| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | C8Z891 | 576 | AIM14_YEAS8 Probable metalloreductase AIM14 O... | 244 | 0.0001 | 49.3 | 27 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW. | 32 | Q9ES45 | 1517 | DUOX2_RAT Dual oxidase 2 OS=Rattus norvegicus... | 430 | 0.0001 | 49.3 | 22 | 41 | GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016174; F:NAD(P)H oxidase activity; IEA:EC.::GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042335; P:cuticle development; ISS:UniProtKB.::GO:0019221; P:cytokine-mediated signaling pathway; ISS:UniProtKB.::GO:0042446; P:hormone biosynthetic process; IEA:UniProtKB-KW.::GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW.::GO:0051591; P:response to cAMP; ISS:UniProtKB.::GO:0006590; P:thyroid hormone generation; TAS:RGD. | 33 | A6ZU25 | 570 | AIM14_YEAS7 Probable metalloreductase AIM14 O... | 244 | 0.0001 | 48.9 | 27 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW. | 34 | B3LHL3 | 570 | AIM14_YEAS1 Probable metalloreductase AIM14 O... | 244 | 0.0001 | 48.9 | 27 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW. | 35 | Q12209 | 686 | FRE8_YEAST Probable ferric reductase transmem... | 151 | 0.0001 | 48.9 | 22 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0000293; F:ferric-chelate reductase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro. | | | | | | | | | | GO:0006875; P:cellular metal ion homeostasis; IMP:SGD.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW. | 36 | C7GPP6 | 570 | AIM14_YEAS2 Probable metalloreductase AIM14 O... | 244 | 0.0001 | 48.9 | 27 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW. | 37 | B9WB34 | 537 | AIM14_CANDC Probable metalloreductase AIM14 O... | 362 | 0.0004 | 47.4 | 24 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW. | 38 | O46522 | 570 | CY24B_BOVIN Cytochrome b-245 heavy chain OS=B... | 386 | 0.0005 | 47 | 22 | 40 | | | | | | | | | | | GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0022900; P:electron transport chain; IEA:UniProtKB-KW. | 39 | Q95L74 | 570 | CY24B_BISBI Cytochrome b-245 heavy chain OS=B... | 386 | 0.0005 | 47 | 22 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0022900; P:electron transport chain; IEA:UniProtKB-KW. | 40 | Q86GL4 | 698 | NOXB_DICDI Superoxide-generating NADPH oxidas... | 346 | 0.0006 | 47 | 21 | 40 | GO:0043020; C:NADPH oxidase complex; ISS:dictyBase. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; ISS:dictyBase.::GO:0020037; F:heme binding; ISS:dictyBase.::GO:0050661; F:NADP binding; ISS:dictyBase.::GO:0016175; F:superoxide-generating NADPH oxidase activity; IMP:dictyBase. | | | | | | | | | | GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0030587; P:sorocarp development; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:dictyBase.::GO:0042554; P:superoxide anion generation; IMP:dictyBase.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 41 | Q75CQ8 | 686 | FRE8_ASHGO Probable ferric reductase transmem... | 110 | 0.0006 | 47 | 29 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0000293; F:ferric-chelate reductase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro. | | | | | | | | | | GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW. | 42 | A5DE11 | 482 | AIM14_PICGU Probable metalloreductase AIM14 O... | 433 | 0.001 | 45.4 | 24 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW. | 43 | Q61093 | 570 | CY24B_MOUSE Cytochrome b-245 heavy chain OS=M... | 389 | 0.002 | 45.1 | 22 | 41 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0050665; P:hydrogen peroxide biosynthetic process; IMP:MGI. | 44 | A7TQE6 | 519 | AIM14_VANPO Probable metalloreductase AIM14 O... | 479 | 0.003 | 44.3 | 23 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW. | 45 | P04839 | 570 | CY24B_HUMAN Cytochrome b-245 heavy chain OS=H... | 384 | 0.003 | 44.3 | 21 | 38 | GO:0043020; C:NADPH oxidase complex; IDA:BHF-UCL.::GO:0030670; C:phagocytic vesicle membrane; TAS:Reactome. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IMP:BHF-UCL.::GO:0020037; F:heme binding; IMP:BHF-UCL.::GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.::GO:0016175; F:superoxide-generating NADPH oxidase activity; TAS:BHF-UCL.::GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006954; P:inflammatory response; TAS:ProtInc.::GO:0045087; P:innate immune response; IMP:BHF-UCL.::GO:0045730; P:respiratory burst; IMP:BHF-UCL.::GO:0042554; P:superoxide anion generation; IDA:BHF-UCL. | 46 | Q9NRD8 | 1548 | DUOX2_HUMAN Dual oxidase 2 OS=Homo sapiens (H... | 431 | 0.004 | 44.3 | 23 | 41 | GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005509; F:calcium ion binding; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016174; F:NAD(P)H oxidase activity; IDA:UniProtKB.::GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042335; P:cuticle development; ISS:UniProtKB.::GO:0019221; P:cytokine-mediated signaling pathway; IDA:UniProtKB.::GO:0042446; P:hormone biosynthetic process; IEA:UniProtKB-KW.::GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW.::GO:0051591; P:response to cAMP; IDA:UniProtKB.::GO:0009615; P:response to virus; IDA:UniProtKB. | 47 | Q9HBY0 | 568 | NOX3_HUMAN NADPH oxidase 3 OS=Homo sapiens (H... | 384 | 0.004 | 43.9 | 21 | 38 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro. | | | | | | | | | | | 48 | Q8CIZ9 | 591 | NOX1_MOUSE NADPH oxidase 1 OS=Mus musculus (M... | 311 | 0.005 | 43.9 | 23 | 41 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005768; C:endosome; IMP:MGI.::GO:0071438; C:invadopodium membrane; ISS:UniProtKB. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0016175; F:superoxide-generating NADPH oxidase activity; IDA:MGI. | | | | | | | | | | GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0030198; P:extracellular matrix organization; IMP:MGI.::GO:0072592; P:oxygen metabolic process; IMP:MGI.::GO:0003081; P:regulation of systemic arterial blood pressure by renin-angiotensin; IMP:MGI.::GO:0042554; P:superoxide anion generation; IDA:MGI. | 49 | O81210 | 905 | RBOHC_ARATH Respiratory burst oxidase homolog... | 474 | 0.009 | 43.1 | 19 | 38 | GO:0005887; C:integral to plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016174; F:NAD(P)H oxidase activity; IMP:TAIR.::GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009060; P:aerobic respiration; IMP:TAIR.::GO:0033198; P:response to ATP; IMP:TAIR.::GO:0010053; P:root epidermal cell differentiation; IMP:TAIR. | 50 | Q9WV87 | 563 | NOX1_RAT NADPH oxidase 1 OS=Rattus norvegicus... | 248 | 0.019 | 42 | 21 | 40 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0071438; C:invadopodium membrane; IEA:UniProtKB-SubCell.::GO:0043020; C:NADPH oxidase complex; IDA:RGD. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:RGD.::GO:0016175; F:superoxide-generating NADPH oxidase activity; IDA:RGD. | | | | | | | | | | GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IMP:RGD.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:BHF-UCL.::GO:0000302; P:response to reactive oxygen species; IDA:RGD.::GO:0007165; P:signal transduction; IDA:RGD.::GO:0042554; P:superoxide anion generation; IMP:BHF-UCL.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 51 | Q9SW17 | 849 | RBOHG_ARATH Putative respiratory burst oxidas... | 467 | 0.023 | 42 | 21 | 35 | GO:0022626; C:cytosolic ribosome; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005773; C:vacuole; IDA:TAIR. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0050664; F:oxidoreductase activity, acting on NADH or NADPH, oxygen as acceptor; IEA:InterPro.::GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 52 | Q754F4 | 516 | AIM14_ASHGO Probable metalloreductase AIM14 O... | 437 | 0.042 | 40.8 | 21 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW. | 53 | Q924V1 | 578 | NOX4_RAT NADPH oxidase 4 OS=Rattus norvegicus... | 298 | 0.24 | 38.5 | 21 | 38 | GO:0016324; C:apical plasma membrane; IDA:RGD.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0043020; C:NADPH oxidase complex; IDA:RGD. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016174; F:NAD(P)H oxidase activity; IDA:RGD.::GO:0005515; F:protein binding; IPI:RGD. | | | | | | | | | | GO:0007569; P:cell aging; ISS:UniProtKB.::GO:0000902; P:cell morphogenesis; ISS:UniProtKB.::GO:0071320; P:cellular response to cAMP; IEP:RGD.::GO:0071480; P:cellular response to gamma radiation; IEP:RGD.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEP:RGD.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:RGD.::GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IMP:RGD.::GO:0014911; P:positive regulation of smooth muscle cell migration; IMP:RGD.::GO:0051496; P:positive regulation of stress fiber assembly; IMP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0042554; P:superoxide anion generation; ISS:UniProtKB. | 54 | Q9Y5S8 | 564 | NOX1_HUMAN NADPH oxidase 1 OS=Homo sapiens (H... | 315 | 0.27 | 38.1 | 20 | 41 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005769; C:early endosome; IDA:BHF-UCL.::GO:0071438; C:invadopodium membrane; IDA:UniProtKB.::GO:0043020; C:NADPH oxidase complex; IDA:BHF-UCL. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0050661; F:NADP binding; IC:BHF-UCL.::GO:0048365; F:Rac GTPase binding; IPI:BHF-UCL.::GO:0016175; F:superoxide-generating NADPH oxidase activity; TAS:UniProtKB.::GO:0030171; F:voltage-gated proton channel activity; IDA:BHF-UCL. | | | | | | | | | | GO:0001525; P:angiogenesis; IMP:BHF-UCL.::GO:0016477; P:cell migration; IMP:BHF-UCL.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006746; P:FADH2 metabolic process; NAS:UniProtKB.::GO:0042743; P:hydrogen peroxide metabolic process; IDA:BHF-UCL.::GO:0006954; P:inflammatory response; TAS:BHF-UCL.::GO:0051454; P:intracellular pH elevation; IDA:BHF-UCL.::GO:0006739; P:NADP metabolic process; IC:BHF-UCL.::GO:0045726; P:positive regulation of integrin biosynthetic process; IMP:BHF-UCL.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; ISS:BHF-UCL.::GO:0010575; P:positive regulation vascular endothelial growth factor production; IEP:BHF-UCL.::GO:0045730; P:respiratory burst; TAS:BHF-UCL.::GO:0009268; P:response to pH; IDA:BHF-UCL.::GO:0007165; P:signal transduction; TAS:BHF-UCL.::GO:0042554; P:superoxide anion generation; IDA:BHF-UCL. | 55 | C5E4F2 | 526 | AIM14_ZYGRC Probable metalloreductase AIM14 O... | 193 | 0.31 | 38.1 | 22 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW. | 56 | Q9JHI8 | 578 | NOX4_MOUSE NADPH oxidase 4 OS=Mus musculus (M... | 289 | 0.33 | 37.7 | 21 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016175; F:superoxide-generating NADPH oxidase activity; IMP:UniProtKB. | | | | | | | | | | GO:0045453; P:bone resorption; IMP:MGI.::GO:0035051; P:cardiac cell differentiation; IMP:MGI.::GO:0007569; P:cell aging; IMP:UniProtKB.::GO:0000902; P:cell morphogenesis; IMP:UniProtKB.::GO:0071333; P:cellular response to glucose stimulus; IEP:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:2000573; P:positive regulation of DNA biosynthetic process; IMP:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.::GO:0043406; P:positive regulation of MAP kinase activity; IMP:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:UniProtKB.::GO:0042554; P:superoxide anion generation; IDA:UniProtKB. | 57 | Q9VQH2 | 1537 | DUOX_DROME Dual oxidase OS=Drosophila melanog... | 209 | 0.38 | 38.1 | 23 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016174; F:NAD(P)H oxidase activity; IEA:EC.::GO:0004601; F:peroxidase activity; IDA:FlyBase. | | | | | | | | | | GO:0048085; P:adult chitin-containing cuticle pigmentation; IMP:FlyBase.::GO:0019221; P:cytokine-mediated signaling pathway; ISS:UniProtKB.::GO:0042742; P:defense response to bacterium; IMP:FlyBase.::GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW.::GO:0002385; P:mucosal immune response; IMP:FlyBase.::GO:0043066; P:negative regulation of apoptotic process; IMP:FlyBase.::GO:0051591; P:response to cAMP; ISS:UniProtKB.::GO:0035220; P:wing disc development; IMP:FlyBase. | 58 | Q2HXL0 | 938 | RBOHC_SOLTU Respiratory burst oxidase homolog... | 309 | 0.49 | 37.4 | 23 | 37 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0050664; F:oxidoreductase activity, acting on NADH or NADPH, oxygen as acceptor; IEA:InterPro.::GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 59 | Q5R5C5 | 578 | NOX4_PONAB NADPH oxidase 4 OS=Pongo abelii (S... | 317 | 0.91 | 36.6 | 21 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 60 | Q9NPH5 | 578 | NOX4_HUMAN NADPH oxidase 4 OS=Homo sapiens (H... | 302 | 0.91 | 36.6 | 21 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; TAS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0050660; F:flavin adenine dinucleotide binding; TAS:UniProtKB.::GO:0020037; F:heme binding; TAS:UniProtKB.::GO:0072341; F:modified amino acid binding; IDA:UniProtKB.::GO:0016174; F:NAD(P)H oxidase activity; TAS:UniProtKB.::GO:0000166; F:nucleotide binding; TAS:UniProtKB.::GO:0019826; F:oxygen sensor activity; TAS:UniProtKB. | | | | | | | | | | GO:0007569; P:cell aging; ISS:UniProtKB.::GO:0000902; P:cell morphogenesis; ISS:UniProtKB.::GO:0050667; P:homocysteine metabolic process; IDA:UniProtKB.::GO:0006954; P:inflammatory response; TAS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0042554; P:superoxide anion generation; ISS:UniProtKB. | 61 | Q914I2 | 130 | Y050_SIFVH Uncharacterized protein 50 OS=(SIF... | 67 | 1.5 | 33.9 | 33 | 58 | | | | | | | | | | | | | | | | | | | | | |
