rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P14741 | 305 | EI2BA_YEAST Translation initiation factor eIF... | 305 | 0 | 629 | 100 | 100 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; IDA:SGD.::GO:0032045; C:guanyl-nucleotide exchange factor complex; IDA:SGD. | | | | | | | | | | GO:0030234; F:enzyme regulator activity; IMP:SGD.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0003743; F:translation initiation factor activity; IDA:SGD. | | | | | | | | | | GO:0006446; P:regulation of translational initiation; IDA:SGD. | 2 | Q9USP0 | 341 | EI2BA_SCHPO Translation initiation factor eIF... | 325 | 5e-94 | 288 | 45 | 65 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:RefGenome.::GO:0003743; F:translation initiation factor activity; ISS:PomBase. | | | | | | | | | | GO:0002183; P:cytoplasmic translational initiation; NAS:PomBase.::GO:0006446; P:regulation of translational initiation; ISS:RefGenome. | 3 | Q5RAR0 | 305 | EI2BA_PONAB Translation initiation factor eIF... | 310 | 1e-71 | 230 | 42 | 59 | | | | | | | | | | | GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 4 | Q14232 | 305 | EI2BA_HUMAN Translation initiation factor eIF... | 310 | 1e-71 | 230 | 42 | 59 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005851; C:eukaryotic translation initiation factor 2B complex; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051716; P:cellular response to stimulus; IDA:UniProtKB.::GO:0014003; P:oligodendrocyte development; IMP:UniProtKB.::GO:0006446; P:regulation of translational initiation; IBA:RefGenome.::GO:0009749; P:response to glucose stimulus; ISS:UniProtKB.::GO:0009408; P:response to heat; ISS:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; ISS:UniProtKB. | 5 | Q0IIF2 | 305 | EI2BA_BOVIN Translation initiation factor eIF... | 310 | 2e-71 | 229 | 42 | 59 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:RefGenome. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:RefGenome.::GO:0003743; F:translation initiation factor activity; ISS:RefGenome. | | | | | | | | | | GO:0006446; P:regulation of translational initiation; ISS:RefGenome. | 6 | Q4R4V8 | 305 | EI2BA_MACFA Translation initiation factor eIF... | 310 | 4e-71 | 228 | 42 | 58 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB. | | | | | | | | | | GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB. | 7 | Q54I81 | 321 | EI2BA_DICDI Translation initiation factor eIF... | 310 | 1e-69 | 225 | 39 | 58 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0003743; F:translation initiation factor activity; IBA:RefGenome. | | | | | | | | | | GO:0006446; P:regulation of translational initiation; IBA:RefGenome. | 8 | Q99LC8 | 305 | EI2BA_MOUSE Translation initiation factor eIF... | 310 | 6e-69 | 223 | 40 | 58 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005515; F:protein binding; IPI:MGI.::GO:0003743; F:translation initiation factor activity; IBA:RefGenome. | | | | | | | | | | GO:0014003; P:oligodendrocyte development; ISS:UniProtKB. | 9 | Q64270 | 305 | EI2BA_RAT Translation initiation factor eIF-2... | 297 | 1e-68 | 222 | 42 | 59 | GO:0005850; C:eukaryotic translation initiation factor 2 complex; IDA:RGD.::GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0019003; F:GDP binding; IDA:RGD.::GO:0005525; F:GTP binding; IMP:RGD.::GO:0003743; F:translation initiation factor activity; IDA:RGD. | | | | | | | | | | GO:0032057; P:negative regulation of translational initiation in response to stress; IMP:RGD.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0009749; P:response to glucose stimulus; IDA:UniProtKB.::GO:0009408; P:response to heat; IDA:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; IDA:UniProtKB. | 10 | P34604 | 305 | EI2BA_CAEEL Probable translation initiation f... | 309 | 5e-53 | 181 | 36 | 53 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; IBA:RefGenome. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0003743; F:translation initiation factor activity; IBA:RefGenome. | | | | | | | | | | GO:0006446; P:regulation of translational initiation; IBA:RefGenome. | 11 | O28242 | 313 | EI2B2_ARCFU Putative translation initiation f... | 270 | 9e-31 | 122 | 30 | 48 | | | | | | | | | | | GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 12 | Q57586 | 308 | EI2B2_METJA Putative translation initiation f... | 270 | 7e-30 | 120 | 31 | 50 | | | | | | | | | | | GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 13 | O57947 | 324 | EI2B2_PYRHO Putative translation initiation f... | 267 | 9e-28 | 114 | 30 | 49 | | | | | | | | | | | GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 14 | Q9V281 | 324 | EI2B2_PYRAB Putative translation initiation f... | 277 | 2e-27 | 113 | 27 | 48 | | | | | | | | | | | GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 15 | Q8U3J1 | 276 | EI2BL_PYRFU Putative translation initiation f... | 215 | 8e-27 | 110 | 30 | 53 | | | | | | | | | | | GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 16 | Q8U4G6 | 324 | EI2B2_PYRFU Putative translation initiation f... | 280 | 2e-26 | 110 | 29 | 48 | | | | | | | | | | | GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 17 | D4GV73 | 323 | EI2B2_HALVD Putative translation initiation f... | 258 | 3e-26 | 110 | 28 | 49 | | | | | | | | | | | GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 18 | Q9UYB6 | 276 | EI2BL_PYRAB Putative translation initiation f... | 216 | 1e-23 | 101 | 30 | 50 | | | | | | | | | | | GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 19 | O58185 | 276 | EI2BL_PYRHO Putative translation initiation f... | 247 | 2e-23 | 101 | 28 | 47 | | | | | | | | | | | GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 20 | Q54EY2 | 388 | EI2BB_DICDI Translation initiation factor eIF... | 200 | 1e-21 | 97.1 | 32 | 52 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:dictyBase. | | | | | | | | | | GO:0005525; F:GTP binding; IC:dictyBase.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0003743; F:translation initiation factor activity; IBA:RefGenome. | | | | | | | | | | GO:0006446; P:regulation of translational initiation; ISS:dictyBase. | 21 | Q54FM3 | 619 | EI2BD_DICDI Translation initiation factor eIF... | 292 | 3e-21 | 97.8 | 27 | 47 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:dictyBase. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0003743; F:translation initiation factor activity; ISS:dictyBase. | | | | | | | | | | GO:0045947; P:negative regulation of translational initiation; IBA:RefGenome. | 22 | Q90511 | 355 | EI2BB_TAKRU Translation initiation factor eIF... | 227 | 1e-19 | 90.9 | 28 | 48 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:RefGenome.::GO:0003743; F:translation initiation factor activity; ISS:RefGenome. | | | | | | | | | | GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.::GO:0042552; P:myelination; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0006446; P:regulation of translational initiation; ISS:RefGenome. | 23 | A5D1G8 | 364 | MTNA_PELTS Methylthioribose-1-phosphate isome... | 288 | 2e-19 | 90.5 | 30 | 42 | | | | | | | | | | | GO:0046523; F:S-methyl-5-thioribose-1-phosphate isomerase activity; IEA:EC. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 24 | Q99LD9 | 351 | EI2BB_MOUSE Translation initiation factor eIF... | 218 | 5e-19 | 89 | 28 | 50 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0003743; F:translation initiation factor activity; IBA:RefGenome. | | | | | | | | | | GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.::GO:0042552; P:myelination; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.::GO:0006446; P:regulation of translational initiation; IBA:RefGenome. | 25 | O29877 | 339 | MTNA_ARCFU Putative methylthioribose-1-phosph... | 266 | 7e-19 | 88.6 | 27 | 46 | | | | | | | | | | | GO:0046523; F:S-methyl-5-thioribose-1-phosphate isomerase activity; IEA:EC. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 26 | P49770 | 351 | EI2BB_HUMAN Translation initiation factor eIF... | 197 | 8e-19 | 88.6 | 29 | 51 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005851; C:eukaryotic translation initiation factor 2B complex; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051716; P:cellular response to stimulus; IDA:UniProtKB.::GO:0042552; P:myelination; IMP:UniProtKB.::GO:0014003; P:oligodendrocyte development; IMP:UniProtKB.::GO:0001541; P:ovarian follicle development; IMP:UniProtKB.::GO:0006446; P:regulation of translational initiation; TAS:UniProtKB.::GO:0009749; P:response to glucose stimulus; ISS:UniProtKB.::GO:0009408; P:response to heat; ISS:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; ISS:UniProtKB. | 27 | Q5E9B4 | 351 | EI2BB_BOVIN Translation initiation factor eIF... | 197 | 1e-18 | 88.2 | 29 | 51 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:RefGenome.::GO:0003743; F:translation initiation factor activity; ISS:RefGenome. | | | | | | | | | | GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.::GO:0042552; P:myelination; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.::GO:0006446; P:regulation of translational initiation; ISS:RefGenome. | 28 | Q57896 | 329 | MTNA_METJA Putative methylthioribose-1-phosph... | 271 | 1e-18 | 87.4 | 30 | 46 | | | | | | | | | | | GO:0046523; F:S-methyl-5-thioribose-1-phosphate isomerase activity; IEA:EC. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 29 | Q62818 | 351 | EI2BB_RAT Translation initiation factor eIF-2... | 218 | 4e-18 | 86.7 | 27 | 49 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003743; F:translation initiation factor activity; IBA:RefGenome. | | | | | | | | | | GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.::GO:0042552; P:myelination; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.::GO:0006446; P:regulation of translational initiation; IBA:RefGenome.::GO:0009749; P:response to glucose stimulus; IDA:UniProtKB.::GO:0009408; P:response to heat; IDA:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; IDA:UniProtKB. | 30 | A4J678 | 346 | MTNA_DESRM Methylthioribose-1-phosphate isome... | 275 | 1e-17 | 85.1 | 28 | 47 | | | | | | | | | | | GO:0046523; F:S-methyl-5-thioribose-1-phosphate isomerase activity; IEA:EC. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 31 | B0TH58 | 345 | MTNA_HELMI Methylthioribose-1-phosphate isome... | 276 | 1e-17 | 84.7 | 31 | 44 | | | | | | | | | | | GO:0046523; F:S-methyl-5-thioribose-1-phosphate isomerase activity; IEA:EC. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. |