UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YKR069W

Length:

593

Number of sequences:

5887

Description:

YKR069W MET1 SGDID:S000001777, Chr XI from 571612-573393, Genome Release 64-1-1, Verified ORF, "S-adenosyl-L-methionine uroporphyrinogen III transmethylase, involved in the biosynthesis of siroheme, a prosthetic group used by sulfite reductase; required for sulfate assimilation and methionine biosynthesis"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
121	B2I985	478	CYSG_XYLF2 Siroheme synthase OS=Xylella fasti...	243	2e-29	125	35	52
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
122	Q3ILQ9	473	CYSG_PSEHT Siroheme synthase OS=Pseudoalterom...	234	4e-29	124	30	53
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
123	Q7N8L2	470	CYSG_PHOLL Siroheme synthase OS=Photorhabdus ...	254	5e-29	124	34	52
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
124	B0U4X0	476	CYSG_XYLFM Siroheme synthase OS=Xylella fasti...	239	6e-29	123	35	52
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
125	O34744	257	SUMT_BACSU Uroporphyrinogen-III C-methyltrans...	241	7e-29	119	33	49
									GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:InterPro.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.
126	Q1QAX7	523	CYSG_PSYCK Siroheme synthase OS=Psychrobacter...	240	7e-29	124	35	50
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
127	Q1LTP4	462	CYSG_BAUCH Siroheme synthase OS=Baumannia cic...	145	0.002	44.7	21	50
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
128	Q6D1A4	480	CYSG1_ERWCT Siroheme synthase 1 OS=BAA-672) (...	259	1e-28	122	32	50
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
129	Q606C9	474	CYSG_METCA Siroheme synthase OS=Methylococcus...	250	2e-28	122	32	51
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
130	A1SRP9	472	CYSG_PSYIN Siroheme synthase OS=Psychromonas ...	236	4e-28	121	36	54
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
131	A1JJS8	472	CYSG1_YERE8 Siroheme synthase 1 OS=Yersinia e...	257	5e-28	120	32	49
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
132	P21631	280	SUMT_PSEDE Uroporphyrinogen-III C-methyltrans...	258	6e-28	117	31	46
									GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:InterPro.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.
133	Q7NZV7	470	CYSG_CHRVO Siroheme synthase OS=NBRC 12614 / ...	273	7e-28	120	32	50
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
134	Q7VQG9	461	CYSG_BLOFL Siroheme synthase OS=Blochmannia f...	238	8e-28	120	35	50
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
135	Q66EC9	472	CYSG1_YERPS Siroheme synthase 1 OS=Yersinia p...	255	1e-27	120	35	51
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
136	A4TPZ1	472	CYSG2_YERPP Siroheme synthase 2 OS=Yersinia p...	255	1e-27	120	35	51
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
137	Q1CLS2	472	CYSG1_YERPN Siroheme synthase 1 OS=Yersinia p...	255	1e-27	120	35	51
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
138	A7FLY4	472	CYSG1_YERP3 Siroheme synthase 1 OS=Yersinia p...	255	1e-27	119	35	51
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
139	Q9PF46	476	CYSG_XYLFA Siroheme synthase OS=Xylella fasti...	244	1e-27	119	34	51
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
140	A1WYD5	495	CYSG2_HALHL Siroheme synthase 2 OS=halophila ...	80	0.000003	53.5	31	59
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
141	A6TD45	471	CYSG1_KLEP7 Siroheme synthase 1 OS=78578). GN...	257	3e-27	118	33	50
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
142	C4LAG5	468	CYSG_TOLAT Siroheme synthase OS=Tolumonas aue...	238	4e-27	118	36	54
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
143	P57500	473	CYSG_BUCAI Siroheme synthase OS=(Acyrthosipho...	262	4e-27	118	33	50
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
144	A0KP37	470	CYSG2_AERHH Siroheme synthase 2 OS=Aeromonas ...	256	4e-27	118	36	53
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
145	P29928	238	SUMT_BACME Uroporphyrinogen-III C-methyltrans...	237	4e-27	114	31	49
									GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:InterPro.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.
146	Q2NVN0	471	CYSG_SODGM Siroheme synthase OS=Sodalis gloss...	238	4e-27	118	34	54
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
147	Q6LM67	469	CYSG_PHOPR Siroheme synthase OS=Photobacteriu...	234	4e-27	118	34	54
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
148	Q55749	263	SUMT_SYNY3 Uroporphyrinogen-III C-methyltrans...	239	5e-27	114	32	49
									GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:InterPro.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.
149	A8G9Y3	476	CYSG1_SERP5 Siroheme synthase 1 OS=Serratia p...	204	9e-26	114	38	52
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
150	P42451	243	SUMT_SYNE7 Uroporphyrinogen-III C-methyltrans...	243	3e-25	109	33	50
									GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:InterPro.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.
151	Q9I2W4	245	SUMT_PSEAE Uroporphyrinogen-III C-methyltrans...	239	4e-25	108	31	49
									GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:InterPro.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.

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