS...3975e-96     302     42     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
732Q30YL7    412   GLYA_DESDG Serine hydroxymethyltransferase OS...4075e-96     302     44     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
733A1AWS2    417   GLYA_RUTMC Serine hydroxymethyltransferase OS...4017e-96     302     42     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
734Q9KMP4    435   GLYA2_VIBCH Serine hydroxymethyltransferase 2...4117e-96     302     43     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
735Q7UQN2    420   GLYA_RHOBA Serine hydroxymethyltransferase OS...4079e-96     301     42     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
736Q2FLH5    414   GLYA_METHJ Serine hydroxymethyltransferase OS...4549e-96     301     39     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
737A9AYB7    419   GLYA_HERA2 Serine hydroxymethyltransferase OS...4051e-95     301     42     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
738Q7U2X3    425   GLYA2_MYCBO Serine hydroxymethyltransferase 2...4142e-95     301     40     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
739O53615    425   GLYA2_MYCTU Serine hydroxymethyltransferase 2...4142e-95     301     40     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:MTBBASE.
GO:0004372; F:glycine hydroxymethyltransferase activity; IDA:MTBBASE.::GO:0042803; F:protein homodimerization activity; IPI:MTBBASE.::GO:0030170; F:pyridoxal phosphate binding; IDA:MTBBASE.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IDA:MTBBASE.::GO:0006563; P:L-serine metabolic process; IDA:MTBBASE.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
740Q057P9    417   GLYA_BUCCC Serine hydroxymethyltransferase OS...4063e-95     300     40     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
741B0UML5    433   GLYA_METS4 Serine hydroxymethyltransferase OS...4084e-95     300     43     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
742Q93PM7    434   GLYA_CORGL Serine hydroxymethyltransferase OS...4244e-95     300     39     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
743A4QCW6    434   GLYA_CORGB Serine hydroxymethyltransferase OS...4244e-95     300     39     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
744Q9K6G4    413   GLYA_BACHD Serine hydroxymethyltransferase OS...3995e-95     300     44     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
745A7ZFA4    414   GLYA_CAMC1 Serine hydroxymethyltransferase OS...3977e-95     299     41     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
746Q1CUX5    416   GLYA_HELPH Serine hydroxymethyltransferase OS...3977e-95     299     41     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
747B5Z9V7    416   GLYA_HELPG Serine hydroxymethyltransferase OS...3979e-95     299     41     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
748A5V5D1    438   GLYA_SPHWW Serine hydroxymethyltransferase OS...4152e-94     299     44     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
749A5CU18    425   GLYA_CLAM3 Serine hydroxymethyltransferase OS...4112e-94     298     41     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
750A7GX48    414   GLYA_CAMC5 Serine hydroxymethyltransferase OS...3973e-94     298     42     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
751B1VZY7    419   GLYA_STRGG Serine hydroxymethyltransferase OS...4163e-94     298     42     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
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