rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
451 | Q8WVD5 | 230 | RN141_HUMAN RING finger protein 141 OS=Homo s... | 52 | 0.78 | 36.6 | 37 | 50 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 452 | Q6IV57 | 230 | RN141_RAT RING finger protein 141 OS=Rattus n... | 52 | 0.8 | 36.6 | 37 | 50 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 453 | Q28DS3 | 257 | RN170_XENTR RING finger protein 170 OS=Xenopu... | 82 | 0.81 | 37 | 27 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 454 | Q9TST0 | 326 | BMI1_FELCA Polycomb complex protein BMI-1 OS=... | 74 | 0.82 | 37 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0031519; C:PcG protein complex; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 455 | Q60YN5 | 828 | BRE1_CAEBR E3 ubiquitin-protein ligase bre-1 ... | 92 | 0.82 | 37.7 | 27 | 43 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW. | 456 | Q4KLN8 | 487 | RNF8_RAT E3 ubiquitin-protein ligase RNF8 OS=... | 72 | 0.82 | 37.4 | 33 | 56 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; ISS:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB. | 457 | Q99MB7 | 230 | RN141_MOUSE RING finger protein 141 OS=Mus mu... | 52 | 0.82 | 36.6 | 37 | 50 | | | | | | | | | | | GO:0003677; F:DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IDA:MGI. | 458 | Q803C1 | 485 | RNF8_DANRE E3 ubiquitin-protein ligase RNF8 O... | 53 | 0.85 | 37.4 | 36 | 53 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IEA:InterPro.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; ISS:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB. | 459 | Q9Y4K3 | 522 | TRAF6_HUMAN TNF receptor-associated factor 6 ... | 46 | 0.85 | 37.4 | 41 | 57 | GO:0035631; C:CD40 receptor complex; ISS:BHF-UCL.::GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0010008; C:endosome membrane; TAS:Reactome.::GO:0009898; C:internal side of plasma membrane; ISS:BHF-UCL.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL. | | | | | | | | | | GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:UniProtKB.::GO:0043422; F:protein kinase B binding; IPI:UniProtKB.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; TAS:Reactome.::GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IMP:UniProtKB.::GO:0006916; P:anti-apoptosis; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0007254; P:JNK cascade; TAS:Reactome.::GO:0031293; P:membrane protein intracellular domain proteolysis; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.::GO:0001503; P:ossification; IEA:UniProtKB-KW.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB.::GO:0032743; P:positive regulation of interleukin-2 production; IMP:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; NAS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0045672; P:positive regulation of osteoclast differentiation; IDA:UniProtKB.::GO:0050870; P:positive regulation of T cell activation; IC:UniProtKB.::GO:0002726; P:positive regulation of T cell cytokine production; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:2000679; P:positive regulation of transcription regulatory region DNA binding; IDA:BHF-UCL.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0070555; P:response to interleukin-1; IDA:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IMP:UniProtKB.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 460 | Q2XNS1 | 231 | RN141_CANFA RING finger protein 141 OS=Canis ... | 52 | 0.85 | 36.6 | 37 | 50 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 461 | Q1MTQ0 | 692 | BRL1_SCHPO E3 ubiquitin-protein ligase brl1 O... | 61 | 0.86 | 37.4 | 28 | 43 | GO:0005721; C:centromeric heterochromatin; IDA:PomBase.::GO:0033503; C:HULC complex; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006342; P:chromatin silencing; IMP:PomBase.::GO:0006336; P:DNA replication-independent nucleosome assembly; TAS:PomBase.::GO:0071894; P:histone H2B conserved C-terminal lysine ubiquitination; IDA:PomBase.::GO:0051569; P:regulation of histone H3-K4 methylation; IMP:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEP:PomBase. | 462 | B6CJY5 | 522 | TRAF6_MACMU TNF receptor-associated factor 6 ... | 46 | 0.87 | 37.4 | 41 | 57 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro. | 463 | P25916 | 324 | BMI1_MOUSE Polycomb complex protein BMI-1 OS=... | 74 | 0.87 | 37 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016604; C:nuclear body; IDA:MGI.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0007420; P:brain development; IMP:MGI.::GO:0048704; P:embryonic skeletal system morphogenesis; IGI:MGI.::GO:0016573; P:histone acetylation; IGI:MGI.::GO:0016574; P:histone ubiquitination; IDA:MGI.::GO:0006959; P:humoral immune response; IMP:MGI.::GO:0001701; P:in utero embryonic development; IGI:MGI.::GO:0043066; P:negative regulation of apoptotic process; IGI:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0030890; P:positive regulation of B cell proliferation; IMP:HGNC.::GO:0033092; P:positive regulation of immature T cell proliferation in thymus; IMP:HGNC.::GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0021903; P:rostrocaudal neural tube patterning; IMP:MGI.::GO:0048103; P:somatic stem cell division; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 464 | B6CJY4 | 522 | TRAF6_CERAT TNF receptor-associated factor 6 ... | 46 | 0.88 | 37.4 | 41 | 57 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 465 | Q32KX7 | 326 | BMI1_BOVIN Polycomb complex protein BMI-1 OS=... | 74 | 0.88 | 37 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 466 | Q5R8L2 | 326 | BMI1_PONAB Polycomb complex protein BMI-1 OS=... | 74 | 0.91 | 37 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 467 | P35226 | 326 | BMI1_HUMAN Polycomb complex protein BMI-1 OS=... | 74 | 0.91 | 37 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0035102; C:PRC1 complex; IDA:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB. | | | | | | | | | | GO:0071535; F:RING-like zinc finger domain binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0030097; P:hemopoiesis; IEP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0048146; P:positive regulation of fibroblast proliferation; IMP:BHF-UCL.::GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0007379; P:segment specification; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 468 | Q5SDR3 | 326 | BMI1_CHICK Polycomb complex protein BMI-1 OS=... | 74 | 0.91 | 37 | 27 | 46 | GO:0031519; C:PcG protein complex; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 469 | Q8N9V2 | 468 | TRIML_HUMAN Probable E3 ubiquitin-protein lig... | 52 | 0.93 | 37.4 | 40 | 48 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 470 | Q2TBT8 | 240 | RN151_BOVIN RING finger protein 151 OS=Bos ta... | 103 | 0.93 | 36.6 | 25 | 45 | | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 471 | Q59NP8 | 631 | SPB42_CANAL ATP-dependent rRNA helicase SPB42... | 140 | 0.94 | 37.4 | 23 | 40 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006364; P:rRNA processing; IEA:UniProtKB-KW. | 472 | Q1XHT8 | 229 | TRI40_PANTR Tripartite motif-containing prote... | 48 | 0.95 | 36.6 | 38 | 54 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 473 | O54952 | 1817 | BRCA1_RAT Breast cancer type 1 susceptibility... | 54 | 0.97 | 37.4 | 37 | 57 | GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IDA:RGD. | | | | | | | | | | GO:0003684; F:damaged DNA binding; TAS:RGD.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007420; P:brain development; IEP:RGD.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0033993; P:response to lipid; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD. | 474 | Q6LFN2 | 1103 | ZNRF1_PLAF7 RING finger protein PFF0165c OS=P... | 48 | 0.98 | 37.4 | 29 | 50 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 475 | Q6BWW6 | 691 | BRE1_DEBHA E3 ubiquitin-protein ligase BRE1 O... | 204 | 0.99 | 37.4 | 22 | 43 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW. | 476 | Q59N29 | 631 | SPB41_CANAL ATP-dependent rRNA helicase SPB41... | 140 | 1 | 37.4 | 23 | 40 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006364; P:rRNA processing; IEA:UniProtKB-KW. | 477 | Q9D9R0 | 233 | RN125_MOUSE E3 ubiquitin-protein ligase RNF12... | 51 | 1 | 36.2 | 35 | 47 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; EXP:Reactome.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 478 | Q6P9F5 | 258 | TRI40_HUMAN Tripartite motif-containing prote... | 48 | 1.1 | 36.6 | 38 | 54 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 479 | Q8TEJ3 | 882 | SH3R3_HUMAN SH3 domain-containing RING finger... | 50 | 1.1 | 37.4 | 36 | 54 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 480 | Q7SZN2 | 266 | RN170_DANRE RING finger protein 170 OS=Danio ... | 110 | 1.1 | 36.6 | 25 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009790; P:embryo development; IMP:ZFIN. | 481 | Q9M9Y4 | 421 | DRIP1_ARATH E3 ubiquitin protein ligase DRIP1... | 34 | 1.1 | 37 | 44 | 62 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051865; P:protein autoubiquitination; IDA:UniProtKB. |