UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YKR009C

Length:

900

Number of sequences:

5887

Description:

YKR009C FOX2 SGDID:S000001717, Chr XI from 457054-454352, Genome Release 64-1-1, reverse complement, Verified ORF, "Multifunctional enzyme of the peroxisomal fatty acid beta-oxidation pathway; has 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	Q02207	900	FOX2_YEAST Peroxisomal hydratase-dehydrogenas...	900	0	1854	100	100	GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
									GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IDA:SGD.::GO:0004300; F:enoyl-CoA hydratase activity; IDA:SGD.::GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0006635; P:fatty acid beta-oxidation; IMP:SGD.
2	P22414	906	FOX2_CANTR Peroxisomal hydratase-dehydrogenas...	919	0	941	53	70	GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
									GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.::GO:0016829; F:lyase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:EC.
									GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
3	Q01373	894	FOX2_NEUCR Peroxisomal hydratase-dehydrogenas...	894	0	811	49	65	GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
									GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.::GO:0016829; F:lyase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:EC.
									GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
4	P51659	736	DHB4_HUMAN Peroxisomal multifunctional enzyme...	282	5e-95	321	55	74	GO:0005782; C:peroxisomal matrix; TAS:Reactome.
									GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; TAS:Reactome.::GO:0033989; F:3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity; TAS:Reactome.::GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.::GO:0016508; F:long-chain-enoyl-CoA hydratase activity; TAS:Reactome.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0032934; F:sterol binding; IEA:InterPro.
									GO:0008209; P:androgen metabolic process; IDA:UniProtKB.::GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.::GO:0008210; P:estrogen metabolic process; IDA:UniProtKB.::GO:0033540; P:fatty acid beta-oxidation using acyl-CoA oxidase; TAS:Reactome.
5	P97852	735	DHB4_RAT Peroxisomal multifunctional enzyme t...	282	1e-95	322	55	74	GO:0005777; C:peroxisome; IDA:HGNC.
									GO:0033989; F:3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity; IEA:EC.::GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0032934; F:sterol binding; IEA:InterPro.::GO:0030283; F:testosterone dehydrogenase [NAD(P) activity; TAS:RGD.
									GO:0008203; P:cholesterol metabolic process; NAS:RGD.::GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.]
6	P51660	735	DHB4_MOUSE Peroxisomal multifunctional enzyme...	282	2e-94	319	54	74	GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005777; C:peroxisome; IDA:MGI.
									GO:0033989; F:3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity; IEA:EC.::GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:EC.::GO:0032934; F:sterol binding; IEA:InterPro.
									GO:0006635; P:fatty acid beta-oxidation; IMP:MGI.::GO:0060009; P:Sertoli cell development; IMP:MGI.::GO:0000038; P:very long-chain fatty acid metabolic process; IMP:MGI.
7	Q9VXJ0	598	DHB4_DROME Peroxisomal multifunctional enzyme...	280	9e-88	298	55	71	GO:0005777; C:peroxisome; IC:FlyBase.
									GO:0080023; F:3R-hydroxyacyl-CoA dehydratase activity; IDA:FlyBase.::GO:0004300; F:enoyl-CoA hydratase activity; IDA:FlyBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:EC.::GO:0042803; F:protein homodimerization activity; IDA:FlyBase.
									GO:0033540; P:fatty acid beta-oxidation using acyl-CoA oxidase; IC:FlyBase.
8	Q9NKW1	441	MFEA_DICDI Peroxisomal multifunctional enzyme...	308	3e-59	213	43	59	GO:0005777; C:peroxisome; TAS:dictyBase.
									GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0032934; F:sterol binding; IEA:InterPro.
									GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
9	P96825	286	Y0148_MYCTU Putative short-chain type dehydro...	280	1e-46	173	39	54	GO:0005886; C:plasma membrane; IDA:MTBBASE.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
10	P73574	247	FABG1_SYNY3 3-oxoacyl-[acyl-carrier-protein] ...	263	5e-37	144	41	56
									GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]
11	Q9X248	246	FABG_THEMA 3-oxoacyl-[acyl-carrier-protein] r...	259	8e-35	138	33	56
									GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB.
									GO:0030497; P:fatty acid elongation; ISS:UniProtKB.]
12	P51831	246	FABG_BACSU 3-oxoacyl-[acyl-carrier-protein] r...	238	3e-35	139	38	57
									GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]
13	P33207	319	FABG_ARATH 3-oxoacyl-[acyl-carrier-protein] r...	187	4e-33	135	41	63	GO:0009941; C:chloroplast envelope; IDA:TAIR.::GO:0009570; C:chloroplast stroma; IDA:TAIR.
									GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0005507; F:copper ion binding; IDA:TAIR.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]
14	Q8VYI3	309	ECH2_ARATH Enoyl-CoA hydratase 2, peroxisomal...	291	1e-36	145	35	51	GO:0005777; C:peroxisome; IDA:TAIR.
									GO:0080023; F:3R-hydroxyacyl-CoA dehydratase activity; IDA:TAIR.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0033542; P:fatty acid beta-oxidation, unsaturated, even number; IMP:TAIR.
15	Q93X68	317	FABG5_BRANA 3-oxoacyl-[acyl-carrier-protein] ...	245	6e-36	144	40	54	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]
16	Q9KQH7	244	FABG_VIBCH 3-oxoacyl-[acyl-carrier-protein] r...	194	7e-30	124	37	59
									GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB.
									GO:0030497; P:fatty acid elongation; ISS:UniProtKB.]
17	Q949M3	315	FABG3_BRANA 3-oxoacyl-[acyl-carrier-protein] ...	248	8e-36	143	38	56	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]
18	Q93X62	320	FABG1_BRANA 3-oxoacyl-[acyl-carrier-protein] ...	248	8e-36	143	38	56	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]
19	Q93X67	328	FABG2_BRANA 3-oxoacyl-[acyl-carrier-protein] ...	248	8e-35	140	37	56	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]
20	Q949M2	254	FABG4_BRANA 3-oxoacyl-[acyl-carrier-protein] ...	248	5e-33	133	36	56	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]
21	Q54XZ0	294	MFEB_DICDI Probable enoyl-CoA hydratase 2 OS=...	268	1e-34	139	36	53	GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
									GO:0016829; F:lyase activity; IEA:UniProtKB-KW.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.
22	P28643	320	FABG_CUPLA 3-oxoacyl-[acyl-carrier-protein] r...	251	2e-31	130	39	55	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]
23	P0AEK3	244	FABG_SHIFL 3-oxoacyl-[acyl-carrier-protein] r...	192	2e-29	123	36	58
									GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB.
									GO:0030497; P:fatty acid elongation; ISS:UniProtKB.]
24	P0AEK2	244	FABG_ECOLI 3-oxoacyl-[acyl-carrier-protein] r...	192	2e-29	123	36	58
									GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IMP:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; IDA:UniProtKB.
									GO:0009102; P:biotin biosynthetic process; IMP:EcoCyc.::GO:0030497; P:fatty acid elongation; IMP:UniProtKB.]
25	P66782	247	Y1385_MYCBO Uncharacterized oxidoreductase Mb...	250	2e-28	120	35	54
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
26	P66781	247	Y1350_MYCTU Uncharacterized oxidoreductase Rv...	250	2e-28	120	35	54
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0040007; P:growth; IMP:MTBBASE.
27	Q8CPI3	244	FABG_STAES 3-oxoacyl-[acyl-carrier-protein] r...	237	4e-29	122	36	54
									GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB.
									GO:0030497; P:fatty acid elongation; ISS:UniProtKB.]
28	Q5HPW0	244	FABG_STAEQ 3-oxoacyl-[acyl-carrier-protein] r...	237	4e-29	122	36	54
									GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB.
									GO:0030497; P:fatty acid elongation; ISS:UniProtKB.]
29	P0A2C9	244	FABG_SALTY 3-oxoacyl-[acyl-carrier-protein] r...	192	5e-29	121	36	57
									GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB.
									GO:0030497; P:fatty acid elongation; IMP:UniProtKB.]
30	P0A2D0	244	FABG_SALTI 3-oxoacyl-[acyl-carrier-protein] r...	192	5e-29	121	36	57
									GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB.
									GO:0030497; P:fatty acid elongation; ISS:UniProtKB.]
31	P0A0I0	246	FABG_STAAW 3-oxoacyl-[acyl-carrier-protein] r...	233	6e-29	121	36	56
									GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB.
									GO:0030497; P:fatty acid elongation; ISS:UniProtKB.]

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