Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR032W
Length:
1169
Number of sequences:
5887
Description:
YLR032W RAD5 SGDID:S000004022, Chr XII from 204991-208500, Genome Release 64-1-1, Verified ORF, "DNA helicase proposed to promote replication fork regression during postreplication repair by template switching; RING finger containing ubiquitin ligase; stimulates the synthesis of free and PCNA-bound polyubiquitin chains by Ubc13p-Mms2p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
511Q5PPX5    257   RN170_XENLA RING finger protein 170 OS=Xenopu...651.8     35.8     31     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
512Q8GUK7    243   RMA3_ARATH E3 ubiquitin-protein ligase RMA3 O...771.8     35.8     27     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
513A0JN86    255   PCGF5_BOVIN Polycomb group RING finger protei...561.8     35.8     30     54
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
514P38398    1863   BRCA1_HUMAN Breast cancer type 1 susceptibili...541.9     36.6     37     56GO:0070531; C:BRCA1-A complex; IDA:UniProtKB.::GO:0031436; C:BRCA1-BARD1 complex; IDA:UniProtKB.::GO:0008274; C:gamma-tubulin ring complex; NAS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:BHF-UCL.::GO:0030529; C:ribonucleoprotein complex; IDA:MGI.::GO:0001726; C:ruffle; IDA:BHF-UCL.
GO:0050681; F:androgen receptor binding; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IDA:MGI.::GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.::GO:0015631; F:tubulin binding; NAS:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:ProtInc.
GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.::GO:0006915; P:apoptotic process; TAS:UniProtKB.::GO:0071681; P:cellular response to indole-3-methanol; IDA:UniProtKB.::GO:0007059; P:chromosome segregation; IMP:UniProtKB.::GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; TAS:UniProtKB.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IDA:MGI.::GO:0000724; P:double-strand break repair via homologous recombination; IDA:HGNC.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:UniProtKB.::GO:0046600; P:negative regulation of centriole replication; NAS:UniProtKB.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; IMP:UniProtKB.::GO:0051573; P:negative regulation of histone H3-K9 methylation; IDA:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0071158; P:positive regulation of cell cycle arrest; IDA:BHF-UCL.::GO:0045739; P:positive regulation of DNA repair; IMP:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; IDA:BHF-UCL.::GO:2000617; P:positive regulation of histone H3-K9 acetylation; IDA:BHF-UCL.::GO:2000620; P:positive regulation of histone H4-K16 acetylation; IDA:BHF-UCL.::GO:0070512; P:positive regulation of histone H4-K20 methylation; IDA:BHF-UCL.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006301; P:postreplication repair; IDA:HGNC.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; IDA:UniProtKB.::GO:2000145; P:regulation of cell motility; IDA:BHF-UCL.::GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.::GO:0006359; P:regulation of transcription from RNA polymerase III promoter; TAS:UniProtKB.::GO:0010212; P:response to ionizing radiation; IMP:UniProtKB.::GO:0034446; P:substrate adhesion-dependent cell spreading; IDA:BHF-UCL.
515O60858    407   TRI13_HUMAN E3 ubiquitin-protein ligase TRIM1...771.9     36.2     32     48GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0097038; C:perinuclear endoplasmic reticulum; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IMP:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.::GO:0030433; P:ER-associated protein catabolic process; IDA:UniProtKB.::GO:0010942; P:positive regulation of cell death; IDA:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0016239; P:positive regulation of macroautophagy; IDA:UniProtKB.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0010332; P:response to gamma radiation; IEP:UniProtKB.
516Q8L829    552   ARI5_ARATH Probable E3 ubiquitin-protein liga...1162     36.2     27     46
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
517Q4I7N9    703   BRE1_GIBZE E3 ubiquitin-protein ligase BRE1 O...522     36.2     31     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
518Q6PGR9    477   TRI72_XENLA Tripartite motif-containing prote...522     36.2     37     58GO:0030659; C:cytoplasmic vesicle membrane; ISS:UniProtKB.::GO:0042383; C:sarcolemma; ISS:UniProtKB.
GO:0001786; F:phosphatidylserine binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; ISS:UniProtKB.::GO:0003012; P:muscle system process; ISS:UniProtKB.::GO:0001778; P:plasma membrane repair; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
519Q2HJ46    487   RNF8_BOVIN E3 ubiquitin-protein ligase RNF8 O...692     36.2     32     54GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; ISS:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
520Q59S50    727   DBP7_CANAL ATP-dependent RNA helicase DBP7 OS...752     36.2     36     47GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
521B2VG58    430   RHLB_ERWT9 ATP-dependent RNA helicase rhlB OS...1142.1     35.8     23     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
522Q9GKK8    1863   BRCA1_PANTR Breast cancer type 1 susceptibili...542.1     36.2     37     56GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB.::GO:0008274; C:gamma-tubulin ring complex; NAS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0015631; F:tubulin binding; NAS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; TAS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; TAS:UniProtKB.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0046600; P:negative regulation of centriole replication; NAS:UniProtKB.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; NAS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; TAS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.::GO:0006359; P:regulation of transcription from RNA polymerase III promoter; TAS:UniProtKB.
523Q9LUL6    204   ATL61_ARATH Putative RING-H2 finger protein A...622.2     35     31     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
524Q5M7V1    407   TRI13_RAT Tripartite motif-containing 13 OS=R...612.2     35.8     33     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
525Q6J6I8    1863   BRCA1_GORGO Breast cancer type 1 susceptibili...542.3     36.2     37     56GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.
526Q6J6I9    1863   BRCA1_MACMU Breast cancer type 1 susceptibili...542.3     36.2     37     54GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.
527Q86SE9    256   PCGF5_HUMAN Polycomb group RING finger protei...562.3     35.4     30     54GO:0005813; C:centrosome; IDA:LIFEdb.::GO:0031519; C:PcG protein complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
528Q9FKA7    617   ORTH1_ARATH E3 ubiquitin-protein ligase ORTHR...512.4     35.8     37     53GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0008327; F:methyl-CpG binding; IDA:TAIR.::GO:0010428; F:methyl-CpNpG binding; IDA:TAIR.::GO:0010429; F:methyl-CpNpN binding; IDA:TAIR.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0010424; P:DNA methylation on cytosine within a CG sequence; IMP:UniProtKB.::GO:0090309; P:positive regulation of methylation-dependent chromatin silencing; IMP:UniProtKB.::GO:0010228; P:vegetative to reproductive phase transition of meristem; IMP:TAIR.
529O74563    680   BRL2_SCHPO E3 ubiquitin-protein ligase brl2 O...1072.4     35.8     26     50GO:0005721; C:centromeric heterochromatin; IDA:PomBase.::GO:0033503; C:HULC complex; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006336; P:DNA replication-independent nucleosome assembly; TAS:PomBase.::GO:0071894; P:histone H2B conserved C-terminal lysine ubiquitination; IDA:PomBase.::GO:0051569; P:regulation of histone H3-K4 methylation; IMP:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEP:PomBase.
530Q9WUH5    489   TRI10_MOUSE Tripartite motif-containing prote...522.4     35.8     37     48GO:0005737; C:cytoplasm; IDA:MGI.
GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030218; P:erythrocyte differentiation; IDA:MGI.
531Q3UK78    256   PCGF5_MOUSE Polycomb group RING finger protei...562.4     35.4     30     54GO:0031519; C:PcG protein complex; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
532Q4WZJ6    418   RAD18_ASPFU Postreplication repair E3 ubiquit...522.4     35.8     31     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
533Q6LV34    972   RAPA_PHOPR RNA polymerase-associated protein ...1202.5     36.2     28     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
534Q7T3E6    324   BMI1B_DANRE Polycomb complex protein BMI-1-B ...742.5     35.4     26     46GO:0031519; C:PcG protein complex; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
535Q2KHN1    245   RN151_HUMAN RING finger protein 151 OS=Homo s...722.5     35     25     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
536Q9C8E1    622   ORTH4_ARATH Putative E3 ubiquitin-protein lig...512.5     35.8     37     53GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0008327; F:methyl-CpG binding; ISS:UniProtKB.::GO:0010428; F:methyl-CpNpG binding; ISS:UniProtKB.::GO:0010429; F:methyl-CpNpN binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0010424; P:DNA methylation on cytosine within a CG sequence; ISS:UniProtKB.
537Q1ACD5    494   TRIM5_SAGOE Tripartite motif-containing prote...552.5     35.8     35     45GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
538B5YY28    421   RHLB_ECO5E ATP-dependent RNA helicase rhlB OS...1502.6     35.8     21     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
539Q680I0    623   ORTH5_ARATH E3 ubiquitin-protein ligase ORTHR...512.6     35.8     37     53GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0008327; F:methyl-CpG binding; ISS:UniProtKB.::GO:0010428; F:methyl-CpNpG binding; ISS:UniProtKB.::GO:0010429; F:methyl-CpNpN binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0090309; P:positive regulation of methylation-dependent chromatin silencing; IMP:UniProtKB.
540Q5C8U1    494   TRIM5_SAGLB Tripartite motif-containing prote...552.6     35.8     35     45GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
541P0C8K8    552   ARI6_ARATH Putative E3 ubiquitin-protein liga...842.6     35.8     32     45
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
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