Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKR026C
Length:
305
Number of sequences:
5887
Description:
YKR026C GCN3 SGDID:S000001734, Chr XI from 489655-488738, Genome Release 64-1-1, reverse complement, Verified ORF, "Alpha subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a positive regulator of GCN4 expression"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P14741    305   EI2BA_YEAST Translation initiation factor eIF...3050     629     100     100GO:0005851; C:eukaryotic translation initiation factor 2B complex; IDA:SGD.::GO:0032045; C:guanyl-nucleotide exchange factor complex; IDA:SGD.
GO:0030234; F:enzyme regulator activity; IMP:SGD.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0003743; F:translation initiation factor activity; IDA:SGD.
GO:0006446; P:regulation of translational initiation; IDA:SGD.
2Q9USP0    341   EI2BA_SCHPO Translation initiation factor eIF...3255e-94     288     45     65GO:0005829; C:cytosol; IDA:PomBase.::GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:RefGenome.::GO:0003743; F:translation initiation factor activity; ISS:PomBase.
GO:0002183; P:cytoplasmic translational initiation; NAS:PomBase.::GO:0006446; P:regulation of translational initiation; ISS:RefGenome.
3Q5RAR0    305   EI2BA_PONAB Translation initiation factor eIF...3101e-71     230     42     59
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
4Q14232    305   EI2BA_HUMAN Translation initiation factor eIF...3101e-71     230     42     59GO:0005829; C:cytosol; TAS:Reactome.::GO:0005851; C:eukaryotic translation initiation factor 2B complex; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0051716; P:cellular response to stimulus; IDA:UniProtKB.::GO:0014003; P:oligodendrocyte development; IMP:UniProtKB.::GO:0006446; P:regulation of translational initiation; IBA:RefGenome.::GO:0009749; P:response to glucose stimulus; ISS:UniProtKB.::GO:0009408; P:response to heat; ISS:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; ISS:UniProtKB.
5Q0IIF2    305   EI2BA_BOVIN Translation initiation factor eIF...3102e-71     229     42     59GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:RefGenome.
GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:RefGenome.::GO:0003743; F:translation initiation factor activity; ISS:RefGenome.
GO:0006446; P:regulation of translational initiation; ISS:RefGenome.
6Q4R4V8    305   EI2BA_MACFA Translation initiation factor eIF...3104e-71     228     42     58GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.
7Q54I81    321   EI2BA_DICDI Translation initiation factor eIF...3101e-69     225     39     58GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0003743; F:translation initiation factor activity; IBA:RefGenome.
GO:0006446; P:regulation of translational initiation; IBA:RefGenome.
8Q99LC8    305   EI2BA_MOUSE Translation initiation factor eIF...3106e-69     223     40     58GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005515; F:protein binding; IPI:MGI.::GO:0003743; F:translation initiation factor activity; IBA:RefGenome.
GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.
9Q64270    305   EI2BA_RAT Translation initiation factor eIF-2...2971e-68     222     42     59GO:0005850; C:eukaryotic translation initiation factor 2 complex; IDA:RGD.::GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0019003; F:GDP binding; IDA:RGD.::GO:0005525; F:GTP binding; IMP:RGD.::GO:0003743; F:translation initiation factor activity; IDA:RGD.
GO:0032057; P:negative regulation of translational initiation in response to stress; IMP:RGD.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0009749; P:response to glucose stimulus; IDA:UniProtKB.::GO:0009408; P:response to heat; IDA:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; IDA:UniProtKB.
10P34604    305   EI2BA_CAEEL Probable translation initiation f...3095e-53     181     36     53GO:0005851; C:eukaryotic translation initiation factor 2B complex; IBA:RefGenome.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0003743; F:translation initiation factor activity; IBA:RefGenome.
GO:0006446; P:regulation of translational initiation; IBA:RefGenome.
11O28242    313   EI2B2_ARCFU Putative translation initiation f...2709e-31     122     30     48
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
12Q57586    308   EI2B2_METJA Putative translation initiation f...2707e-30     120     31     50
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
13O57947    324   EI2B2_PYRHO Putative translation initiation f...2679e-28     114     30     49
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
14Q9V281    324   EI2B2_PYRAB Putative translation initiation f...2772e-27     113     27     48
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
15Q8U3J1    276   EI2BL_PYRFU Putative translation initiation f...2158e-27     110     30     53
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
16Q8U4G6    324   EI2B2_PYRFU Putative translation initiation f...2802e-26     110     29     48
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
17D4GV73    323   EI2B2_HALVD Putative translation initiation f...2583e-26     110     28     49
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
18Q9UYB6    276   EI2BL_PYRAB Putative translation initiation f...2161e-23     101     30     50
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
19O58185    276   EI2BL_PYRHO Putative translation initiation f...2472e-23     101     28     47
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
20Q54EY2    388   EI2BB_DICDI Translation initiation factor eIF...2001e-21     97.1     32     52GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:dictyBase.
GO:0005525; F:GTP binding; IC:dictyBase.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0003743; F:translation initiation factor activity; IBA:RefGenome.
GO:0006446; P:regulation of translational initiation; ISS:dictyBase.
21Q54FM3    619   EI2BD_DICDI Translation initiation factor eIF...2923e-21     97.8     27     47GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:dictyBase.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0003743; F:translation initiation factor activity; ISS:dictyBase.
GO:0045947; P:negative regulation of translational initiation; IBA:RefGenome.
22Q90511    355   EI2BB_TAKRU Translation initiation factor eIF...2271e-19     90.9     28     48GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:RefGenome.::GO:0003743; F:translation initiation factor activity; ISS:RefGenome.
GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.::GO:0042552; P:myelination; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0006446; P:regulation of translational initiation; ISS:RefGenome.
23A5D1G8    364   MTNA_PELTS Methylthioribose-1-phosphate isome...2882e-19     90.5     30     42
GO:0046523; F:S-methyl-5-thioribose-1-phosphate isomerase activity; IEA:EC.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
24Q99LD9    351   EI2BB_MOUSE Translation initiation factor eIF...2185e-19     89     28     50GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0003743; F:translation initiation factor activity; IBA:RefGenome.
GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.::GO:0042552; P:myelination; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.::GO:0006446; P:regulation of translational initiation; IBA:RefGenome.
25O29877    339   MTNA_ARCFU Putative methylthioribose-1-phosph...2667e-19     88.6     27     46
GO:0046523; F:S-methyl-5-thioribose-1-phosphate isomerase activity; IEA:EC.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
26P49770    351   EI2BB_HUMAN Translation initiation factor eIF...1978e-19     88.6     29     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0005851; C:eukaryotic translation initiation factor 2B complex; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0051716; P:cellular response to stimulus; IDA:UniProtKB.::GO:0042552; P:myelination; IMP:UniProtKB.::GO:0014003; P:oligodendrocyte development; IMP:UniProtKB.::GO:0001541; P:ovarian follicle development; IMP:UniProtKB.::GO:0006446; P:regulation of translational initiation; TAS:UniProtKB.::GO:0009749; P:response to glucose stimulus; ISS:UniProtKB.::GO:0009408; P:response to heat; ISS:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; ISS:UniProtKB.
27Q5E9B4    351   EI2BB_BOVIN Translation initiation factor eIF...1971e-18     88.2     29     51GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:RefGenome.::GO:0003743; F:translation initiation factor activity; ISS:RefGenome.
GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.::GO:0042552; P:myelination; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.::GO:0006446; P:regulation of translational initiation; ISS:RefGenome.
28Q57896    329   MTNA_METJA Putative methylthioribose-1-phosph...2711e-18     87.4     30     46
GO:0046523; F:S-methyl-5-thioribose-1-phosphate isomerase activity; IEA:EC.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
29Q62818    351   EI2BB_RAT Translation initiation factor eIF-2...2184e-18     86.7     27     49GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003743; F:translation initiation factor activity; IBA:RefGenome.
GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.::GO:0042552; P:myelination; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.::GO:0006446; P:regulation of translational initiation; IBA:RefGenome.::GO:0009749; P:response to glucose stimulus; IDA:UniProtKB.::GO:0009408; P:response to heat; IDA:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; IDA:UniProtKB.
30A4J678    346   MTNA_DESRM Methylthioribose-1-phosphate isome...2751e-17     85.1     28     47
GO:0046523; F:S-methyl-5-thioribose-1-phosphate isomerase activity; IEA:EC.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
31B0TH58    345   MTNA_HELMI Methylthioribose-1-phosphate isome...2761e-17     84.7     31     44
GO:0046523; F:S-methyl-5-thioribose-1-phosphate isomerase activity; IEA:EC.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
records
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