UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YLL035W

Length:

632

Number of sequences:

5887

Description:

YLL035W GRC3 SGDID:S000003958, Chr XII from 68580-70478, Genome Release 64-1-1, Verified ORF, "Polynucleotide kinase present on rDNA that is required for efficient transcription termination by RNA polymerase I; required for cell growth; mRNA is cell-cycle regulated"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
31	A8WQV9	548	NOL9_CAEBR Polynucleotide 5'-hydroxyl-kinase ...	180	0.00004	50.1	28	46	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051731; F:polynucleotide 5'-hydroxyl-kinase activity; ISS:UniProtKB.
									GO:0006364; P:rRNA processing; ISS:UniProtKB.
32	Q7QJW7	423	CLP1_ANOGA Protein CLP1 homolog OS=Anopheles ...	158	0.00006	49.3	25	44	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
33	Q66JK4	437	CLP1_XENTR Polyribonucleotide 5'-hydroxyl-kin...	164	0.0001	48.5	26	43	GO:0000214; C:tRNA-intron endonuclease complex; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046404; F:ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity; IEA:EC.::GO:0051736; F:ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity; ISS:UniProtKB.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0035087; P:siRNA loading onto RISC involved in RNA interference; ISS:UniProtKB.::GO:0030423; P:targeting of mRNA for destruction involved in RNA interference; ISS:UniProtKB.::GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; ISS:UniProtKB.
34	Q6NS21	439	CLP1_XENLA Polyribonucleotide 5'-hydroxyl-kin...	171	0.0002	48.1	26	44	GO:0000214; C:tRNA-intron endonuclease complex; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046404; F:ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity; IEA:EC.::GO:0051736; F:ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity; ISS:UniProtKB.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0035087; P:siRNA loading onto RISC involved in RNA interference; ISS:UniProtKB.::GO:0030423; P:targeting of mRNA for destruction involved in RNA interference; ISS:UniProtKB.::GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; ISS:UniProtKB.
35	B4KML2	425	CLP1_DROMO Protein CLP1 homolog OS=Drosophila...	140	0.001	45.1	27	46	GO:0000214; C:tRNA-intron endonuclease complex; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; ISS:UniProtKB.
36	B4GGT6	425	CLP1_DROPE Protein CLP1 homolog OS=Drosophila...	154	0.004	43.9	25	42	GO:0000214; C:tRNA-intron endonuclease complex; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; ISS:UniProtKB.
37	Q28ZT4	425	CLP1_DROPS Protein CLP1 homolog OS=Drosophila...	154	0.004	43.9	25	42	GO:0000214; C:tRNA-intron endonuclease complex; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; ISS:UniProtKB.
38	A8PB32	433	CLP1_BRUMA Protein CLP1 homolog OS=Brugia mal...	158	0.004	43.5	23	44	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
39	Q16WA6	424	CLP1_AEDAE Protein CLP1 homolog OS=Aedes aegy...	157	0.005	43.5	24	43	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
40	B4MRZ9	425	CLP1_DROWI Protein CLP1 homolog OS=Drosophila...	153	0.005	43.1	25	42	GO:0000214; C:tRNA-intron endonuclease complex; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; ISS:UniProtKB.
41	E1BPN0	694	NOL9_BOVIN Polynucleotide 5'-hydroxyl-kinase ...	370	0.012	42.4	21	41	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051731; F:polynucleotide 5'-hydroxyl-kinase activity; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0000460; P:maturation of 5.8S rRNA; ISS:UniProtKB.
42	Q5SY16	702	NOL9_HUMAN Polynucleotide 5'-hydroxyl-kinase ...	353	0.014	42.4	21	39	GO:0005730; C:nucleolus; TAS:UniProtKB.
									GO:0005524; F:ATP binding; TAS:UniProtKB.::GO:0051731; F:polynucleotide 5'-hydroxyl-kinase activity; IDA:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0000460; P:maturation of 5.8S rRNA; IMP:UniProtKB.
43	Q3TZX8	714	NOL9_MOUSE Polynucleotide 5'-hydroxyl-kinase ...	411	0.017	42	22	40	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051731; F:polynucleotide 5'-hydroxyl-kinase activity; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0000460; P:maturation of 5.8S rRNA; ISS:UniProtKB.
44	B4QEE3	423	CLP1_DROSI Protein CLP1 homolog OS=Drosophila...	158	0.02	41.6	24	41	GO:0000214; C:tRNA-intron endonuclease complex; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; ISS:UniProtKB.
45	B4HQJ2	423	CLP1_DROSE Protein CLP1 homolog OS=Drosophila...	158	0.02	41.6	24	41	GO:0000214; C:tRNA-intron endonuclease complex; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; ISS:UniProtKB.
46	Q7K284	423	CLP1_DROME Protein CLP1 homolog OS=Drosophila...	158	0.021	41.2	24	41	GO:0000214; C:tRNA-intron endonuclease complex; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; ISS:UniProtKB.
47	B4P4H2	423	CLP1_DROYA Protein CLP1 homolog OS=Drosophila...	153	0.037	40.4	23	42	GO:0000214; C:tRNA-intron endonuclease complex; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; ISS:UniProtKB.
48	Q08685	445	CLP1_YEAST Protein CLP1 OS=Saccharomyces cere...	181	0.042	40.4	25	46	GO:0005849; C:mRNA cleavage factor complex; IPI:SGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0006379; P:mRNA cleavage; IDA:SGD.::GO:0006378; P:mRNA polyadenylation; IDA:SGD.
49	A6ZP88	445	CLP1_YEAS7 Protein CLP1 OS=Saccharomyces cere...	181	0.042	40.4	25	46	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
50	B3MGZ0	425	CLP1_DROAN Protein CLP1 homolog OS=Drosophila...	176	0.073	39.7	25	41	GO:0000214; C:tRNA-intron endonuclease complex; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; ISS:UniProtKB.
51	B3NRK6	423	CLP1_DROER Protein CLP1 homolog OS=Drosophila...	153	0.12	38.9	23	42	GO:0000214; C:tRNA-intron endonuclease complex; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; ISS:UniProtKB.
52	A8X9U4	428	CLP1_CAEBR Protein clpf-1 OS=Caenorhabditis b...	153	0.26	37.7	22	42	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
53	P52874	428	CLP1_CAEEL Protein clpf-1 OS=Caenorhabditis e...	153	0.3	37.7	22	42	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.
54	P61291	254	PSME3_PIG Proteasome activator complex subuni...	154	0.31	37.4	23	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008537; C:proteasome activator complex; IEA:InterPro.
									GO:0070215; F:MDM2 binding; ISS:UniProtKB.::GO:0002039; F:p53 binding; ISS:UniProtKB.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0042981; P:regulation of apoptotic process; ISS:UniProtKB.
55	P61290	254	PSME3_MOUSE Proteasome activator complex subu...	154	0.31	37.4	23	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008537; C:proteasome activator complex; IEA:InterPro.
									GO:0070215; F:MDM2 binding; ISS:UniProtKB.::GO:0002039; F:p53 binding; ISS:UniProtKB.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0042981; P:regulation of apoptotic process; ISS:UniProtKB.
56	Q4R4V3	254	PSME3_MACFA Proteasome activator complex subu...	154	0.31	37.4	23	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008537; C:proteasome activator complex; IEA:InterPro.
									GO:0070215; F:MDM2 binding; ISS:UniProtKB.::GO:0002039; F:p53 binding; ISS:UniProtKB.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0042981; P:regulation of apoptotic process; ISS:UniProtKB.
57	P61289	254	PSME3_HUMAN Proteasome activator complex subu...	154	0.31	37.4	23	45	GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0008537; C:proteasome activator complex; IEA:InterPro.
									GO:0061133; F:endopeptidase activator activity; IDA:UniProtKB.::GO:0070215; F:MDM2 binding; IDA:UniProtKB.::GO:0002039; F:p53 binding; IDA:UniProtKB.
									GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; IDA:UniProtKB.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0061136; P:regulation of proteasomal protein catabolic process; IDA:UniProtKB.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
58	Q5RFD3	254	PSME3_PONAB Proteasome activator complex subu...	154	0.4	37	23	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008537; C:proteasome activator complex; IEA:InterPro.
									GO:0070215; F:MDM2 binding; ISS:UniProtKB.::GO:0002039; F:p53 binding; ISS:UniProtKB.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0042981; P:regulation of apoptotic process; ISS:UniProtKB.
59	B4JVN0	425	CLP1_DROGR Protein CLP1 homolog OS=Drosophila...	140	0.41	37.4	24	44	GO:0000214; C:tRNA-intron endonuclease complex; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; ISS:UniProtKB.
60	Q10299	456	CLP1_SCHPO Protein clp1 OS=Schizosaccharomyce...	77	0.71	36.6	32	51	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005849; C:mRNA cleavage factor complex; ISS:PomBase.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0006379; P:mRNA cleavage; ISS:PomBase.::GO:0006378; P:mRNA polyadenylation; ISS:PomBase.
61	B4MCL6	425	CLP1_DROVI Protein CLP1 homolog OS=Drosophila...	140	0.89	36.2	25	43	GO:0000214; C:tRNA-intron endonuclease complex; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; ISS:UniProtKB.

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