Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKR089C
Length:
910
Number of sequences:
5887
Description:
YKR089C TGL4 SGDID:S000001797, Chr XI from 608365-605633, Genome Release 64-1-1, reverse complement, Verified ORF, "Multifunctional triacylglycerol lipase, steryl ester hydrolase, and Ca2+-independent phospholipase A2; catalyzes acyl-CoA dependent acylation of LPA to PA; required with Tgl3p for timely bud formation; phosphorylated and activated by Cdc28p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q6ZV29    1317   PLPL7_HUMAN Patatin-like phospholipase domain...450.2     39.3     42     58GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
GO:0006629; P:lipid metabolic process; IEA:InterPro.
32Q91F63    290   463L_IIV6 Probable lipid hydrolase 463L OS=In...2190.23     38.1     27     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
33Q5BK26    1349   PLPL7_RAT Patatin-like phospholipase domain-c...2150.26     38.9     25     40GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0004091; F:carboxylesterase activity; IMP:RGD.
GO:0006629; P:lipid metabolic process; IEA:InterPro.
34Q5RDS0    1365   PLPL6_PONAB Neuropathy target esterase OS=Pon...450.45     38.1     40     60GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004622; F:lysophospholipase activity; IEA:EC.
GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0046470; P:phosphatidylcholine metabolic process; IEA:InterPro.
35Q8IY17    1366   PLPL6_HUMAN Neuropathy target esterase OS=Hom...450.48     38.1     40     60GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004622; F:lysophospholipase activity; IEA:EC.
GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0046470; P:phosphatidylcholine metabolic process; IEA:InterPro.
36Q3TRM4    1355   PLPL6_MOUSE Neuropathy target esterase OS=Mus...450.5     38.1     40     60GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004622; F:lysophospholipase activity; IEA:EC.
GO:0001525; P:angiogenesis; IMP:MGI.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0009887; P:organ morphogenesis; IMP:MGI.::GO:0046470; P:phosphatidylcholine metabolic process; IEA:InterPro.
37A2AJ88    1352   PLPL7_MOUSE Patatin-like phospholipase domain...2150.58     37.7     24     38GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
GO:0006629; P:lipid metabolic process; IEA:InterPro.
38P27570    1239   TOP2_CRIFA DNA topoisomerase 2 OS=Crithidia f...560.59     37.7     36     50GO:0005694; C:chromosome; IEA:InterPro.::GO:0020023; C:kinetoplast; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
39Q6FKJ1    1728   NTE1_CANGA Lysophospholipase NTE1 OS=NRRL Y-6...450.62     37.7     40     58GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004622; F:lysophospholipase activity; IEA:EC.
GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0046470; P:phosphatidylcholine metabolic process; IEA:InterPro.
40P0CP36    1621   NTE1_CRYNJ Lysophospholipase NTE1 OS=ATCC MYA...540.79     37.4     39     52GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004622; F:lysophospholipase activity; IEA:EC.
GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0046470; P:phosphatidylcholine metabolic process; IEA:InterPro.
41P0CP37    1621   NTE1_CRYNB Lysophospholipase NTE1 OS=(Filobas...540.79     37.4     39     52GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004622; F:lysophospholipase activity; IEA:EC.
GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0046470; P:phosphatidylcholine metabolic process; IEA:InterPro.
42P0A643    583   Y2594_MYCBO Uncharacterized NTE family protei...600.85     37     37     55
GO:0004622; F:lysophospholipase activity; IEA:InterPro.
GO:0046470; P:phosphatidylcholine metabolic process; IEA:InterPro.
43P0A642    583   Y2565_MYCTU Uncharacterized NTE family protei...600.85     37     37     55GO:0005829; C:cytosol; IDA:MTBBASE.
GO:0004622; F:lysophospholipase activity; IEA:InterPro.
GO:0046470; P:phosphatidylcholine metabolic process; IEA:InterPro.
44P12531    1221   TOP2_TRYBB DNA topoisomerase 2 OS=Trypanosoma...560.98     37     32     52GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
45Q9USJ4    1316   NTE1_SCHPO Lysophospholipase NTE1 OS=Schizosa...481.2     36.6     44     56GO:0005789; C:endoplasmic reticulum membrane; NAS:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004091; F:carboxylesterase activity; ISS:PomBase.::GO:0004622; F:lysophospholipase activity; ISS:PomBase.
GO:0034638; P:phosphatidylcholine catabolic process; ISS:PomBase.
46Q04958    1679   NTE1_YEAST Lysophospholipase NTE1 OS=Saccharo...451.3     36.6     38     58GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004091; F:carboxylesterase activity; IDA:SGD.::GO:0004622; F:lysophospholipase activity; IDA:SGD.
GO:0034638; P:phosphatidylcholine catabolic process; IMP:SGD.::GO:0071071; P:regulation of phospholipid biosynthetic process; IMP:SGD.
47O94724    108   YCFC_SCHPO Uncharacterized protein C1393.12 O...771.8     33.5     29     53GO:0005737; C:cytoplasm; IDA:PomBase.
GO:0033554; P:cellular response to stress; IEP:PomBase.
48P67099    360   Y1092_MYCBO Uncharacterized NTE family protei...532.3     35.4     40     51
GO:0004622; F:lysophospholipase activity; IEA:InterPro.
GO:0046470; P:phosphatidylcholine metabolic process; IEA:InterPro.
49P67098    360   Y1063_MYCTU Uncharacterized NTE family protei...532.3     35.4     40     51
GO:0004622; F:lysophospholipase activity; IEA:InterPro.
GO:0046470; P:phosphatidylcholine metabolic process; IEA:InterPro.
50P22733    627   LACY_LACDA Lactose permease OS=20081). GN=lac...862.4     35.4     29     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0005351; F:sugar:hydrogen symporter activity; IEA:InterPro.
GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:InterPro.::GO:0006814; P:sodium ion transport; IEA:InterPro.
51Q17771    542   NHR35_CAEEL Nuclear hormone receptor family m...1062.7     35.4     24     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
52Q756Z0    1522   NTE1_ASHGO Lysophospholipase NTE1 OS=Y-1056) ...453.3     35.4     36     58GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004622; F:lysophospholipase activity; IEA:EC.
GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0046470; P:phosphatidylcholine metabolic process; IEA:InterPro.
53Q4PF83    1883   NTE1_USTMA Lysophospholipase NTE1 OS=Ustilago...543.6     35     35     56GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004622; F:lysophospholipase activity; IEA:EC.
GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0046470; P:phosphatidylcholine metabolic process; IEA:InterPro.
54B4SQC8    443   EX7L_STRM5 Exodeoxyribonuclease 7 large subun...1533.9     34.7     28     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0009318; C:exodeoxyribonuclease VII complex; IEA:InterPro.
GO:0008855; F:exodeoxyribonuclease VII activity; IEA:EC.
GO:0006308; P:DNA catabolic process; IEA:InterPro.
55Q8PTK1    568   DNLI2_METMA DNA ligase 2 OS=JCM 11833 / OCM 8...1093.9     34.7     28     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003910; F:DNA ligase (ATP) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051103; P:DNA ligation involved in DNA repair; IEA:InterPro.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
56P16284    738   PECA1_HUMAN Platelet endothelial cell adhesio...1198.7     33.9     24     50GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0031092; C:platelet alpha granule membrane; TAS:Reactome.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0008037; P:cell recognition; TAS:ProtInc.::GO:0050904; P:diapedesis; IDA:UniProtKB.::GO:0072011; P:glomerular endothelium development; IEP:UniProtKB.::GO:0006909; P:phagocytosis; IDA:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0002576; P:platelet degranulation; TAS:Reactome.::GO:0007165; P:signal transduction; TAS:ProtInc.
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