UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YKR014C

Length:

234

Number of sequences:

5887

Description:

YKR014C YPT52 SGDID:S000001722, Chr XI from 466071-465367, Genome Release 64-1-1, reverse complement, Verified ORF, "Rab family GTPase, similar to Ypt51p and Ypt53p and to mammalian rab5; required for vacuolar protein sorting and endocytosis"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
361	Q1HE58	221	RB27A_CANFA Ras-related protein Rab-27A OS=Ca...	194	3e-23	98.2	31	52	GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
									GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
362	Q9XER8	207	RAB7_GOSHI Ras-related protein Rab7 OS=Gossyp...	220	3e-23	97.8	30	50	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
363	Q5RI75	627	RASEF_MOUSE Ras and EF-hand domain-containing...	181	5e-23	101	35	52	GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
364	Q43463	206	RAB7_SOYBN Ras-related protein Rab7 OS=Glycin...	192	5e-23	97.4	31	52	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
365	P18067	207	RAB7A_CANFA Ras-related protein Rab-7a OS=Can...	191	6e-23	97.1	29	52	GO:0005770; C:late endosome; ISS:UniProtKB.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0045022; P:early endosome to late endosome transport; IMP:UniProtKB.::GO:0007174; P:epidermal growth factor catabolic process; IMP:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
366	Q5R9Y4	207	RAB7A_PONAB Ras-related protein Rab-7a OS=Pon...	191	6e-23	97.1	29	52	GO:0005770; C:late endosome; ISS:UniProtKB.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0045022; P:early endosome to late endosome transport; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
367	Q948K6	204	RABG1_ARATH Ras-related protein RABG1 OS=Arab...	194	6e-23	97.1	32	51	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
368	P09527	207	RAB7A_RAT Ras-related protein Rab-7a OS=Rattu...	191	7e-23	97.1	29	52	GO:0097208; C:alveolar lamellar body; IDA:RGD.::GO:0005770; C:late endosome; IDA:RGD.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; IEA:UniProtKB-SubCell.
									GO:0019003; F:GDP binding; IDA:RGD.::GO:0005525; F:GTP binding; IDA:RGD.::GO:0003924; F:GTPase activity; TAS:RGD.::GO:0048365; F:Rac GTPase binding; IPI:RGD.
									GO:0045453; P:bone resorption; IMP:RGD.::GO:0045022; P:early endosome to late endosome transport; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
369	P51151	201	RAB9A_HUMAN Ras-related protein Rab-9A OS=Hom...	235	7e-23	97.1	29	48	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005770; C:late endosome; IDA:MGI.::GO:0005764; C:lysosome; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0019003; F:GDP binding; IDA:UniProtKB.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0045921; P:positive regulation of exocytosis; IMP:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
370	P51150	207	RAB7A_MOUSE Ras-related protein Rab-7a OS=Mus...	191	7e-23	97.1	29	52	GO:0005794; C:Golgi apparatus; IDA:MGI.::GO:0005770; C:late endosome; IDA:MGI.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0045022; P:early endosome to late endosome transport; ISS:UniProtKB.::GO:0006886; P:intracellular protein transport; TAS:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
371	P51149	207	RAB7A_HUMAN Ras-related protein Rab-7a OS=Hom...	191	7e-23	97.1	29	52	GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005770; C:late endosome; IDA:UniProtKB.::GO:0005764; C:lysosome; IDA:MGI.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; IEA:UniProtKB-SubCell.
									GO:0019003; F:GDP binding; IDA:BHF-UCL.::GO:0005525; F:GTP binding; IDA:BHF-UCL.::GO:0003924; F:GTPase activity; IDA:BHF-UCL.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0045022; P:early endosome to late endosome transport; IMP:UniProtKB.::GO:0006897; P:endocytosis; TAS:ProtInc.::GO:0008333; P:endosome to lysosome transport; IMP:BHF-UCL.::GO:0007174; P:epidermal growth factor catabolic process; IMP:BHF-UCL.::GO:0090382; P:phagosome maturation; TAS:UniProtKB.::GO:0015031; P:protein transport; TAS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
372	Q9ULC3	237	RAB23_HUMAN Ras-related protein Rab-23 OS=Hom...	258	7e-23	97.4	29	48	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
373	Q3T0F5	207	RAB7A_BOVIN Ras-related protein Rab-7a OS=Bos...	190	8e-23	96.7	29	53	GO:0005770; C:late endosome; ISS:UniProtKB.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0045022; P:early endosome to late endosome transport; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
374	P36864	205	YPTV5_VOLCA GTP-binding protein yptV5 OS=Volv...	128	8e-23	96.7	38	60	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
375	P51159	221	RB27A_HUMAN Ras-related protein Rab-27A OS=Ho...	194	9e-23	97.1	31	51	GO:0030425; C:dendrite; IDA:UniProtKB.::GO:0070382; C:exocytic vesicle; IDA:UniProtKB.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0042470; C:melanosome; IDA:UniProtKB.::GO:0032585; C:multivesicular body membrane; IDA:UniProtKB.
									GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
									GO:0071985; P:multivesicular body sorting pathway; IMP:UniProtKB.::GO:0045921; P:positive regulation of exocytosis; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
376	P24408	201	RAB9A_CANFA Ras-related protein Rab-9A OS=Can...	189	9e-23	96.7	31	50	GO:0005770; C:late endosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
377	Q7Z6P3	723	RAB44_HUMAN Ras-related protein Rab-44 OS=Hom...	190	1e-22	100	34	53	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
378	Q5R7A4	203	RAB7L_PONAB Ras-related protein Rab-7L1 OS=Po...	234	2e-22	95.9	27	53	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
379	O14966	203	RAB7L_HUMAN Ras-related protein Rab-7L1 OS=Ho...	234	2e-22	95.9	27	53	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
380	Q14088	237	RB33A_HUMAN Ras-related protein Rab-33A OS=Ho...	194	2e-22	96.3	31	50	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
381	P97950	237	RB33A_MOUSE Ras-related protein Rab-33A OS=Mu...	194	2e-22	96.3	32	52	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
382	Q9HDY0	208	YPT71_SCHPO GTP-binding protein ypt71 OS=Schi...	192	2e-22	95.5	28	49	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005744; C:mitochondrial inner membrane presequence translocase complex; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005773; C:vacuole; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IC:PomBase.::GO:0003924; F:GTPase activity; ISS:PomBase.
									GO:0006897; P:endocytosis; ISS:PomBase.::GO:0006896; P:Golgi to vacuole transport; ISS:PomBase.::GO:0006886; P:intracellular protein transport; IC:PomBase.::GO:0061192; P:negative regulation of vacuole fusion, non-autophagic; IMP:PomBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
383	Q54E92	196	RABG1_DICDI Ras-related protein RabG1 OS=Dict...	192	3e-22	95.1	32	54	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
384	Q9SJ11	212	RABG2_ARATH Ras-related protein RABG2 OS=Arab...	192	3e-22	95.5	30	53	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
385	Q8CAM5	267	RAB36_MOUSE Ras-related protein Rab-36 OS=Mus...	235	3e-22	96.3	28	46	GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
386	P35284	197	RAB12_RAT Ras-related protein Rab-12 OS=Rattu...	179	6e-22	94.4	34	53	GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0030141; C:secretory granule; IDA:RGD.
									GO:0005525; F:GTP binding; TAS:RGD.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
387	Q8BHH2	201	RAB9B_MOUSE Ras-related protein Rab-9B OS=Mus...	191	7e-22	94	34	49	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
388	O97572	207	RAB7A_RABIT Ras-related protein Rab-7a OS=Ory...	191	7e-22	94.4	29	53	GO:0005770; C:late endosome; ISS:UniProtKB.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0045022; P:early endosome to late endosome transport; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
389	Q41640	206	RAB7_VIGAC Ras-related protein Rab7 OS=Vigna ...	192	8e-22	94	30	52	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
390	P35288	237	RAB23_MOUSE Ras-related protein Rab-23 OS=Mus...	258	8e-22	94.7	27	45	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
391	Q8VEA8	199	RAB7B_MOUSE Ras-related protein Rab-7b OS=Mus...	191	9e-22	93.6	29	53	GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005770; C:late endosome; IDA:UniProtKB.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0005802; C:trans-Golgi network; ISS:UniProtKB.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0034499; P:late endosome to Golgi transport; ISS:UniProtKB.::GO:0034144; P:negative regulation of toll-like receptor 4 signaling pathway; IMP:UniProtKB.::GO:0034164; P:negative regulation of toll-like receptor 9 signaling pathway; IMP:UniProtKB.::GO:0032755; P:positive regulation of interleukin-6 production; ISS:UniProtKB.::GO:0045654; P:positive regulation of megakaryocyte differentiation; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.

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