Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKR019C
Length:
615
Number of sequences:
5887
Description:
YKR019C IRS4 SGDID:S000001727, Chr XI from 478063-476216, Genome Release 64-1-1, reverse complement, Verified ORF, "EH domain-containing protein involved in regulating phosphatidylinositol 4,5-bisphosphate levels and autophagy; Irs4p and Tax4p bind and activate the PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in localizing Atg17p to the PAS"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q75AA0    1203   PAN1_ASHGO Actin cytoskeleton-regulatory comp...560.018     42     34     57GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
62Q6BNL1    1449   PAN1_DEBHA Actin cytoskeleton-regulatory comp...600.037     40.8     38     52GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
63B2AWS3    1441   PAN1_PODAN Actin cytoskeleton-regulatory comp...1160.039     40.8     24     43GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
64A2R180    1434   PAN1_ASPNC Actin cytoskeleton-regulatory comp...1160.044     40.8     22     47GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
65A5DVD6    1505   PAN1_LODEL Actin cytoskeleton-regulatory comp...1190.068     40     25     44GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
66Q9EQP2    541   EHD4_MOUSE EH domain-containing protein 4 OS=...630.11     39.3     37     52GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0032456; P:endocytic recycling; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
67Q641Z6    534   EHD1_RAT EH domain-containing protein 1 OS=Ra...620.14     38.9     35     53GO:0031901; C:early endosome membrane; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0032456; P:endocytic recycling; ISS:UniProtKB.::GO:0006886; P:intracellular protein transport; ISS:UniProtKB.
68Q9WVK4    534   EHD1_MOUSE EH domain-containing protein 1 OS=...620.14     38.9     35     53GO:0031901; C:early endosome membrane; ISS:UniProtKB.::GO:0030139; C:endocytic vesicle; IDA:MGI.::GO:0005811; C:lipid particle; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0031095; C:platelet dense tubular network membrane; IDA:BHF-UCL.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.
GO:0042632; P:cholesterol homeostasis; IMP:BHF-UCL.::GO:0032456; P:endocytic recycling; ISS:UniProtKB.::GO:0006897; P:endocytosis; IDA:MGI.::GO:0006886; P:intracellular protein transport; ISS:UniProtKB.::GO:0034383; P:low-density lipoprotein particle clearance; IMP:BHF-UCL.::GO:0010886; P:positive regulation of cholesterol storage; IMP:BHF-UCL.
69Q5RBP4    534   EHD1_PONAB EH domain-containing protein 1 OS=...620.15     38.9     35     53GO:0031901; C:early endosome membrane; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0032456; P:endocytic recycling; ISS:UniProtKB.::GO:0006886; P:intracellular protein transport; ISS:UniProtKB.
70Q9H4M9    534   EHD1_HUMAN EH domain-containing protein 1 OS=...620.15     38.9     35     53GO:0031901; C:early endosome membrane; IDA:UniProtKB.::GO:0005811; C:lipid particle; ISS:BHF-UCL.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0031095; C:platelet dense tubular network membrane; ISS:BHF-UCL.::GO:0055038; C:recycling endosome membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0042632; P:cholesterol homeostasis; ISS:BHF-UCL.::GO:0032456; P:endocytic recycling; IMP:UniProtKB.::GO:0006886; P:intracellular protein transport; IMP:UniProtKB.::GO:0034383; P:low-density lipoprotein particle clearance; ISS:BHF-UCL.::GO:0010886; P:positive regulation of cholesterol storage; ISS:BHF-UCL.::GO:0051260; P:protein homooligomerization; IPI:UniProtKB.
71Q2H922    1450   PAN1_CHAGB Actin cytoskeleton-regulatory comp...550.16     38.9     36     51GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
72A7TSV7    1492   PAN1_VANPO Actin cytoskeleton-regulatory comp...600.16     38.9     35     53GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
73Q5AJ82    395   END3_CANAL Actin cytoskeleton-regulatory comp...640.21     38.1     36     52GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
74Q6FPQ7    1374   PAN1_CANGA Actin cytoskeleton-regulatory comp...600.22     38.5     32     55GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
75Q5E9R3    534   EHD1_BOVIN EH domain-containing protein 1 OS=...620.3     37.7     34     53GO:0031901; C:early endosome membrane; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0032456; P:endocytic recycling; ISS:UniProtKB.::GO:0006886; P:intracellular protein transport; ISS:UniProtKB.
76Q4V8H8    543   EHD2_RAT EH domain-containing protein 2 OS=Ra...700.3     37.7     33     47GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0032456; P:endocytic recycling; ISS:UniProtKB.
77O94685    884   UCP8_SCHPO UBA domain-containing protein 8 OS...620.3     37.7     31     53GO:0030479; C:actin cortical patch; ISS:PomBase.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0031593; F:polyubiquitin binding; TAS:PomBase.
GO:0000147; P:actin cortical patch assembly; ISS:PomBase.::GO:0006886; P:intracellular protein transport; IC:PomBase.::GO:0006898; P:receptor-mediated endocytosis; NAS:PomBase.
78Q9NZN4    543   EHD2_HUMAN EH domain-containing protein 2 OS=...700.32     37.7     33     47GO:0005634; C:nucleus; TAS:ProtInc.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0055038; C:recycling endosome membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; TAS:ProtInc.
GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0032456; P:endocytic recycling; IGI:UniProtKB.
79Q8BH64    543   EHD2_MOUSE EH domain-containing protein 2 OS=...700.35     37.7     33     47GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0019904; F:protein domain specific binding; IDA:MGI.
GO:0030866; P:cortical actin cytoskeleton organization; IDA:MGI.::GO:0032456; P:endocytic recycling; ISS:UniProtKB.::GO:0006897; P:endocytosis; IDA:MGI.
80Q5AHB1    1397   PAN1_CANAL Actin cytoskeleton-regulatory comp...590.42     37.4     32     53GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0030427; C:site of polarized growth; IDA:CGD.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IMP:CGD.::GO:0009826; P:unidimensional cell growth; IMP:CGD.
81Q9H223    541   EHD4_HUMAN EH domain-containing protein 4 OS=...630.47     37     35     52GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IDA:LIFEdb.::GO:0005634; C:nucleus; TAS:ProtInc.::GO:0055038; C:recycling endosome membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0032456; P:endocytic recycling; IGI:UniProtKB.::GO:0051260; P:protein homooligomerization; IPI:UniProtKB.
82A5DXI9    362   END3_LODEL Actin cytoskeleton-regulatory comp...580.91     35.8     34     50GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
83A3LN86    1373   PAN1_PICST Actin cytoskeleton-regulatory comp...591.1     36.2     34     51GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
84Q9SFX2    811   PUB43_ARATH U-box domain-containing protein 4...691.1     36.2     38     55GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
GO:0005488; F:binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
85A5DF78    379   END3_PICGU Actin cytoskeleton-regulatory comp...581.3     35.4     33     50GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
86Q6C370    400   END3_YARLI Actin cytoskeleton-regulatory comp...562.4     34.7     34     50GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
records
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