Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKR014C
Length:
234
Number of sequences:
5887
Description:
YKR014C YPT52 SGDID:S000001722, Chr XI from 466071-465367, Genome Release 64-1-1, reverse complement, Verified ORF, "Rab family GTPase, similar to Ypt51p and Ypt53p and to mammalian rab5; required for vacuolar protein sorting and endocytosis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
571P17081    205   RHOQ_HUMAN Rho-related GTP-binding protein Rh...1890.0000000000002     69.7     28     49GO:0005884; C:actin filament; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:BHF-UCL.
GO:0032427; F:GBD domain binding; IPI:BHF-UCL.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:BHF-UCL.::GO:0005522; F:profilin binding; IPI:BHF-UCL.
GO:0030866; P:cortical actin cytoskeleton organization; IMP:BHF-UCL.::GO:0008286; P:insulin receptor signaling pathway; IMP:BHF-UCL.::GO:0090005; P:negative regulation of establishment of protein localization in plasma membrane; IMP:BHF-UCL.::GO:0051491; P:positive regulation of filopodium assembly; IDA:BHF-UCL.::GO:0046326; P:positive regulation of glucose import; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0032956; P:regulation of actin cytoskeleton organization; IC:BHF-UCL.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
572Q55CB0    213   RASU_DICDI Ras-like protein rasU OS=Dictyoste...1970.0000000000002     69.7     25     47GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; ISS:dictyBase.::GO:0003924; F:GTPase activity; ISS:dictyBase.
GO:0007265; P:Ras protein signal transduction; ISS:dictyBase.
573Q5RDM6    184   RAP1B_PONAB Ras-related protein Rap-1b OS=Pon...1900.0000000000003     68.9     28     46GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.
574A5A6J7    184   RAP1B_PANTR Ras-related protein Rap-1b OS=Pan...1900.0000000000003     68.9     28     46GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.
575Q99JI6    184   RAP1B_MOUSE Ras-related protein Rap-1b OS=Mus...1900.0000000000003     68.9     28     46GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:MGI.
GO:0008283; P:cell proliferation; IPI:MGI.::GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IDA:MGI.
576Q4R9D4    184   RAP1B_MACFA Ras-related protein Rap-1b OS=Mac...1900.0000000000003     68.9     28     46GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
577P61224    184   RAP1B_HUMAN Ras-related protein Rap-1b OS=Hom...1900.0000000000003     68.9     28     46GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005811; C:lipid particle; IDA:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0019003; F:GDP binding; IDA:UniProtKB.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:2000114; P:regulation of establishment of cell polarity; IMP:UniProtKB.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
578Q5ZHX1    184   RAP1B_CHICK Ras-related protein Rap-1b OS=Gal...1900.0000000000003     68.9     28     46GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
579P61223    184   RAP1B_BOVIN Ras-related protein Rap-1b OS=Bos...1900.0000000000003     68.9     28     46GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.
580Q62636    184   RAP1B_RAT Ras-related protein Rap-1b OS=Rattu...1900.0000000000003     68.9     28     46GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.
581Q9HF51    224   RHO3_ASHGO GTP-binding protein RHO3 OS=Y-1056...1980.0000000000004     69.3     27     46GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
582Q9JJL4    205   RHOQ_RAT Rho-related GTP-binding protein RhoQ...1890.0000000000004     68.9     27     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
583Q8R527    205   RHOQ_MOUSE Rho-related GTP-binding protein Rh...1890.0000000000004     68.9     27     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:MGI.
GO:0030866; P:cortical actin cytoskeleton organization; IMP:BHF-UCL.::GO:0090005; P:negative regulation of establishment of protein localization in plasma membrane; IDA:BHF-UCL.::GO:0046325; P:negative regulation of glucose import; IC:BHF-UCL.::GO:0008360; P:regulation of cell shape; IDA:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
584A6NIZ1    184   RP1BL_HUMAN Ras-related protein Rap-1b-like p...1900.0000000000004     68.6     28     46GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
585P22123    184   RAPA_DISOM Ras-related protein O-Krev OS=Disc...1910.0000000000004     68.6     27     46GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
586P70426    219   RIT1_MOUSE GTP-binding protein Rit1 OS=Mus mu...2050.0000000000006     68.6     26     44GO:0005886; C:plasma membrane; IDA:MGI.
GO:0005525; F:GTP binding; IDA:MGI.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
587P13856    272   RSR1_YEAST Ras-related protein RSR1 OS=Saccha...2330.0000000000006     69.3     27     45GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:SGD.::GO:0004871; F:signal transducer activity; TAS:SGD.
GO:0007120; P:axial cellular bud site selection; TAS:SGD.::GO:0007121; P:bipolar cellular bud site selection; TAS:SGD.::GO:0007264; P:small GTPase mediated signal transduction; TAS:SGD.
588Q92963    219   RIT1_HUMAN GTP-binding protein Rit1 OS=Homo s...2050.0000000000007     68.6     25     44GO:0005886; C:plasma membrane; TAS:ProtInc.
GO:0005516; F:calmodulin binding; TAS:ProtInc.::GO:0005525; F:GTP binding; TAS:ProtInc.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
589Q9D0P8    186   IFT27_MOUSE Intraflagellar transport protein ...2020.0000000000007     68.2     24     47
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
590Q7TNZ5    183   REBL1_RAT GTPase RhebL1 OS=Rattus norvegicus ...1820.0000000000008     67.8     26     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
591P34148    195   RACB_DICDI Rho-related protein racB OS=Dictyo...2120.0000000000008     67.8     24     48GO:0005737; C:cytoplasm; IDA:dictyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:dictyBase.
GO:0030041; P:actin filament polymerization; IMP:dictyBase.::GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
592Q8BYP3    211   RHOF_MOUSE Rho-related GTP-binding protein Rh...2070.000000000001     68.2     26     47GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
593Q91806    189   RASN_XENLA GTPase NRas OS=Xenopus laevis (Afr...2000.000000000001     67.4     29     49GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
594Q0VCN3    186   IFT27_BOVIN Intraflagellar transport protein ...2020.000000000002     67     23     46
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
595P84096    191   RHOG_MOUSE Rho-related GTP-binding protein Rh...1900.000000000002     67     26     46GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.
GO:0032863; P:activation of Rac GTPase activity; ISS:UniProtKB.::GO:0060326; P:cell chemotaxis; ISS:UniProtKB.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; ISS:UniProtKB.
596P84095    191   RHOG_HUMAN Rho-related GTP-binding protein Rh...1900.000000000002     67     26     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:MGI.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; IDA:MGI.::GO:0032863; P:activation of Rac GTPase activity; IMP:UniProtKB.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0060326; P:cell chemotaxis; IMP:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:MGI.::GO:0016601; P:Rac protein signal transduction; IDA:MGI.::GO:0007266; P:Rho protein signal transduction; IDA:MGI.
597P84097    191   RHOG_CRICR Rho-related GTP-binding protein Rh...1900.000000000002     67     26     46GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0032863; P:activation of Rac GTPase activity; ISS:UniProtKB.::GO:0060326; P:cell chemotaxis; ISS:UniProtKB.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
598Q8VHQ4    281   RB40C_MOUSE Ras-related protein Rab-40C OS=Mu...2040.000000000002     68.6     26     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
599Q96S21    281   RB40C_HUMAN Ras-related protein Rab-40C OS=Ho...2040.000000000002     68.6     26     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
600Q01387    229   RAS2_NEUCR Protein ras-2 OS=1257 / FGSC 987)....1910.000000000002     67.4     28     47GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
601Q96A58    199   RERG_HUMAN Ras-related and estrogen-regulated...1910.000000000002     67     31     47GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0016020; C:membrane; IEA:InterPro.::GO:0005634; C:nucleus; IDA:HPA.
GO:0030331; F:estrogen receptor binding; NAS:UniProtKB.::GO:0019003; F:GDP binding; TAS:UniProtKB.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0009725; P:response to hormone stimulus; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
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