Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKR090W
Length:
706
Number of sequences:
5887
Description:
YKR090W PXL1 SGDID:S000001798, Chr XI from 608946-611066, Genome Release 64-1-1, Verified ORF, "LIM domain-containing protein that localizes to sites of polarized growth, required for selection and/or maintenance of polarized growth sites, may modulate signaling by the GTPases Cdc42p and Rho1p; has similarity to metazoan paxillin"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121Q292U2    1353   PRIC1_DROPS Protein prickle OS=Drosophila pse...1560.005     44.3     24     34GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009948; P:anterior/posterior axis specification; ISS:UniProtKB.::GO:0001736; P:establishment of planar polarity; ISS:UniProtKB.
122Q80VL3    624   PRIC3_MOUSE Prickle-like protein 3 OS=Mus mus...1170.005     43.9     26     41
GO:0008270; F:zinc ion binding; IEA:InterPro.
123P53411    406   LHX1_CHICK LIM/homeobox protein Lhx1 OS=Gallu...1110.005     43.5     23     42GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0043234; C:protein complex; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0021702; P:cerebellar Purkinje cell differentiation; ISS:UniProtKB.::GO:0021937; P:cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation; ISS:UniProtKB.::GO:0072049; P:comma-shaped body morphogenesis; ISS:UniProtKB.::GO:0009953; P:dorsal/ventral pattern formation; ISS:UniProtKB.::GO:0001705; P:ectoderm formation; ISS:UniProtKB.::GO:0009880; P:embryonic pattern specification; ISS:UniProtKB.::GO:0060059; P:embryonic retina morphogenesis in camera-type eye; ISS:UniProtKB.::GO:0048703; P:embryonic viscerocranium morphogenesis; ISS:UniProtKB.::GO:0001706; P:endoderm formation; ISS:UniProtKB.::GO:0021871; P:forebrain regionalization; ISS:UniProtKB.::GO:0060322; P:head development; ISS:UniProtKB.::GO:0008045; P:motor axon guidance; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0072178; P:nephric duct morphogenesis; ISS:UniProtKB.::GO:0001764; P:neuron migration; ISS:UniProtKB.::GO:0061205; P:paramesonephric duct development; ISS:UniProtKB.::GO:2000744; P:positive regulation of anterior head development; ISS:UniProtKB.::GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0040019; P:positive regulation of embryonic development; ISS:UniProtKB.::GO:2000543; P:positive regulation of gastrulation; ISS:UniProtKB.::GO:2000768; P:positive regulation of nephron tubule epithelial cell differentiation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0009791; P:post-embryonic development; ISS:UniProtKB.::GO:0090009; P:primitive streak formation; ISS:UniProtKB.::GO:0072077; P:renal vesicle morphogenesis; ISS:UniProtKB.::GO:0010842; P:retina layer formation; ISS:UniProtKB.::GO:0072050; P:S-shaped body morphogenesis; ISS:UniProtKB.::GO:0021527; P:spinal cord association neuron differentiation; ISS:UniProtKB.::GO:0021522; P:spinal cord motor neuron differentiation; IEP:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0001657; P:ureteric bud development; ISS:UniProtKB.
124Q8BFW7    613   LPP_MOUSE Lipoma-preferred partner homolog OS...1020.005     43.9     27     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
125Q969G2    390   LHX4_HUMAN LIM/homeobox protein Lhx4 OS=Homo ...1500.006     43.1     19     38GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
126Q5XI07    632   LPP_RAT Lipoma-preferred partner homolog OS=R...1020.007     43.5     27     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
127P53776    390   LHX4_MOUSE LIM/homeobox protein Lhx4 OS=Mus m...1500.007     43.1     19     38GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006916; P:anti-apoptosis; IMP:MGI.::GO:0021526; P:medial motor column neuron differentiation; IGI:MGI.::GO:0008045; P:motor axon guidance; IGI:MGI.::GO:0009887; P:organ morphogenesis; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
128P34416    335   LASP1_CAEEL LIM and SH3 domain protein F42H10...590.007     42.7     37     53
GO:0008270; F:zinc ion binding; IEA:InterPro.
129Q71QF9    831   PRIC1_RAT Prickle-like protein 1 OS=Rattus no...1490.008     43.5     25     37GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0008134; F:transcription factor binding; IPI:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006606; P:protein import into nucleus; IDA:RGD.
130Q1LZ94    158   RBTN2_BOVIN Rhombotin-2 OS=Bos taurus (Bovine...1330.008     41.2     25     41
GO:0008270; F:zinc ion binding; IEA:InterPro.
131A6NIX2    430   WTIP_HUMAN Wilms tumor protein 1-interacting ...1060.008     42.7     25     43GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0000932; C:cytoplasmic mRNA processing body; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0035195; P:gene silencing by miRNA; IMP:MGI.::GO:0035331; P:negative regulation of hippo signaling cascade; IDA:UniProtKB.::GO:2000637; P:positive regulation of gene silencing by miRNA; IMP:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0001666; P:response to hypoxia; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
132Q5M8V8    158   RBTN2_XENTR Rhombotin-2 OS=Xenopus tropicalis...1330.008     41.2     25     41GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.
133P25801    158   RBTN2_MOUSE Rhombotin-2 OS=Mus musculus (Mous...1330.008     41.2     25     41GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0043234; C:protein complex; IPI:UniProtKB.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035162; P:embryonic hemopoiesis; IGI:MGI.::GO:0045647; P:negative regulation of erythrocyte differentiation; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.
134Q9PTJ3    159   RBTN2_DANRE Rhombotin-2 OS=Danio rerio (Zebra...1350.008     41.2     26     41GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001568; P:blood vessel development; IMP:ZFIN.::GO:0035162; P:embryonic hemopoiesis; IMP:ZFIN.::GO:0030218; P:erythrocyte differentiation; IGI:ZFIN.
135P25791    158   RBTN2_HUMAN Rhombotin-2 OS=Homo sapiens (Huma...1330.008     41.2     25     41GO:0005667; C:transcription factor complex; IDA:BHF-UCL.
GO:0043425; F:bHLH transcription factor binding; IPI:BHF-UCL.::GO:0048037; F:cofactor binding; IPI:BHF-UCL.::GO:0070888; F:E-box binding; IDA:BHF-UCL.::GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.::GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:BHF-UCL.::GO:0001190; F:RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; IDA:BHF-UCL.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0097067; P:cellular response to thyroid hormone stimulus; IDA:UniProtKB.::GO:0042789; P:mRNA transcription from RNA polymerase II promoter; IDA:BHF-UCL.
136Q04584    542   ZYX_CHICK Zyxin OS=Gallus gallus (Chicken). G...930.094     39.7     26     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
137Q28FG2    833   PRIC1_XENTR Prickle-like protein 1 OS=Xenopus...1160.011     42.7     26     40GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009948; P:anterior/posterior axis specification; ISS:UniProtKB.::GO:0060027; P:convergent extension involved in gastrulation; ISS:UniProtKB.::GO:0001736; P:establishment of planar polarity; ISS:UniProtKB.
138Q32L23    638   LIMK2_BOVIN LIM domain kinase 2 OS=Bos taurus...1260.011     42.7     25     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
139Q5F464    604   LPP_CHICK Lipoma-preferred partner homolog OS...1020.012     42.4     26     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
140P53667    647   LIMK1_HUMAN LIM domain kinase 1 OS=Homo sapie...1030.014     42.4     24     42GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0043005; C:neuron projection; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IDA:BHF-UCL.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; TAS:Reactome.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051444; P:negative regulation of ubiquitin-protein ligase activity; IDA:BHF-UCL.::GO:0032233; P:positive regulation of actin filament bundle assembly; IDA:BHF-UCL.::GO:0045773; P:positive regulation of axon extension; ISS:UniProtKB.::GO:0007266; P:Rho protein signal transduction; TAS:ProtInc.
141P52944    327   PDLI1_RAT PDZ and LIM domain protein 1 OS=Rat...600.015     41.6     35     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001666; P:response to hypoxia; IEP:RGD.
142Q8IR79    1257   LIMK1_DROME LIM domain kinase 1 OS=Drosophila...820.017     42.4     28     44GO:0005826; C:actomyosin contractile ring; IDA:UniProtKB.::GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0048749; P:compound eye development; IGI:FlyBase.::GO:0001737; P:establishment of imaginal disc-derived wing hair orientation; IMP:FlyBase.::GO:0050770; P:regulation of axonogenesis; IMP:FlyBase.::GO:0051124; P:synaptic growth at neuromuscular junction; IMP:FlyBase.
143Q2TBC4    344   PRIC4_HUMAN Prickle-like protein 4 OS=Homo sa...920.018     41.6     28     39GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
144Q54NW4    553   LIMB_DICDI LIM domain-containing protein B OS...1095.8     33.9     30     41GO:0005938; C:cell cortex; IDA:dictyBase.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; ISS:dictyBase.
GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0007155; P:cell adhesion; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0031154; P:culmination involved in sorocarp development; IMP:dictyBase.
145Q90Z06    835   PRI1A_XENLA Prickle-like protein 1-A OS=Xenop...1160.021     42     26     39GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009948; P:anterior/posterior axis specification; IMP:UniProtKB.::GO:0060027; P:convergent extension involved in gastrulation; IMP:UniProtKB.::GO:0001736; P:establishment of planar polarity; IMP:UniProtKB.
146P52889    399   LHX5_DANRE LIM/homeobox protein Lhx5 OS=Danio...840.023     41.6     23     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001654; P:eye development; IGI:ZFIN.::GO:0030900; P:forebrain development; IDA:ZFIN.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
147Q90WV2    832   PRI1B_XENLA Prickle-like protein 1-B OS=Xenop...1160.024     41.6     26     39GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009948; P:anterior/posterior axis specification; ISS:UniProtKB.::GO:0060027; P:convergent extension involved in gastrulation; ISS:UniProtKB.
148Q6DJ06    165   LMO42_XENTR LIM domain transcription factor L...1400.025     39.7     23     36
GO:0003712; F:transcription cofactor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0007498; P:mesoderm development; ISS:UniProtKB.::GO:0045665; P:negative regulation of neuron differentiation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
149Q8VEE1    365   LMCD1_MOUSE LIM and cysteine-rich domains pro...940.026     41.2     29     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0070886; P:positive regulation of calcineurin-NFAT signaling cascade; IMP:UniProtKB.::GO:0010611; P:regulation of cardiac muscle hypertrophy; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
150Q9VY77    728   AJUBA_DROME LIM domain-containing protein jub...1300.86     36.6     25     38GO:0005912; C:adherens junction; IDA:FlyBase.
GO:0003779; F:actin binding; ISS:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035329; P:hippo signaling cascade; IMP:FlyBase.::GO:0045572; P:positive regulation of imaginal disc growth; IMP:FlyBase.
151P53669    647   LIMK1_RAT LIM domain kinase 1 OS=Rattus norve...820.028     41.6     26     40GO:0044295; C:axonal growth cone; IDA:RGD.::GO:0005794; C:Golgi apparatus; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045773; P:positive regulation of axon extension; ISS:UniProtKB.
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