Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKR038C
Length:
386
Number of sequences:
5887
Description:
YKR038C KAE1 SGDID:S000001746, Chr XI from 513159-511999, Genome Release 64-1-1, reverse complement, Verified ORF, "Highly conserved ATPase of HSP70/DnaK family; component of the EKC/KEOPS complex with Bud32p, Cgi121p, Pcc1p, and Gon7p; EKC/KEOPS complex is required for t6A tRNA modification and may have roles in telomere maintenance and transcription"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P36132    386   KAE1_YEAST Probable tRNA threonylcarbamoylade...3860     805     100     100GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IDA:SGD.::GO:0000408; C:EKC/KEOPS complex; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0031490; F:chromatin DNA binding; IDA:SGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IPI:SGD.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0000723; P:telomere maintenance; IPI:SGD.::GO:0070525; P:threonylcarbamoyladenosine metabolic process; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
2Q6CJ48    385   KAE1_KLULA Probable tRNA threonylcarbamoylade...3860     685     84     91GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
3Q758R9    385   KAE1_ASHGO Probable tRNA threonylcarbamoylade...3860     675     82     91GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
4Q6FLI1    373   KAE1_CANGA Probable tRNA threonylcarbamoylade...3860     613     78     85GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
5Q6BNC5    373   KAE1_DEBHA Probable tRNA threonylcarbamoylade...3770     565     75     82GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
6Q5A6A4    372   KAE1_CANAL Probable tRNA threonylcarbamoylade...3770     558     73     83GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
7Q6CCZ5    356   KAE1_YARLI Probable tRNA threonylcarbamoylade...3702e-177     505     69     78GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
8Q0TVK3    352   KAE1_PHANO Probable tRNA threonylcarbamoylade...3708e-169     483     66     76GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
9Q0CH39    361   KAE1_ASPTN Probable tRNA threonylcarbamoylade...3777e-166     476     65     75GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
10Q4WDE9    352   KAE1_ASPFU Probable tRNA threonylcarbamoylade...3703e-165     474     66     75GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
11A1CM94    364   KAE1_ASPCL Probable tRNA threonylcarbamoylade...3801e-164     473     65     75GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
12Q4I5V2    363   KAE1_GIBZE Probable tRNA threonylcarbamoylade...3711e-163     470     64     75GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
13Q2U9B5    358   KAE1_ASPOR Probable tRNA threonylcarbamoylade...3741e-163     470     64     74GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
14Q5AYR1    363   KAE1_EMENI Probable tRNA threonylcarbamoylade...3795e-160     461     64     75GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
15Q1E406    371   KAE1_COCIM Probable tRNA threonylcarbamoylade...3862e-159     459     64     73GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
16O94637    346   KAE1_SCHPO Probable tRNA threonylcarbamoylade...3707e-159     457     63     74GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0000408; C:EKC/KEOPS complex; ISS:PomBase.::GO:0000790; C:nuclear chromatin; ISS:PomBase.
GO:0031490; F:chromatin DNA binding; ISS:PomBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; ISS:PomBase.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:PomBase.::GO:0006508; P:proteolysis; ISS:PomBase.::GO:0000723; P:telomere maintenance; ISS:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
17Q7S745    354   KAE1_NEUCR Probable tRNA threonylcarbamoylade...3806e-157     453     61     72GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
18Q9VV41    347   OSGEP_DROME Probable tRNA threonylcarbamoylad...3694e-153     443     60     75
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
19Q2GXN6    356   KAE1_CHAGB Probable tRNA threonylcarbamoylade...3698e-152     440     62     72GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
20Q7SYR1    335   OSGEP_XENLA Probable tRNA threonylcarbamoylad...3702e-150     435     59     74
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
21P0CQ14    398   KAE1_CRYNJ Probable tRNA threonylcarbamoylade...3713e-150     437     60     74GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
22P0CQ15    398   KAE1_CRYNB Probable tRNA threonylcarbamoylade...3713e-150     437     60     74GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
23Q9NPF4    335   OSGEP_HUMAN Probable tRNA threonylcarbamoylad...3681e-149     434     61     73
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
24Q0VCI1    335   OSGEP_BOVIN Probable tRNA threonylcarbamoylad...3681e-149     434     61     72
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
25Q8BWU5    335   OSGEP_MOUSE Probable tRNA threonylcarbamoylad...3683e-148     430     61     71
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
26A7SXZ6    335   OSGEP_NEMVE Probable tRNA threonylcarbamoylad...3684e-142     414     59     72
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
27Q9WVS2    322   OSGEP_RAT Probable tRNA threonylcarbamoyladen...3425e-140     409     62     73
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
28Q55GU1    336   OSGEP_DICDI Probable tRNA threonylcarbamoylad...3688e-138     404     58     72
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
29Q8SQQ3    331   KAE1_ENCCU Probable tRNA threonylcarbamoylade...3702e-130     384     55     67GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
30Q58530    535   KAE1B_METJA Probable bifunctional tRNA threon...3683e-91     290     45     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
31O27476    534   KAE1B_METTH Probable bifunctional tRNA threon...3686e-91     290     45     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
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