UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YKR069W

Length:

593

Number of sequences:

5887

Description:

YKR069W MET1 SGDID:S000001777, Chr XI from 571612-573393, Genome Release 64-1-1, Verified ORF, "S-adenosyl-L-methionine uroporphyrinogen III transmethylase, involved in the biosynthesis of siroheme, a prosthetic group used by sulfite reductase; required for sulfate assimilation and methionine biosynthesis"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P36150	593	SUMT_YEAST Uroporphyrinogen-III C-methyltrans...	593	0	1212	100	100	GO:0005622; C:intracellular; IC:SGD.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:InterPro.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IDA:SGD.
									GO:0009086; P:methionine biosynthetic process; IMP:SGD.::GO:0019354; P:siroheme biosynthetic process; IGI:SGD.::GO:0000103; P:sulfate assimilation; NAS:SGD.
2	O74468	496	SUMT_SCHPO Probable uroporphyrinogen-III C-me...	496	2e-98	315	38	53
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:InterPro.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; ISS:PomBase.
									GO:0009086; P:methionine biosynthetic process; ISS:PomBase.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
3	A0KQJ4	468	CYSG3_AERHH Siroheme synthase 3 OS=Aeromonas ...	236	2e-37	148	37	54
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
4	A4WFH1	457	CYSG_ENT38 Siroheme synthase OS=Enterobacter ...	232	3e-37	147	38	57
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
5	Q87ZT0	464	CYSG_PSESM Siroheme synthase OS=Pseudomonas s...	244	6e-37	147	38	55
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
6	A1AVU5	472	CYSG_RUTMC Siroheme synthase OS=Ruthia magnif...	187	0.21	38.1	22	44
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
7	Q4ZRL6	464	CYSG_PSEU2 Siroheme synthase OS=Pseudomonas s...	244	9e-37	146	38	55
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
8	Q31VS0	457	CYSG_SHIBS Siroheme synthase OS=Shigella boyd...	232	1e-36	145	36	56
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
9	B2U3H4	457	CYSG_SHIB3 Siroheme synthase OS=Shigella boyd...	232	1e-36	145	36	56
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
10	Q3YWQ3	457	CYSG_SHISS Siroheme synthase OS=Shigella sonn...	232	1e-36	145	36	56
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
11	Q83JB3	457	CYSG_SHIFL Siroheme synthase OS=Shigella flex...	232	1e-36	145	36	56
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
12	Q0SZU8	457	CYSG_SHIF8 Siroheme synthase OS=Shigella flex...	232	1e-36	145	36	56
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
13	B6I2S7	457	CYSG_ECOSE Siroheme synthase OS=Escherichia c...	232	1e-36	145	36	56
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
14	B7M1S1	457	CYSG_ECO8A Siroheme synthase OS=Escherichia c...	232	1e-36	145	36	56
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
15	A7ZSP4	457	CYSG_ECO24 Siroheme synthase OS=Escherichia c...	232	1e-36	145	36	56
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
16	B7NDX8	457	CYSG_ECOLU Siroheme synthase OS=Escherichia c...	232	1e-36	145	36	56
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
17	B5YTS6	457	CYSG_ECO5E Siroheme synthase OS=Escherichia c...	232	1e-36	145	36	56
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
18	B7NMD7	457	CYSG_ECO7I Siroheme synthase OS=Escherichia c...	232	1e-36	145	36	56
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
19	B1LHG9	457	CYSG_ECOSM Siroheme synthase OS=Escherichia c...	232	1e-36	145	36	56
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
20	P0AEA8	457	CYSG_ECOLI Siroheme synthase OS=Escherichia c...	232	1e-36	145	36	56
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
21	B1IP96	457	CYSG_ECOLC Siroheme synthase OS=Escherichia c...	232	1e-36	145	36	56
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
22	A8A5H5	457	CYSG_ECOHS Siroheme synthase OS=Escherichia c...	232	1e-36	145	36	56
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
23	B1X716	457	CYSG_ECODH Siroheme synthase OS=Escherichia c...	232	1e-36	145	36	56
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
24	C4ZUM4	457	CYSG_ECOBW Siroheme synthase OS=Escherichia c...	232	1e-36	145	36	56
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
25	P0AEA9	457	CYSG_ECO57 Siroheme synthase OS=Escherichia c...	232	1e-36	145	36	56
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
26	B7L4P2	457	CYSG_ECO55 Siroheme synthase OS=Escherichia c...	232	1e-36	145	36	56
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
27	Q59294	504	HEM4_CLOJO Porphyrin biosynthesis protein hem...	244	2e-36	145	38	55
									GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:InterPro.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.::GO:0004852; F:uroporphyrinogen-III synthase activity; IEA:EC.
									GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
28	A6TF07	457	CYSG2_KLEP7 Siroheme synthase 2 OS=78578). GN...	174	1.1	35.8	22	45
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
29	C5BGP8	461	CYSG_EDWI9 Siroheme synthase OS=Edwardsiella ...	259	5e-36	144	34	52
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
30	B5F8J0	459	CYSG_SALA4 Siroheme synthase OS=Salmonella ag...	259	6e-36	144	35	52
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
31	B5FJQ1	457	CYSG_SALDC Siroheme synthase OS=Salmonella du...	259	6e-36	144	35	52
									GO:0051287; F:NAD binding; IEA:InterPro.::GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:EC.::GO:0051266; F:sirohydrochlorin ferrochelatase activity; IEA:EC.::GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IEA:EC.
									GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.::GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.

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