rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
121 | Q8XP76 | 639 | IOLD_CLOPE 3D-(3,5/4)-trihydroxycyclohexane-1... | 320 | 0.00001 | 52 | 23 | 38 | | | | | | | | | | | GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro. | | | | | | | | | | GO:0019310; P:inositol catabolic process; IEA:InterPro. | 122 | Q8Y9Y1 | 638 | IOLD_LISMO 3D-(3,5/4)-trihydroxycyclohexane-1... | 351 | 0.00001 | 51.6 | 21 | 39 | | | | | | | | | | | GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro. | | | | | | | | | | GO:0019310; P:inositol catabolic process; IEA:InterPro. | 123 | Q898E8 | 644 | IOLD_CLOTE 3D-(3,5/4)-trihydroxycyclohexane-1... | 315 | 0.00001 | 51.6 | 22 | 39 | | | | | | | | | | | GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro. | | | | | | | | | | GO:0019310; P:inositol catabolic process; IEA:InterPro. | 124 | Q65D03 | 637 | IOLD_BACLD 3D-(3,5/4)-trihydroxycyclohexane-1... | 375 | 0.00002 | 51.2 | 23 | 37 | | | | | | | | | | | GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro. | | | | | | | | | | GO:0019310; P:inositol catabolic process; IEA:InterPro. | 125 | Q723S8 | 638 | IOLD_LISMF 3D-(3,5/4)-trihydroxycyclohexane-1... | 384 | 0.00002 | 50.8 | 23 | 39 | | | | | | | | | | | GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro. | | | | | | | | | | GO:0019310; P:inositol catabolic process; IEA:InterPro. | 126 | Q92EQ4 | 638 | IOLD_LISIN 3D-(3,5/4)-trihydroxycyclohexane-1... | 521 | 0.00003 | 50.8 | 20 | 36 | | | | | | | | | | | GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro. | | | | | | | | | | GO:0019310; P:inositol catabolic process; IEA:InterPro. | 127 | B2V4K0 | 643 | IOLD_CLOBA 3D-(3,5/4)-trihydroxycyclohexane-1... | 278 | 0.00006 | 49.3 | 25 | 39 | | | | | | | | | | | GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro. | | | | | | | | | | GO:0019310; P:inositol catabolic process; IEA:InterPro. | 128 | Q9KAG9 | 637 | IOLD_BACHD 3D-(3,5/4)-trihydroxycyclohexane-1... | 391 | 0.0001 | 48.9 | 21 | 37 | | | | | | | | | | | GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro. | | | | | | | | | | GO:0019310; P:inositol catabolic process; IEA:InterPro. | 129 | Q6NV04 | 621 | ILVBL_DANRE Acetolactate synthase-like protei... | 518 | 0.0001 | 48.9 | 21 | 37 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 130 | P0AFI0 | 564 | OXC_ECOLI Probable oxalyl-CoA decarboxylase O... | 291 | 0.0001 | 48.5 | 26 | 42 | | | | | | | | | | | GO:0043531; F:ADP binding; IDA:EcoCyc.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0008949; F:oxalyl-CoA decarboxylase activity; IDA:EcoCyc.::GO:0030976; F:thiamine pyrophosphate binding; IDA:EcoCyc. | | | | | | | | | | GO:0033611; P:oxalate catabolic process; IEA:InterPro. | 131 | P0AFI1 | 564 | OXC_ECO57 Probable oxalyl-CoA decarboxylase O... | 291 | 0.0001 | 48.5 | 26 | 42 | | | | | | | | | | | GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0008949; F:oxalyl-CoA decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro. | | | | | | | | | | GO:0033611; P:oxalate catabolic process; IEA:InterPro. | 132 | Q5KYR0 | 644 | IOLD_GEOKA 3D-(3,5/4)-trihydroxycyclohexane-1... | 262 | 0.0002 | 48.1 | 24 | 41 | | | | | | | | | | | GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro. | | | | | | | | | | GO:0019310; P:inositol catabolic process; IEA:InterPro. | 133 | A7ZAH8 | 637 | IOLD_BACA2 3D-(3,5/4)-trihydroxycyclohexane-1... | 380 | 0.0002 | 48.1 | 21 | 38 | | | | | | | | | | | GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro. | | | | | | | | | | GO:0019310; P:inositol catabolic process; IEA:InterPro. | 134 | P42415 | 637 | IOLD_BACSU 3D-(3,5/4)-trihydroxycyclohexane-1... | 413 | 0.0004 | 47 | 21 | 37 | | | | | | | | | | | GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro. | | | | | | | | | | GO:0019310; P:inositol catabolic process; IEA:InterPro. | 135 | P07003 | 572 | POXB_ECOLI Pyruvate dehydrogenase [ubiquinone... | 504 | 0.0005 | 46.6 | 19 | 38 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0052737; F:pyruvate dehydrogenase (quinone) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro. | | | | | | | | | | | 136 | B2TJ86 | 643 | IOLD_CLOBB 3D-(3,5/4)-trihydroxycyclohexane-1... | 278 | 0.005 | 43.5 | 24 | 38 | | | | | | | | | | | GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro. | | | | | | | | | | GO:0019310; P:inositol catabolic process; IEA:InterPro. | 137 | O61856 | 640 | ILVBL_CAEEL Acetolactate synthase-like protei... | 313 | 0.025 | 41.2 | 25 | 38 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase. | 138 | Q54970 | 591 | POXB_STRPN Pyruvate oxidase OS=Streptococcus ... | 508 | 0.031 | 40.8 | 21 | 39 | | | | | | | | | | | GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0047112; F:pyruvate oxidase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro. | | | | | | | | | | | 139 | Q04789 | 570 | ILVX_BACSU Acetolactate synthase OS=Bacillus ... | 484 | 0.044 | 40.4 | 20 | 39 | | | | | | | | | | | GO:0003984; F:acetolactate synthase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro. | | | | | | | | | | GO:0045151; P:acetoin biosynthetic process; IEA:UniProtKB-KW. | 140 | Q05326 | 106 | PDC2_MAIZE Pyruvate decarboxylase isozyme 2 O... | 38 | 0.089 | 36.6 | 47 | 66 | | | | | | | | | | | GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro. | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 141 | O05031 | 265 | Y737_HAEIN Putative uncharacterized protein H... | 98 | 0.1 | 38.5 | 30 | 48 | | | | | | | | | | | GO:0003984; F:acetolactate synthase activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016829; F:lyase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009082; P:branched chain family amino acid biosynthetic process; IEA:InterPro. | 142 | Q1AS21 | 574 | MEND_RUBXD 2-succinyl-5-enolpyruvyl-6-hydroxy... | 177 | 0.4 | 37.4 | 27 | 41 | | | | | | | | | | | GO:0070204; F:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009234; P:menaquinone biosynthetic process; IEA:UniProtKB-KW. | 143 | Q45072 | 352 | TFTE_BURCE Maleylacetate reductase OS=Burkhol... | 112 | 0.47 | 36.6 | 29 | 44 | | | | | | | | | | | GO:0018506; F:maleylacetate reductase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW. | 144 | Q9Y7M1 | 568 | YGK4_SCHPO Putative 2-hydroxyacyl-CoA lyase O... | 156 | 0.58 | 36.6 | 27 | 46 | GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0016831; F:carboxy-lyase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro. | | | | | | | | | | | 145 | A5UPB5 | 583 | MEND_ROSS1 2-succinyl-5-enolpyruvyl-6-hydroxy... | 259 | 0.6 | 36.6 | 21 | 38 | | | | | | | | | | | GO:0070204; F:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009234; P:menaquinone biosynthetic process; IEA:UniProtKB-KW. | 146 | P58416 | 188 | COME_METJA Sulfopyruvate decarboxylase subuni... | 133 | 0.77 | 35.4 | 27 | 44 | | | | | | | | | | | GO:0050545; F:sulfopyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro. | | | | | | | | | | GO:0019295; P:coenzyme M biosynthetic process; IEA:UniProtKB-KW. | 147 | A1U0A9 | 644 | MACB_MARAV Macrolide export ATP-binding/perme... | 104 | 1.8 | 35 | 30 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.::GO:0016820; F:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; IEA:InterPro. | | | | | | | | | | GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW. | 148 | A4W9J8 | 441 | ASTB_ENT38 N-succinylarginine dihydrolase OS=... | 71 | 3.6 | 33.9 | 28 | 49 | | | | | | | | | | | GO:0009015; F:N-succinylarginine dihydrolase activity; IEA:EC. | | | | | | | | | | GO:0006525; P:arginine metabolic process; IEA:UniProtKB-KW. | 149 | B3EMZ5 | 581 | MEND_CHLPB 2-succinyl-5-enolpyruvyl-6-hydroxy... | 86 | 4.4 | 33.9 | 29 | 48 | | | | | | | | | | | GO:0070204; F:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009234; P:menaquinone biosynthetic process; IEA:UniProtKB-KW. | 150 | Q5S007 | 2527 | LRRK2_HUMAN Leucine-rich repeat serine/threon... | 41 | 4.8 | 33.9 | 37 | 61 | GO:0032473; C:external side of mitochondrial outer membrane; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0043005; C:neuron projection; IDA:BHF-UCL.::GO:0043025; C:neuronal cell body; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0034211; F:GTP-dependent protein kinase activity; IMP:UniProtKB.::GO:0005096; F:GTPase activator activity; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:BHF-UCL.::GO:0004708; F:MAP kinase kinase activity; IDA:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0017048; F:Rho GTPase binding; IPI:BHF-UCL.::GO:0015631; F:tubulin binding; IDA:BHF-UCL. | | | | | | | | | | GO:0000186; P:activation of MAPKK activity; IDA:BHF-UCL.::GO:0008340; P:determination of adult lifespan; IMP:BHF-UCL.::GO:0035640; P:exploration behavior; IMP:BHF-UCL.::GO:0048312; P:intracellular distribution of mitochondria; IMP:BHF-UCL.::GO:2000173; P:negative regulation of branching morphogenesis of a nerve; IMP:BHF-UCL.::GO:0061002; P:negative regulation of dendritic spine morphogenesis; IMP:BHF-UCL.::GO:0007406; P:negative regulation of neuroblast proliferation; IMP:BHF-UCL.::GO:0014043; P:negative regulation of neuron maturation; IMP:BHF-UCL.::GO:0007528; P:neuromuscular junction development; IMP:BHF-UCL.::GO:0070997; P:neuron death; IMP:BHF-UCL.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.::GO:0010508; P:positive regulation of autophagy; ISS:BHF-UCL.::GO:0060161; P:positive regulation of dopamine receptor signaling pathway; IMP:BHF-UCL.::GO:0043068; P:positive regulation of programmed cell death; IDA:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:BHF-UCL.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0035564; P:regulation of kidney size; ISS:BHF-UCL.::GO:0040012; P:regulation of locomotion; IMP:BHF-UCL.::GO:0042391; P:regulation of membrane potential; IMP:BHF-UCL.::GO:0006979; P:response to oxidative stress; IMP:BHF-UCL.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0022028; P:tangential migration from the subventricular zone to the olfactory bulb; IMP:BHF-UCL. |