Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKR090W
Length:
706
Number of sequences:
5887
Description:
YKR090W PXL1 SGDID:S000001798, Chr XI from 608946-611066, Genome Release 64-1-1, Verified ORF, "LIM domain-containing protein that localizes to sites of polarized growth, required for selection and/or maintenance of polarized growth sites, may modulate signaling by the GTPases Cdc42p and Rho1p; has similarity to metazoan paxillin"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P36166    706   PXL1_YEAST Paxillin-like protein 1 OS=Sacchar...7060     1460     100     100GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0005737; C:cytoplasm; IDA:SGD.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.
GO:0005094; F:Rho GDP-dissociation inhibitor activity; IGI:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030011; P:maintenance of cell polarity; IMP:SGD.::GO:0035023; P:regulation of Rho protein signal transduction; IPI:SGD.
2Q68G74    356   LHX8_HUMAN LIM/homeobox protein Lhx8 OS=Homo ...1290.0000000001     67.4     31     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
3O35652    367   LHX8_MOUSE LIM/homeobox protein Lhx8 OS=Mus m...1290.0000000003     66.6     31     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008585; P:female gonad development; IMP:MGI.::GO:0021884; P:forebrain neuron development; IGI:MGI.::GO:0007611; P:learning or memory; IMP:MGI.::GO:0042475; P:odontogenesis of dentin-containing tooth; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
4Q09476    413   PXL1_CAEEL Paxillin homolog 1 OS=Caenorhabdit...1080.00007     49.3     26     44GO:0005912; C:adherens junction; IDA:WormBase.::GO:0031430; C:M band; IDA:WormBase.::GO:0002102; C:podosome; IDA:WormBase.::GO:0055120; C:striated muscle dense body; IDA:WormBase.
GO:0017166; F:vinculin binding; IPI:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0061061; P:muscle structure development; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0043050; P:pharyngeal pumping; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.
5A1ZA47    2194   ZASP_DROME PDZ and LIM domain protein Zasp OS...831.7     35.8     31     41GO:0015629; C:actin cytoskeleton; IDA:UniProtKB.::GO:0005927; C:muscle tendon junction; IDA:FlyBase.::GO:0030018; C:Z disc; IDA:FlyBase.
GO:0003779; F:actin binding; IPI:UniProtKB.::GO:0051371; F:muscle alpha-actinin binding; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0061061; P:muscle structure development; IMP:FlyBase.::GO:0001952; P:regulation of cell-matrix adhesion; IMP:UniProtKB.
6Q62920    591   PDLI5_RAT PDZ and LIM domain protein 5 OS=Rat...1880.019     42     25     35GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IDA:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IDA:UniProtKB.::GO:0042805; F:actinin binding; IDA:UniProtKB.::GO:0005080; F:protein kinase C binding; IDA:UniProtKB.::GO:0047485; F:protein N-terminus binding; IMP:RGD.::GO:0030159; F:receptor signaling complex scaffold activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007507; P:heart development; NAS:UniProtKB.::GO:0061001; P:regulation of dendritic spine morphogenesis; IDA:UniProtKB.::GO:0051963; P:regulation of synapse assembly; IDA:UniProtKB.
7Q8MML5    569   PAXB_DICDI Paxillin-B OS=Dictyostelium discoi...1020.21     38.5     26     41GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0032433; C:filopodium tip; IDA:dictyBase.::GO:0005925; C:focal adhesion; IDA:dictyBase.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016339; P:calcium-dependent cell-cell adhesion; IMP:dictyBase.::GO:0016477; P:cell migration; IMP:dictyBase.::GO:0031589; P:cell-substrate adhesion; IMP:dictyBase.::GO:0043326; P:chemotaxis to folate; IMP:dictyBase.::GO:0031154; P:culmination involved in sorocarp development; IMP:dictyBase.::GO:0007109; P:cytokinesis, completion of separation; IMP:dictyBase.
8Q8CI51    591   PDLI5_MOUSE PDZ and LIM domain protein 5 OS=M...1880.025     41.6     25     35GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IDA:MGI.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0051963; P:regulation of synapse assembly; ISS:UniProtKB.
9Q69ZX8    682   ABLM3_MOUSE Actin-binding LIM protein 3 OS=Mu...1340.0000003     57.4     29     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007010; P:cytoskeleton organization; IEA:InterPro.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.
10O94929    683   ABLM3_HUMAN Actin-binding LIM protein 3 OS=Ho...1340.0000003     57.4     29     43GO:0005737; C:cytoplasm; NAS:UniProtKB.
GO:0003779; F:actin binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; IEA:InterPro.
11Q9R1R0    363   LHX6_MOUSE LIM/homeobox protein Lhx6 OS=Mus m...1270.0000005     56.2     30     42GO:0005634; C:nucleus; IDA:MGI.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048469; P:cell maturation; IMP:MGI.::GO:0021853; P:cerebral cortex GABAergic interneuron migration; IMP:MGI.::GO:0021799; P:cerebral cortex radially oriented cell migration; IMP:MGI.::GO:0021800; P:cerebral cortex tangential migration; IMP:MGI.::GO:0021884; P:forebrain neuron development; IGI:MGI.::GO:0021877; P:forebrain neuron fate commitment; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
12Q8K4G5    861   ABLM1_MOUSE Actin-binding LIM protein 1 OS=Mu...1040.0000006     56.6     35     43GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; IDA:MGI.::GO:0007010; P:cytoskeleton organization; IEA:InterPro.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.
13Q8BL65    612   ABLM2_MOUSE Actin-binding LIM protein 2 OS=Mu...980.0000006     56.6     35     45GO:0030016; C:myofibril; IDA:MGI.
GO:0003779; F:actin binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007010; P:cytoskeleton organization; IEA:InterPro.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.
14Q6KC51    612   ABLM2_RAT Actin-binding LIM protein 2 OS=Ratt...980.0000009     55.8     35     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007010; P:cytoskeleton organization; IEA:InterPro.
15Q96HC4    596   PDLI5_HUMAN PDZ and LIM domain protein 5 OS=H...1880.015     42.4     25     35GO:0015629; C:actin cytoskeleton; IDA:LIFEdb.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; ISS:UniProtKB.::GO:0042805; F:actinin binding; ISS:UniProtKB.::GO:0005080; F:protein kinase C binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0051963; P:regulation of synapse assembly; ISS:UniProtKB.
16O14639    778   ABLM1_HUMAN Actin-binding LIM protein 1 OS=Ho...1040.000001     55.8     35     43GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; IEA:InterPro.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0007601; P:visual perception; TAS:ProtInc.
17P49023    591   PAXI_HUMAN Paxillin OS=Homo sapiens (Human). ...970.000001     55.5     32     44GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:BHF-UCL.::GO:0030027; C:lamellipodium; IDA:BHF-UCL.::GO:0005875; C:microtubule associated complex; TAS:ProtInc.
GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0017166; F:vinculin binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0034614; P:cellular response to reactive oxygen species; IEP:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0060396; P:growth hormone receptor signaling pathway; IDA:BHF-UCL.::GO:0006936; P:muscle contraction; TAS:Reactome.::GO:0007172; P:signal complex assembly; TAS:ProtInc.
18Q5R7I1    591   PAXI_PONAB Paxillin OS=Pongo abelii (Sumatran...970.000001     55.5     32     44GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
19Q80W90    388   LHX9_RAT LIM/homeobox protein Lhx9 OS=Rattus ...1930.000001     55.1     24     39GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.
20Q8VI36    591   PAXI_MOUSE Paxillin OS=Mus musculus (Mouse). ...910.000001     55.1     32     44GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0030027; C:lamellipodium; IDA:MGI.
GO:0051435; F:BH4 domain binding; IPI:MGI.::GO:0030159; F:receptor signaling complex scaffold activity; TAS:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000187; P:activation of MAPK activity; IDA:MGI.::GO:0048754; P:branching morphogenesis of a tube; IDA:MGI.::GO:0006928; P:cellular component movement; IMP:MGI.::GO:0007010; P:cytoskeleton organization; IMP:MGI.::GO:0048041; P:focal adhesion assembly; IDA:MGI.::GO:0007229; P:integrin-mediated signaling pathway; IMP:MGI.::GO:0030032; P:lamellipodium assembly; IDA:MGI.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI.
21Q9UPM6    363   LHX6_HUMAN LIM/homeobox protein Lhx6 OS=Homo ...1270.000001     54.7     29     42GO:0005634; C:nucleus; IDA:LIFEdb.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048469; P:cell maturation; ISS:UniProtKB.::GO:0021853; P:cerebral cortex GABAergic interneuron migration; ISS:UniProtKB.::GO:0021799; P:cerebral cortex radially oriented cell migration; ISS:UniProtKB.::GO:0021800; P:cerebral cortex tangential migration; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
22P36198    426   LHX2_RAT LIM/homeobox protein Lhx2 OS=Rattus ...1270.000001     54.7     26     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
23P49024    559   PAXI_CHICK Paxillin OS=Gallus gallus (Chicken...970.000002     55.1     32     44GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
24Q6H8Q1    611   ABLM2_HUMAN Actin-binding LIM protein 2 OS=Ho...980.000002     54.7     34     44GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005737; C:cytoplasm; IDA:HPA.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0003779; F:actin binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; IEA:InterPro.
25Q66H76    586   PAXI_RAT Paxillin OS=Rattus norvegicus (Rat)....910.000002     54.7     32     44GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:RGD.
GO:0005178; F:integrin binding; IPI:RGD.::GO:0019901; F:protein kinase binding; IPI:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
26Q90881    397   LHX9_CHICK LIM/homeobox protein Lhx9 OS=Gallu...1270.000003     53.9     25     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008045; P:motor axon guidance; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0021522; P:spinal cord motor neuron differentiation; IEP:UniProtKB.
27Q62219    461   TGFI1_MOUSE Transforming growth factor beta-1...1050.24     38.1     27     40GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045165; P:cell fate commitment; IGI:MGI.::GO:0030855; P:epithelial cell differentiation; IGI:MGI.::GO:0016331; P:morphogenesis of embryonic epithelium; IMP:MGI.::GO:0045599; P:negative regulation of fat cell differentiation; IGI:MGI.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
28Q9NQ69    397   LHX9_HUMAN LIM/homeobox protein Lhx9 OS=Homo ...1270.000003     53.9     25     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.
29A0JNI8    397   LHX9_BOVIN LIM/homeobox protein Lhx9 OS=Bos t...1270.000003     53.5     25     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.
30Q99PD6    461   TGFI1_RAT Transforming growth factor beta-1-i...1130.22     38.5     27     38GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; TAS:RGD.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0070411; F:I-SMAD binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009408; P:response to heat; IDA:RGD.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
31Q9Z0S2    406   LHX2_MOUSE LIM/homeobox protein Lhx2 OS=Mus m...1270.000004     53.5     25     42GO:0005634; C:nucleus; IDA:MGI.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0000988; F:protein binding transcription factor activity; IPI:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; IMP:MGI.::GO:0009953; P:dorsal/ventral pattern formation; IMP:MGI.::GO:0007498; P:mesoderm development; IMP:MGI.::GO:2000678; P:negative regulation of transcription regulatory region DNA binding; IGI:MGI.::GO:0001843; P:neural tube closure; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0021978; P:telencephalon regionalization; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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