Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLR006C
Length:
712
Number of sequences:
5887
Description:
YLR006C SSK1 SGDID:S000003996, Chr XII from 163893-161755, Genome Release 64-1-1, reverse complement, Verified ORF, "Cytoplasmic response regulator; part of a two-component signal transducer that mediates osmosensing via a phosphorelay mechanism; required for mitophagy; dephosphorylated form is degraded by the ubiquitin-proteasome system; potential Cdc28p substrate"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q07084    712   SSK1_YEAST Osomolarity two-component system p...7120     1466     100     100GO:0005737; C:cytoplasm; IDA:SGD.
GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:SGD.::GO:0042803; F:protein homodimerization activity; IDA:SGD.::GO:0030295; F:protein kinase activator activity; IMP:SGD.::GO:0000156; F:two-component response regulator activity; IMP:SGD.
GO:0000167; P:activation of MAPKKK activity involved in osmosensory signaling pathway; IMP:SGD.::GO:0007234; P:osmosensory signaling pathway via two-component system; IDA:SGD.::GO:0031954; P:positive regulation of protein autophosphorylation; IDA:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
2P87323    522   MCS4_SCHPO Response regulator mcs4 OS=Schizos...1731e-50     189     53     69GO:0032153; C:cell division site; IDA:PomBase.::GO:0005737; C:cytoplasm; IDA:PomBase.
GO:0000156; F:two-component response regulator activity; IEA:InterPro.
GO:0070301; P:cellular response to hydrogen peroxide; IMP:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0046685; P:response to arsenic-containing substance; IMP:PomBase.::GO:0031098; P:stress-activated protein kinase signaling cascade; IGI:PomBase.
3Q54YH4    1969   DHKB_DICDI Hybrid signal transduction histidi...1408e-18     92.4     40     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
4Q86CZ2    1213   DHKK_DICDI Hybrid signal transduction histidi...1490.00000000000001     81.6     34     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0019933; P:cAMP-mediated signaling; IMP:dictyBase.::GO:0031154; P:culmination involved in sorocarp development; IMP:dictyBase.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
5Q86AT9    1736   DHKI_DICDI Hybrid signal transduction histidi...1480.00000000000004     80.1     32     49GO:0016020; C:membrane; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0006928; P:cellular component movement; IGI:dictyBase.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
6Q54SK5    2388   DHKM_DICDI Hybrid signal transduction histidi...1360.0000000000002     78.2     33     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0048102; P:autophagic cell death; IMP:dictyBase.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
7Q54Q69    3432   DHKG_DICDI Hybrid signal transduction histidi...1470.0000000000007     76.3     35     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
8Q54U87    2150   DHKA_DICDI Hybrid signal transduction histidi...1420.000000000008     72.8     32     49GO:0009897; C:external side of plasma membrane; TAS:dictyBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; ISS:GOC.
GO:0005524; F:ATP binding; TAS:dictyBase.::GO:0009784; F:transmembrane receptor histidine kinase activity; IGI:dictyBase.::GO:0000156; F:two-component response regulator activity; ISS:dictyBase.::GO:0000155; F:two-component sensor activity; ISS:dictyBase.
GO:0019933; P:cAMP-mediated signaling; IMP:dictyBase.::GO:0009736; P:cytokinin mediated signaling pathway; IEA:UniProtKB-KW.::GO:0051344; P:negative regulation of cyclic-nucleotide phosphodiesterase activity; TAS:dictyBase.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0031150; P:sorocarp stalk development; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:dictyBase.
9Q55E44    1699   DHKE_DICDI Hybrid signal transduction histidi...1440.00000000003     71.2     33     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
10Q54YZ9    2062   DHKJ_DICDI Hybrid signal transduction histidi...1610.0000000002     68.2     32     46GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0016021; C:integral to membrane; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
11Q9P7Q7    1639   MAK1_SCHPO Peroxide stress-activated histidin...1440.0000000009     66.2     30     47GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0016020; C:membrane; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.::GO:0000155; F:two-component sensor activity; NAS:PomBase.
GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0031137; P:regulation of conjugation with cellular fusion; IMP:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; TAS:PomBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0031098; P:stress-activated protein kinase signaling cascade; IGI:PomBase.
12Q3S4A7    922   AHK5_ARATH Histidine kinase 5 OS=Arabidopsis ...1550.000000001     65.5     28     52GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0005773; C:vacuole; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.::GO:0070301; P:cellular response to hydrogen peroxide; IMP:UniProtKB.::GO:0071219; P:cellular response to molecule of bacterial origin; IMP:UniProtKB.::GO:0071732; P:cellular response to nitric oxide; IMP:UniProtKB.::GO:0009736; P:cytokinin mediated signaling pathway; TAS:TAIR.::GO:0006952; P:defense response; IEA:UniProtKB-KW.::GO:0009873; P:ethylene mediated signaling pathway; IEA:UniProtKB-KW.::GO:0009788; P:negative regulation of abscisic acid mediated signaling pathway; IMP:UniProtKB.::GO:0010105; P:negative regulation of ethylene mediated signaling pathway; IMP:UniProtKB.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0090333; P:regulation of stomatal closure; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0048364; P:root development; IMP:UniProtKB.
13O34903    228   YKOG_BACSU Uncharacterized transcriptional re...1410.000000003     61.2     33     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
14Q7MD16    857   LUXQ_VIBVY Autoinducer 2 sensor kinase/phosph...1520.000000004     63.9     31     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
15Q8D5Z6    857   LUXQ_VIBVU Autoinducer 2 sensor kinase/phosph...1520.000000004     63.9     31     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
16Q9P896    682   TCSA_EMENI Two-component system protein A OS=...1640.000000005     63.5     27     47GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0016020; C:membrane; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000156; F:two-component response regulator activity; NAS:UniProtKB.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0030437; P:ascospore formation; IMP:UniProtKB.::GO:0048315; P:conidium formation; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
17Q87GU5    858   LUXQ_VIBPA Autoinducer 2 sensor kinase/phosph...1520.000000005     63.5     34     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
18P48027    907   GACS_PSESY Sensor protein gacS OS=Pseudomonas...1420.000000006     63.2     29     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
19Q9C5U1    1036   AHK3_ARATH Histidine kinase 3 OS=Arabidopsis ...1420.000000007     63.2     27     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0009884; F:cytokinin receptor activity; TAS:TAIR.::GO:0005034; F:osmosensor activity; IGI:TAIR.::GO:0043424; F:protein histidine kinase binding; IPI:UniProtKB.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0071215; P:cellular response to abscisic acid stimulus; IMP:UniProtKB.::GO:0070417; P:cellular response to cold; IMP:UniProtKB.::GO:0016036; P:cellular response to phosphate starvation; IMP:UniProtKB.::GO:0071329; P:cellular response to sucrose stimulus; IMP:UniProtKB.::GO:0042742; P:defense response to bacterium; IDA:TAIR.::GO:0010150; P:leaf senescence; IMP:TAIR.::GO:0034757; P:negative regulation of iron ion transport; IMP:UniProtKB.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0010087; P:phloem or xylem histogenesis; IMP:UniProtKB.::GO:0010271; P:regulation of chlorophyll catabolic process; IMP:TAIR.::GO:0009909; P:regulation of flower development; IMP:UniProtKB.::GO:0048509; P:regulation of meristem development; IMP:UniProtKB.::GO:0010029; P:regulation of seed germination; IMP:TAIR.::GO:0048831; P:regulation of shoot development; IMP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0009651; P:response to salt stress; IEP:TAIR.::GO:0009414; P:response to water deprivation; IEP:TAIR.::GO:0080117; P:secondary growth; IMP:UniProtKB.
20A7N6S2    681   CQSS_VIBHB CAI-1 autoinducer sensor kinase/ph...1730.00000003     60.5     27     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
21Q9C5U2    1176   AHK2_ARATH Histidine kinase 2 OS=Arabidopsis ...1290.00000005     60.1     28     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0009884; F:cytokinin receptor activity; TAS:TAIR.::GO:0042802; F:identical protein binding; IPI:UniProtKB.::GO:0005034; F:osmosensor activity; IGI:TAIR.::GO:0043424; F:protein histidine kinase binding; IPI:UniProtKB.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0071215; P:cellular response to abscisic acid stimulus; IMP:UniProtKB.::GO:0070417; P:cellular response to cold; IMP:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0034757; P:negative regulation of iron ion transport; IMP:UniProtKB.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0010087; P:phloem or xylem histogenesis; IMP:UniProtKB.::GO:0010271; P:regulation of chlorophyll catabolic process; IMP:TAIR.::GO:0009909; P:regulation of flower development; IMP:UniProtKB.::GO:0048509; P:regulation of meristem development; IMP:UniProtKB.::GO:0010029; P:regulation of seed germination; IMP:TAIR.::GO:0048831; P:regulation of shoot development; IMP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0009651; P:response to salt stress; IEP:TAIR.::GO:0009636; P:response to toxin; IMP:UniProtKB.::GO:0009414; P:response to water deprivation; IEP:TAIR.::GO:0080117; P:secondary growth; IMP:UniProtKB.
22A6X580    123   DIVK_OCHA4 Polar-differentiation response reg...1350.0000001     55.5     29     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
23Q8FW53    123   DIVK_BRUSU Polar-differentiation response reg...1320.0000002     55.1     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
24A9WYT1    123   DIVK_BRUSI Polar-differentiation response reg...1320.0000002     55.1     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
25A5VUU3    123   DIVK_BRUO2 Polar-differentiation response reg...1320.0000002     55.1     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
26Q8YC73    123   DIVK_BRUME Polar-differentiation response reg...1320.0000002     55.1     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
27A9MBQ2    123   DIVK_BRUC2 Polar-differentiation response reg...1320.0000002     55.1     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
28Q7BBW0    123   DIVK_BRUAB Polar-differentiation response reg...1320.0000002     55.1     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
29Q2YKN1    123   DIVK_BRUA2 Polar-differentiation response reg...1320.0000002     55.1     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
30B2SB45    123   DIVK_BRUA1 Polar-differentiation response reg...1320.0000002     55.1     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
31P54302    859   LUXQ_VIBHA Autoinducer 2 sensor kinase/phosph...1590.0000003     57.4     30     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
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