rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | O60260 | 465 | PRKN2_HUMAN E3 ubiquitin-protein ligase parki... | 266 | 0.00001 | 51.6 | 23 | 37 | GO:0016235; C:aggresome; IDA:BHF-UCL.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0051087; F:chaperone binding; IPI:BHF-UCL.::GO:0030165; F:PDZ domain binding; IPI:BHF-UCL.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070842; P:aggresome assembly; IMP:BHF-UCL.::GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0000422; P:mitochondrion degradation; IMP:UniProtKB.::GO:0032232; P:negative regulation of actin filament bundle assembly; IDA:BHF-UCL.::GO:0060548; P:negative regulation of cell death; IDA:BHF-UCL.::GO:0001933; P:negative regulation of protein phosphorylation; IDA:BHF-UCL.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IDA:BHF-UCL.::GO:0070997; P:neuron death; IDA:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IDA:BHF-UCL.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0006513; P:protein monoubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0010506; P:regulation of autophagy; IDA:UniProtKB.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:UniProtKB. | 62 | Q5UQ35 | 990 | YR811_MIMIV Putative ariadne-like RING finger... | 36 | 0.00002 | 51.2 | 56 | 75 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 63 | E6ZIJ1 | 707 | HOIL1_DICLA RanBP-type and C3HC4-type zinc fi... | 213 | 0.00004 | 50.1 | 24 | 39 | GO:0071797; C:LUBAC complex; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0097039; P:protein linear polyubiquitination; ISS:UniProtKB. | 64 | A9JTG5 | 714 | HOIL1_DANRE RanBP-type and C3HC4-type zinc fi... | 60 | 0.0003 | 47.4 | 32 | 53 | GO:0071797; C:LUBAC complex; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0048701; P:embryonic cranial skeleton morphogenesis; IMP:ZFIN.::GO:0071600; P:otic vesicle morphogenesis; IMP:ZFIN.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0097039; P:protein linear polyubiquitination; ISS:UniProtKB. | 65 | Q9BYM8 | 510 | HOIL1_HUMAN RanBP-type and C3HC4-type zinc fi... | 189 | 0.0003 | 47 | 24 | 40 | GO:0071797; C:LUBAC complex; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043130; F:ubiquitin binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0097039; P:protein linear polyubiquitination; IDA:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IDA:UniProtKB. | 66 | Q9US46 | 435 | ITT1_SCHPO E3 ubiquitin-protein ligase itt1 O... | 241 | 0.0005 | 46.2 | 23 | 40 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0002184; P:cytoplasmic translational termination; NAS:PomBase.::GO:0006449; P:regulation of translational termination; ISS:PomBase. | 67 | Q9WUB0 | 508 | HOIL1_MOUSE RanBP-type and C3HC4-type zinc fi... | 185 | 0.002 | 44.3 | 22 | 39 | GO:0071797; C:LUBAC complex; ISS:UniProtKB. | | | | | | | | | | GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IMP:UniProtKB.::GO:0097039; P:protein linear polyubiquitination; ISS:UniProtKB. | 68 | Q04638 | 464 | ITT1_YEAST Translation termination inhibitor ... | 264 | 0.003 | 43.9 | 23 | 38 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006449; P:regulation of translational termination; IMP:SGD. | 69 | Q4WVM1 | 1245 | RAD5_ASPFU DNA repair protein rad5 OS=A1100) ... | 80 | 0.02 | 41.6 | 25 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 70 | Q62921 | 508 | HOIL1_RAT RanBP-type and C3HC4-type zinc fing... | 48 | 0.082 | 39.3 | 31 | 60 | GO:0071797; C:LUBAC complex; ISS:UniProtKB. | | | | | | | | | | GO:0003690; F:double-stranded DNA binding; IDA:RGD.::GO:0005080; F:protein kinase C binding; IPI:RGD.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:RGD.::GO:0097039; P:protein linear polyubiquitination; ISS:UniProtKB. | 71 | P31244 | 790 | RAD16_YEAST DNA repair protein RAD16 OS=Sacch... | 101 | 0.14 | 38.9 | 27 | 48 | GO:0031463; C:Cul3-RING ubiquitin ligase complex; IDA:SGD.::GO:0000113; C:nucleotide-excision repair factor 4 complex; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000715; P:nucleotide-excision repair, DNA damage recognition; IDA:SGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:SGD. | 72 | Q7S1P9 | 1222 | RAD5_NEUCR DNA repair protein rad-5 OS=1257 /... | 102 | 0.18 | 38.5 | 25 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 73 | Q5BHD6 | 1202 | RAD5_EMENI DNA repair protein rad5 OS=194 / M... | 96 | 0.26 | 38.1 | 23 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 74 | Q9VZV5 | 412 | CYHR1_DROME Cysteine and histidine-rich prote... | 53 | 0.31 | 37.4 | 28 | 43 | | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 75 | Q5D7H7 | 547 | TRIM5_LAGLA Tripartite motif-containing prote... | 63 | 0.63 | 36.6 | 35 | 54 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 76 | Q4IJ84 | 1154 | RAD5_GIBZE DNA repair protein RAD5 OS=(Wheat ... | 123 | 0.76 | 36.6 | 24 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 77 | Q753V5 | 1085 | RAD5_ASHGO DNA repair protein RAD5 OS=Y-1056)... | 127 | 1.2 | 35.8 | 26 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 78 | Q5BN31 | 494 | TRIM5_SAIBB Tripartite motif-containing prote... | 61 | 1.5 | 35.4 | 34 | 54 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 79 | Q5D7I5 | 494 | TRIM5_CEBPY Tripartite motif-containing prote... | 63 | 1.5 | 35 | 32 | 56 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 80 | Q96EP0 | 1072 | RNF31_HUMAN E3 ubiquitin-protein ligase RNF31... | 194 | 1.6 | 35.4 | 21 | 35 | GO:0035631; C:CD40 receptor complex; ISS:BHF-UCL.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0009898; C:internal side of plasma membrane; ISS:BHF-UCL.::GO:0071797; C:LUBAC complex; IDA:UniProtKB. | | | | | | | | | | GO:0043130; F:ubiquitin binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0023035; P:CD40 signaling pathway; ISS:BHF-UCL.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0097039; P:protein linear polyubiquitination; IDA:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IDA:UniProtKB. | 81 | Q5D7I0 | 494 | TRIM5_SAISC Tripartite motif-containing prote... | 61 | 1.6 | 35 | 34 | 54 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 82 | Q5D7H8 | 494 | TRIM5_CALDO Tripartite motif-containing prote... | 63 | 1.8 | 35 | 32 | 56 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 83 | Q5D7I2 | 494 | TRIM5_PITPI Tripartite motif-containing prote... | 61 | 1.9 | 35 | 33 | 56 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 84 | Q924T7 | 1066 | RNF31_MOUSE E3 ubiquitin-protein ligase RNF31... | 85 | 2.1 | 35 | 27 | 44 | GO:0035631; C:CD40 receptor complex; IDA:BHF-UCL.::GO:0005829; C:cytosol; IDA:MGI.::GO:0009898; C:internal side of plasma membrane; IDA:BHF-UCL.::GO:0071797; C:LUBAC complex; ISS:UniProtKB. | | | | | | | | | | GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0023035; P:CD40 signaling pathway; IMP:BHF-UCL.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0097039; P:protein linear polyubiquitination; ISS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB. | 85 | Q8NHY2 | 731 | RFWD2_HUMAN E3 ubiquitin-protein ligase RFWD2... | 36 | 3.2 | 34.3 | 39 | 56 | GO:0005813; C:centrosome; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome. | 86 | Q1ACD8 | 493 | TRIM5_PANPA Tripartite motif-containing prote... | 62 | 3.2 | 34.3 | 29 | 50 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 87 | Q5D7J0 | 495 | TRIM5_COLGU Tripartite motif-containing prote... | 63 | 3.3 | 34.3 | 32 | 52 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 88 | Q5D7J1 | 493 | TRIM5_PANTR Tripartite motif-containing prote... | 62 | 3.3 | 34.3 | 29 | 50 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 89 | Q12496 | 1037 | YO098_YEAST Uncharacterized protein YOL098C O... | 74 | 3.7 | 34.3 | 34 | 53 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 90 | Q9R1A8 | 733 | RFWD2_MOUSE E3 ubiquitin-protein ligase RFWD2... | 36 | 3.8 | 34.3 | 39 | 56 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 91 | Q9C035 | 493 | TRIM5_HUMAN Tripartite motif-containing prote... | 62 | 3.8 | 33.9 | 29 | 50 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0070206; P:protein trimerization; IDA:UniProtKB.::GO:0009615; P:response to virus; IEA:UniProtKB-KW. |