UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YKR014C

Length:

234

Number of sequences:

5887

Description:

YKR014C YPT52 SGDID:S000001722, Chr XI from 466071-465367, Genome Release 64-1-1, reverse complement, Verified ORF, "Rab family GTPase, similar to Ypt51p and Ypt53p and to mammalian rab5; required for vacuolar protein sorting and endocytosis"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P36018	234	YPT52_YEAST GTP-binding protein YPT52 OS=Sacc...	234	1e-172	481	100	100	GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005770; C:late endosome; IMP:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0006897; P:endocytosis; IMP:SGD.::GO:0006623; P:protein targeting to vacuole; IMP:SGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
2	P36017	210	VPS21_YEAST Vacuolar protein sorting-associat...	229	7e-61	196	48	64	GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005770; C:late endosome; IMP:SGD.::GO:0005741; C:mitochondrial outer membrane; IDA:SGD.
									GO:0005525; F:GTP binding; IDA:SGD.::GO:0003924; F:GTPase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0006897; P:endocytosis; IMP:SGD.::GO:0006623; P:protein targeting to vacuole; IMP:SGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0000011; P:vacuole inheritance; IMP:SGD.
3	Q58DS9	216	RAB5C_BOVIN Ras-related protein Rab-5C OS=Bos...	234	1e-59	193	47	60	GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
4	Q5R7L7	216	RAB5C_PONAB Ras-related protein Rab-5C OS=Pon...	234	4e-59	192	47	59	GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
5	P51148	216	RAB5C_HUMAN Ras-related protein Rab-5C OS=Hom...	234	4e-59	192	47	59	GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005811; C:lipid particle; IDA:UniProtKB.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
6	P36586	211	YPT5_SCHPO GTP-binding protein ypt5 OS=Schizo...	230	1e-58	190	50	63	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005770; C:late endosome; ISS:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IDA:PomBase.::GO:0003924; F:GTPase activity; ISS:PomBase.
									GO:0006897; P:endocytosis; ISS:PomBase.::GO:0070314; P:G1 to G0 transition; IMP:PomBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0033157; P:regulation of intracellular protein transport; IC:PomBase.::GO:0031338; P:regulation of vesicle fusion; IMP:PomBase.::GO:0007264; P:small GTPase mediated signal transduction; IC:PomBase.
7	Q98932	216	RAB5C_CHICK Ras-related protein Rab-5C OS=Gal...	234	2e-58	191	48	59	GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
8	P61271	215	RAB5A_MACFA Ras-related protein Rab-5A OS=Mac...	235	2e-58	190	46	59	GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006897; P:endocytosis; ISS:UniProtKB.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
9	P18066	215	RAB5A_CANFA Ras-related protein Rab-5A OS=Can...	235	2e-58	190	46	59	GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005811; C:lipid particle; IDA:UniProtKB.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
10	Q9CQD1	215	RAB5A_MOUSE Ras-related protein Rab-5A OS=Mus...	235	2e-58	190	46	59	GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0030139; C:endocytic vesicle; IDA:MGI.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0001726; C:ruffle; IDA:MGI.
									GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:MGI.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
11	P35278	216	RAB5C_MOUSE Ras-related protein Rab-5C OS=Mus...	234	3e-58	190	47	59	GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0030139; C:endocytic vesicle; IDA:MGI.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:MGI.::GO:0005515; F:protein binding; IPI:MGI.
									GO:0007032; P:endosome organization; IDA:MGI.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0030100; P:regulation of endocytosis; IDA:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
12	Q0IIG7	215	RAB5A_BOVIN Ras-related protein Rab-5A OS=Bos...	235	3e-58	190	46	59	GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006897; P:endocytosis; ISS:UniProtKB.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
13	P20339	215	RAB5A_HUMAN Ras-related protein Rab-5A OS=Hom...	235	3e-58	190	46	58	GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0019003; F:GDP binding; IDA:UniProtKB.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0045921; P:positive regulation of exocytosis; IMP:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:2000286; P:receptor internalization involved in canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0051489; P:regulation of filopodium assembly; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
14	P51147	216	RAB5C_CANFA Ras-related protein Rab-5C OS=Can...	234	3e-58	190	47	59	GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
15	Q06AU6	215	RAB5A_PIG Ras-related protein Rab-5A OS=Sus s...	234	4e-58	189	47	59	GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006897; P:endocytosis; ISS:UniProtKB.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
16	Q86JP3	201	RAB5A_DICDI Ras-related protein Rab-5A OS=Dic...	193	5e-57	186	50	66	GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
17	P36019	220	YPT53_YEAST GTP-binding protein YPT53 OS=Sacc...	192	8e-57	186	53	66	GO:0005770; C:late endosome; IMP:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0006897; P:endocytosis; IMP:SGD.::GO:0006623; P:protein targeting to vacuole; IMP:SGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
18	Q5RBG1	215	RAB5B_PONAB Ras-related protein Rab-5B OS=Pon...	234	3e-56	184	45	58	GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
19	P61021	215	RAB5B_MOUSE Ras-related protein Rab-5B OS=Mus...	234	3e-56	184	45	58	GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0030139; C:endocytic vesicle; IDA:MGI.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:MGI.
									GO:0007032; P:endosome organization; IDA:MGI.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0030100; P:regulation of endocytosis; IDA:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
20	P61020	215	RAB5B_HUMAN Ras-related protein Rab-5B OS=Hom...	234	3e-56	184	45	58	GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0005886; C:plasma membrane; TAS:ProtInc.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0030742; F:GTP-dependent protein binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; TAS:ProtInc.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
21	Q5ZHW4	215	RAB5B_CHICK Ras-related protein Rab-5B OS=Gal...	234	5e-55	181	45	59	GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
22	Q9SN68	200	RAF2B_ARATH Ras-related protein RABF2b OS=Ara...	196	6e-55	181	48	63	GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
23	P31582	200	RAF2A_ARATH Ras-related protein RABF2a OS=Ara...	196	9e-55	180	48	63	GO:0005774; C:vacuolar membrane; IMP:UniProtKB.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0007034; P:vacuolar transport; IMP:UniProtKB.
24	P29687	200	RAB5_TOBAC Ras-related protein Rab5 OS=Nicoti...	192	3e-53	176	49	64	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
25	P31583	200	RHN1_NICPL Ras-related protein RHN1 OS=Nicoti...	192	8e-53	175	48	61	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
26	Q9CB01	202	RABF1_ARATH Ras-related protein RABF1 OS=Arab...	192	2e-49	167	45	63	GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0010009; C:external side of endosome membrane; IDA:TAIR.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0045022; P:early endosome to late endosome transport; IMP:TAIR.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
27	Q13636	194	RAB31_HUMAN Ras-related protein Rab-31 OS=Hom...	231	6e-46	157	39	55	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.
									GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
28	Q6GQP4	194	RAB31_RAT Ras-related protein Rab-31 OS=Rattu...	231	7e-44	152	39	55	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0048193; P:Golgi vesicle transport; IMP:RGD.::GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
29	Q921E2	194	RAB31_MOUSE Ras-related protein Rab-31 OS=Mus...	231	1e-43	151	39	55	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
30	P61294	208	RAB6B_MOUSE Ras-related protein Rab-6B OS=Mus...	222	3e-42	148	36	58	GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
31	Q9NRW1	208	RAB6B_HUMAN Ras-related protein Rab-6B OS=Hom...	222	3e-42	148	36	58	GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; NAS:UniProtKB.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; NAS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.

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