rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
271 | Q6YN16 | 418 | HSDL2_HUMAN Hydroxysteroid dehydrogenase-like... | 147 | 0.000004 | 53.9 | 30 | 48 | GO:0005777; C:peroxisome; IDA:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | | 272 | Q6PKH6 | 230 | DR4L2_HUMAN Dehydrogenase/reductase SDR famil... | 195 | 0.0000002 | 56.2 | 27 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 273 | Q8NBQ5 | 300 | DHB11_HUMAN Estradiol 17-beta-dehydrogenase 1... | 187 | 0.000000005 | 62 | 28 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005811; C:lipid particle; IDA:UniProtKB. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006710; P:androgen catabolic process; IDA:HGNC.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 274 | O75452 | 317 | RDH16_HUMAN Retinol dehydrogenase 16 OS=Homo ... | 201 | 0.61 | 37 | 24 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; TAS:ProtInc. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; TAS:ProtInc. | | | | | | | | | | GO:0006629; P:lipid metabolic process; TAS:ProtInc. | 275 | P16543 | 249 | DHK2_STRVN Granaticin polyketide synthase put... | 185 | 0.00000003 | 58.9 | 28 | 46 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW. | 276 | Q5RCH8 | 303 | PECR_PONAB Peroxisomal trans-2-enoyl-CoA redu... | 201 | 0.0004 | 47 | 24 | 46 | GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0019166; F:trans-2-enoyl-CoA reductase (NADPH) activity; IEA:EC. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 277 | Q5RJY4 | 325 | DRS7B_RAT Dehydrogenase/reductase SDR family ... | 201 | 0.00000003 | 60.1 | 27 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 278 | P50166 | 282 | ARDH_CANTR D-arabinitol 2-dehydrogenase [ribu... | 248 | 0.0000000006 | 64.7 | 28 | 47 | | | | | | | | | | | GO:0047038; F:D-arabinitol 2-dehydrogenase activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; IDA:UniProtKB. | 279 | Q9BPX1 | 270 | DHB14_HUMAN 17-beta-hydroxysteroid dehydrogen... | 162 | 0.00000001 | 60.8 | 30 | 48 | GO:0005813; C:centrosome; IDA:HPA.::GO:0005829; C:cytosol; IDA:HGNC. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:HGNC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IDA:HGNC. | | | | | | | | | | GO:0006706; P:steroid catabolic process; IDA:HGNC. | 280 | Q8VCR2 | 304 | DHB13_MOUSE 17-beta-hydroxysteroid dehydrogen... | 196 | 0.000000009 | 61.6 | 23 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 281 | P70684 | 265 | PGDH_CAVPO 15-hydroxyprostaglandin dehydrogen... | 193 | 0.000000005 | 61.6 | 30 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0097070; P:ductus arteriosus closure; ISS:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; ISS:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB. | 282 | P50164 | 260 | TRN2_HYONI Tropinone reductase 2 OS=Hyoscyamu... | 141 | 0.00002 | 50.4 | 26 | 48 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050358; F:tropinone reductase activity; IEA:EC. | | | | | | | | | | | 283 | Q11150 | 251 | Y484_MYCTU Uncharacterized oxidoreductase Rv0... | 191 | 0.000000002 | 63.2 | 28 | 45 | GO:0005886; C:plasma membrane; IDA:MTBBASE. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 284 | P19871 | 254 | 3BHD_COMTE 3-beta-hydroxysteroid dehydrogenas... | 245 | 0.00003 | 50.4 | 24 | 42 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0030283; F:testosterone dehydrogenase [NAD(P) activity; IEA:EC. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW.] | 285 | P40747 | 689 | YUXG_BACSU Uncharacterized oxidoreductase yux... | 186 | 0.00000002 | 61.6 | 30 | 48 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 286 | Q9BY49 | 303 | PECR_HUMAN Peroxisomal trans-2-enoyl-CoA redu... | 195 | 0.000002 | 53.9 | 25 | 46 | GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0019166; F:trans-2-enoyl-CoA reductase (NADPH) activity; IDA:UniProtKB. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0033306; P:phytol metabolic process; IDA:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro. | 287 | Q3T0C2 | 266 | PGDH_BOVIN 15-hydroxyprostaglandin dehydrogen... | 193 | 0.00000002 | 60.1 | 30 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; IDA:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0097070; P:ductus arteriosus closure; ISS:UniProtKB.::GO:0060206; P:estrous cycle phase; IEP:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; IDA:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB. | 288 | Q6F7B8 | 303 | ACR1_ACIAD Fatty acyl-CoA reductase OS=Acinet... | 193 | 0.0000003 | 56.6 | 30 | 48 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:EC. | | | | | | | | | | GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW. | 289 | Q21929 | 251 | DCXR_CAEEL Probable L-xylulose reductase OS=C... | 181 | 0.000001 | 53.9 | 27 | 48 | GO:0005886; C:plasma membrane; IDA:WormBase. | | | | | | | | | | GO:0050038; F:L-xylulose reductase (NADP+) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0005998; P:xylulose catabolic process; IDA:WormBase. | 290 | Q9Y394 | 339 | DHRS7_HUMAN Dehydrogenase/reductase SDR famil... | 217 | 0.000000005 | 62.4 | 27 | 44 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 291 | A6NNS2 | 312 | DRS7C_HUMAN Dehydrogenase/reductase SDR famil... | 193 | 0.00000002 | 60.5 | 26 | 50 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 292 | P50206 | 276 | BPHB_PSES1 Cis-2,3-dihydrobiphenyl-2,3-diol d... | 190 | 0.00000002 | 60.1 | 29 | 46 | | | | | | | | | | | GO:0018509; F:cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW. | 293 | Q4V8F9 | 524 | HSDL2_RAT Hydroxysteroid dehydrogenase-like p... | 147 | 0.000009 | 52.8 | 29 | 48 | GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | | 294 | Q7Z5P4 | 300 | DHB13_HUMAN 17-beta-hydroxysteroid dehydrogen... | 197 | 0.00000003 | 60.1 | 27 | 46 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 295 | P66776 | 258 | BUTA_STAAW Diacetyl reductase [(S)-acetoin fo... | 194 | 0.000000003 | 62 | 32 | 48 | | | | | | | | | | | GO:0052588; F:diacetyl reductase ((S)-acetoin forming) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045150; P:acetoin catabolic process; IEA:InterPro. | 296 | Q6GCZ8 | 258 | BUTA_STAAS Diacetyl reductase [(S)-acetoin fo... | 194 | 0.000000003 | 62 | 32 | 48 | | | | | | | | | | | GO:0052588; F:diacetyl reductase ((S)-acetoin forming) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045150; P:acetoin catabolic process; IEA:InterPro. | 297 | Q6GKH9 | 258 | BUTA_STAAR Diacetyl reductase [(S)-acetoin fo... | 194 | 0.000000003 | 62 | 32 | 48 | | | | | | | | | | | GO:0052588; F:diacetyl reductase ((S)-acetoin forming) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045150; P:acetoin catabolic process; IEA:InterPro. | 298 | P99120 | 258 | BUTA_STAAN Diacetyl reductase [(S)-acetoin fo... | 194 | 0.000000003 | 62 | 32 | 48 | | | | | | | | | | | GO:0052588; F:diacetyl reductase ((S)-acetoin forming) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045150; P:acetoin catabolic process; IEA:InterPro. | 299 | P66775 | 258 | BUTA_STAAM Diacetyl reductase [(S)-acetoin fo... | 194 | 0.000000003 | 62 | 32 | 48 | | | | | | | | | | | GO:0052588; F:diacetyl reductase ((S)-acetoin forming) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045150; P:acetoin catabolic process; IEA:InterPro. | 300 | Q5HJP2 | 258 | BUTA_STAAC Diacetyl reductase [(S)-acetoin fo... | 194 | 0.000000003 | 62 | 32 | 48 | | | | | | | | | | | GO:0052588; F:diacetyl reductase ((S)-acetoin forming) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045150; P:acetoin catabolic process; IEA:InterPro. | 301 | Q99J47 | 323 | DRS7B_MOUSE Dehydrogenase/reductase SDR famil... | 194 | 0.000000004 | 62.8 | 30 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | |