Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKR014C
Length:
234
Number of sequences:
5887
Description:
YKR014C YPT52 SGDID:S000001722, Chr XI from 466071-465367, Genome Release 64-1-1, reverse complement, Verified ORF, "Rab family GTPase, similar to Ypt51p and Ypt53p and to mammalian rab5; required for vacuolar protein sorting and endocytosis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
661O04369    197   RAC1_LOTJA Rac-like GTP-binding protein RAC1 ...1840.00000000003     63.5     27     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
662Q68Y52    214   RAC2_ORYSJ Rac-like GTP-binding protein 2 OS=...1850.00000000003     63.9     26     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
663Q8BU31    183   RAP2C_MOUSE Ras-related protein Rap-2c OS=Mus...1930.00000000003     63.2     29     47GO:0005829; C:cytosol; IDA:MGI.::GO:0055038; C:recycling endosome membrane; IDA:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0030336; P:negative regulation of cell migration; IDA:MGI.::GO:0031954; P:positive regulation of protein autophosphorylation; IDA:MGI.::GO:0032486; P:Rap protein signal transduction; IDA:UniProtKB.::GO:0061097; P:regulation of protein tyrosine kinase activity; IDA:UniProtKB.
664Q9Y3L5    183   RAP2C_HUMAN Ras-related protein Rap-2c OS=Hom...1930.00000000003     63.2     29     47GO:0055038; C:recycling endosome membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0031954; P:positive regulation of protein autophosphorylation; ISS:UniProtKB.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.::GO:0061097; P:regulation of protein tyrosine kinase activity; ISS:UniProtKB.
665Q08DI5    183   RAP2C_BOVIN Ras-related protein Rap-2c OS=Bos...1930.00000000003     63.2     29     47GO:0055038; C:recycling endosome membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0031954; P:positive regulation of protein autophosphorylation; ISS:UniProtKB.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.::GO:0061097; P:regulation of protein tyrosine kinase activity; ISS:UniProtKB.
666Q9H4E5    214   RHOJ_HUMAN Rho-related GTP-binding protein Rh...1980.00000000003     63.9     26     45GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; NAS:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; IMP:UniProtKB.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
667A8XAD0    206   RHEB1_CAEBR GTP-binding protein Rheb homolog ...1860.00000000004     63.5     26     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
668Q12829    278   RB40B_HUMAN Ras-related protein Rab-40B OS=Ho...1880.00000000004     64.3     25     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
669P32253    189   RASC_DICDI Ras-like protein rasC OS=Dictyoste...1830.00000000004     63.2     27     43GO:0005622; C:intracellular; IC:dictyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0031982; C:vesicle; IDA:dictyBase.
GO:0005525; F:GTP binding; IDA:dictyBase.::GO:0003924; F:GTPase activity; IDA:dictyBase.
GO:0030036; P:actin cytoskeleton organization; IMP:dictyBase.::GO:0007190; P:activation of adenylate cyclase activity; IGI:dictyBase.::GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0008283; P:cell proliferation; IGI:dictyBase.::GO:0006928; P:cellular component movement; IMP:dictyBase.::GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0043326; P:chemotaxis to folate; IMP:dictyBase.::GO:0007163; P:establishment or maintenance of cell polarity; IMP:dictyBase.::GO:0007188; P:G-protein signaling, coupled to cAMP nucleotide second messenger; IMP:dictyBase.::GO:0031276; P:negative regulation of lateral pseudopodium assembly; IMP:dictyBase.::GO:0030828; P:positive regulation of cGMP biosynthetic process; IMP:dictyBase.::GO:0051491; P:positive regulation of filopodium assembly; IMP:dictyBase.::GO:0031284; P:positive regulation of guanylate cyclase activity; IMP:dictyBase.::GO:0043406; P:positive regulation of MAP kinase activity; IMP:dictyBase.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:dictyBase.::GO:0043491; P:protein kinase B signaling cascade; IMP:dictyBase.::GO:0007265; P:Ras protein signal transduction; IDA:dictyBase.::GO:0001558; P:regulation of cell growth; IMP:dictyBase.
670O42277    188   RASK_ORYLA GTPase KRas OS=Oryzias latipes (Me...1860.00000000004     63.2     28     48GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
671Q5EFX7    188   RASK_KRYMA GTPase KRas OS=Kryptolebias marmor...1860.00000000004     62.8     28     48GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
672P22279    198   RAS2_MUCCL Ras-like protein 2 OS=lusitanicus)...1870.00000000005     63.2     23     45GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
673Q8VHP8    278   RB40B_MOUSE Ras-related protein Rab-40B OS=Mu...1890.00000000005     64.3     27     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
674Q9ER71    214   RHOJ_MOUSE Rho-related GTP-binding protein Rh...1870.00000000005     63.2     26     45GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0008360; P:regulation of cell shape; IDA:MGI.::GO:0007266; P:Rho protein signal transduction; IDA:MGI.
675Q5R9F4    244   RND3_PONAB Rho-related GTP-binding protein Rh...1290.00000000007     63.5     27     53GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
676Q6EP31    197   RAC5_ORYSJ Rac-like GTP-binding protein 5 OS=...1840.00000000007     62.4     26     47
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
677Q6SA80    244   RND3_RAT Rho-related GTP-binding protein RhoE...1290.00000000007     63.2     27     53GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
678P61588    244   RND3_MOUSE Rho-related GTP-binding protein Rh...1290.00000000007     63.2     27     53GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
679P61587    244   RND3_HUMAN Rho-related GTP-binding protein Rh...1290.00000000007     63.2     27     53GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; TAS:ProtInc.::GO:0003924; F:GTPase activity; TAS:ProtInc.
GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0007155; P:cell adhesion; TAS:ProtInc.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
680Q9HBH0    211   RHOF_HUMAN Rho-related GTP-binding protein Rh...2080.00000000008     62.8     24     45GO:0005856; C:cytoskeleton; NAS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; NAS:UniProtKB.
GO:0007015; P:actin filament organization; IDA:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
681Q29HY3    191   CDC42_DROPS Cdc42 homolog OS=Drosophila pseud...1900.0000000001     62     26     48GO:0005912; C:adherens junction; ISS:UniProtKB.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0045185; P:maintenance of protein location; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045860; P:positive regulation of protein kinase activity; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
682Q8BLR7    232   RND1_MOUSE Rho-related GTP-binding protein Rh...1900.0000000001     62.8     25     48GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
683P34144    194   RAC1A_DICDI Rho-related protein rac1A OS=Dict...2150.0000000001     62     25     45GO:0045335; C:phagocytic vesicle; IDA:dictyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:dictyBase.
GO:0030838; P:positive regulation of actin filament polymerization; IDA:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
684P60764    192   RAC3_MOUSE Ras-related C3 botulinum toxin sub...1900.0000000001     62     26     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0012505; C:endomembrane system; ISS:UniProtKB.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0030031; P:cell projection assembly; ISS:UniProtKB.::GO:0050885; P:neuromuscular process controlling balance; IMP:MGI.::GO:0031175; P:neuron projection development; IDA:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
685P60763    192   RAC3_HUMAN Ras-related C3 botulinum toxin sub...1900.0000000001     62     26     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0012505; C:endomembrane system; IDA:UniProtKB.::GO:0031941; C:filamentous actin; IDA:MGI.::GO:0030426; C:growth cone; IDA:MGI.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0030031; P:cell projection assembly; IDA:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
686P40792    192   RAC1_DROME Ras-related protein Rac1 OS=Drosop...1880.0000000001     62     25     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0016028; C:rhabdomere; IDA:FlyBase.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; NAS:FlyBase.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0051017; P:actin filament bundle assembly; IMP:FlyBase.::GO:0034334; P:adherens junction maintenance; IMP:FlyBase.::GO:0048675; P:axon extension; IMP:FlyBase.::GO:0007413; P:axonal fasciculation; IMP:FlyBase.::GO:0007298; P:border follicle cell migration; IMP:FlyBase.::GO:0035212; P:cell competition in a multicellular organism; IMP:FlyBase.::GO:0048813; P:dendrite morphogenesis; TAS:FlyBase.::GO:0046843; P:dorsal appendage formation; IMP:FlyBase.::GO:0046664; P:dorsal closure, amnioserosa morphology change; IMP:FlyBase.::GO:0007394; P:dorsal closure, elongation of leading edge cells; IMP:FlyBase.::GO:0042067; P:establishment of ommatidial planar polarity; NAS:FlyBase.::GO:0007390; P:germ-band shortening; IMP:FlyBase.::GO:0008347; P:glial cell migration; IMP:FlyBase.::GO:0008258; P:head involution; IMP:FlyBase.::GO:0007516; P:hemocyte development; IMP:FlyBase.::GO:0035099; P:hemocyte migration; IMP:FlyBase.::GO:0035320; P:imaginal disc-derived wing hair site selection; IMP:FlyBase.::GO:0002433; P:immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; IDA:FlyBase.::GO:0007254; P:JNK cascade; IMP:FlyBase.::GO:0030032; P:lamellipodium assembly; IMP:FlyBase.::GO:0008078; P:mesodermal cell migration; IMP:FlyBase.::GO:0007017; P:microtubule-based process; NAS:FlyBase.::GO:0016335; P:morphogenesis of larval imaginal disc epithelium; TAS:FlyBase.::GO:0008045; P:motor axon guidance; IMP:FlyBase.::GO:0048747; P:muscle fiber development; IMP:FlyBase.::GO:0007520; P:myoblast fusion; IMP:FlyBase.::GO:0051450; P:myoblast proliferation; IMP:FlyBase.::GO:0010593; P:negative regulation of lamellipodium assembly; IMP:FlyBase.::GO:0007422; P:peripheral nervous system development; IMP:FlyBase.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050770; P:regulation of axonogenesis; IGI:FlyBase.::GO:0048814; P:regulation of dendrite morphogenesis; IMP:FlyBase.::GO:0045610; P:regulation of hemocyte differentiation; IMP:FlyBase.::GO:0051963; P:regulation of synapse assembly; IMP:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0042052; P:rhabdomere development; IMP:FlyBase.::GO:0007435; P:salivary gland morphogenesis; IMP:FlyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0007426; P:tracheal outgrowth, open tracheal system; IGI:FlyBase.::GO:0007419; P:ventral cord development; IMP:FlyBase.
687Q4R4R6    191   CDC42_MACFA Cell division control protein 42 ...1900.0000000001     61.6     26     48GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0072686; C:mitotic spindle; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0051233; C:spindle midzone; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; ISS:UniProtKB.::GO:0051489; P:regulation of filopodium assembly; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
688Q07983    188   RASK_MONDO GTPase KRas OS=Monodelphis domesti...1860.0000000001     61.6     28     48GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
689Q38902    197   RAC1_ARATH Rac-like GTP-binding protein ARAC1...1840.0000000001     61.6     26     47GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0009524; C:phragmoplast; IDA:TAIR.::GO:0005819; C:spindle; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; TAS:TAIR.::GO:0009734; P:auxin mediated signaling pathway; IMP:TAIR.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
690P19073    191   CDC42_YEAST Cell division control protein 42 ...1890.0000000002     61.6     25     47GO:0005935; C:cellular bud neck; TAS:SGD.::GO:0005934; C:cellular bud tip; TAS:SGD.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD.::GO:0005625; C:soluble fraction; IDA:SGD.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; TAS:SGD.
GO:0007118; P:budding cell apical bud growth; IMP:SGD.::GO:0007119; P:budding cell isotropic bud growth; IMP:SGD.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030010; P:establishment of cell polarity; TAS:SGD.::GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; IGI:SGD.::GO:0045921; P:positive regulation of exocytosis; IPI:SGD.::GO:0007124; P:pseudohyphal growth; IMP:SGD.::GO:0007096; P:regulation of exit from mitosis; IMP:SGD.::GO:0031384; P:regulation of initiation of mating projection growth; IMP:SGD.::GO:0032889; P:regulation of vacuole fusion, non-autophagic; IMP:SGD.::GO:0007266; P:Rho protein signal transduction; TAS:SGD.
691O77683    244   RND3_PIG Rho-related GTP-binding protein RhoE...1290.0000000002     62.4     26     53GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
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