FGC: Single Locus Summary

UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YLR058C

Length:

469

Number of sequences:

5887

Description:

YLR058C SHM2 SGDID:S000004048, Chr XII from 259401-257992, Genome Release 64-1-1, reverse complement, Verified ORF, "Cytosolic serine hydroxymethyltransferase, converts serine to glycine plus 5,10 methylenetetrahydrofolate; major isoform involved in generating precursors for purine, pyrimidine, amino acid, and lipid biosynthesis"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
121	Q92QU6	431	GLYA1_RHIME Serine hydroxymethyltransferase 1...	413	4e-112	344	45	60	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
122	C1DEQ3	417	GLYA_AZOVD Serine hydroxymethyltransferase OS...	401	4e-112	343	46	64	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
123	Q5ZXK6	417	GLYA_LEGPH Serine hydroxymethyltransferase OS...	390	5e-112	343	47	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
124	Q5X722	417	GLYA_LEGPA Serine hydroxymethyltransferase OS...	390	5e-112	343	47	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
125	Q6G3L3	437	GLYA_BARHE Serine hydroxymethyltransferase OS...	464	5e-112	344	42	58	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
126	Q1GGA4	431	GLYA_SILST Serine hydroxymethyltransferase OS...	411	5e-112	344	46	61	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
127	A4SJN4	417	GLYA_AERS4 Serine hydroxymethyltransferase OS...	401	6e-112	343	45	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
128	Q086C9	417	GLYA_SHEFN Serine hydroxymethyltransferase OS...	402	6e-112	343	46	64	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
129	A5IGI2	417	GLYA_LEGPC Serine hydroxymethyltransferase OS...	390	6e-112	343	47	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
130	A1SUU0	421	GLYA_PSYIN Serine hydroxymethyltransferase OS...	402	6e-112	343	44	62	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
131	Q183G0	414	GLYA_CLOD6 Serine hydroxymethyltransferase OS...	411	7e-112	343	45	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
132	A1WVG6	416	GLYA_HALHL Serine hydroxymethyltransferase OS...	397	1e-111	343	46	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
133	Q5KUI2	412	GLYA_GEOKA Serine hydroxymethyltransferase OS...	430	1e-111	342	44	62	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
134	A1BE30	440	GLYA_CHLPD Serine hydroxymethyltransferase OS...	423	1e-111	343	45	60	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
135	B9LKK8	419	GLYA_CHLSY Serine hydroxymethyltransferase OS...	430	1e-111	343	42	60	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
136	A9WI58	419	GLYA_CHLAA Serine hydroxymethyltransferase OS...	433	1e-111	343	42	60	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
137	B2V398	411	GLYA_CLOBA Serine hydroxymethyltransferase OS...	406	1e-111	342	44	64	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
138	Q607U4	418	GLYA_METCA Serine hydroxymethyltransferase OS...	397	1e-111	342	46	65	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
139	Q2RTB8	430	GLYA2_RHORT Serine hydroxymethyltransferase 2...	406	2e-111	343	46	60	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
140	A4ITJ9	412	GLYA_GEOTN Serine hydroxymethyltransferase OS...	403	2e-111	342	46	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
141	Q0K7W0	415	GLYA_CUPNH Serine hydroxymethyltransferase OS...	394	2e-111	342	48	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
142	B0CEI9	426	GLYA_ACAM1 Serine hydroxymethyltransferase OS...	431	2e-111	342	42	61	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
143	B9M0W5	415	GLYA_GEOSF Serine hydroxymethyltransferase OS...	407	2e-111	342	45	62	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
144	Q0AUC3	415	GLYA_SYNWW Serine hydroxymethyltransferase OS...	405	2e-111	342	45	62	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
145	Q6MLK1	415	GLYA_BDEBA Serine hydroxymethyltransferase OS...	409	2e-111	342	44	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
146	Q5WYH4	417	GLYA_LEGPL Serine hydroxymethyltransferase OS...	395	2e-111	342	47	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
147	Q73GC3	425	GLYA_WOLPM Serine hydroxymethyltransferase OS...	402	3e-111	342	46	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
148	Q8EBN8	417	GLYA_SHEON Serine hydroxymethyltransferase OS...	402	3e-111	342	46	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
149	B2V9M1	422	GLYA_SULSY Serine hydroxymethyltransferase OS...	410	3e-111	342	46	62	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
150	Q4K4P6	417	GLYA2_PSEF5 Serine hydroxymethyltransferase 2...	385	3e-111	342	46	65	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
151	Q48CP3	417	GLYA2_PSE14 Serine hydroxymethyltransferase 2...	385	3e-111	341	47	64	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.

records

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Total records:

829

121 - 150

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