Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKR036C
Length:
643
Number of sequences:
5887
Description:
YKR036C CAF4 SGDID:S000001744, Chr XI from 510633-508702, Genome Release 64-1-1, reverse complement, Verified ORF, "WD40 repeat-containing protein associated with the CCR4-NOT complex, interacts in a Ccr4p-dependent manner with Ssn2p; also interacts with Fis1p, Mdv1p and Dnm1p and plays a role in mitochondrial fission"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
391Q95RJ9    700   EBI_DROME F-box-like/WD repeat-containing pro...3060.00000003     60.8     21     39GO:0005700; C:polytene chromosome; IDA:FlyBase.::GO:0017053; C:transcriptional repressor complex; IGI:FlyBase.
GO:0003682; F:chromatin binding; IDA:FlyBase.::GO:0070491; F:repressing transcription factor binding; IPI:FlyBase.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0022416; P:chaeta development; IMP:FlyBase.::GO:0042676; P:compound eye cone cell fate commitment; TAS:FlyBase.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IPI:GOC.::GO:0007219; P:Notch signaling pathway; TAS:FlyBase.::GO:0042461; P:photoreceptor cell development; IMP:FlyBase.::GO:0031065; P:positive regulation of histone deacetylation; IDA:FlyBase.::GO:0045572; P:positive regulation of imaginal disc growth; IMP:FlyBase.::GO:0045747; P:positive regulation of Notch signaling pathway; IDA:FlyBase.::GO:0042058; P:regulation of epidermal growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0030162; P:regulation of proteolysis; TAS:FlyBase.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.::GO:0035220; P:wing disc development; IMP:FlyBase.
392O42469    767   TLE1_XENLA Transducin-like enhancer protein 1...1540.009     43.1     25     38GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
393Q04724    770   TLE1_HUMAN Transducin-like enhancer protein 1...3430.0009     46.2     24     37
GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:BHF-UCL.::GO:0008134; F:transcription factor binding; IDA:UniProtKB.
GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; NAS:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
394Q5ZME8    513   SMU1_CHICK WD40 repeat-containing protein SMU...833.6     34.3     27     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
395P62881    395   GBB5_MOUSE Guanine nucleotide-binding protein...2600.0005     46.6     20     37GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:MGI.
396P79147    340   GBB3_CANFA Guanine nucleotide-binding protein...2480.000005     52.4     22     43GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
397O13282    643   TAF5_SCHPO Transcription initiation factor TF...2370.0002     48.1     21     41GO:0005829; C:cytosol; IDA:PomBase.::GO:0000124; C:SAGA complex; IDA:PomBase.::GO:0005669; C:transcription factor TFIID complex; IDA:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.
GO:0006338; P:chromatin remodeling; IC:PomBase.::GO:0016573; P:histone acetylation; IC:PomBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; IC:PomBase.
398O88879    1249   APAF_MOUSE Apoptotic protease-activating fact...2510.14     39.3     20     39GO:0005634; C:nucleus; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI.
GO:0043531; F:ADP binding; IEA:InterPro.::GO:0016505; F:apoptotic protease activator activity; IPI:MGI.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:MGI.
GO:0006952; P:defense response; IEA:InterPro.::GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; IGI:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0001843; P:neural tube closure; IMP:MGI.::GO:0051402; P:neuron apoptotic process; IGI:MGI.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
399O24456    327   GBLPA_ARATH Guanine nucleotide-binding protei...2510.0003     47     22     42GO:0009507; C:chloroplast; IDA:TAIR.::GO:0022626; C:cytosolic ribosome; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005515; F:protein binding; IPI:TAIR.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0071215; P:cellular response to abscisic acid stimulus; IEP:TAIR.::GO:0006417; P:regulation of translation; IGI:TAIR.::GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0042254; P:ribosome biogenesis; IGI:TAIR.::GO:0009845; P:seed germination; IGI:TAIR.
400Q10051    492   PRP19_CAEEL Pre-mRNA-processing factor 19 hom...2740.00000003     60.1     23     41GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.::GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
GO:0040002; P:collagen and cuticulin-based cuticle development; IMP:WormBase.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
401Q676U5    607   A16L1_HUMAN Autophagy-related protein 16-1 OS...1950.00002     51.2     25     42GO:0005776; C:autophagic vacuole; ISS:UniProtKB.::GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0000045; P:autophagic vacuole assembly; NAS:UniProtKB.::GO:0051260; P:protein homooligomerization; NAS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
402B0W517    425   WDR12_CULQU Ribosome biogenesis protein WDR12...3060.00000003     59.7     24     43GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0070545; C:PeBoW complex; ISS:UniProtKB.
GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ISS:UniProtKB.
403O43017    380   SWD3_SCHPO Set1 complex component swd3 OS=Sch...1000.00006     49.3     30     56GO:0005829; C:cytosol; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.::GO:0048188; C:Set1C/COMPASS complex; IDA:PomBase.
GO:0006338; P:chromatin remodeling; IC:PomBase.::GO:0051568; P:histone H3-K4 methylation; IMP:PomBase.
404Q6TMK6    340   GBB1_CRIGR Guanine nucleotide-binding protein...2500.00001     51.2     24     43
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
405Q20059    683   WDR48_CAEEL WD repeat-containing protein 48 h...3130.00000004     60.5     24     42
406Q0DYP5    435   C3H17_ORYSJ Zinc finger CCCH domain-containin...2250.0000007     55.8     23     44
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
407Q9FLX9    473   NLE1_ARATH Notchless protein homolog OS=Arabi...1300.032     40.8     25     44GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:TAIR.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
408P49027    334   GBLPA_ORYSJ Guanine nucleotide-binding protei...3220.016     41.6     20     39GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0050832; P:defense response to fungus; IMP:UniProtKB.::GO:0060267; P:positive regulation of respiratory burst; IMP:UniProtKB.
409O13166    761   TLE2_DANRE Protein groucho-2 OS=Danio rerio (...700.048     40.4     31     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
410Q62441    773   TLE4_MOUSE Transducin-like enhancer protein 4...3430.0003     47.8     24     38GO:0005634; C:nucleus; IC:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0070491; F:repressing transcription factor binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IDA:MGI.
411Q04727    773   TLE4_HUMAN Transducin-like enhancer protein 4...3450.0003     47.8     23     38GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
412P17343    340   GBB1_CAEEL Guanine nucleotide-binding protein...700.76     36.2     33     50
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0000132; P:establishment of mitotic spindle orientation; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0040013; P:negative regulation of locomotion; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0035046; P:pronuclear migration; IMP:WormBase.::GO:0046662; P:regulation of oviposition; IMP:WormBase.
413Q61ZF6    340   GBB1_CAEBR Guanine nucleotide-binding protein...700.76     36.2     33     50
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
414P25635    923   PWP2_YEAST Periodic tryptophan protein 2 OS=S...2990.000005     53.5     21     41GO:0005737; C:cytoplasm; IDA:SGD.::GO:0034388; C:Pwp2p-containing subcomplex of 90S preribosome; IDA:SGD.::GO:0032040; C:small-subunit processome; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0030515; F:snoRNA binding; IPI:SGD.
GO:0000910; P:cytokinesis; IMP:SGD.::GO:0000480; P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0000472; P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0030010; P:establishment of cell polarity; IMP:SGD.
415P40968    455   PRP17_YEAST Pre-mRNA-processing factor 17 OS=...3240.003     43.9     22     39GO:0005681; C:spliceosomal complex; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:SGD.::GO:0000350; P:generation of catalytic spliceosome for second transesterification step; IMP:SGD.::GO:0000389; P:nuclear mRNA 3'-splice site recognition; IGI:SGD.::GO:0000348; P:nuclear mRNA branch site recognition; IGI:SGD.
416O42478    772   TLE4_XENLA Transducin-like enhancer protein 4...3440.0003     47.8     24     37GO:0017053; C:transcriptional repressor complex; IPI:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IGI:UniProtKB.
GO:0001707; P:mesoderm formation; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
417Q39190    479   PRL2_ARATH Protein pleiotropic regulator PRL2...410.63     36.6     39     63GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:TAIR.
GO:0005515; F:protein binding; IPI:TAIR.
418Q9JIT3    764   TLE3_RAT Transducin-like enhancer protein 3 O...700.039     40.8     31     49GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0005515; F:protein binding; IPI:BHF-UCL.
GO:0006355; P:regulation of transcription, DNA-dependent; IDA:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
419Q13685    434   AAMP_HUMAN Angio-associated migratory cell pr...2280.01     42.4     25     41GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008201; F:heparin binding; TAS:ProtInc.
GO:0001525; P:angiogenesis; NAS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0010595; P:positive regulation of endothelial cell migration; ISS:UniProtKB.::GO:0014909; P:smooth muscle cell migration; IEP:UniProtKB.
420Q8C0J2    607   A16L1_MOUSE Autophagy-related protein 16-1 OS...1950.000003     53.9     25     42GO:0000421; C:autophagic vacuole membrane; IDA:MGI.::GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:MGI.
GO:0000045; P:autophagic vacuole assembly; TAS:MGI.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
421Q61011    340   GBB3_MOUSE Guanine nucleotide-binding protein...2480.000002     53.9     22     43GO:0005834; C:heterotrimeric G-protein complex; TAS:MGI.
GO:0003924; F:GTPase activity; TAS:MGI.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:MGI.
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