Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKR017C
Length:
551
Number of sequences:
5887
Description:
YKR017C YKR017C SGDID:S000001725, Chr XI from 473349-471694, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; contains a RING finger motif"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61O60260    465   PRKN2_HUMAN E3 ubiquitin-protein ligase parki...2660.00001     51.6     23     37GO:0016235; C:aggresome; IDA:BHF-UCL.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
GO:0051087; F:chaperone binding; IPI:BHF-UCL.::GO:0030165; F:PDZ domain binding; IPI:BHF-UCL.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070842; P:aggresome assembly; IMP:BHF-UCL.::GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0000422; P:mitochondrion degradation; IMP:UniProtKB.::GO:0032232; P:negative regulation of actin filament bundle assembly; IDA:BHF-UCL.::GO:0060548; P:negative regulation of cell death; IDA:BHF-UCL.::GO:0001933; P:negative regulation of protein phosphorylation; IDA:BHF-UCL.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IDA:BHF-UCL.::GO:0070997; P:neuron death; IDA:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IDA:BHF-UCL.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0006513; P:protein monoubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0010506; P:regulation of autophagy; IDA:UniProtKB.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:UniProtKB.
62Q5UQ35    990   YR811_MIMIV Putative ariadne-like RING finger...360.00002     51.2     56     75
GO:0008270; F:zinc ion binding; IEA:InterPro.
63E6ZIJ1    707   HOIL1_DICLA RanBP-type and C3HC4-type zinc fi...2130.00004     50.1     24     39GO:0071797; C:LUBAC complex; ISS:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0097039; P:protein linear polyubiquitination; ISS:UniProtKB.
64A9JTG5    714   HOIL1_DANRE RanBP-type and C3HC4-type zinc fi...600.0003     47.4     32     53GO:0071797; C:LUBAC complex; ISS:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048701; P:embryonic cranial skeleton morphogenesis; IMP:ZFIN.::GO:0071600; P:otic vesicle morphogenesis; IMP:ZFIN.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0097039; P:protein linear polyubiquitination; ISS:UniProtKB.
65Q9BYM8    510   HOIL1_HUMAN RanBP-type and C3HC4-type zinc fi...1890.0003     47     24     40GO:0071797; C:LUBAC complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043130; F:ubiquitin binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0097039; P:protein linear polyubiquitination; IDA:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IDA:UniProtKB.
66Q9US46    435   ITT1_SCHPO E3 ubiquitin-protein ligase itt1 O...2410.0005     46.2     23     40GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0002184; P:cytoplasmic translational termination; NAS:PomBase.::GO:0006449; P:regulation of translational termination; ISS:PomBase.
67Q9WUB0    508   HOIL1_MOUSE RanBP-type and C3HC4-type zinc fi...1850.002     44.3     22     39GO:0071797; C:LUBAC complex; ISS:UniProtKB.
GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IMP:UniProtKB.::GO:0097039; P:protein linear polyubiquitination; ISS:UniProtKB.
68Q04638    464   ITT1_YEAST Translation termination inhibitor ...2640.003     43.9     23     38
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006449; P:regulation of translational termination; IMP:SGD.
69Q4WVM1    1245   RAD5_ASPFU DNA repair protein rad5 OS=A1100) ...800.02     41.6     25     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
70Q62921    508   HOIL1_RAT RanBP-type and C3HC4-type zinc fing...480.082     39.3     31     60GO:0071797; C:LUBAC complex; ISS:UniProtKB.
GO:0003690; F:double-stranded DNA binding; IDA:RGD.::GO:0005080; F:protein kinase C binding; IPI:RGD.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:RGD.::GO:0097039; P:protein linear polyubiquitination; ISS:UniProtKB.
71P31244    790   RAD16_YEAST DNA repair protein RAD16 OS=Sacch...1010.14     38.9     27     48GO:0031463; C:Cul3-RING ubiquitin ligase complex; IDA:SGD.::GO:0000113; C:nucleotide-excision repair factor 4 complex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000715; P:nucleotide-excision repair, DNA damage recognition; IDA:SGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:SGD.
72Q7S1P9    1222   RAD5_NEUCR DNA repair protein rad-5 OS=1257 /...1020.18     38.5     25     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
73Q5BHD6    1202   RAD5_EMENI DNA repair protein rad5 OS=194 / M...960.26     38.1     23     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
74Q9VZV5    412   CYHR1_DROME Cysteine and histidine-rich prote...530.31     37.4     28     43
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
75Q5D7H7    547   TRIM5_LAGLA Tripartite motif-containing prote...630.63     36.6     35     54GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
76Q4IJ84    1154   RAD5_GIBZE DNA repair protein RAD5 OS=(Wheat ...1230.76     36.6     24     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
77Q753V5    1085   RAD5_ASHGO DNA repair protein RAD5 OS=Y-1056)...1271.2     35.8     26     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
78Q5BN31    494   TRIM5_SAIBB Tripartite motif-containing prote...611.5     35.4     34     54GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
79Q5D7I5    494   TRIM5_CEBPY Tripartite motif-containing prote...631.5     35     32     56GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
80Q96EP0    1072   RNF31_HUMAN E3 ubiquitin-protein ligase RNF31...1941.6     35.4     21     35GO:0035631; C:CD40 receptor complex; ISS:BHF-UCL.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0009898; C:internal side of plasma membrane; ISS:BHF-UCL.::GO:0071797; C:LUBAC complex; IDA:UniProtKB.
GO:0043130; F:ubiquitin binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0023035; P:CD40 signaling pathway; ISS:BHF-UCL.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0097039; P:protein linear polyubiquitination; IDA:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IDA:UniProtKB.
81Q5D7I0    494   TRIM5_SAISC Tripartite motif-containing prote...611.6     35     34     54GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
82Q5D7H8    494   TRIM5_CALDO Tripartite motif-containing prote...631.8     35     32     56GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
83Q5D7I2    494   TRIM5_PITPI Tripartite motif-containing prote...611.9     35     33     56GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
84Q924T7    1066   RNF31_MOUSE E3 ubiquitin-protein ligase RNF31...852.1     35     27     44GO:0035631; C:CD40 receptor complex; IDA:BHF-UCL.::GO:0005829; C:cytosol; IDA:MGI.::GO:0009898; C:internal side of plasma membrane; IDA:BHF-UCL.::GO:0071797; C:LUBAC complex; ISS:UniProtKB.
GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0023035; P:CD40 signaling pathway; IMP:BHF-UCL.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0097039; P:protein linear polyubiquitination; ISS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.
85Q8NHY2    731   RFWD2_HUMAN E3 ubiquitin-protein ligase RFWD2...363.2     34.3     39     56GO:0005813; C:centrosome; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
86Q1ACD8    493   TRIM5_PANPA Tripartite motif-containing prote...623.2     34.3     29     50GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
87Q5D7J0    495   TRIM5_COLGU Tripartite motif-containing prote...633.3     34.3     32     52GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
88Q5D7J1    493   TRIM5_PANTR Tripartite motif-containing prote...623.3     34.3     29     50GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
89Q12496    1037   YO098_YEAST Uncharacterized protein YOL098C O...743.7     34.3     34     53GO:0005737; C:cytoplasm; IDA:SGD.
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
90Q9R1A8    733   RFWD2_MOUSE E3 ubiquitin-protein ligase RFWD2...363.8     34.3     39     56GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
91Q9C035    493   TRIM5_HUMAN Tripartite motif-containing prote...623.8     33.9     29     50GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0070206; P:protein trimerization; IDA:UniProtKB.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.
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