Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLL058W
Length:
575
Number of sequences:
5887
Description:
YLL058W YLL058W SGDID:S000003981, Chr XII from 23569-25296, Genome Release 64-1-1, Uncharacterized ORF, "Putative protein of unknown function with similarity to Str2p, which is a cystathionine gamma-synthase important in sulfur metabolism; YLL058W is not an essential gene"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P66875    388   METB_MYCTU Cystathionine gamma-synthase OS=My...2560.00001     51.6     25     42GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:MTBBASE.
GO:0004123; F:cystathionine gamma-lyase activity; IDA:MTBBASE.::GO:0003962; F:cystathionine gamma-synthase activity; IDA:MTBBASE.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0019343; P:cysteine biosynthetic process via cystathionine; IMP:MTBBASE.::GO:0019279; P:L-methionine biosynthetic process from L-homoserine via cystathionine; IMP:MTBBASE.
32P66876    388   METB_MYCBO Cystathionine gamma-synthase OS=My...2560.00001     51.6     25     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
33P53780    464   METC_ARATH Cystathionine beta-lyase, chloropl...2510.00001     51.6     25     45GO:0009570; C:chloroplast stroma; IDA:TAIR.
GO:0004121; F:cystathionine beta-lyase activity; IMP:TAIR.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0019279; P:L-methionine biosynthetic process from L-homoserine via cystathionine; TAS:TAIR.
34P95199    406   METZ_MYCTU O-succinylhomoserine sulfhydrylase...3530.00001     51.6     23     40
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0071268; P:homocysteine biosynthetic process; IEA:InterPro.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
35P24601    319   METB_HERAU Probable cystathionine gamma-synth...2330.00001     50.8     23     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
36P32929    405   CGL_HUMAN Cystathionine gamma-lyase OS=Homo s...2880.00002     50.8     27     43GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004123; F:cystathionine gamma-lyase activity; IDA:UniProtKB.::GO:0047982; F:homocysteine desulfhydrase activity; TAS:Reactome.::GO:0080146; F:L-cysteine desulfhydrase activity; TAS:Reactome.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IMP:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IDA:UniProtKB.
GO:0019344; P:cysteine biosynthetic process; IDA:UniProtKB.::GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:UniProtKB.::GO:0070814; P:hydrogen sulfide biosynthetic process; IDA:UniProtKB.::GO:0051289; P:protein homotetramerization; IPI:UniProtKB.::GO:0044524; P:protein sulfhydration; IMP:UniProtKB.::GO:0018272; P:protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; IDA:UniProtKB.::GO:0000098; P:sulfur amino acid catabolic process; TAS:Reactome.::GO:0019346; P:transsulfuration; TAS:Reactome.
37P06106    444   MET17_YEAST Protein MET17 OS=Saccharomyces ce...1110.00004     49.7     30     53GO:0005737; C:cytoplasm; IDA:SGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD.
GO:0004124; F:cysteine synthase activity; IDA:SGD.::GO:0003961; F:O-acetylhomoserine aminocarboxypropyltransferase activity; IDA:SGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
38O13326    429   CYSD_SCHPO O-acetylhomoserine (thiol)-lyase O...1910.0001     48.5     25     46GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0004124; F:cysteine synthase activity; ISS:PomBase.::GO:0003961; F:O-acetylhomoserine aminocarboxypropyltransferase activity; TAS:PomBase.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
39P53101    465   STR3_YEAST Cystathionine beta-lyase OS=Saccha...3740.0001     48.5     24     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005777; C:peroxisome; IDA:SGD.
GO:0004121; F:cystathionine beta-lyase activity; IMP:SGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0071266; P:'de novo' L-methionine biosynthetic process; IEA:InterPro.::GO:0019346; P:transsulfuration; IMP:SGD.
40P50125    437   CYSD_EMENI O-acetylhomoserine (thiol)-lyase O...1110.001     45.4     28     46
GO:0003961; F:O-acetylhomoserine aminocarboxypropyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW.
41Q59829    392   CYSA_STRCO Putative cystathionine gamma-lyase...2560.002     44.7     24     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004123; F:cystathionine gamma-lyase activity; IEA:EC.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW.
42Q92441    444   MET17_KLULA Protein MET17 OS=1267 / NRRL Y-11...640.005     43.1     36     64GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0003961; F:O-acetylhomoserine aminocarboxypropyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
43P44502    369   METB_HAEIN Cystathionine gamma-synthase OS=Ha...730.01     42     33     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
44B3WDL0    410   GLYA_LACCB Serine hydroxymethyltransferase OS...520.025     40.8     37     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
45Q03A26    410   GLYA_LACC3 Serine hydroxymethyltransferase OS...520.025     40.8     37     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
46Q07703    396   METC_BORAV Cystathionine beta-lyase OS=Bordet...2570.042     40     24     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
47Q2ST43    413   GLYA_MYCCT Serine hydroxymethyltransferase OS...1310.071     39.7     25     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
48Q8R887    413   GLYA_THETN Serine hydroxymethyltransferase OS...620.12     38.9     32     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
49Q6MS85    413   GLYA_MYCMS Serine hydroxymethyltransferase OS...1760.13     38.5     23     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
50Q88UT5    412   GLYA_LACPL Serine hydroxymethyltransferase OS...520.15     38.5     37     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
51B1I6M4    415   GLYA_DESAP Serine hydroxymethyltransferase OS...660.15     38.5     30     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
52Q65DW5    415   GLYA_BACLD Serine hydroxymethyltransferase OS...570.24     37.7     33     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
53B0K631    413   GLYA_THEPX Serine hydroxymethyltransferase OS...620.25     37.7     31     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
54B0K742    413   GLYA_THEP3 Serine hydroxymethyltransferase OS...620.25     37.7     31     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
55Q89AK4    429   BIOA_BUCBP Adenosylmethionine-8-amino-7-oxono...730.28     37.7     29     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004015; F:adenosylmethionine-8-amino-7-oxononanoate transaminase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
56Q3A934    421   GLYA_CARHZ Serine hydroxymethyltransferase OS...520.33     37.4     33     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
57O13426    470   GLYC_CANAL Serine hydroxymethyltransferase, c...710.55     36.6     35     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:CGD.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
58O94350    390   CBL_SCHPO Cystathionine beta-lyase OS=Schizos...2790.55     36.6     24     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005777; C:peroxisome; ISS:PomBase.
GO:0004121; F:cystathionine beta-lyase activity; ISS:PomBase.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0019279; P:L-methionine biosynthetic process from L-homoserine via cystathionine; IC:PomBase.
59Q5WB66    417   GLYA_BACSK Serine hydroxymethyltransferase OS...680.58     36.6     29     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
60Q2RTB8    430   GLYA2_RHORT Serine hydroxymethyltransferase 2...980.6     36.6     31     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
61P43623    340   METC_YEAST Putative cystathionine beta-lyase ...2960.62     36.2     22     39GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0047804; F:cysteine-S-conjugate beta-lyase activity; IDA:SGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0019450; P:L-cysteine catabolic process to pyruvate; IMP:SGD.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
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