FGC: Single Locus Summary

UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YLR058C

Length:

469

Number of sequences:

5887

Description:

YLR058C SHM2 SGDID:S000004048, Chr XII from 259401-257992, Genome Release 64-1-1, reverse complement, Verified ORF, "Cytosolic serine hydroxymethyltransferase, converts serine to glycine plus 5,10 methylenetetrahydrofolate; major isoform involved in generating precursors for purine, pyrimidine, amino acid, and lipid biosynthesis"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
61	A3DEB1	412	GLYA_CLOTH Serine hydroxymethyltransferase OS...	401	3e-117	357	48	64	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
62	B8I2N8	412	GLYA_CLOCE Serine hydroxymethyltransferase OS...	408	3e-117	357	46	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
63	B1KXQ5	413	GLYA_CLOBM Serine hydroxymethyltransferase OS...	427	3e-117	357	44	64	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
64	C3L181	413	GLYA_CLOB6 Serine hydroxymethyltransferase OS...	427	3e-117	357	44	64	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
65	O66776	428	GLYA_AQUAE Serine hydroxymethyltransferase OS...	444	4e-117	357	45	61	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
66	A5I526	413	GLYA_CLOBH Serine hydroxymethyltransferase OS...	427	8e-117	356	44	64	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
67	A7FWM6	413	GLYA_CLOB1 Serine hydroxymethyltransferase OS...	427	8e-117	356	44	64	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
68	A6TQQ1	410	GLYA_ALKMQ Serine hydroxymethyltransferase OS...	410	1e-116	355	46	64	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
69	B3PBD6	421	GLYA_CELJU Serine hydroxymethyltransferase OS...	404	1e-116	355	46	66	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
70	C4ZH69	413	GLYA_EUBR3 Serine hydroxymethyltransferase OS...	420	1e-116	355	47	64	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
71	B2A3H6	412	GLYA_NATTJ Serine hydroxymethyltransferase OS...	422	3e-116	354	43	64	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
72	A0PZX4	411	GLYA_CLONN Serine hydroxymethyltransferase OS...	407	3e-116	354	46	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
73	B1V975	413	GLYA_PHYAS Serine hydroxymethyltransferase OS...	457	3e-116	354	42	61	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
74	D3DKC4	427	GLYA_HYDTT Serine hydroxymethyltransferase OS...	407	1e-115	353	47	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:HAMAP.::GO:0016829; F:lyase activity; IEA:UniProtKB-KW.::GO:0030170; F:pyridoxal phosphate binding; IEA:HAMAP.
									GO:0019264; P:glycine biosynthetic process from serine; IEA:HAMAP.::GO:0006730; P:one-carbon metabolic process; IEA:HAMAP.
75	Q74LC1	411	GLYA_LACJO Serine hydroxymethyltransferase OS...	427	1e-115	352	45	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
76	Q8XJ32	410	GLYA_CLOPE Serine hydroxymethyltransferase OS...	402	2e-115	352	45	64	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
77	Q0TP32	410	GLYA_CLOP1 Serine hydroxymethyltransferase OS...	402	2e-115	352	45	64	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
78	Q3APN5	438	GLYA_CHLCH Serine hydroxymethyltransferase OS...	429	4e-115	352	45	61	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
79	A0B8J6	414	GLYA_METTP Serine hydroxymethyltransferase OS...	407	6e-115	351	46	62	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
80	Q5FNK4	434	GLYA_GLUOX Serine hydroxymethyltransferase OS...	415	6e-115	352	46	62	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
81	Q74CR5	415	GLYA_GEOSL Serine hydroxymethyltransferase OS...	426	1e-114	350	44	62	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
82	Q6AM21	425	GLYA_DESPS Serine hydroxymethyltransferase OS...	422	1e-114	350	45	62	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
83	B2KER5	415	GLYA_ELUMP Serine hydroxymethyltransferase OS...	410	1e-114	350	46	62	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
84	Q0SRQ2	410	GLYA_CLOPS Serine hydroxymethyltransferase OS...	402	2e-114	349	45	64	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
85	B5E8U0	415	GLYA_GEOBB Serine hydroxymethyltransferase OS...	397	2e-114	349	46	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
86	B3R0G5	419	GLYA_PHYMT Serine hydroxymethyltransferase OS...	404	4e-114	349	46	64	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
87	Q5SI56	407	GLYA_THET8 Serine hydroxymethyltransferase OS...	401	9e-114	348	47	64	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
88	B8E008	414	GLYA_DICTD Serine hydroxymethyltransferase OS...	406	1e-113	347	45	65	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
89	Q24MM6	417	GLYA_DESHY Serine hydroxymethyltransferase OS...	409	2e-113	347	45	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
90	Q046F8	411	GLYA_LACGA Serine hydroxymethyltransferase OS...	402	2e-113	347	46	65	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
91	A6Q478	415	GLYA_NITSB Serine hydroxymethyltransferase OS...	401	2e-113	347	47	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.

records

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Total records:

829

61 - 90

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