UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YKR069W

Length:

593

Number of sequences:

5887

Description:

YKR069W MET1 SGDID:S000001777, Chr XI from 571612-573393, Genome Release 64-1-1, Verified ORF, "S-adenosyl-L-methionine uroporphyrinogen III transmethylase, involved in the biosynthesis of siroheme, a prosthetic group used by sulfite reductase; required for sulfate assimilation and methionine biosynthesis"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
91	A8GKQ1	467	CYSG2_SERP5 Siroheme synthase 2 OS=Serratia p...	237	5e-33	135	35	53
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
92	Q88FT3	463	CYSG_PSEPK Siroheme synthase OS=Pseudomonas p...	272	8e-33	134	33	53
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
93	Q7WB57	473	CYSG_BORPA Siroheme synthase OS=Bordetella pa...	260	8e-33	134	36	52
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
94	Q7WMM4	473	CYSG_BORBR Siroheme synthase OS=(Alcaligenes ...	260	8e-33	134	36	52
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
95	A9HZV6	474	CYSG_BORPD Siroheme synthase OS=Bordetella pe...	232	1e-32	134	39	53
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
96	Q0A812	481	CYSG_ALHEH Siroheme synthase OS=Alkalilimnico...	433	2e-32	134	26	43
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
97	Q6F8G6	457	CYSG_ACIAD Siroheme synthase OS=Acinetobacter...	252	3e-32	133	33	52
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
98	A5WEG6	487	CYSG_PSYWF Siroheme synthase OS=Psychrobacter...	261	3e-32	133	34	51
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
99	Q2Y6L7	472	CYSG_NITMU Siroheme synthase OS=Nitrosospira ...	185	0.12	38.9	22	43
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
100	Q5NRM4	471	CYSG_ZYMMO Siroheme synthase OS=Zymomonas mob...	244	5e-32	132	34	53
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
101	Q02NA3	465	CYSG_PSEAB Siroheme synthase OS=Pseudomonas a...	249	5e-32	132	35	52
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
102	A4XUX3	462	CYSG_PSEMY Siroheme synthase OS=Pseudomonas m...	238	7e-32	132	34	53
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
103	Q820Q4	475	CYSG_NITEU Siroheme synthase OS=Nitrosomonas ...	258	9e-32	131	33	51
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
104	Q1IBC9	463	CYSG_PSEE4 Siroheme synthase OS=Pseudomonas e...	234	2e-31	130	35	53
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
105	B1JBD9	464	CYSG_PSEPW Siroheme synthase OS=Pseudomonas p...	287	2e-31	130	32	52
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
106	Q6CZS0	459	CYSG2_ERWCT Siroheme synthase 2 OS=BAA-672) (...	81	0.3	37.7	27	52
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
107	A7MJ67	471	CYSG1_CROS8 Siroheme synthase 1 OS=Cronobacte...	246	2e-31	130	35	52
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
108	Q0VQ05	461	CYSG_ALCBS Siroheme synthase OS=Alcanivorax b...	192	0.42	37	25	42
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
109	Q0AHC1	476	CYSG_NITEC Siroheme synthase OS=Nitrosomonas ...	239	7e-31	129	33	54
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
110	A6VPZ6	476	CYSG_ACTSZ Siroheme synthase OS=Actinobacillu...	259	1e-30	129	33	52
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
111	P42437	483	NASF_BACSU Uroporphyrinogen-III C-methyltrans...	238	2e-30	128	34	51
									GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:InterPro.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.::GO:0004852; F:uroporphyrinogen-III synthase activity; IEA:InterPro.
									GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
112	A1WWP8	484	CYSG1_HALHL Siroheme synthase 1 OS=halophila ...	441	2e-30	128	27	43
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
113	Q2KWB0	461	CYSG_BORA1 Siroheme synthase OS=Bordetella av...	240	3e-30	127	37	52
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
114	Q15YU1	462	CYSG_PSEA6 Siroheme synthase OS=Pseudoalterom...	254	4e-30	126	33	52
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
115	Q3JCS0	468	CYSG_NITOC Siroheme synthase OS=Nitrosococcus...	234	5e-30	126	34	54
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
116	Q493N1	474	CYSG_BLOPB Siroheme synthase OS=Blochmannia p...	234	5e-30	126	35	51
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
117	Q4FSU1	549	CYSG_PSYA2 Siroheme synthase OS=Psychrobacter...	525	7e-30	127	27	41
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
118	Q58375	242	SUMT_METJA Uroporphyrinogen-III C-methyltrans...	226	7e-30	122	34	52
									GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:InterPro.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.
119	Q1H3L5	467	CYSG_METFK Siroheme synthase OS=Methylobacill...	161	0.59	36.6	25	43
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
120	Q87AI5	478	CYSG_XYLFT Siroheme synthase OS=Xylella fasti...	243	2e-29	125	35	52
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
121	B2I985	478	CYSG_XYLF2 Siroheme synthase OS=Xylella fasti...	243	2e-29	125	35	52
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.

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