Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKR090W
Length:
706
Number of sequences:
5887
Description:
YKR090W PXL1 SGDID:S000001798, Chr XI from 608946-611066, Genome Release 64-1-1, Verified ORF, "LIM domain-containing protein that localizes to sites of polarized growth, required for selection and/or maintenance of polarized growth sites, may modulate signaling by the GTPases Cdc42p and Rho1p; has similarity to metazoan paxillin"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151P53669    647   LIMK1_RAT LIM domain kinase 1 OS=Rattus norve...820.028     41.6     26     40GO:0044295; C:axonal growth cone; IDA:RGD.::GO:0005794; C:Golgi apparatus; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045773; P:positive regulation of axon extension; ISS:UniProtKB.
152O88609    372   LMX1B_MOUSE LIM homeobox transcription factor...1280.028     41.2     23     42GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043010; P:camera-type eye development; IMP:MGI.::GO:0008219; P:cell death; IMP:MGI.::GO:0008283; P:cell proliferation; IMP:MGI.::GO:0021954; P:central nervous system neuron development; IMP:MGI.::GO:0021587; P:cerebellum morphogenesis; IMP:MGI.::GO:0030199; P:collagen fibril organization; IMP:MGI.::GO:0071542; P:dopaminergic neuron differentiation; IMP:MGI.::GO:0009953; P:dorsal/ventral pattern formation; IEP:UniProtKB.::GO:0030326; P:embryonic limb morphogenesis; NAS:UniProtKB.::GO:0030901; P:midbrain development; IMP:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0035265; P:organ growth; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
153O60663    379   LMX1B_HUMAN LIM homeobox transcription factor...1280.03     40.8     23     42GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009953; P:dorsal/ventral pattern formation; ISS:UniProtKB.::GO:0001701; P:in utero embryonic development; NAS:UniProtKB.::GO:0030182; P:neuron differentiation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
154Q8JFQ2    155   RBTN1_DANRE Rhombotin-1 OS=Danio rerio (Zebra...1380.031     39.3     22     37GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
155Q93052    612   LPP_HUMAN Lipoma-preferred partner OS=Homo sa...1020.033     41.2     27     41GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
156P61969    165   LMO4_MOUSE LIM domain transcription factor LM...1400.034     39.3     23     36GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0001158; F:enhancer sequence-specific DNA binding; IDA:MGI.::GO:0008134; F:transcription factor binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0031333; P:negative regulation of protein complex assembly; IDA:MGI.::GO:0001843; P:neural tube closure; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0050865; P:regulation of cell activation; IMP:MGI.::GO:0042659; P:regulation of cell fate specification; IMP:MGI.::GO:0021527; P:spinal cord association neuron differentiation; IGI:MGI.::GO:0021522; P:spinal cord motor neuron differentiation; IDA:MGI.::GO:0048538; P:thymus development; IGI:MGI.::GO:0006366; P:transcription from RNA polymerase II promoter; IDA:MGI.::GO:0021514; P:ventral spinal cord interneuron differentiation; IDA:MGI.::GO:0003281; P:ventricular septum development; IMP:MGI.
157P61968    165   LMO4_HUMAN LIM domain transcription factor LM...1400.034     39.3     23     36GO:0005667; C:transcription factor complex; ISS:UniProtKB.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001843; P:neural tube closure; ISS:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; ISS:UniProtKB.
158Q3SWZ8    165   LMO4_BOVIN LIM domain transcription factor LM...1400.034     39.3     23     36
GO:0008270; F:zinc ion binding; IEA:InterPro.
159Q60564    369   LMX1B_MESAU LIM homeobox transcription factor...1280.042     40.4     23     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
160Q9JKU8    382   LMX1A_MOUSE LIM homeobox transcription factor...1170.044     40.4     22     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; IMP:MGI.::GO:0021953; P:central nervous system neuron differentiation; IMP:MGI.::GO:0021549; P:cerebellum development; IMP:MGI.::GO:0021542; P:dentate gyrus development; IMP:MGI.::GO:0071542; P:dopaminergic neuron differentiation; IMP:MGI.::GO:0030901; P:midbrain development; IMP:MGI.::GO:0045665; P:negative regulation of neuron differentiation; IMP:MGI.::GO:0001558; P:regulation of cell growth; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
161Q04650    382   LMX1A_MESAU LIM homeobox transcription factor...1170.044     40.4     22     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
162Q8I7C3    657   LASP1_DROME LIM and SH3 domain protein Lasp O...380.06     40.4     45     53GO:0005925; C:focal adhesion; IDA:FlyBase.::GO:0070864; C:sperm individualization complex; IDA:FlyBase.
GO:0003779; F:actin binding; IDA:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007279; P:pole cell formation; IMP:FlyBase.::GO:0045856; P:positive regulation of pole plasm oskar mRNA localization; IMP:FlyBase.::GO:0007291; P:sperm individualization; IMP:FlyBase.
163P53413    377   LMX1B_CHICK LIM/homeobox protein LMX-1.2 OS=G...1220.061     40     24     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
164Q91XD2    341   LIMS2_MOUSE LIM and senescent cell antigen-li...1000.062     40     34     44GO:0005925; C:focal adhesion; IDA:MGI.
GO:0008270; F:zinc ion binding; IEA:InterPro.
165Q924W9    156   RBTN1_MOUSE Rhombotin-1 OS=Mus musculus (Mous...1380.063     38.5     22     37GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
166Q0P5B3    156   RBTN1_BOVIN Rhombotin-1 OS=Bos taurus (Bovine...1380.069     38.5     22     37GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
167Q2KJ33    341   LIMS2_BOVIN LIM and senescent cell antigen-li...1000.076     39.7     33     45GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
168P25800    156   RBTN1_HUMAN Rhombotin-1 OS=Homo sapiens (Huma...1380.079     38.1     22     37GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
169Q292U5    795   ESN_DROPS Protein espinas OS=Drosophila pseud...1230.1     39.7     27     39
GO:0008270; F:zinc ion binding; IEA:InterPro.
170A8DZE6    648   WTIP_DANRE Wilms tumor protein 1-interacting ...1079.7     33.1     25     41GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0014032; P:neural crest cell development; ISS:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
171Q3B8H4    156   RBTN1_XENLA Rhombotin-1 OS=Xenopus laevis (Af...1340.11     37.7     22     35GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
172O14014    969   RGA3_SCHPO Probable Rho-type GTPase-activatin...1210.11     39.7     21     39GO:0000935; C:barrier septum; IDA:PomBase.::GO:0051285; C:cell cortex of cell tip; IDA:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
173Q5FVB2    167   LMO41_XENTR LIM domain transcription factor L...1460.14     37.7     24     36
GO:0003712; F:transcription cofactor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0007498; P:mesoderm development; ISS:UniProtKB.::GO:0045665; P:negative regulation of neuron differentiation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
174Q9U1I1    785   ESN_DROME Protein espinas OS=Drosophila melan...1230.14     39.3     27     39
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070593; P:dendrite self-avoidance; IMP:FlyBase.
175Q801P0    171   LMO4B_XENLA LIM domain transcription factor L...1460.16     37.7     24     36
GO:0003712; F:transcription cofactor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0007498; P:mesoderm development; ISS:UniProtKB.::GO:0045665; P:negative regulation of neuron differentiation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
176Q7Z4I7    341   LIMS2_HUMAN LIM and senescent cell antigen-li...1010.19     38.5     31     48GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0034329; P:cell junction assembly; TAS:Reactome.
177O70400    327   PDLI1_MOUSE PDZ and LIM domain protein 1 OS=M...600.2     38.1     33     48GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0005515; F:protein binding; IPI:MGI.::GO:0003713; F:transcription coactivator activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IDA:MGI.
178Q2QLG8    421   TES_CALJA Testin OS=Callithrix jacchus (White...1130.27     38.1     26     39GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.
179Q8AW92    171   LMO4A_XENLA LIM domain transcription factor L...1400.29     37     24     36
GO:0003712; F:transcription cofactor activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0007498; P:mesoderm development; IMP:UniProtKB.::GO:0045665; P:negative regulation of neuron differentiation; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
180O74360    933   RGA4_SCHPO Probable Rho-type GTPase-activatin...870.29     38.1     25     38GO:0032153; C:cell division site; IDA:PomBase.::GO:0071944; C:cell periphery; IDA:PomBase.::GO:0005737; C:cytoplasm; IDA:PomBase.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070650; P:actin filament bundle distribution; IMP:PomBase.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0060583; P:regulation of actin cortical patch localization; IMP:PomBase.::GO:0032231; P:regulation of actin filament bundle assembly; IMP:PomBase.::GO:0060305; P:regulation of cell diameter; IMP:PomBase.::GO:0007165; P:signal transduction; IEA:InterPro.
181Q9NZU5    365   LMCD1_HUMAN LIM and cysteine-rich domains pro...920.3     37.7     27     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070886; P:positive regulation of calcineurin-NFAT signaling cascade; IMP:UniProtKB.::GO:0010611; P:regulation of cardiac muscle hypertrophy; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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