UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YLR047C

Length:

686

Number of sequences:

5887

Description:

YLR047C FRE8 SGDID:S000004037, Chr XII from 241407-239347, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein with sequence similarity to iron/copper reductases, involved in iron homeostasis; deletion mutant has iron deficiency/accumulation growth defects; expression increased in the absence of copper-responsive transcription factor Mac1p"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	Q12209	686	FRE8_YEAST Probable ferric reductase transmem...	686	0	1417	100	100	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0000293; F:ferric-chelate reductase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.
									GO:0006875; P:cellular metal ion homeostasis; IMP:SGD.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
2	Q75CQ8	686	FRE8_ASHGO Probable ferric reductase transmem...	674	1e-177	530	43	62	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0000293; F:ferric-chelate reductase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
3	Q6C188	525	AIM14_YARLI Probable metalloreductase AIM14 O...	508	4e-48	181	28	45	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
4	C5M5S1	551	AIM14_CANTT Probable metalloreductase AIM14 O...	32	1.1	36.2	41	56	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
5	A3LN69	524	AIM14_PICST Probable metalloreductase AIM14 O...	453	1e-35	144	29	45	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
6	Q6BM09	512	AIM14_DEBHA Probable metalloreductase AIM14 O...	35	1.4	35.8	34	63	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
7	P53109	570	AIM14_YEAST Probable metalloreductase AIM14 O...	441	5e-33	137	30	47	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
8	C8Z891	576	AIM14_YEAS8 Probable metalloreductase AIM14 O...	468	6e-33	137	30	46	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
9	Q6CIY2	508	AIM14_KLULA Probable metalloreductase AIM14 O...	384	1e-32	135	29	49	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
10	C5E398	533	AIM14_LACTC Probable metalloreductase AIM14 O...	352	2e-32	135	32	47	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
11	A6ZU25	570	AIM14_YEAS7 Probable metalloreductase AIM14 O...	468	2e-32	135	30	46	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
12	C7GPP6	570	AIM14_YEAS2 Probable metalloreductase AIM14 O...	467	2e-32	135	30	46	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
13	B3LHL3	570	AIM14_YEAS1 Probable metalloreductase AIM14 O...	441	2e-32	135	30	47	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
14	Q754F4	516	AIM14_ASHGO Probable metalloreductase AIM14 O...	353	3e-31	132	31	50	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
15	B9WB34	537	AIM14_CANDC Probable metalloreductase AIM14 O...	36	0.19	38.5	42	56	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
16	A5DE11	482	AIM14_PICGU Probable metalloreductase AIM14 O...	442	2e-30	128	26	47	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
17	A7TQE6	519	AIM14_VANPO Probable metalloreductase AIM14 O...	41	0.36	37.7	34	54	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
18	C4Y9R6	513	AIM14_CLAL4 Probable metalloreductase AIM14 O...	427	5e-28	122	27	45	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
19	C5E4F2	526	AIM14_ZYGRC Probable metalloreductase AIM14 O...	49	0.76	36.6	35	51	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
20	O94727	564	FRP2_SCHPO Ferric/cupric reductase transmembr...	435	0.00000001	61.6	22	38	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; ISS:PomBase.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0000293; F:ferric-chelate reductase activity; ISS:PomBase.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.
									GO:0015677; P:copper ion import; ISS:PomBase.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0034755; P:iron ion transmembrane transport; ISS:PomBase.::GO:0015891; P:siderophore transport; ISS:PomBase.
21	Q04800	564	FRP1_SCHPO Ferric reductase transmembrane com...	233	0.000002	54.3	23	45	GO:0005783; C:endoplasmic reticulum; IDA:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; ISS:PomBase.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0000293; F:ferric-chelate reductase activity; TAS:PomBase.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.
									GO:0015677; P:copper ion import; ISS:PomBase.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0033215; P:iron assimilation by reduction and transport; IMP:PomBase.::GO:0034755; P:iron ion transmembrane transport; IMP:PomBase.
22	P36033	711	FRE2_YEAST Ferric/cupric reductase transmembr...	250	0.0007	46.6	22	42	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:SGD.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0000293; F:ferric-chelate reductase activity; IDA:SGD.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.
									GO:0015677; P:copper ion import; IDA:SGD.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.::GO:0006826; P:iron ion transport; IDA:SGD.
23	P78588	669	FREL_CANAX Probable ferric reductase transmem...	400	0.003	44.3	24	38	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0000293; F:ferric-chelate reductase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
24	Q12473	712	FRE6_YEAST Ferric reductase transmembrane com...	151	0.011	42.7	22	46	GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0000293; F:ferric-chelate reductase activity; IMP:SGD.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.
									GO:0015677; P:copper ion import; IGI:SGD.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006880; P:intracellular sequestering of iron ion; IMP:SGD.
25	Q8VY13	728	FRO8_ARATH Ferric reduction oxidase 8, mitoch...	132	0.038	40.8	28	51	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0000293; F:ferric-chelate reductase activity; IDA:TAIR.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
26	Q54F44	1142	NOXC_DICDI Superoxide-generating NADPH oxidas...	224	0.11	39.7	21	41	GO:0043020; C:NADPH oxidase complex; ISS:dictyBase.
									GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; ISS:dictyBase.::GO:0020037; F:heme binding; ISS:dictyBase.::GO:0050661; F:NADP binding; ISS:dictyBase.::GO:0016175; F:superoxide-generating NADPH oxidase activity; ISS:dictyBase.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0030587; P:sorocarp development; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:dictyBase.::GO:0042554; P:superoxide anion generation; ISS:dictyBase.::GO:0006810; P:transport; IEA:UniProtKB-KW.
27	P53746	719	FRE4_YEAST Ferric reductase transmembrane com...	182	0.12	39.3	26	42	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IMP:SGD.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0000293; F:ferric-chelate reductase activity; IMP:SGD.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0015891; P:siderophore transport; IMP:SGD.
28	P32791	686	FRE1_YEAST Ferric/cupric reductase transmembr...	126	0.53	37.4	19	43	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0000293; F:ferric-chelate reductase activity; IDA:SGD.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.
									GO:0015677; P:copper ion import; IDA:SGD.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.::GO:0006826; P:iron ion transport; IDA:SGD.
29	Q08905	711	FRE3_YEAST Ferric reductase transmembrane com...	251	0.56	37.4	21	41	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:SGD.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0015891; P:siderophore transport; IMP:SGD.
30	Q08908	694	FRE5_YEAST Ferric reductase transmembrane com...	131	0.76	36.6	25	47	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
31	Q9FLW2	707	FRO5_ARATH Ferric reduction oxidase 5 OS=Arab...	90	1.2	36.2	28	51	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0000293; F:ferric-chelate reductase activity; IDA:TAIR.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.
									GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.

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