Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKR014C
Length:
234
Number of sequences:
5887
Description:
YKR014C YPT52 SGDID:S000001722, Chr XI from 466071-465367, Genome Release 64-1-1, reverse complement, Verified ORF, "Rab family GTPase, similar to Ypt51p and Ypt53p and to mammalian rab5; required for vacuolar protein sorting and endocytosis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
961Q9GPS0    201   RACG_DICDI Rho-related protein racG OS=Dictyo...1920.0003     44.3     21     43GO:0005938; C:cell cortex; IDA:dictyBase.::GO:0032009; C:early phagosome; IDA:dictyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0006928; P:cellular component movement; IMP:dictyBase.::GO:0046847; P:filopodium assembly; IMP:dictyBase.::GO:0006909; P:phagocytosis; IDA:dictyBase.::GO:0030838; P:positive regulation of actin filament polymerization; IDA:dictyBase.::GO:0032314; P:regulation of Rac GTPase activity; IMP:dictyBase.::GO:0019953; P:sexual reproduction; IEP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
962P91924    183   ARF_DUGJA ADP-ribosylation factor OS=Dugesia ...1330.0003     43.9     23     47GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
963Q0VC18    200   ARL4D_BOVIN ADP-ribosylation factor-like prot...1250.0003     43.9     26     49GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
964Q80ZU0    179   ARL5A_MOUSE ADP-ribosylation factor-like prot...1330.0003     43.5     23     48GO:0005622; C:intracellular; IEA:InterPro.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
965Q6FUZ9    189   SAR1_CANGA Small COPII coat GTPase SAR1 OS=NR...1330.0004     43.9     26     40GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
966Q9Y272    281   RASD1_HUMAN Dexamethasone-induced Ras-related...1330.0004     44.3     26     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.
GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
967O35626    280   RASD1_MOUSE Dexamethasone-induced Ras-related...1330.0004     44.3     25     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
968Q5ZM83    618   MIRO2_CHICK Mitochondrial Rho GTPase 2 OS=Gal...1320.0004     44.7     29     48GO:0031307; C:integral to mitochondrial outer membrane; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0019725; P:cellular homeostasis; ISS:UniProtKB.::GO:0047497; P:mitochondrion transport along microtubule; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
969Q4PB75    752   GEM1_USTMA Mitochondrial Rho GTPase 1 OS=Usti...1250.0004     44.7     29     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
970Q19705    184   ARL2_CAEEL ADP-ribosylation factor-like prote...1330.0005     43.5     25     47GO:0005818; C:aster; IDA:WormBase.::GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0043622; P:cortical microtubule organization; IMP:WormBase.::GO:0000910; P:cytokinesis; IMP:UniProtKB.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0030540; P:female genitalia development; IMP:UniProtKB.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
971P97538    208   RASM_RAT Ras-related protein M-Ras OS=Rattus ...1880.0005     43.5     25     46GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
972Q8IXI1    618   MIRO2_HUMAN Mitochondrial Rho GTPase 2 OS=Hom...1340.0005     44.3     28     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0031307; C:integral to mitochondrial outer membrane; IDA:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IMP:UniProtKB.::GO:0019725; P:cellular homeostasis; IMP:UniProtKB.::GO:0047497; P:mitochondrion transport along microtubule; IMP:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
973P49702    180   ARF5_CHICK ADP-ribosylation factor 5 OS=Gallu...1330.0005     43.1     23     47GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:AgBase.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
974O08989    208   RASM_MOUSE Ras-related protein M-Ras OS=Mus m...1880.0005     43.5     25     46GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
975Q9JKF8    280   RASD1_RAT Dexamethasone-induced Ras-related p...1330.0005     43.9     25     50GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0007263; P:nitric oxide mediated signal transduction; IDA:RGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
976Q6P068    179   ARL5C_MOUSE ADP-ribosylation factor-like prot...1430.0007     42.7     22     45GO:0005622; C:intracellular; IEA:InterPro.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
977Q8CEC5    192   KBRS1_MOUSE NF-kappa-B inhibitor-interacting ...1920.0007     43.1     22     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
978P25160    180   ARL1_DROME ADP-ribosylation factor-like prote...1330.0008     42.7     23     46GO:0005794; C:Golgi apparatus; IDA:FlyBase.
GO:0005525; F:GTP binding; IDA:FlyBase.
GO:0033227; P:dsRNA transport; IMP:FlyBase.::GO:0090158; P:endoplasmic reticulum membrane organization; IMP:FlyBase.::GO:0016197; P:endosome transport; TAS:FlyBase.::GO:0007030; P:Golgi organization; IMP:FlyBase.::GO:0007269; P:neurotransmitter secretion; TAS:FlyBase.::GO:0030334; P:regulation of cell migration; IMP:FlyBase.::GO:0060628; P:regulation of ER to Golgi vesicle-mediated transport; IMP:FlyBase.::GO:0070861; P:regulation of protein exit from endoplasmic reticulum; IMP:FlyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0048488; P:synaptic vesicle endocytosis; TAS:FlyBase.
979Q2YDM1    181   ARL1_BOVIN ADP-ribosylation factor-like prote...1400.0008     42.7     24     46GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005802; C:trans-Golgi network; ISS:UniProtKB.
GO:0008047; F:enzyme activator activity; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0031584; P:activation of phospholipase D activity; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0034067; P:protein localization in Golgi apparatus; ISS:UniProtKB.::GO:0042147; P:retrograde transport, endosome to Golgi; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0009404; P:toxin metabolic process; ISS:UniProtKB.
980Q6DGN0    205   RERGL_DANRE Ras-related and estrogen-regulate...1820.0008     42.7     27     40GO:0016020; C:membrane; IEA:InterPro.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
981P36579    180   ARF1_SCHPO ADP-ribosylation factor 1 OS=Schiz...1430.0008     42.7     21     45GO:0005794; C:Golgi apparatus; IDA:PomBase.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; ISS:PomBase.
GO:0006888; P:ER to Golgi vesicle-mediated transport; ISS:PomBase.::GO:0006886; P:intracellular protein transport; IC:PomBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
982P61212    181   ARL1_RAT ADP-ribosylation factor-like protein...1400.0008     42.7     24     46GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005802; C:trans-Golgi network; IDA:RGD.
GO:0008047; F:enzyme activator activity; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0031584; P:activation of phospholipase D activity; ISS:UniProtKB.::GO:0007030; P:Golgi organization; IMP:RGD.::GO:0048193; P:Golgi vesicle transport; IMP:RGD.::GO:0034067; P:protein localization in Golgi apparatus; ISS:UniProtKB.::GO:0042147; P:retrograde transport, endosome to Golgi; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0009404; P:toxin metabolic process; ISS:UniProtKB.
983P61211    181   ARL1_MOUSE ADP-ribosylation factor-like prote...1400.0008     42.7     24     46GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005802; C:trans-Golgi network; ISS:UniProtKB.
GO:0008047; F:enzyme activator activity; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0031584; P:activation of phospholipase D activity; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0034067; P:protein localization in Golgi apparatus; ISS:UniProtKB.::GO:0042147; P:retrograde transport, endosome to Golgi; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0009404; P:toxin metabolic process; ISS:UniProtKB.
984Q55AD9    183   ARL5_DICDI ADP-ribosylation factor-like prote...1430.0009     42.4     24     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
985Q5S007    2527   LRRK2_HUMAN Leucine-rich repeat serine/threon...1330.001     43.9     23     50GO:0032473; C:external side of mitochondrial outer membrane; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0043005; C:neuron projection; IDA:BHF-UCL.::GO:0043025; C:neuronal cell body; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0034211; F:GTP-dependent protein kinase activity; IMP:UniProtKB.::GO:0005096; F:GTPase activator activity; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:BHF-UCL.::GO:0004708; F:MAP kinase kinase activity; IDA:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0017048; F:Rho GTPase binding; IPI:BHF-UCL.::GO:0015631; F:tubulin binding; IDA:BHF-UCL.
GO:0000186; P:activation of MAPKK activity; IDA:BHF-UCL.::GO:0008340; P:determination of adult lifespan; IMP:BHF-UCL.::GO:0035640; P:exploration behavior; IMP:BHF-UCL.::GO:0048312; P:intracellular distribution of mitochondria; IMP:BHF-UCL.::GO:2000173; P:negative regulation of branching morphogenesis of a nerve; IMP:BHF-UCL.::GO:0061002; P:negative regulation of dendritic spine morphogenesis; IMP:BHF-UCL.::GO:0007406; P:negative regulation of neuroblast proliferation; IMP:BHF-UCL.::GO:0014043; P:negative regulation of neuron maturation; IMP:BHF-UCL.::GO:0007528; P:neuromuscular junction development; IMP:BHF-UCL.::GO:0070997; P:neuron death; IMP:BHF-UCL.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.::GO:0010508; P:positive regulation of autophagy; ISS:BHF-UCL.::GO:0060161; P:positive regulation of dopamine receptor signaling pathway; IMP:BHF-UCL.::GO:0043068; P:positive regulation of programmed cell death; IDA:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:BHF-UCL.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0035564; P:regulation of kidney size; ISS:BHF-UCL.::GO:0040012; P:regulation of locomotion; IMP:BHF-UCL.::GO:0042391; P:regulation of membrane potential; IMP:BHF-UCL.::GO:0006979; P:response to oxidative stress; IMP:BHF-UCL.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0022028; P:tangential migration from the subventricular zone to the olfactory bulb; IMP:BHF-UCL.
986Q5E9M9    618   MIRO2_BOVIN Mitochondrial Rho GTPase 2 OS=Bos...1910.001     43.5     26     43GO:0031307; C:integral to mitochondrial outer membrane; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0019725; P:cellular homeostasis; ISS:UniProtKB.::GO:0047497; P:mitochondrion transport along microtubule; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
987P61751    180   ARF4_RAT ADP-ribosylation factor 4 OS=Rattus ...1400.001     42.4     21     44GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007420; P:brain development; IEP:RGD.::GO:0007173; P:epidermal growth factor receptor signaling pathway; IDA:RGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0048678; P:response to axon injury; IEP:RGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
988P61750    180   ARF4_MOUSE ADP-ribosylation factor 4 OS=Mus m...1400.001     42.4     21     44GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0005525; F:GTP binding; TAS:MGI.
GO:0015031; P:protein transport; TAS:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
989P20606    190   SAR1_YEAST Small COPII coat GTPase SAR1 OS=Sa...1240.001     42.4     27     42GO:0030127; C:COPII vesicle coat; IDA:SGD.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:SGD.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0003400; P:regulation of COPII vesicle coating; IDA:SGD.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
990Q8VEL9    341   REM2_MOUSE GTP-binding protein REM 2 OS=Mus m...1840.001     43.1     22     39GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0008134; F:transcription factor binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
991Q6NVC5    619   MIRO1_DANRE Mitochondrial Rho GTPase 1-A OS=D...2200.001     43.1     24     43GO:0031307; C:integral to mitochondrial outer membrane; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0019725; P:cellular homeostasis; ISS:UniProtKB.::GO:0047497; P:mitochondrion transport along microtubule; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
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