UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YLR017W

Length:

337

Number of sequences:

5887

Description:

YLR017W MEU1 SGDID:S000004007, Chr XII from 177608-178621, Genome Release 64-1-1, Verified ORF, "Methylthioadenosine phosphorylase (MTAP), catalyzes the initial step in the methionine salvage pathway; affects polyamine biosynthesis through regulation of ornithine decarboxylase (Spe1p) activity; regulates ADH2 gene expression"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
61	A8XGS6	285	MTAP_CAEBR S-methyl-5'-thioadenosine phosphor...	281	2e-35	135	32	50	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0017061; F:S-methyl-5-thioadenosine phosphorylase activity; IEA:EC.
									GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
62	O66839	277	PNPH_AQUAE Probable 6-oxopurine nucleoside ph...	237	8e-35	133	35	50
									GO:0004731; F:purine-nucleoside phosphorylase activity; IEA:EC.
									GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
63	Q3MHF7	283	MTAP_BOVIN S-methyl-5'-thioadenosine phosphor...	257	1e-34	133	34	52	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0017061; F:S-methyl-5-thioadenosine phosphorylase activity; IEA:EC.
									GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
64	Q8U2I1	265	PNPH_PYRFU Probable 6-oxopurine nucleoside ph...	228	4e-34	131	35	51
									GO:0004731; F:purine-nucleoside phosphorylase activity; IEA:EC.
									GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
65	B5YKP5	265	MTIP_THEYD Probable S-methyl-5'-thioinosine p...	212	3e-33	129	33	53
									GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
									GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
66	Q9KYV7	280	PNPH_STRCO Purine nucleoside phosphorylase OS...	247	3e-32	126	35	52
									GO:0004731; F:purine-nucleoside phosphorylase activity; IEA:EC.
									GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
67	Q8PB40	250	MTIP_XANCP Probable S-methyl-5'-thioinosine p...	244	1e-31	124	32	50
									GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
									GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
68	Q9PAZ2	237	MTIP_XYLFA Probable S-methyl-5'-thioinosine p...	250	2e-31	123	32	50
									GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
									GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
69	Q87ZC3	246	MTIP_PSESM Probable S-methyl-5'-thioinosine p...	226	8e-31	121	33	50
									GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
									GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
70	Q9HZK1	245	MTIP_PSEAE S-methyl-5'-thioinosine phosphoryl...	215	1e-30	121	33	50
									GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
									GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
71	Q87BR7	248	MTIP_XYLFT Probable S-methyl-5'-thioinosine p...	246	4e-30	120	31	49
									GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
									GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
72	Q2RKL6	260	PNPH_MOOTA Probable 6-oxopurine nucleoside ph...	261	7e-30	119	31	48
									GO:0004731; F:purine-nucleoside phosphorylase activity; IEA:EC.
									GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
73	O27633	280	MTIP_METTH Probable S-methyl-5'-thioinosine p...	200	2e-28	115	35	53
									GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
									GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
74	B1L719	270	PNPH_KORCO Probable 6-oxopurine nucleoside ph...	241	1e-27	114	34	51
									GO:0004731; F:purine-nucleoside phosphorylase activity; IEA:EC.
									GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
75	Q8IMU4	290	PNPH_DROME Purine nucleoside phosphorylase OS...	273	1e-26	110	29	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0004731; F:purine-nucleoside phosphorylase activity; IEA:EC.
									GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
76	Q8TZB4	256	MTIP_METKA Probable S-methyl-5'-thioinosine p...	233	3e-26	109	33	52
									GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
									GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
77	Q297F5	288	PNPH_DROPS Purine nucleoside phosphorylase OS...	264	2e-25	107	30	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0004731; F:purine-nucleoside phosphorylase activity; IEA:EC.
									GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
78	Q60367	252	MTIP_METJA Probable S-methyl-5'-thioinosine p...	234	1e-24	104	31	49
									GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
									GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
79	O28486	243	PNPH_ARCFU Probable 6-oxopurine nucleoside ph...	221	4e-17	82.8	31	46
									GO:0004731; F:purine-nucleoside phosphorylase activity; IEA:EC.
									GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
80	P23139	238	YPE2_RHORU Uncharacterized 25.8 kDa protein i...	124	8e-17	81.6	40	52
									GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.
81	Q8TQX8	258	MTIP_METAC Probable S-methyl-5'-thioinosine p...	224	0.000000000000004	77.4	29	47
									GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
									GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
82	P45563	277	XAPA_ECOLI Xanthosine phosphorylase OS=Escher...	136	0.0000001	56.2	29	43	GO:0005737; C:cytoplasm; IDA:EcoliWiki.
									GO:0004731; F:purine-nucleoside phosphorylase activity; IDA:EcoliWiki.
									GO:0015949; P:nucleobase-containing small molecule interconversion; IMP:EcoliWiki.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.
83	Q05788	311	PNPH_YEAST Purine nucleoside phosphorylase OS...	41	0.000004	51.2	54	63	GO:0005622; C:intracellular; IC:SGD.
									GO:0047724; F:inosine nucleosidase activity; IDA:SGD.::GO:0070635; F:nicotinamide riboside hydrolase activity; IDA:SGD.::GO:0004731; F:purine-nucleoside phosphorylase activity; IMP:SGD.
									GO:0046115; P:guanosine catabolic process; IMP:SGD.::GO:0006148; P:inosine catabolic process; IMP:SGD.::GO:0019358; P:nicotinate nucleotide salvage; IGI:SGD.
84	P23492	289	PNPH_MOUSE Purine nucleoside phosphorylase OS...	46	0.0003	45.4	41	61	GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:MGI.
									GO:0004731; F:purine-nucleoside phosphorylase activity; IDA:MGI.
									GO:0006161; P:deoxyguanosine catabolic process; IMP:MGI.::GO:0006149; P:deoxyinosine catabolic process; IMP:MGI.::GO:0046070; P:dGTP metabolic process; IMP:MGI.::GO:0006183; P:GTP biosynthetic process; IMP:MGI.::GO:0046115; P:guanosine catabolic process; IMP:MGI.::GO:0006148; P:inosine catabolic process; IMP:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.::GO:0046638; P:positive regulation of alpha-beta T cell differentiation; IMP:MGI.::GO:0045579; P:positive regulation of B cell differentiation; IMP:MGI.::GO:0045739; P:positive regulation of DNA repair; IMP:MGI.::GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IMP:MGI.::GO:0042102; P:positive regulation of T cell proliferation; IMP:MGI.::GO:0010332; P:response to gamma radiation; IMP:MGI.::GO:0034418; P:urate biosynthetic process; IMP:MGI.
85	Q9UTG1	315	PNPH_SCHPO Putative purine nucleoside phospho...	97	0.0003	45.4	25	47	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
									GO:0004731; F:purine-nucleoside phosphorylase activity; ISS:PomBase.
									GO:0034356; P:NAD biosynthesis via nicotinamide riboside salvage pathway; ISS:PomBase.::GO:0006152; P:purine nucleoside catabolic process; ISS:PomBase.
86	P55859	289	PNPH_BOVIN Purine nucleoside phosphorylase OS...	175	0.003	42.4	24	39	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
									GO:0004731; F:purine-nucleoside phosphorylase activity; IDA:UniProtKB.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.
87	P85973	289	PNPH_RAT Purine nucleoside phosphorylase OS=R...	46	0.003	42.4	41	57	GO:0005737; C:cytoplasm; IDA:RGD.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.
									GO:0004731; F:purine-nucleoside phosphorylase activity; IDA:RGD.
									GO:0042278; P:purine nucleoside metabolic process; IDA:RGD.::GO:0043101; P:purine-containing compound salvage; TAS:RGD.
88	P77834	274	PUNA_GEOSE Purine nucleoside phosphorylase 1 ...	165	0.01	40.8	25	43
									GO:0004731; F:purine-nucleoside phosphorylase activity; IEA:EC.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.
89	P00491	289	PNPH_HUMAN Purine nucleoside phosphorylase OS...	46	0.024	39.7	37	57	GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.
									GO:0008144; F:drug binding; IDA:UniProtKB.::GO:0001882; F:nucleoside binding; IDA:UniProtKB.::GO:0042301; F:phosphate ion binding; IDA:UniProtKB.::GO:0002060; F:purine base binding; IDA:UniProtKB.::GO:0004731; F:purine-nucleoside phosphorylase activity; IDA:UniProtKB.
									GO:0006955; P:immune response; IMP:UniProtKB.::GO:0006148; P:inosine catabolic process; IDA:MGI.::GO:0070970; P:interleukin-2 secretion; IMP:UniProtKB.::GO:0034356; P:NAD biosynthesis via nicotinamide riboside salvage pathway; IGI:UniProtKB.::GO:0006738; P:nicotinamide riboside catabolic process; IDA:UniProtKB.::GO:0046638; P:positive regulation of alpha-beta T cell differentiation; IDA:MGI.::GO:0042102; P:positive regulation of T cell proliferation; IDA:MGI.::GO:0006144; P:purine base metabolic process; TAS:Reactome.::GO:0006195; P:purine nucleotide catabolic process; TAS:Reactome.::GO:0043101; P:purine-containing compound salvage; TAS:Reactome.::GO:0042493; P:response to drug; IDA:UniProtKB.::GO:0034418; P:urate biosynthetic process; IDA:MGI.
90	P46862	268	PUNA_MYCLE Purine nucleoside phosphorylase OS...	80	0.34	35.8	28	43
									GO:0004731; F:purine-nucleoside phosphorylase activity; IEA:EC.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.
91	P81989	282	PUNA_CELSP Purine nucleoside phosphorylase OS...	50	0.46	35.4	34	50
									GO:0004731; F:purine-nucleoside phosphorylase activity; IEA:EC.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.

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