Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKR014C
Length:
234
Number of sequences:
5887
Description:
YKR014C YPT52 SGDID:S000001722, Chr XI from 466071-465367, Genome Release 64-1-1, reverse complement, Verified ORF, "Rab family GTPase, similar to Ypt51p and Ypt53p and to mammalian rab5; required for vacuolar protein sorting and endocytosis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
751P22981    184   LET60_CAEEL Ras protein let-60 OS=Caenorhabdi...1860.000000004     57.4     28     47GO:0005938; C:cell cortex; IDA:WormBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0007517; P:muscle organ development; IMP:WormBase.::GO:0048477; P:oogenesis; IGI:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0042659; P:regulation of cell fate specification; IMP:WormBase.::GO:0031344; P:regulation of cell projection organization; IMP:WormBase.::GO:0032940; P:secretion by cell; IMP:WormBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0040025; P:vulval development; IMP:WormBase.
752Q9EQT3    261   RHOU_MOUSE Rho-related GTP-binding protein Rh...1960.000000004     58.5     26     43GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0002102; C:podosome; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IMP:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0030036; P:actin cytoskeleton organization; IDA:MGI.::GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:MGI.::GO:0016601; P:Rac protein signal transduction; IDA:MGI.::GO:0008360; P:regulation of cell shape; IDA:MGI.
753P26990    175   ARF6_CHICK ADP-ribosylation factor 6 OS=Gallu...1850.000000005     57     23     42GO:0005938; C:cell cortex; ISS:AgBase.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0031527; C:filopodium membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; ISS:AgBase.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030866; P:cortical actin cytoskeleton organization; ISS:AgBase.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0030838; P:positive regulation of actin filament polymerization; ISS:AgBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0035020; P:regulation of Rac protein signal transduction; ISS:AgBase.::GO:0031529; P:ruffle organization; ISS:AgBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
754Q7L0Q8    258   RHOU_HUMAN Rho-related GTP-binding protein Rh...1960.000000005     58.2     26     43GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0002102; C:podosome; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
755O93856    209   RAS_LACBI Ras-like protein OS=bicolor). GN= ...1890.000000006     57.4     26     44GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
756C4YDI6    191   CDC42_CANAW Cell division control protein 42 ...1880.000000006     57.4     24     45GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
757P0CY33    191   CDC42_CANAL Cell division control protein 42 ...1880.000000006     57.4     24     45GO:0030428; C:cell septum; NAS:CGD.::GO:0005935; C:cellular bud neck; IDA:CGD.::GO:0005934; C:cellular bud tip; IDA:CGD.::GO:0031562; C:hyphal tip polarisome; IDA:CGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0031521; C:spitzenkorper; IDA:CGD.
GO:0005525; F:GTP binding; IDA:CGD.
GO:0007114; P:cell budding; IMP:CGD.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000920; P:cytokinetic cell separation; IMP:CGD.::GO:0030010; P:establishment of cell polarity; IMP:CGD.::GO:0030448; P:hyphal growth; IMP:CGD.::GO:0009405; P:pathogenesis; IMP:CGD.::GO:0001558; P:regulation of cell growth; IMP:CGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
758Q54BW4    3933   CPAS2_DICDI Circularly permutated Ras protein...396.3     32     36     64GO:0016020; C:membrane; IEA:InterPro.
GO:0004866; F:endopeptidase inhibitor activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
759P32252    197   RASB_DICDI Ras-like protein rasB OS=Dictyoste...2090.000000007     57     28     47GO:0016363; C:nuclear matrix; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; ISS:dictyBase.::GO:0003924; F:GTPase activity; ISS:dictyBase.::GO:0005515; F:protein binding; IPI:dictyBase.
GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0045806; P:negative regulation of endocytosis; IMP:dictyBase.::GO:0007265; P:Ras protein signal transduction; ISS:dictyBase.::GO:0051726; P:regulation of cell cycle; IEP:dictyBase.::GO:0042127; P:regulation of cell proliferation; IMP:dictyBase.::GO:0051270; P:regulation of cellular component movement; IGI:dictyBase.
760P48559    417   YPT11_YEAST GTP-binding protein YPT11 OS=Sacc...790.000000008     58.5     38     56GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000131; C:incipient cellular bud site; IDA:SGD.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IPI:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0048309; P:endoplasmic reticulum inheritance; IMP:SGD.::GO:0048313; P:Golgi inheritance; IGI:SGD.::GO:0051645; P:Golgi localization; IMP:SGD.::GO:0000001; P:mitochondrion inheritance; IMP:SGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
761A6ZSH6    417   YPT11_YEAS7 GTP-binding protein YPT11 OS=Sacc...790.000000008     58.5     38     56GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0005934; C:cellular bud tip; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
762B5VQB6    417   YPT11_YEAS6 GTP-binding protein YPT11 OS=Sacc...790.000000008     58.5     38     56GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0005934; C:cellular bud tip; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
763O82481    215   RAC10_ARATH Rac-like GTP-binding protein ARAC...1870.000000008     57.4     25     44GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
764B3LPD8    417   YPT11_YEAS1 GTP-binding protein YPT11 OS=Sacc...790.000000008     58.5     38     56GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0005934; C:cellular bud tip; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
765Q12526    212   RAS_EMENI Ras-like protein OS=194 / M139) (As...1890.000000008     57     26     44GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
766P40946    175   ARF3_DROME ADP-ribosylation factor 3 OS=Droso...1850.000000009     56.2     23     42GO:0005829; C:cytosol; IDA:FlyBase.::GO:0005769; C:early endosome; IDA:FlyBase.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:FlyBase.::GO:0055037; C:recycling endosome; IDA:FlyBase.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003956; F:NAD(P)+-protein-arginine ADP-ribosyltransferase activity; IDA:FlyBase.
GO:0030036; P:actin cytoskeleton organization; IMP:FlyBase.::GO:0016197; P:endosome transport; TAS:FlyBase.::GO:0007112; P:male meiosis cytokinesis; IMP:FlyBase.::GO:0007520; P:myoblast fusion; IMP:FlyBase.::GO:0007269; P:neurotransmitter secretion; NAS:FlyBase.::GO:0006471; P:protein ADP-ribosylation; IDA:FlyBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0007283; P:spermatogenesis; IMP:FlyBase.::GO:0048488; P:synaptic vesicle endocytosis; TAS:FlyBase.
767B4JFU8    189   RAS1_DROGR Ras-like protein 1 OS=Drosophila g...1860.000000009     56.6     26     48GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
768Q55G45    658   GEMA_DICDI Probable mitochondrial Rho GTPase ...1860.00000001     58.5     26     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; ISS:dictyBase.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; ISS:dictyBase.
GO:0019725; P:cellular homeostasis; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
769B4NJ72    189   RAS1_DROWI Ras-like protein 1 OS=Drosophila w...1860.00000001     56.6     26     48GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
770Q54RY4    233   RABV_DICDI Ras-related protein RabV OS=Dictyo...1260.00000001     57.4     29     47
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
771Q24816    194   RACC_ENTHI Rho-related protein racC OS=Entamo...1870.00000001     56.6     26     47GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
772P34146    193   RAC1C_DICDI Rho-related protein rac1C OS=Dict...1900.00000001     56.6     24     45GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:dictyBase.
GO:0019953; P:sexual reproduction; IEP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
773P55041    295   GEM_MOUSE GTP-binding protein GEM OS=Mus musc...2450.00000001     57.8     24     42GO:0005634; C:nucleus; IDA:MGI.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
774Q9P8J9    206   RHO3_SCHCO GTP-binding protein Rho3 OS=Schizo...1940.00000001     56.6     24     45GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
775P15064    189   RASG_DICDI Ras-like protein rasG OS=Dictyoste...2000.00000001     56.2     27     46GO:0045335; C:phagocytic vesicle; IDA:dictyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IDA:dictyBase.::GO:0003924; F:GTPase activity; IDA:dictyBase.::GO:0005515; F:protein binding; IPI:dictyBase.
GO:0007190; P:activation of adenylate cyclase activity; IGI:dictyBase.::GO:0032861; P:activation of Rap GTPase activity; IMP:dictyBase.::GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0000902; P:cell morphogenesis; IMP:dictyBase.::GO:0008283; P:cell proliferation; IGI:dictyBase.::GO:0031589; P:cell-substrate adhesion; IMP:dictyBase.::GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0007188; P:G-protein signaling, coupled to cAMP nucleotide second messenger; IMP:dictyBase.::GO:0008284; P:positive regulation of cell proliferation; IMP:dictyBase.::GO:0030828; P:positive regulation of cGMP biosynthetic process; IMP:dictyBase.::GO:0031284; P:positive regulation of guanylate cyclase activity; IMP:dictyBase.::GO:0050927; P:positive regulation of positive chemotaxis; IMP:dictyBase.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:dictyBase.::GO:0007265; P:Ras protein signal transduction; IDA:dictyBase.::GO:0046586; P:regulation of calcium-dependent cell-cell adhesion; IMP:dictyBase.::GO:0001932; P:regulation of protein phosphorylation; IMP:dictyBase.
776Q7YS69    181   REBL1_BOVIN GTPase RhebL1 OS=Bos taurus (Bovi...1750.00000001     55.8     26     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
777Q6Z808    214   RAC3_ORYSJ Rac-like GTP-binding protein 3 OS=...1840.00000002     56.2     23     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
778P62332    175   ARF6_RAT ADP-ribosylation factor 6 OS=Rattus ...1850.00000002     55.8     23     42GO:0005769; C:early endosome; IDA:RGD.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0031527; C:filopodium membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IDA:RGD.::GO:0001726; C:ruffle; IDA:RGD.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0016358; P:dendrite development; TAS:RGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0060998; P:regulation of dendritic spine development; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
779Q007T5    175   ARF6_PIG ADP-ribosylation factor 6 OS=Sus scr...1850.00000002     55.8     23     42GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0031527; C:filopodium membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0060998; P:regulation of dendritic spine development; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
780P62331    175   ARF6_MOUSE ADP-ribosylation factor 6 OS=Mus m...1850.00000002     55.8     23     42GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0031527; C:filopodium membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; TAS:BHF-UCL.::GO:0003924; F:GTPase activity; TAS:BHF-UCL.
GO:0006915; P:apoptotic process; IMP:MGI.::GO:0090162; P:establishment of epithelial cell polarity; IMP:MGI.::GO:0001889; P:liver development; IMP:MGI.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IDA:BHF-UCL.::GO:0034394; P:protein localization at cell surface; IDA:BHF-UCL.::GO:0015031; P:protein transport; TAS:MGI.::GO:0060998; P:regulation of dendritic spine development; IMP:UniProtKB.::GO:0034143; P:regulation of toll-like receptor 4 signaling pathway; NAS:BHF-UCL.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
781P62330    175   ARF6_HUMAN ADP-ribosylation factor 6 OS=Homo ...1850.00000002     55.8     23     42GO:0005938; C:cell cortex; IDA:UniProtKB.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0031527; C:filopodium membrane; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0001726; C:ruffle; IDA:UniProtKB.
GO:0005525; F:GTP binding; TAS:UniProtKB.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0031996; F:thioesterase binding; IPI:UniProtKB.
GO:0007155; P:cell adhesion; TAS:UniProtKB.::GO:0006928; P:cellular component movement; TAS:UniProtKB.::GO:0030866; P:cortical actin cytoskeleton organization; IMP:UniProtKB.::GO:0048261; P:negative regulation of receptor-mediated endocytosis; TAS:UniProtKB.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:UniProtKB.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; ISS:BHF-UCL.::GO:0034394; P:protein localization at cell surface; ISS:BHF-UCL.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0060998; P:regulation of dendritic spine development; ISS:UniProtKB.::GO:0051489; P:regulation of filopodium assembly; IDA:UniProtKB.::GO:0035020; P:regulation of Rac protein signal transduction; IDA:UniProtKB.::GO:0031529; P:ruffle organization; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; TAS:UniProtKB.
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