UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YKR019C

Length:

615

Number of sequences:

5887

Description:

YKR019C IRS4 SGDID:S000001727, Chr XI from 478063-476216, Genome Release 64-1-1, reverse complement, Verified ORF, "EH domain-containing protein involved in regulating phosphatidylinositol 4,5-bisphosphate levels and autophagy; Irs4p and Tax4p bind and activate the PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in localizing Atg17p to the PAS"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P36115	615	IRS4_YEAST Increased rDNA silencing protein 4...	615	0	1262	100	100	GO:0005739; C:mitochondrion; IDA:SGD.::GO:0000407; C:pre-autophagosomal structure; IDA:SGD.
									GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0006914; P:autophagy; IGI:SGD.::GO:0009267; P:cellular response to starvation; IGI:SGD.::GO:0000183; P:chromatin silencing at rDNA; IMP:SGD.::GO:0031505; P:fungal-type cell wall organization; IGI:SGD.::GO:0048017; P:inositol lipid-mediated signaling; IGI:SGD.::GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
2	A6ZZY3	615	IRS4_YEAS7 Increased rDNA silencing protein 4...	615	0	1259	99	99
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
3	P47030	604	TAX4_YEAST Protein TAX4 OS=Saccharomyces cere...	182	8e-60	215	56	71	GO:0000407; C:pre-autophagosomal structure; IDA:SGD.
									GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0006914; P:autophagy; IGI:SGD.::GO:0009267; P:cellular response to starvation; IGI:SGD.::GO:0031505; P:fungal-type cell wall organization; IGI:SGD.::GO:0048017; P:inositol lipid-mediated signaling; IGI:SGD.::GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
4	A6ZPP1	604	TAX4_YEAS7 Protein TAX4 OS=Saccharomyces cere...	182	9e-60	215	56	71
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
5	Q6FJW0	870	IRS4_CANGA Increased rDNA silencing protein 4...	259	1e-54	203	44	60
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
6	Q754G7	744	IRS4_ASHGO Increased rDNA silencing protein 4...	279	4e-53	198	41	54
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
7	Q6CSC2	638	IRS4_KLULA Increased rDNA silencing protein 4...	209	6e-51	191	44	62
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
8	A3LPY4	628	IRS4_PICST Increased rDNA silencing protein 4...	211	2e-34	142	36	53
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
9	Q59SR6	638	IRS4_CANAL Increased rDNA silencing protein 4...	233	2e-31	133	35	50
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0044406; P:adhesion to host; IMP:CGD.::GO:0031505; P:fungal-type cell wall organization; IMP:CGD.::GO:0030448; P:hyphal growth; IMP:CGD.::GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.::GO:0009405; P:pathogenesis; IMP:CGD.
10	Q6BRH9	765	IRS4_DEBHA Increased rDNA silencing protein 4...	181	2e-31	134	38	55
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
11	Q7SB65	856	IRS4_NEUCR Increased rDNA silencing protein 4...	136	2e-24	112	43	60
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
12	A5DBE7	667	IRS4_PICGU Increased rDNA silencing protein 4...	167	1e-23	109	34	49
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
13	A4QST9	680	IRS4_MAGO7 Increased rDNA silencing protein 4...	115	2e-23	108	47	63
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
14	Q5BH85	552	IRS4_EMENI Increased rDNA silencing protein 4...	142	3e-23	107	38	56
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
15	A1CBF3	501	IRS4_ASPCL Increased rDNA silencing protein 4...	181	1e-22	105	34	51
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
16	A5DZL0	882	IRS4_LODEL Increased rDNA silencing protein 4...	51	0.000000007	62.8	51	76
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
17	A1DDY6	513	IRS4_NEOFI Increased rDNA silencing protein 4...	137	7e-22	103	41	57
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
18	Q6C449	1005	IRS4_YARLI Increased rDNA silencing protein 4...	38	0.0000006	56.6	55	74
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
19	Q4WVH0	513	IRS4_ASPFU Increased rDNA silencing protein 4...	120	2e-20	98.6	42	61
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
20	A2RA84	504	IRS4_ASPNC Increased rDNA silencing protein 4...	197	1e-19	96.3	31	47
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
21	Q2H9M1	741	IRS4_CHAGB Increased rDNA silencing protein 4...	158	2e-19	96.7	35	46
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
22	O14066	1379	IRS4_SCHPO Increased rDNA silencing protein 4...	116	2e-19	96.7	42	55	GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005739; C:mitochondrion; ISS:PomBase.::GO:0005730; C:nucleolus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
23	A7EDF3	923	IRS4_SCLS1 Increased rDNA silencing protein 4...	124	3e-19	95.9	38	56
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
24	Q1DKE6	617	IRS4_COCIM Increased rDNA silencing protein 4...	114	1e-18	93.2	43	60
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
25	A6S9V4	885	IRS4_BOTFB Increased rDNA silencing protein 4...	122	2e-17	90.1	36	55
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
26	Q54KI4	1196	EPS15_DICDI Epidermal growth factor receptor ...	57	4.1	34.3	26	54	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.
27	P34216	1381	EDE1_YEAST EH domain-containing and endocytos...	72	0.000007	53.1	32	51	GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.
									GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IDA:SGD.
									GO:0006897; P:endocytosis; IMP:SGD.::GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:SGD.
28	Q9NZM3	1697	ITSN2_HUMAN Intersectin-2 OS=Homo sapiens (Hu...	56	0.51	37.4	36	50	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
									GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
29	Q9Z0R6	1659	ITSN2_MOUSE Intersectin-2 OS=Mus musculus (Mo...	56	0.49	37.4	36	50	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
									GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
30	Q9WVE9	1217	ITSN1_RAT Intersectin-1 OS=Rattus norvegicus ...	62	0.001	46.2	37	56	GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0006887; P:exocytosis; TAS:RGD.
31	P42566	896	EPS15_HUMAN Epidermal growth factor receptor ...	62	0.011	42.7	34	48	GO:0005829; C:cytosol; TAS:Reactome.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
									GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
									GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0048268; P:clathrin coat assembly; IDA:BHF-UCL.::GO:0032456; P:endocytic recycling; IC:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.

records

Previous

‹‹

››

Next

Total records:

86

1 - 30