Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
Home About FGC Use Cases Species List

UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YLL050C
Length:
143
Number of sequences:
5887
Description:
YLL050C COF1 SGDID:S000003973, Chr XII from 40221-39804,40414-40401, Genome Release 64-1-1, reverse complement, Verified ORF, "Cofilin, promotes actin filament depolarization in a pH-dependent manner; binds both actin monomers and filaments and severs filaments; thought to be regulated by phosphorylation at SER4; ubiquitous and essential in eukaryotes"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61P60981    165   DEST_HUMAN Destrin OS=Homo sapiens (Human). G...1534e-24     96.7     35     56
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
GO:0051014; P:actin filament severing; TAS:ProtInc.::GO:0008154; P:actin polymerization or depolymerization; TAS:ProtInc.
62Q5E9D5    165   DEST_BOVIN Destrin OS=Bos taurus (Bovine). GN...1534e-24     96.7     35     56GO:0030864; C:cortical actin cytoskeleton; ISS:AgBase.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
GO:0006928; P:cellular component movement; ISS:AgBase.::GO:0000910; P:cytokinesis; ISS:AgBase.::GO:0030836; P:positive regulation of actin filament depolymerization; ISS:AgBase.
63P30174    126   ADF_BRANA Actin-depolymerizing factor OS=Bras...1175e-24     95.5     41     62GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
64Q5XHH8    167   COF2_XENLA Cofilin-2 OS=Xenopus laevis (Afric...1379e-24     95.9     39     56GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
65Q9R0P5    165   DEST_MOUSE Destrin OS=Mus musculus (Mouse). G...1539e-24     95.9     35     56GO:0030864; C:cortical actin cytoskeleton; IDA:MGI.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
GO:0006928; P:cellular component movement; IMP:MGI.::GO:0000910; P:cytokinesis; IMP:MGI.::GO:0030836; P:positive regulation of actin filament depolymerization; IMP:MGI.
66Q5U4Y2    167   COF2_XENTR Cofilin-2 OS=Xenopus tropicalis (W...1371e-23     95.9     39     56GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
67Q6NX11    168   COF1_XENTR Cofilin-1 OS=Xenopus tropicalis (W...1442e-22     92.4     35     57GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0051015; F:actin filament binding; ISS:UniProtKB.
GO:0030042; P:actin filament depolymerization; ISS:UniProtKB.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB.
68P45593    168   COF1B_XENLA Cofilin-1-B OS=Xenopus laevis (Af...1444e-22     91.7     34     56GO:0005938; C:cell cortex; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IDA:UniProtKB.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0051015; F:actin filament binding; IDA:UniProtKB.
GO:0030042; P:actin filament depolymerization; IDA:UniProtKB.::GO:0000910; P:cytokinesis; IMP:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB.
69Q54R65    135   COF4_DICDI Cofilin-4 OS=Dictyostelium discoid...1331e-21     89.4     31     60GO:0015629; C:actin cytoskeleton; ISS:dictyBase.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
70P45695    168   COF1A_XENLA Cofilin-1-A OS=Xenopus laevis (Af...1442e-21     89.4     34     57GO:0005938; C:cell cortex; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IDA:UniProtKB.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0051015; F:actin filament binding; IDA:UniProtKB.
GO:0030042; P:actin filament depolymerization; IDA:UniProtKB.::GO:0000910; P:cytokinesis; IMP:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB.
71Q9LZT3    133   ADF11_ARATH Putative actin-depolymerizing fac...1388e-21     87     33     55GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
72Q0D744    146   ADF8_ORYSJ Putative actin-depolymerizing fact...1383e-18     80.9     31     60GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
73Q556H5    138   COF3_DICDI Cofilin-3 OS=Dictyostelium discoid...1300.000000000000003     72.4     27     50GO:0015629; C:actin cytoskeleton; ISS:dictyBase.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
74P86293    143   CADF2_PLAFX Cofilin/actin-depolymerizing fact...1270.0000000000001     67.8     35     54GO:0015629; C:actin cytoskeleton; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003785; F:actin monomer binding; ISS:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0060327; P:cytoplasmic actin-based contraction involved in cell motility; ISS:UniProtKB.
75Q8ID92    143   CADF2_PLAF7 Cofilin/actin-depolymerizing fact...1270.0000000000001     67.8     35     54GO:0015629; C:actin cytoskeleton; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003785; F:actin monomer binding; ISS:UniProtKB.
GO:0008154; P:actin polymerization or depolymerization; ISS:GeneDB_Pfalciparum.::GO:0060327; P:cytoplasmic actin-based contraction involved in cell motility; ISS:UniProtKB.
76Q07750    212   ADF1_CAEEL Actin-depolymerizing factor 1, iso...1530.0000000000002     67.8     31     50GO:0005865; C:striated muscle thin filament; IDA:WormBase.
GO:0051015; F:actin filament binding; IDA:WormBase.
GO:0030042; P:actin filament depolymerization; IDA:WormBase.::GO:0051014; P:actin filament severing; IDA:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0030838; P:positive regulation of actin filament polymerization; IDA:WormBase.::GO:0030240; P:skeletal muscle thin filament assembly; IMP:WormBase.
77Q07749    152   ADF2_CAEEL Actin-depolymerizing factor 2, iso...1400.000000000002     64.3     32     53GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
78Q966T6    143   COF2_DICDI Cofilin-2 OS=Dictyostelium discoid...1350.00000000003     61.2     26     54GO:0015629; C:actin cytoskeleton; IDA:dictyBase.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; ISS:dictyBase.
GO:0030042; P:actin filament depolymerization; IDA:dictyBase.
79P86292    122   CADF1_PLAFX Cofilin/actin-depolymerizing fact...1170.0000000002     58.5     27     52GO:0015629; C:actin cytoskeleton; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003785; F:actin monomer binding; IMP:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; IMP:UniProtKB.::GO:0060327; P:cytoplasmic actin-based contraction involved in cell motility; IMP:UniProtKB.
80Q8I467    122   CADF1_PLAF7 Cofilin/actin-depolymerizing fact...1170.0000000002     58.5     27     52GO:0015629; C:actin cytoskeleton; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003785; F:actin monomer binding; ISS:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0060327; P:cytoplasmic actin-based contraction involved in cell motility; ISS:UniProtKB.
81Q640W2    349   TWF2B_XENLA Twinfilin-2-B OS=Xenopus laevis (...980.000002     49.3     30     53GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
82Q5ZM35    349   TWF2_CHICK Twinfilin-2 OS=Gallus gallus (Chic...940.000009     47.4     31     52GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
83Q68F50    350   TWF1_XENLA Twinfilin-1 OS=Xenopus laevis (Afr...1471.4     32.3     22     44GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
84Q5I082    350   TWF1_XENTR Twinfilin-1 OS=Xenopus tropicalis ...1150.00003     45.8     23     50GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
85Q86IX3    122   COF5_DICDI Cofilin-5 OS=Dictyostelium discoid...1110.0001     42.4     28     47GO:0015629; C:actin cytoskeleton; ISS:dictyBase.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
86Q5R7N2    350   TWF1_PONAB Twinfilin-1 OS=Pongo abelii (Sumat...1480.014     38.1     23     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
87Q7ZXP0    349   TWF2A_XENLA Twinfilin-2-A OS=Xenopus laevis (...950.0002     43.5     27     52GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
88Q6GMH3    347   TWF2_DANRE Twinfilin-2 OS=Danio rerio (Zebraf...690.0003     42.7     26     55GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
89Q12792    350   TWF1_HUMAN Twinfilin-1 OS=Homo sapiens (Human...1480.82     32.7     22     45GO:0015629; C:actin cytoskeleton; ISS:UniProtKB.::GO:0005911; C:cell-cell junction; ISS:BHF-UCL.::GO:0030175; C:filopodium; ISS:BHF-UCL.::GO:0030016; C:myofibril; ISS:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; ISS:BHF-UCL.
GO:0003785; F:actin monomer binding; ISS:BHF-UCL.::GO:0005524; F:ATP binding; IDA:BHF-UCL.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:BHF-UCL.
GO:0043538; P:regulation of actin phosphorylation; IDA:BHF-UCL.::GO:0042989; P:sequestering of actin monomers; ISS:BHF-UCL.
90P20690    150   DEPA_ASTAM Depactin OS=Asterias amurensis (No...1470.0004     41.2     24     51GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
91Q91YR1    350   TWF1_MOUSE Twinfilin-1 OS=Mus musculus (Mouse...1350.0008     41.6     24     49GO:0015629; C:actin cytoskeleton; IDA:UniProtKB.::GO:0005911; C:cell-cell junction; IDA:BHF-UCL.::GO:0030175; C:filopodium; IDA:BHF-UCL.::GO:0030016; C:myofibril; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.
GO:0003785; F:actin monomer binding; IDA:BHF-UCL.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:BHF-UCL.::GO:0004713; F:protein tyrosine kinase activity; IDA:UniProtKB.
GO:0051016; P:barbed-end actin filament capping; IDA:BHF-UCL.::GO:0042989; P:sequestering of actin monomers; IDA:BHF-UCL.
records
Previous ‹‹ ›› Next Total records: 114 61 - 90
Elimate unknown annotation:
Filter for keyword on hit description:
Select upper E value:
Select lower bit score:
Select lower %idenity value:
Select lower %positive value:
Taxonomic division:
Lower limit on hit length:
Lower limit on alignment length::