Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKR014C
Length:
234
Number of sequences:
5887
Description:
YKR014C YPT52 SGDID:S000001722, Chr XI from 466071-465367, Genome Release 64-1-1, reverse complement, Verified ORF, "Rab family GTPase, similar to Ypt51p and Ypt53p and to mammalian rab5; required for vacuolar protein sorting and endocytosis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
541Q6IP71    206   RALBB_XENLA Ras-related protein ralB-B OS=Xen...1900.00000000000001     73.2     27     51GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0007265; P:Ras protein signal transduction; ISS:UniProtKB.::GO:0048070; P:regulation of developmental pigmentation; ISS:UniProtKB.
542Q95KD9    199   DIRA2_MACFA GTP-binding protein Di-Ras2 OS=Ma...2030.00000000000001     73.2     29     47GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
543P01114    248   RASH_RRASV Transforming protein p29 OS=Rashee...1860.00000000000002     73.6     27     46GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0019028; C:viral capsid; IEA:InterPro.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
544P08645    184   RAS3_DROME Ras-like protein 3 OS=Drosophila m...1890.00000000000002     72.8     28     47GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007155; P:cell adhesion; IMP:FlyBase.::GO:0007391; P:dorsal closure; IMP:FlyBase.::GO:0030718; P:germ-line stem cell maintenance; IGI:FlyBase.::GO:0035099; P:hemocyte migration; IMP:FlyBase.::GO:0030713; P:ovarian follicle cell stalk formation; TAS:FlyBase.::GO:0016476; P:regulation of embryonic cell shape; IMP:FlyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0006930; P:substrate-dependent cell migration, cell extension; IMP:FlyBase.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
545O13928    205   RHO3_SCHPO GTP-binding protein rho3 OS=Schizo...1880.00000000000002     72.8     30     46GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0030036; P:actin cytoskeleton organization; IMP:PomBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007163; P:establishment or maintenance of cell polarity; IMP:PomBase.::GO:0000226; P:microtubule cytoskeleton organization; IMP:PomBase.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0010590; P:regulation of cytokinetic cell separation; IMP:PomBase.::GO:0017157; P:regulation of exocytosis; TAS:PomBase.::GO:0007264; P:small GTPase mediated signal transduction; IC:PomBase.
546Q55BW0    278   RAPC_DICDI Ras-related protein rapC OS=Dictyo...2190.00000000000002     73.9     29     47GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
547Q5R6S2    199   DIRA2_PONAB GTP-binding protein Di-Ras2 OS=Po...2030.00000000000002     72.8     29     47GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
548Q9VND8    182   RHEB_DROME GTP-binding protein Rheb homolog O...1840.00000000000002     72.4     29     48GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:FlyBase.
GO:0016049; P:cell growth; IMP:FlyBase.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:FlyBase.::GO:0030307; P:positive regulation of cell growth; TAS:FlyBase.::GO:0045793; P:positive regulation of cell size; IMP:FlyBase.::GO:0090070; P:positive regulation of ribosome biogenesis; IMP:FlyBase.::GO:0045727; P:positive regulation of translation; IMP:FlyBase.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:FlyBase.::GO:0042594; P:response to starvation; IEP:FlyBase.::GO:0042254; P:ribosome biogenesis; IDA:FlyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
549Q23862    223   RACE_DICDI Rho-related protein racE OS=Dictyo...1860.00000000000002     72.8     30     49GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0019953; P:sexual reproduction; IEP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
550P63320    206   RALA_SAGOE Ras-related protein Ral-A OS=Sagui...1850.00000000000002     72.4     28     49GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0031755; F:Edg-2 lysophosphatidic acid receptor binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0051665; P:membrane raft localization; ISS:UniProtKB.::GO:0017157; P:regulation of exocytosis; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
551P63322    206   RALA_RAT Ras-related protein Ral-A OS=Rattus ...1850.00000000000002     72.4     28     49GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0031755; F:Edg-2 lysophosphatidic acid receptor binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; NAS:RGD.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0051665; P:membrane raft localization; ISS:UniProtKB.::GO:0017157; P:regulation of exocytosis; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
552P63321    206   RALA_MOUSE Ras-related protein Ral-A OS=Mus m...1850.00000000000002     72.4     28     49GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0031755; F:Edg-2 lysophosphatidic acid receptor binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0051665; P:membrane raft localization; IDA:UniProtKB.::GO:0017157; P:regulation of exocytosis; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
553P01115    241   RASH_MSVHA Transforming protein p29 OS=Harvey...1860.00000000000002     72.8     26     46GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
554Q55CA9    214   RASZ_DICDI Ras-like protein rasZ OS=Dictyoste...1840.00000000000003     72.4     26     49GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; ISS:dictyBase.
GO:0007265; P:Ras protein signal transduction; ISS:dictyBase.::GO:0019953; P:sexual reproduction; IEP:dictyBase.
555Q9YH37    184   RAP1B_CYPCA Ras-related protein Rap-1b OS=Cyp...1900.00000000000004     71.6     29     47GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
556P34149    192   RACC_DICDI Rho-related protein racC OS=Dictyo...1980.00000000000004     71.6     28     48GO:0031252; C:cell leading edge; IDA:dictyBase.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IDA:dictyBase.::GO:0019901; F:protein kinase binding; IPI:dictyBase.
GO:0016477; P:cell migration; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0045184; P:establishment of protein localization; IMP:dictyBase.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; IMP:dictyBase.::GO:0030838; P:positive regulation of actin filament polymerization; IDA:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
557Q5PR73    199   DIRA2_MOUSE GTP-binding protein Di-Ras2 OS=Mu...2030.00000000000004     71.6     28     47GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
558O00212    210   RHOD_HUMAN Rho-related GTP-binding protein Rh...1890.00000000000005     71.6     25     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007266; P:Rho protein signal transduction; TAS:ProtInc.
559Q38912    198   RAC3_ARATH Rac-like GTP-binding protein ARAC3...1840.00000000000005     71.6     30     47GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005730; C:nucleolus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0030427; C:site of polarized growth; IDA:TAIR.::GO:0005819; C:spindle; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:TAIR.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
560P38545    214   RAN_PLAFA GTP-binding nuclear protein Ran OS=...1910.00000000000006     71.6     25     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
561Q9BW83    186   IFT27_HUMAN Intraflagellar transport protein ...2020.00000000000007     70.9     24     47GO:0030992; C:intraflagellar transport particle B; ISS:BHF-UCL.::GO:0009434; C:microtubule-based flagellum; ISS:BHF-UCL.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
562Q6TEN1    184   RAP1B_DANRE Ras-related protein Rap-1b OS=Dan...1900.00000000000009     70.5     28     47GO:0005911; C:cell-cell junction; IMP:ZFIN.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0060026; P:convergent extension; IMP:ZFIN.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
563Q10133    200   RHO2_SCHPO GTP-binding protein rho2 OS=Schizo...1880.00000000000009     70.9     28     49GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0030427; C:site of polarized growth; IDA:PomBase.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IMP:PomBase.::GO:0032949; P:regulation of alpha-glucan biosynthetic process; IGI:PomBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
564Q640R7    184   RAP1B_XENTR Ras-related protein Rap-1b OS=Xen...1900.0000000000001     70.5     28     47GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
565Q7ZXH7    184   RAP1B_XENLA Ras-related protein Rap-1b OS=Xen...1900.0000000000001     70.5     28     47GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
566P38544    215   RAN_ONCVO GTP-binding nuclear protein Ran OS=...1260.0000000000001     70.5     32     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
567P70425    217   RIT2_MOUSE GTP-binding protein Rit2 OS=Mus mu...2080.0000000000001     70.5     25     46GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
568P32254    194   RASS_DICDI Ras-like protein rasS OS=Dictyoste...1900.0000000000001     70.1     31     45GO:0005622; C:intracellular; IC:dictyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; ISS:dictyBase.::GO:0003924; F:GTPase activity; ISS:dictyBase.::GO:0005515; F:protein binding; IPI:dictyBase.
GO:0007015; P:actin filament organization; IMP:dictyBase.::GO:0000902; P:cell morphogenesis; IMP:dictyBase.::GO:0006928; P:cellular component movement; IMP:dictyBase.::GO:0030866; P:cortical actin cytoskeleton organization; IMP:dictyBase.::GO:0051271; P:negative regulation of cellular component movement; IMP:dictyBase.::GO:0050766; P:positive regulation of phagocytosis; IMP:dictyBase.::GO:0007265; P:Ras protein signal transduction; ISS:dictyBase.::GO:0042127; P:regulation of cell proliferation; IMP:dictyBase.::GO:0019953; P:sexual reproduction; IEP:dictyBase.
569Q5BJQ5    217   RIT2_RAT GTP-binding protein Rit2 OS=Rattus n...2080.0000000000002     70.5     25     46GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
570P18613    186   RAPA_DICDI Ras-related protein rapA OS=Dictyo...1880.0000000000002     69.7     28     48GO:0045335; C:phagocytic vesicle; IDA:dictyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IDA:dictyBase.::GO:0003924; F:GTPase activity; IDA:dictyBase.::GO:0017160; F:Ral GTPase binding; IDA:dictyBase.
GO:0031289; P:actin phosphorylation; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0006972; P:hyperosmotic response; IMP:dictyBase.::GO:0030838; P:positive regulation of actin filament polymerization; IEP:dictyBase.::GO:0031284; P:positive regulation of guanylate cyclase activity; IMP:dictyBase.::GO:0043520; P:regulation of myosin II filament assembly; IMP:dictyBase.::GO:0046578; P:regulation of Ras protein signal transduction; IDA:dictyBase.::GO:0009409; P:response to cold; IEP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
571P17081    205   RHOQ_HUMAN Rho-related GTP-binding protein Rh...1890.0000000000002     69.7     28     49GO:0005884; C:actin filament; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:BHF-UCL.
GO:0032427; F:GBD domain binding; IPI:BHF-UCL.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:BHF-UCL.::GO:0005522; F:profilin binding; IPI:BHF-UCL.
GO:0030866; P:cortical actin cytoskeleton organization; IMP:BHF-UCL.::GO:0008286; P:insulin receptor signaling pathway; IMP:BHF-UCL.::GO:0090005; P:negative regulation of establishment of protein localization in plasma membrane; IMP:BHF-UCL.::GO:0051491; P:positive regulation of filopodium assembly; IDA:BHF-UCL.::GO:0046326; P:positive regulation of glucose import; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0032956; P:regulation of actin cytoskeleton organization; IC:BHF-UCL.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
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