Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR044C
Length:
563
Number of sequences:
5887
Description:
YLR044C PDC1 SGDID:S000004034, Chr XII from 234081-232390, Genome Release 64-1-1, reverse complement, Verified ORF, "Major of three pyruvate decarboxylase isozymes, key enzyme in alcoholic fermentation, decarboxylates pyruvate to acetaldehyde; subject to glucose-, ethanol-, and autoregulation; involved in amino acid catabolism"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121Q8XP76    639   IOLD_CLOPE 3D-(3,5/4)-trihydroxycyclohexane-1...3200.00001     52     23     38
GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
GO:0019310; P:inositol catabolic process; IEA:InterPro.
122Q8Y9Y1    638   IOLD_LISMO 3D-(3,5/4)-trihydroxycyclohexane-1...3510.00001     51.6     21     39
GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0019310; P:inositol catabolic process; IEA:InterPro.
123Q898E8    644   IOLD_CLOTE 3D-(3,5/4)-trihydroxycyclohexane-1...3150.00001     51.6     22     39
GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0019310; P:inositol catabolic process; IEA:InterPro.
124Q65D03    637   IOLD_BACLD 3D-(3,5/4)-trihydroxycyclohexane-1...3750.00002     51.2     23     37
GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
GO:0019310; P:inositol catabolic process; IEA:InterPro.
125Q723S8    638   IOLD_LISMF 3D-(3,5/4)-trihydroxycyclohexane-1...3840.00002     50.8     23     39
GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0019310; P:inositol catabolic process; IEA:InterPro.
126Q92EQ4    638   IOLD_LISIN 3D-(3,5/4)-trihydroxycyclohexane-1...5210.00003     50.8     20     36
GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0019310; P:inositol catabolic process; IEA:InterPro.
127B2V4K0    643   IOLD_CLOBA 3D-(3,5/4)-trihydroxycyclohexane-1...2780.00006     49.3     25     39
GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
GO:0019310; P:inositol catabolic process; IEA:InterPro.
128Q9KAG9    637   IOLD_BACHD 3D-(3,5/4)-trihydroxycyclohexane-1...3910.0001     48.9     21     37
GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
GO:0019310; P:inositol catabolic process; IEA:InterPro.
129Q6NV04    621   ILVBL_DANRE Acetolactate synthase-like protei...5180.0001     48.9     21     37GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
130P0AFI0    564   OXC_ECOLI Probable oxalyl-CoA decarboxylase O...2910.0001     48.5     26     42
GO:0043531; F:ADP binding; IDA:EcoCyc.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0008949; F:oxalyl-CoA decarboxylase activity; IDA:EcoCyc.::GO:0030976; F:thiamine pyrophosphate binding; IDA:EcoCyc.
GO:0033611; P:oxalate catabolic process; IEA:InterPro.
131P0AFI1    564   OXC_ECO57 Probable oxalyl-CoA decarboxylase O...2910.0001     48.5     26     42
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0008949; F:oxalyl-CoA decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0033611; P:oxalate catabolic process; IEA:InterPro.
132Q5KYR0    644   IOLD_GEOKA 3D-(3,5/4)-trihydroxycyclohexane-1...2620.0002     48.1     24     41
GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
GO:0019310; P:inositol catabolic process; IEA:InterPro.
133A7ZAH8    637   IOLD_BACA2 3D-(3,5/4)-trihydroxycyclohexane-1...3800.0002     48.1     21     38
GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
GO:0019310; P:inositol catabolic process; IEA:InterPro.
134P42415    637   IOLD_BACSU 3D-(3,5/4)-trihydroxycyclohexane-1...4130.0004     47     21     37
GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
GO:0019310; P:inositol catabolic process; IEA:InterPro.
135P07003    572   POXB_ECOLI Pyruvate dehydrogenase [ubiquinone...5040.0005     46.6     19     38GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0052737; F:pyruvate dehydrogenase (quinone) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
136B2TJ86    643   IOLD_CLOBB 3D-(3,5/4)-trihydroxycyclohexane-1...2780.005     43.5     24     38
GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
GO:0019310; P:inositol catabolic process; IEA:InterPro.
137O61856    640   ILVBL_CAEEL Acetolactate synthase-like protei...3130.025     41.2     25     38GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.
138Q54970    591   POXB_STRPN Pyruvate oxidase OS=Streptococcus ...5080.031     40.8     21     39
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0047112; F:pyruvate oxidase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
139Q04789    570   ILVX_BACSU Acetolactate synthase OS=Bacillus ...4840.044     40.4     20     39
GO:0003984; F:acetolactate synthase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0045151; P:acetoin biosynthetic process; IEA:UniProtKB-KW.
140Q05326    106   PDC2_MAIZE Pyruvate decarboxylase isozyme 2 O...380.089     36.6     47     66
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
141O05031    265   Y737_HAEIN Putative uncharacterized protein H...980.1     38.5     30     48
GO:0003984; F:acetolactate synthase activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016829; F:lyase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0009082; P:branched chain family amino acid biosynthetic process; IEA:InterPro.
142Q1AS21    574   MEND_RUBXD 2-succinyl-5-enolpyruvyl-6-hydroxy...1770.4     37.4     27     41
GO:0070204; F:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0009234; P:menaquinone biosynthetic process; IEA:UniProtKB-KW.
143Q45072    352   TFTE_BURCE Maleylacetate reductase OS=Burkhol...1120.47     36.6     29     44
GO:0018506; F:maleylacetate reductase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
144Q9Y7M1    568   YGK4_SCHPO Putative 2-hydroxyacyl-CoA lyase O...1560.58     36.6     27     46GO:0005829; C:cytosol; IDA:PomBase.
GO:0016831; F:carboxy-lyase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
145A5UPB5    583   MEND_ROSS1 2-succinyl-5-enolpyruvyl-6-hydroxy...2590.6     36.6     21     38
GO:0070204; F:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0009234; P:menaquinone biosynthetic process; IEA:UniProtKB-KW.
146P58416    188   COME_METJA Sulfopyruvate decarboxylase subuni...1330.77     35.4     27     44
GO:0050545; F:sulfopyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0019295; P:coenzyme M biosynthetic process; IEA:UniProtKB-KW.
147A1U0A9    644   MACB_MARAV Macrolide export ATP-binding/perme...1041.8     35     30     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.::GO:0016820; F:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; IEA:InterPro.
GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
148A4W9J8    441   ASTB_ENT38 N-succinylarginine dihydrolase OS=...713.6     33.9     28     49
GO:0009015; F:N-succinylarginine dihydrolase activity; IEA:EC.
GO:0006525; P:arginine metabolic process; IEA:UniProtKB-KW.
149B3EMZ5    581   MEND_CHLPB 2-succinyl-5-enolpyruvyl-6-hydroxy...864.4     33.9     29     48
GO:0070204; F:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0009234; P:menaquinone biosynthetic process; IEA:UniProtKB-KW.
150Q5S007    2527   LRRK2_HUMAN Leucine-rich repeat serine/threon...414.8     33.9     37     61GO:0032473; C:external side of mitochondrial outer membrane; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0043005; C:neuron projection; IDA:BHF-UCL.::GO:0043025; C:neuronal cell body; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0034211; F:GTP-dependent protein kinase activity; IMP:UniProtKB.::GO:0005096; F:GTPase activator activity; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:BHF-UCL.::GO:0004708; F:MAP kinase kinase activity; IDA:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0017048; F:Rho GTPase binding; IPI:BHF-UCL.::GO:0015631; F:tubulin binding; IDA:BHF-UCL.
GO:0000186; P:activation of MAPKK activity; IDA:BHF-UCL.::GO:0008340; P:determination of adult lifespan; IMP:BHF-UCL.::GO:0035640; P:exploration behavior; IMP:BHF-UCL.::GO:0048312; P:intracellular distribution of mitochondria; IMP:BHF-UCL.::GO:2000173; P:negative regulation of branching morphogenesis of a nerve; IMP:BHF-UCL.::GO:0061002; P:negative regulation of dendritic spine morphogenesis; IMP:BHF-UCL.::GO:0007406; P:negative regulation of neuroblast proliferation; IMP:BHF-UCL.::GO:0014043; P:negative regulation of neuron maturation; IMP:BHF-UCL.::GO:0007528; P:neuromuscular junction development; IMP:BHF-UCL.::GO:0070997; P:neuron death; IMP:BHF-UCL.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.::GO:0010508; P:positive regulation of autophagy; ISS:BHF-UCL.::GO:0060161; P:positive regulation of dopamine receptor signaling pathway; IMP:BHF-UCL.::GO:0043068; P:positive regulation of programmed cell death; IDA:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:BHF-UCL.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0035564; P:regulation of kidney size; ISS:BHF-UCL.::GO:0040012; P:regulation of locomotion; IMP:BHF-UCL.::GO:0042391; P:regulation of membrane potential; IMP:BHF-UCL.::GO:0006979; P:response to oxidative stress; IMP:BHF-UCL.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0022028; P:tangential migration from the subventricular zone to the olfactory bulb; IMP:BHF-UCL.
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