rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | P66875 | 388 | METB_MYCTU Cystathionine gamma-synthase OS=My... | 256 | 0.00001 | 51.6 | 25 | 42 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:MTBBASE. | | | | | | | | | | GO:0004123; F:cystathionine gamma-lyase activity; IDA:MTBBASE.::GO:0003962; F:cystathionine gamma-synthase activity; IDA:MTBBASE.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0019343; P:cysteine biosynthetic process via cystathionine; IMP:MTBBASE.::GO:0019279; P:L-methionine biosynthetic process from L-homoserine via cystathionine; IMP:MTBBASE. | 32 | P66876 | 388 | METB_MYCBO Cystathionine gamma-synthase OS=My... | 256 | 0.00001 | 51.6 | 25 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 33 | P53780 | 464 | METC_ARATH Cystathionine beta-lyase, chloropl... | 251 | 0.00001 | 51.6 | 25 | 45 | GO:0009570; C:chloroplast stroma; IDA:TAIR. | | | | | | | | | | GO:0004121; F:cystathionine beta-lyase activity; IMP:TAIR.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0019279; P:L-methionine biosynthetic process from L-homoserine via cystathionine; TAS:TAIR. | 34 | P95199 | 406 | METZ_MYCTU O-succinylhomoserine sulfhydrylase... | 353 | 0.00001 | 51.6 | 23 | 40 | | | | | | | | | | | GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0071268; P:homocysteine biosynthetic process; IEA:InterPro.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 35 | P24601 | 319 | METB_HERAU Probable cystathionine gamma-synth... | 233 | 0.00001 | 50.8 | 23 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 36 | P32929 | 405 | CGL_HUMAN Cystathionine gamma-lyase OS=Homo s... | 288 | 0.00002 | 50.8 | 27 | 43 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004123; F:cystathionine gamma-lyase activity; IDA:UniProtKB.::GO:0047982; F:homocysteine desulfhydrase activity; TAS:Reactome.::GO:0080146; F:L-cysteine desulfhydrase activity; TAS:Reactome.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IMP:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IDA:UniProtKB. | | | | | | | | | | GO:0019344; P:cysteine biosynthetic process; IDA:UniProtKB.::GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:UniProtKB.::GO:0070814; P:hydrogen sulfide biosynthetic process; IDA:UniProtKB.::GO:0051289; P:protein homotetramerization; IPI:UniProtKB.::GO:0044524; P:protein sulfhydration; IMP:UniProtKB.::GO:0018272; P:protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; IDA:UniProtKB.::GO:0000098; P:sulfur amino acid catabolic process; TAS:Reactome.::GO:0019346; P:transsulfuration; TAS:Reactome. | 37 | P06106 | 444 | MET17_YEAST Protein MET17 OS=Saccharomyces ce... | 111 | 0.00004 | 49.7 | 30 | 53 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD. | | | | | | | | | | GO:0004124; F:cysteine synthase activity; IDA:SGD.::GO:0003961; F:O-acetylhomoserine aminocarboxypropyltransferase activity; IDA:SGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | | 38 | O13326 | 429 | CYSD_SCHPO O-acetylhomoserine (thiol)-lyase O... | 191 | 0.0001 | 48.5 | 25 | 46 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0004124; F:cysteine synthase activity; ISS:PomBase.::GO:0003961; F:O-acetylhomoserine aminocarboxypropyltransferase activity; TAS:PomBase.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | | 39 | P53101 | 465 | STR3_YEAST Cystathionine beta-lyase OS=Saccha... | 374 | 0.0001 | 48.5 | 24 | 40 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005777; C:peroxisome; IDA:SGD. | | | | | | | | | | GO:0004121; F:cystathionine beta-lyase activity; IMP:SGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0071266; P:'de novo' L-methionine biosynthetic process; IEA:InterPro.::GO:0019346; P:transsulfuration; IMP:SGD. | 40 | P50125 | 437 | CYSD_EMENI O-acetylhomoserine (thiol)-lyase O... | 111 | 0.001 | 45.4 | 28 | 46 | | | | | | | | | | | GO:0003961; F:O-acetylhomoserine aminocarboxypropyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW. | 41 | Q59829 | 392 | CYSA_STRCO Putative cystathionine gamma-lyase... | 256 | 0.002 | 44.7 | 24 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004123; F:cystathionine gamma-lyase activity; IEA:EC.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW. | 42 | Q92441 | 444 | MET17_KLULA Protein MET17 OS=1267 / NRRL Y-11... | 64 | 0.005 | 43.1 | 36 | 64 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0003961; F:O-acetylhomoserine aminocarboxypropyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | | 43 | P44502 | 369 | METB_HAEIN Cystathionine gamma-synthase OS=Ha... | 73 | 0.01 | 42 | 33 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 44 | B3WDL0 | 410 | GLYA_LACCB Serine hydroxymethyltransferase OS... | 52 | 0.025 | 40.8 | 37 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 45 | Q03A26 | 410 | GLYA_LACC3 Serine hydroxymethyltransferase OS... | 52 | 0.025 | 40.8 | 37 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 46 | Q07703 | 396 | METC_BORAV Cystathionine beta-lyase OS=Bordet... | 257 | 0.042 | 40 | 24 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 47 | Q2ST43 | 413 | GLYA_MYCCT Serine hydroxymethyltransferase OS... | 131 | 0.071 | 39.7 | 25 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 48 | Q8R887 | 413 | GLYA_THETN Serine hydroxymethyltransferase OS... | 62 | 0.12 | 38.9 | 32 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 49 | Q6MS85 | 413 | GLYA_MYCMS Serine hydroxymethyltransferase OS... | 176 | 0.13 | 38.5 | 23 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 50 | Q88UT5 | 412 | GLYA_LACPL Serine hydroxymethyltransferase OS... | 52 | 0.15 | 38.5 | 37 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 51 | B1I6M4 | 415 | GLYA_DESAP Serine hydroxymethyltransferase OS... | 66 | 0.15 | 38.5 | 30 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 52 | Q65DW5 | 415 | GLYA_BACLD Serine hydroxymethyltransferase OS... | 57 | 0.24 | 37.7 | 33 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 53 | B0K631 | 413 | GLYA_THEPX Serine hydroxymethyltransferase OS... | 62 | 0.25 | 37.7 | 31 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 54 | B0K742 | 413 | GLYA_THEP3 Serine hydroxymethyltransferase OS... | 62 | 0.25 | 37.7 | 31 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 55 | Q89AK4 | 429 | BIOA_BUCBP Adenosylmethionine-8-amino-7-oxono... | 73 | 0.28 | 37.7 | 29 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004015; F:adenosylmethionine-8-amino-7-oxononanoate transaminase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW. | 56 | Q3A934 | 421 | GLYA_CARHZ Serine hydroxymethyltransferase OS... | 52 | 0.33 | 37.4 | 33 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 57 | O13426 | 470 | GLYC_CANAL Serine hydroxymethyltransferase, c... | 71 | 0.55 | 36.6 | 35 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:CGD. | | | | | | | | | | GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 58 | O94350 | 390 | CBL_SCHPO Cystathionine beta-lyase OS=Schizos... | 279 | 0.55 | 36.6 | 24 | 44 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005777; C:peroxisome; ISS:PomBase. | | | | | | | | | | GO:0004121; F:cystathionine beta-lyase activity; ISS:PomBase.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0019279; P:L-methionine biosynthetic process from L-homoserine via cystathionine; IC:PomBase. | 59 | Q5WB66 | 417 | GLYA_BACSK Serine hydroxymethyltransferase OS... | 68 | 0.58 | 36.6 | 29 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 60 | Q2RTB8 | 430 | GLYA2_RHORT Serine hydroxymethyltransferase 2... | 98 | 0.6 | 36.6 | 31 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 61 | P43623 | 340 | METC_YEAST Putative cystathionine beta-lyase ... | 296 | 0.62 | 36.2 | 22 | 39 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0047804; F:cysteine-S-conjugate beta-lyase activity; IDA:SGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0019450; P:L-cysteine catabolic process to pyruvate; IMP:SGD.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. |