Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR043C
Length:
103
Number of sequences:
5887
Description:
YLR043C TRX1 SGDID:S000004033, Chr XII from 232013-231702, Genome Release 64-1-1, reverse complement, Verified ORF, "Cytoplasmic thioredoxin isoenzyme of the thioredoxin system which protects cells against oxidative and reductive stress, forms LMA1 complex with Pbi2p, acts as a cofactor for Tsa1p, required for ER-Golgi transport and vacuole inheritance"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
211Q53LQ0    512   PDI11_ORYSJ Protein disulfide isomerase-like ...310.006     38.1     45     68GO:0005788; C:endoplasmic reticulum lumen; IDA:UniProtKB.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0034975; P:protein folding in endoplasmic reticulum; IMP:UniProtKB.
212P38661    364   PDIA6_MEDSA Probable protein disulfide-isomer...780.0000000004     59.3     38     50GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
213Q9ZPH2    488   GRS17_ARATH Monothiol glutaredoxin-S17 OS=Ara...1020.0000000003     60.1     25     55GO:0005829; C:cytosol; IDA:TAIR.
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0009926; P:auxin polar transport; IMP:TAIR.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0072593; P:reactive oxygen species metabolic process; IMP:TAIR.::GO:0051726; P:regulation of cell cycle; IEP:TAIR.::GO:0009408; P:response to heat; IMP:TAIR.
214Q3T0L2    406   ERP44_BOVIN Endoplasmic reticulum resident pr...770.0000000003     59.7     38     60GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
215Q9JLZ1    337   GLRX3_RAT Glutaredoxin-3 OS=Rattus norvegicus...800.0000000004     58.9     30     64GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0005080; F:protein kinase C binding; IDA:RGD.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
216Q942L2    371   PDI22_ORYSJ Protein disulfide isomerase-like ...800.0000000006     58.5     40     58GO:0005783; C:endoplasmic reticulum; IEA:InterPro.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
217Q94F09    440   PDI52_ARATH Protein disulfide-isomerase 5-2 O...820.0000000005     59.3     40     57GO:0005783; C:endoplasmic reticulum; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0009505; C:plant-type cell wall; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; ISS:TAIR.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
218P29828    512   PDI_MEDSA Protein disulfide-isomerase OS=Medi...310.004     38.5     42     68GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
219Q9CQM9    337   GLRX3_MOUSE Glutaredoxin-3 OS=Mus musculus (M...800.0000000005     58.9     30     64GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IDA:UniProtKB.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0010614; P:negative regulation of cardiac muscle hypertrophy; IMP:UniProtKB.::GO:0002026; P:regulation of the force of heart contraction; IMP:UniProtKB.
220P52589    515   PDI_WHEAT Protein disulfide-isomerase OS=Trit...870.005     38.5     31     51GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
221P34329    618   PDIA4_CAEEL Probable protein disulfide-isomer...810.16     33.9     27     43GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0030968; P:endoplasmic reticulum unfolded protein response; IEP:WormBase.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.
222P05307    510   PDIA1_BOVIN Protein disulfide-isomerase OS=Bo...660.00002     45.4     35     52GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; ISS:AgBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0004656; F:procollagen-proline 4-dioxygenase activity; ISS:AgBase.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0018401; P:peptidyl-proline hydroxylation to 4-hydroxy-L-proline; ISS:AgBase.
223O22263    361   PDI21_ARATH Protein disulfide-isomerase like ...760.00000005     53.1     39     53GO:0005783; C:endoplasmic reticulum; IDA:TAIR.::GO:0009505; C:plant-type cell wall; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; ISS:TAIR.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0009567; P:double fertilization forming a zygote and endosperm; IMP:TAIR.::GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.::GO:0009553; P:embryo sac development; IMP:TAIR.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0048868; P:pollen tube development; IMP:TAIR.::GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0034976; P:response to endoplasmic reticulum stress; IEP:TAIR.
224P73263    109   THIO2_SYNY3 Thioredoxin-like protein slr1139 ...860.0000000007     55.8     37     57
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
225Q58DA7    334   GLRX3_BOVIN Glutaredoxin-3 OS=Bos taurus (Bov...840.0000000009     58.2     29     63GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0010614; P:negative regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0002026; P:regulation of the force of heart contraction; ISS:UniProtKB.
226Q9D1Q6    406   ERP44_MOUSE Endoplasmic reticulum resident pr...810.000000001     58.2     36     57GO:0005788; C:endoplasmic reticulum lumen; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0003756; F:protein disulfide isomerase activity; ISS:UniProtKB.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0009100; P:glycoprotein metabolic process; ISS:UniProtKB.::GO:0006457; P:protein folding; ISS:UniProtKB.::GO:0006986; P:response to unfolded protein; ISS:UniProtKB.
227O34357    107   YTPP_BACSU Thioredoxin-like protein ytpP OS=B...860.000000002     54.3     27     52
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
228P54399    496   PDI_DROME Protein disulfide-isomerase OS=Dros...860.00000008     52.8     35     59GO:0060187; C:cell pole; IDA:FlyBase.::GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IDA:FlyBase.::GO:0045169; C:fusome; IDA:FlyBase.::GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0043025; C:neuronal cell body; IDA:FlyBase.::GO:0005635; C:nuclear envelope; IDA:FlyBase.::GO:0048471; C:perinuclear region of cytoplasm; IDA:FlyBase.::GO:0005791; C:rough endoplasmic reticulum; IDA:FlyBase.::GO:0070732; C:spindle envelope; IDA:FlyBase.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
229Q9C5C5    204   TRL4_ARATH Thioredoxin-like 4, chloroplastic ...920.000000004     54.7     38     51GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
230Q9BS26    406   ERP44_HUMAN Endoplasmic reticulum resident pr...770.000000004     56.6     36     58GO:0005788; C:endoplasmic reticulum lumen; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IDA:UniProtKB.
GO:0003756; F:protein disulfide isomerase activity; IDA:UniProtKB.
GO:0045454; P:cell redox homeostasis; TAS:UniProtKB.::GO:0009100; P:glycoprotein metabolic process; IDA:UniProtKB.::GO:0006457; P:protein folding; IDA:UniProtKB.::GO:0006986; P:response to unfolded protein; IDA:UniProtKB.
231O13811    359   PDI2_SCHPO Protein disulfide-isomerase C17H9....720.000000009     55.5     36     57GO:0005783; C:endoplasmic reticulum; ISS:PomBase.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IMP:PomBase.::GO:0015035; F:protein disulfide oxidoreductase activity; IMP:PomBase.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0034599; P:cellular response to oxidative stress; IMP:PomBase.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006457; P:protein folding; IMP:PomBase.
232P32642    244   GLRX4_YEAST Monothiol glutaredoxin-4 OS=Sacch...860.000000005     55.1     31     58GO:0005634; C:nucleus; IGI:SGD.
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; IMP:SGD.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006879; P:cellular iron ion homeostasis; IGI:SGD.::GO:0034599; P:cellular response to oxidative stress; IMP:SGD.
233P09102    515   PDIA1_CHICK Protein disulfide-isomerase OS=Ga...690.000009     46.6     33     52GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
234Q2HWU2    510   PDIA1_MACFU Protein disulfide-isomerase OS=Ma...660.00001     46.6     35     53GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
235P07237    508   PDIA1_HUMAN Protein disulfide-isomerase OS=Ho...680.000007     47     35     51GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.::GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IDA:UniProtKB.::GO:0005576; C:extracellular region; NAS:UniProtKB.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0004656; F:procollagen-proline 4-dioxygenase activity; IDA:MGI.::GO:0003756; F:protein disulfide isomerase activity; TAS:ProtInc.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006629; P:lipid metabolic process; TAS:Reactome.::GO:0042157; P:lipoprotein metabolic process; TAS:Reactome.::GO:0018401; P:peptidyl-proline hydroxylation to 4-hydroxy-L-proline; IDA:MGI.
236Q5R5B6    508   PDIA1_PONAB Protein disulfide-isomerase OS=Po...680.000008     47     35     51GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
237P09103    509   PDIA1_MOUSE Protein disulfide-isomerase OS=Mu...660.00003     45.4     35     52GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
238Q8NBS9    432   TXND5_HUMAN Thioredoxin domain-containing pro...880.00003     45.1     35     43GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0043202; C:lysosomal lumen; TAS:Reactome.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0016853; F:isomerase activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0006916; P:anti-apoptosis; TAS:UniProtKB.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
239Q8VZT6    192   TRL32_ARATH Thioredoxin-like 3-2, chloroplast...750.000000008     53.5     35     63GO:0009570; C:chloroplast stroma; IDA:TAIR.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
240P52588    513   PDI_MAIZE Protein disulfide-isomerase OS=Zea ...630.007     37.7     35     56GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
241Q7JW12    271   TMX2_DROME Thioredoxin-related transmembrane ...950.000000008     54.7     33     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
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