Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKR036C
Length:
643
Number of sequences:
5887
Description:
YKR036C CAF4 SGDID:S000001744, Chr XI from 510633-508702, Genome Release 64-1-1, reverse complement, Verified ORF, "WD40 repeat-containing protein associated with the CCR4-NOT complex, interacts in a Ccr4p-dependent manner with Ssn2p; also interacts with Fis1p, Mdv1p and Dnm1p and plays a role in mitochondrial fission"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q969H0    707   FBXW7_HUMAN F-box/WD repeat-containing protei...1710.00000002     61.2     25     46GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0043234; C:protein complex; IDA:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0034644; P:cellular response to UV; IDA:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0055088; P:lipid homeostasis; ISS:BHF-UCL.::GO:0032876; P:negative regulation of DNA endoreduplication; IMP:BHF-UCL.::GO:2000346; P:negative regulation of hepatocyte proliferation; ISS:BHF-UCL.::GO:0045746; P:negative regulation of Notch signaling pathway; ISS:BHF-UCL.::GO:2000639; P:negative regulation of SREBP-mediated signaling pathway; ISS:BHF-UCL.::GO:0010868; P:negative regulation of triglyceride biosynthetic process; ISS:BHF-UCL.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0045741; P:positive regulation of epidermal growth factor-activated receptor activity; IDA:BHF-UCL.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:BHF-UCL.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0050821; P:protein stabilization; IDA:BHF-UCL.::GO:0016567; P:protein ubiquitination; IDA:UniProtKB.::GO:0010883; P:regulation of lipid storage; ISS:BHF-UCL.::GO:0032880; P:regulation of protein localization; ISS:BHF-UCL.::GO:0006974; P:response to DNA damage stimulus; IDA:UniProtKB.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0007062; P:sister chromatid cohesion; IMP:BHF-UCL.::GO:0001944; P:vasculature development; TAS:BHF-UCL.
32Q8YRI1    1526   YY46_NOSS1 Uncharacterized WD repeat-containi...3202e-18     94     25     44
33Q8VBV4    629   FBXW7_MOUSE F-box/WD repeat-containing protei...1430.00000003     60.1     27     48GO:0005783; C:endoplasmic reticulum; IDA:MGI.::GO:0005794; C:Golgi apparatus; IDA:MGI.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB.
GO:0005515; F:protein binding; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
GO:0007219; P:Notch signaling pathway; IDA:MGI.::GO:0016567; P:protein ubiquitination; ISS:UniProtKB.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
34Q3Y8L7    446   WDR69_CHLRE Outer row dynein assembly protein...3293e-16     85.1     25     40GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0035086; C:flagellar axoneme; IEA:UniProtKB-SubCell.::GO:0005932; C:microtubule basal body; IEA:UniProtKB-SubCell.
35Q09855    506   POF11_SCHPO F-box/WD repeat-containing protei...1380.0008     46.2     21     46GO:0005829; C:cytosol; IDA:PomBase.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.
36Q5SRY7    542   FBW1B_MOUSE F-box/WD repeat-containing protei...1170.0003     47.4     24     53GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0042347; P:negative regulation of NF-kappaB import into nucleus; IMP:UniProtKB.::GO:0042753; P:positive regulation of circadian rhythm; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
37Q9UKB1    542   FBW1B_HUMAN F-box/WD repeat-containing protei...1170.0001     48.9     25     53GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0042753; P:positive regulation of circadian rhythm; ISS:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
38Q5BK30    415   WDR69_RAT Outer row dynein assembly protein 1...2360.0000000000005     75.1     27     44GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
39Q91854    518   TRCB_XENLA Beta-TrCP OS=Xenopus laevis (Afric...1160.0002     48.1     24     50
GO:0046983; F:protein dimerization activity; IEA:InterPro.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
40Q7Z4S6    1674   KI21A_HUMAN Kinesin-like protein KIF21A OS=Ho...2290.0009     46.2     26     41GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003777; F:microtubule motor activity; IEA:InterPro.
GO:0007018; P:microtubule-based movement; IEA:InterPro.
41Q9Y297    605   FBW1A_HUMAN F-box/WD repeat-containing protei...1160.0003     47.4     23     50GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0046983; F:protein dimerization activity; IEA:InterPro.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; TAS:BHF-UCL.::GO:0045879; P:negative regulation of smoothened signaling pathway; TAS:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; IMP:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
42Q8N136    415   WDR69_HUMAN Outer row dynein assembly protein...1120.0002     47.4     24     48GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
43Q3ULA2    605   FBW1A_MOUSE F-box/WD repeat-containing protei...1160.0003     47.8     23     50GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB.
GO:0008013; F:beta-catenin binding; IDA:BHF-UCL.::GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0045309; F:protein phosphorylated amino acid binding; IDA:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:BHF-UCL.
GO:0060444; P:branching involved in mammary gland duct morphogenesis; IMP:MGI.::GO:0071407; P:cellular response to organic cyclic compound; IDA:MGI.::GO:0033598; P:mammary gland epithelial cell proliferation; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0042753; P:positive regulation of circadian rhythm; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:BHF-UCL.::GO:0051726; P:regulation of cell cycle; IMP:MGI.::GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; IMP:MGI.::GO:0061136; P:regulation of proteasomal protein catabolic process; IDA:MGI.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
44O14170    703   POP2_SCHPO WD repeat-containing protein pop2 ...1820.002     45.4     24     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005635; C:nuclear envelope; IDA:PomBase.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:PomBase.
GO:0030674; F:protein binding, bridging; IPI:PomBase.
GO:0032876; P:negative regulation of DNA endoreduplication; IMP:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:PomBase.
45Q8YTC2    1258   Y2800_NOSS1 Uncharacterized WD repeat-contain...2110.000003     54.3     22     45
GO:0043531; F:ADP binding; IEA:InterPro.
GO:0006952; P:defense response; IEA:InterPro.
46Q9QXL2    1672   KI21A_MOUSE Kinesin-like protein KIF21A OS=Mu...2280.0009     46.6     26     41GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003777; F:microtubule motor activity; IEA:InterPro.
GO:0007018; P:microtubule-based movement; IEA:InterPro.
47Q1LV15    415   WDR69_DANRE Outer row dynein assembly protein...2850.000000000000001     83.2     25     42GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
GO:0070286; P:axonemal dynein complex assembly; IMP:UniProtKB.::GO:0060285; P:ciliary cell motility; IMP:UniProtKB.::GO:0060271; P:cilium morphogenesis; IMP:UniProtKB.::GO:0007368; P:determination of left/right symmetry; IMP:UniProtKB.
48B6Q4Z5    660   SCONB_PENMQ Probable E3 ubiquitin ligase comp...4354e-20     98.6     23     42
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
49Q09990    665   LIN23_CAEEL F-box/WD repeat-containing protei...1160.0002     48.1     24     53GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0005634; C:nucleus; IDA:WormBase.
GO:0046983; F:protein dimerization activity; IEA:InterPro.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0048812; P:neuron projection morphogenesis; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.
50Q4R8E7    415   WDR69_MACFA Outer row dynein assembly protein...1120.0001     48.1     25     47GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
51Q93794    587   SEL10_CAEEL F-box/WD repeat-containing protei...1700.00000003     60.1     22     46GO:0030424; C:axon; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:WormBase.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0046660; P:female sex differentiation; IMP:UniProtKB.::GO:0045746; P:negative regulation of Notch signaling pathway; IGI:UniProtKB.
52Q0P593    415   WDR69_BOVIN Outer row dynein assembly protein...2180.000000005     62.4     24     42GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
53Q5FWQ6    415   WDR69_XENLA Outer row dynein assembly protein...2818e-17     86.7     26     41GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
54P87053    605   POF1_SCHPO F-box/WD repeat-containing protein...1763e-17     89.4     30     52GO:0000152; C:nuclear ubiquitin ligase complex; ISS:PomBase.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:PomBase.
GO:0030674; F:protein binding, bridging; IPI:PomBase.
GO:0071276; P:cellular response to cadmium ion; IEP:PomBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IPI:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.
55Q6P2Y2    415   WDR69_XENTR Outer row dynein assembly protein...2818e-17     86.7     25     41GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
56Q61FW2    589   SEL10_CAEBR F-box/WD repeat-containing protei...1700.000001     55.5     22     46
57C5FP68    674   SCONB_ARTOC Probable E3 ubiquitin ligase comp...1210.00003     50.8     25     46
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
58Q00808    1356   HETE1_PODAS Vegetative incompatibility protei...1550.00001     52.4     26     46
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
59D4AM37    663   SCONB_ARTBC Probable E3 ubiquitin ligase comp...1210.000006     53.1     26     46
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
60D4D8P3    663   SCONB_TRIVH Probable E3 ubiquitin ligase comp...1210.000007     52.8     26     46
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
61B8M7Q5    667   SCONB_TALSN Probable E3 ubiquitin ligase comp...1230.00002     51.2     27     49
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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